Busch Lab

ZMP

sh2d5

Ensembl ID:
ENSDARG00000014324
ZFIN ID:
ZDB-GENE-050327-67
Description:
SH2 domain containing 5 (sh2d5), mRNA [Source:RefSeq DNA;Acc:NM_001014343]
Human Orthologue:
SH2D5
Human Description:
SH2 domain containing 5 [Source:HGNC Symbol;Acc:28819]
Mouse Orthologue:
Sh2d5
Mouse Description:
SH2 domain containing 5 Gene [Source:MGI Symbol;Acc:MGI:2446215]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa10504 Nonsense Available for shipment Available now
sa41899 Missense Mutation detected in F1 DNA Not yet available
sa35146 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa10504
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000131782 Nonsense 8 410 2 10
ENSDART00000140502 Nonsense 8 149 2 5

The following transcripts of ENSDARG00000014324 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 11 (position 38807790)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 37374809
GRCz11 11 37642014
KASP Assay ID:
2260-4597.1 (used for ordering genotyping assays)
KASP Sequence:
ACTTGTTGACCACCTTTTATATTTATGAACAGTAGAAAAGGCAAACACCA[C/T]AACCAGGTTCAGTTTGGAACATGGGTGAAACAGCTGGAAGAGAGCATGGG
Long Flanking Sequence:
ACTTTACCTTAATATTAGCAACCAACGACCATCAAAGTACCATGAACAATGTTGTACTTTGATAGTCATTGGCTGCTAGTGATGATAGAATTTGCAAAGGATAATTTTCTAAAAGTAGCCTATATTATTAAGAAATATTAAACCAGCATTACCCCAAGAGGTAATTGTACTTTAATATTGGCAACCAACGATCATCAAAGTACAACATTGTTCAAAGTCAAATAAATAGTGCTCATGTTGTTTTGAGGTTATGCTTGAACGTGATTTCAGACCATACAAAGTGCCATGCTAAACAATATAGGGAGAGACTCGAGAGAGCATGTCAAAAGTTGTCACTGAACCAATGTGCGACTATAAAACCTACTTTACCTCAATGATGATTGTTATGATTTCTTTCTTTCTGTCTTACTACTTGTGTGAAGTTTAAATGTTGGATGAGTTTGTGGACAAACTTGTTGACCACCTTTTATATTTATGAACAGTAGAAAAGGCAAACACCA[C/T]AACCAGGTTCAGTTTGGAACATGGGTGAAACAGCTGGAAGAGAGCATGGGACTGTTACAAGATCAGCTGAGGTGAAGATTTGAAAACACTTTAACACATTTCATTAAACATGTACACATAGTTTAAGTTCTTTTATTTATAGAATACATTTAGTAGAGTCACAAGACTGACCAAAGTGCTGTACATAAGACAAAGTAAAATAAAAAGACCGGATATAAGAACAGAAATGAGGCGAGAAACGACTGAAAATGTAGCAGTAGAAAGAAATATTAAGATAATATTAAAACGCCAAGCTTTAAAGGTATGTTTTATGGATTGATTTGAAAATAGTGATGAAGCCATTCTAATCTCTAGGGGCAAGGTGTTCCTTAACCGAAGATCTGCCACAAAAAAGAACTATCCCCTCTATGTTTCATCCTGGACTGAAGAACTAAAAGCAGATTTTGATCACTTGATCTAAGACAGGCGTGTCCAAACTACGGCCCGCGGGCCATCTGCGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41899
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000131782 Missense 292 410 8 10
ENSDART00000140502 None None 149 None 5

The following transcripts of ENSDARG00000014324 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 11 (position 38814969)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 37381988
GRCz11 11 37649193
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTTGGCCGAAACAGAAGAAGCACTGGCTCAAGCTGTGTGGTGTTGGGCT[G/A]GCGTGTCTAGGTCAGTATTAGTGCACAATGACTTTGACGTCTGTTGTTCG
Long Flanking Sequence:
AACTGAGTGCACCACAAGGTGGGATGAGTGTTCATAGAACACTTTCGAGACTGAAAGAGTTCCTTAGGTAATGCACACATCTAGTTAAAAGTAGTTGGTTTAATAAAGTCACGATGGGTTAATTTGGTCATTGGTGGTTGGTGAGTTAAGGAGGTGGTGGGGATTATCAGCTGCCACTATTATCATTATGTCTTATTTATTATGATAAGTCAGTATTATGTGTGCTTCTCAGAATATTACAGAAATTCTTTCCTAAAATAAAACTGAACTTTCGGTCAATCTGAAATAGGATCAGTGCAATGCTTTCTTTTGCCAAATAAAATAAACTTGGTCAAGTAATTTGTGAAGCCAATGAGAACTGAGCTCCTGTGGGAATCTTAAGAATCTTTTGTTTTTGTGAACCAGAAAAGGAACAAGCCACTGCAAAGGCATGCATGTCTCGAGCTCCCAGTTTGGCCGAAACAGAAGAAGCACTGGCTCAAGCTGTGTGGTGTTGGGCT[G/A]GCGTGTCTAGGTCAGTATTAGTGCACAATGACTTTGACGTCTGTTGTTCGGTTAAACATCAGGGTTATAATCTGTTCTTTTTATTTCTCAAGTAGTATATCCTAAGGAGGTCATGTGATGCTATTTTAAATGAGAAGTTCACCCAAAAAATGACAATTCTGTTAATAATTCCTCACCCACTTGTCGTTCAAATCCCCTCAGACATGTTCATTTTTAGAAAACATATCGGGAAGTTTTATAAACTAATTTTGAGAGGATCACAGGCTTCTGATGCATCACAGCTGGTCTCGCATCATCAATCACTAACTAATCAGATGTTTCCAAACGCACATAAATAGTCTACTTTCCTTACCTTAGTCATCTTCGTTTTTTTGAAGTCCCCAAAGTCCCTATTGAACCAGTTGACACTTCTGTGCAGAGTTTTATAAGCAGTGTATCGATCCCTATAATTTGCCAATAACAAGTCGGGGGAGTTCATCGAGCTCTACCTTAGCTCAAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35146
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000131782 Nonsense 297 410 9 10
ENSDART00000140502 None None 149 None 5

The following transcripts of ENSDARG00000014324 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 11 (position 38815655)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 37382674
GRCz11 11 37649879
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTAAAAAAATCTTTGTGTTGAGTATTTGGTGTTTCCATTACAGTGACTG[T/A]AGCTCCTCACTGCTGGCAGATGATGTTTTGGGTGCTTTCCTTCTCTGTCC
Long Flanking Sequence:
GTTCAAATCCCCTCAGACATGTTCATTTTTAGAAAACATATCGGGAAGTTTTATAAACTAATTTTGAGAGGATCACAGGCTTCTGATGCATCACAGCTGGTCTCGCATCATCAATCACTAACTAATCAGATGTTTCCAAACGCACATAAATAGTCTACTTTCCTTACCTTAGTCATCTTCGTTTTTTTGAAGTCCCCAAAGTCCCTATTGAACCAGTTGACACTTCTGTGCAGAGTTTTATAAGCAGTGTATCGATCCCTATAATTTGCCAATAACAAGTCGGGGGAGTTCATCGAGCTCTACCTTAGCTCAAACTCCCCTTTTGTCCTGCTAACGGAAGGGAGCCCTGGGCTCGAGGATCTTATAAGCTCAGGGCTCTCTCAAGGGACAGCATGCAAAACAAGCTTTCATTATCAATCATCGGCTAAGTGCGAACTCTTAAAATCTCTATTTAAAAAAATCTTTGTGTTGAGTATTTGGTGTTTCCATTACAGTGACTG[T/A]AGCTCCTCACTGCTGGCAGATGATGTTTTGGGTGCTTTCCTTCTCTGTCCTCATCCCAAAAAGCCCAATCGTGGATCTCTTATAGTTCGTTTTTCCTCTGGACTGGTAACTTATGCTATTAAGAATTCCAAAGGGAAGTTCCGGCTTGAGGTGAGCAAAGTTTTTACTAAACATTAGTCATTAATTTTCCTTTTCGGTCAGAATGTTTAATCTAGTCAATGTTTAATCTTCATTTACAGAAGTGCCACACTGACTTTGAAAGCCTTGCTGCTTTAATGGAGCACTACACAGAGTTCGGTGACGAGCTGGAATGTTCTCTGAGCTGCGCACGCGTCAACCACTGTTACGACTGGGAGGAGATGGTGAATAAGGGTTCACGTTTACTGCAGGACAACAAAAAAGGCACTTTTAAATGCCGAAGTTGGGTTTGAATCATGTATTTCTTTTTAGATCTCATTTTTATGCTATATTTTACTTAGTTTTAGGTATTTGTGGAGCTG
Associated Phenotype:
Not determined