Busch Lab

ZMP

ENSDARG00000095744

Ensembl ID:
ENSDARG00000095744
Human Orthologues:
CTSL1, CTSL2
Human Descriptions:
cathepsin L1 [Source:HGNC Symbol;Acc:2537]
cathepsin L2 [Source:HGNC Symbol;Acc:2538]
Mouse Orthologues:
4930486L24Rik, BC051665, Cts3, Cts6, Cts7, Cts8, Ctsj, Ctsl, Ctsll3, Ctsm, Ctsq, Ctsr
Mouse Descriptions:
RIKEN cDNA 4930486L24 gene Gene [Source:MGI Symbol;Acc:MGI:1922258]
cDNA sequence BC051665 Gene [Source:MGI Symbol;Acc:MGI:2682300]
cathepsin 3 Gene [Source:MGI Symbol;Acc:MGI:2151929]
cathepsin 6 Gene [Source:MGI Symbol;Acc:MGI:1889619]
cathepsin 7 Gene [Source:MGI Symbol;Acc:MGI:1860262]
cathepsin 8 Gene [Source:MGI Symbol;Acc:MGI:1860275]
cathepsin J Gene [Source:MGI Symbol;Acc:MGI:1349426]
cathepsin L Gene [Source:MGI Symbol;Acc:MGI:88564]
cathepsin L-like 3 Gene [Source:MGI Symbol;Acc:MGI:1917452]
cathepsin M Gene [Source:MGI Symbol;Acc:MGI:1927229]
cathepsin Q Gene [Source:MGI Symbol;Acc:MGI:2137385]
cathepsin R Gene [Source:MGI Symbol;Acc:MGI:1861723]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa35247 Nonsense Mutation detected in F1 DNA Not yet available
sa31870 Nonsense Available for shipment Available now
sa30959 Nonsense Mutation detected in F1 DNA Not yet available
sa42000 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa35247
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000142362 Nonsense 172 336 4 7
Genomic Location (Zv9):
Chromosome 12 (position 17942703)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 16753877
GRCz11 12 16875751
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCC[A/T]GACCACAGGGCAATCAAGGGTGTAACGGAGGCCTCATGGACCAGGCCTTT
Long Flanking Sequence:
TTTGTAAGACTGTTTTTTTTTTTTTTTCTTACTATCTATTTTTTAGACAAATGAGGAGTTCAGACAGGCAATGAATGGTTATAAGCATGACCCCAACCGGACGTCACAGGGCCCGTTGTTCATGGAACCCAGCTTTTTTGCAGCCCCACAACAGGTTGACTGGAGACAGAGGGGCTATGTTACTCCTGTCAAAGACCAGGTGAGTTTAAAGTAACTGAAAACTGCAAATGTTTTATGCTAAATTAGGACCTATAGTTGCATCTATTACAATTGATCTATTTACAGTTGATCTGGTAAACCCAGTTAAATGTATAAATGGCTATTAAATGTCAGTATGTGTATCTGTAGCTTTACTGTTTTGTGACTCTTCTGTTTTGTGGTTTTAGAAACAATGTGGATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCC[A/T]GACCACAGGGCAATCAAGGGTGTAACGGAGGCCTCATGGACCAGGCCTTTCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATCTTGCAAGGGTAAGAATCATATTGTGACAGTTTCTGAGCAAGGAAAACTCTTTTGAAGACATGGGATTAAACTGCTGTATTTGCAGATTGTGGAAAAATGTCATTTTAGTTTTTTAATCTCTTTGAATGAAGGTCATTAAGTATTTTAAGACTTCAATGTACCACTTTTTTCTTATTTTAACTTTGTGCTTGCAGGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCACCGGATTCGTGGACATCCCCAGAGGTAATGAGCTTGCCCTAATGAATGCTGTTGCTGCTGTGGGTCCTGTATCTGTTGCTATTGACGCATCACATCAATCCCTACAGTTCTATCAGTCTGGTAGGTGCCTGATATCCCTCAACTCTAGTTTTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31870
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000142362 Nonsense 174 336 4 7
Genomic Location (Zv9):
Chromosome 12 (position 17942697)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 16753871
GRCz11 12 16875745
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCA[C/T]AGGGCAATCAAGGGTGTAACGGAGGCCTCATGGACCAGGCCTTTCAGTAT
Long Flanking Sequence:
AGACTGTTTTTTTTTTTTTTTCTTACTATCTATTTTTTAGACAAATGAGGAGTTCAGACAGGCAATGAATGGTTATAAGCATGACCCCAACCGGACGTCACAGGGCCCGTTGTTCATGGAACCCAGCTTTTTTGCAGCCCCACAACAGGTTGACTGGAGACAGAGGGGCTATGTTACTCCTGTCAAAGACCAGGTGAGTTTAAAGTAACTGAAAACTGCAAATGTTTTATGCTAAATTAGGACCTATAGTTGCATCTATTACAATTGATCTATTTACAGTTGATCTGGTAAACCCAGTTAAATGTATAAATGGCTATTAAATGTCAGTATGTGTATCTGTAGCTTTACTGTTTTGTGACTCTTCTGTTTTGTGGTTTTAGAAACAATGTGGATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCA[C/T]AGGGCAATCAAGGGTGTAACGGAGGCCTCATGGACCAGGCCTTTCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATCTTGCAAGGGTAAGAATCATATTGTGACAGTTTCTGAGCAAGGAAAACTCTTTTGAAGACATGGGATTAAACTGCTGTATTTGCAGATTGTGGAAAAATGTCATTTTAGTTTTTTAATCTCTTTGAATGAAGGTCATTAAGTATTTTAAGACTTCAATGTACCACTTTTTTCTTATTTTAACTTTGTGCTTGCAGGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCACCGGATTCGTGGACATCCCCAGAGGTAATGAGCTTGCCCTAATGAATGCTGTTGCTGCTGTGGGTCCTGTATCTGTTGCTATTGACGCATCACATCAATCCCTACAGTTCTATCAGTCTGGTAGGTGCCTGATATCCCTCAACTCTAGTTTTAATTCAATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30959
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000142362 Nonsense 181 336 4 7
ENSDART00000142362 Nonsense 181 336 4 7
Genomic Location (Zv9):
Chromosome 12 (position 17942676)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 16753850
GRCz11 12 16875724
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAAC[G/T]GAGGCCTCATGGACCAGGCCTTTCAGTATGTTAAAGAAAACAAGGGGCTG
Long Flanking Sequence:
CTTACTATCTATTTTTTAGACAAATGAGGAGTTCAGACAGGCAATGAATGGTTATAAGCATGACCCCAACCGGACGTCACAGGGCCCGTTGTTCATGGAACCCAGCTTTTTTGCAGCCCCACAACAGGTTGACTGGAGACAGAGGGGCTATGTTACTCCTGTCAAAGACCAGGTGAGTTTAAAGTAACTGAAAACTGCAAATGTTTTATGCTAAATTAGGACCTATAGTTGCATCTATTACAATTGATCTATTTACAGTTGATCTGGTAAACCCAGTTAAATGTATAAATGGCTATTAAATGTCAGTATGTGTATCTGTAGCTTTACTGTTTTGTGACTCTTCTGTTTTGTGGTTTTAGAAACAATGTGGATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAAC[G/T]GAGGCCTCATGGACCAGGCCTTTCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATCTTGCAAGGGTAAGAATCATATTGTGACAGTTTCTGAGCAAGGAAAACTCTTTTGAAGACATGGGATTAAACTGCTGTATTTGCAGATTGTGGAAAAATGTCATTTTAGTTTTTTAATCTCTTTGAATGAAGGTCATTAAGTATTTTAAGACTTCAATGTACCACTTTTTTCTTATTTTAACTTTGTGCTTGCAGGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCACCGGATTCGTGGACATCCCCAGAGGTAATGAGCTTGCCCTAATGAATGCTGTTGCTGCTGTGGGTCCTGTATCTGTTGCTATTGACGCATCACATCAATCCCTACAGTTCTATCAGTCTGGTAGGTGCCTGATATCCCTCAACTCTAGTTTTAATTCAATATTTGCTAAAATTATTACAAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42000
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000142362 Nonsense 181 336 4 7
ENSDART00000142362 Nonsense 181 336 4 7
Genomic Location (Zv9):
Chromosome 12 (position 17942676)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 16753850
GRCz11 12 16875724
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAAC[G/T]GAGGCCTCATGGACCAGGCCTTTCAGTATGTTAAAGAAAACAAGGGGCTG
Long Flanking Sequence:
CTTACTATCTATTTTTTAGACAAATGAGGAGTTCAGACAGGCAATGAATGGTTATAAGCATGACCCCAACCGGACGTCACAGGGCCCGTTGTTCATGGAACCCAGCTTTTTTGCAGCCCCACAACAGGTTGACTGGAGACAGAGGGGCTATGTTACTCCTGTCAAAGACCAGGTGAGTTTAAAGTAACTGAAAACTGCAAATGTTTTATGCTAAATTAGGACCTATAGTTGCATCTATTACAATTGATCTATTTACAGTTGATCTGGTAAACCCAGTTAAATGTATAAATGGCTATTAAATGTCAGTATGTGTATCTGTAGCTTTACTGTTTTGTGACTCTTCTGTTTTGTGGTTTTAGAAACAATGTGGATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAAC[G/T]GAGGCCTCATGGACCAGGCCTTTCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATCTTGCAAGGGTAAGAATCATATTGTGACAGTTTCTGAGCAAGGAAAACTCTTTTGAAGACATGGGATTAAACTGCTGTATTTGCAGATTGTGGAAAAATGTCATTTTAGTTTTTTAATCTCTTTGAATGAAGGTCATTAAGTATTTTAAGACTTCAATGTACCACTTTTTTCTTATTTTAACTTTGTGCTTGCAGGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCACCGGATTCGTGGACATCCCCAGAGGTAATGAGCTTGCCCTAATGAATGCTGTTGCTGCTGTGGGTCCTGTATCTGTTGCTATTGACGCATCACATCAATCCCTACAGTTCTATCAGTCTGGTAGGTGCCTGATATCCCTCAACTCTAGTTTTAATTCAATATTTGCTAAAATTATTACAAAC
Associated Phenotype:
Not determined