Busch Lab

ZMP

ppfia4

Ensembl ID:
ENSDARG00000053205
ZFIN ID:
ZDB-GENE-070720-14
Description:
PTPRF interacting protein alpha 2 [Source:RefSeq peptide;Acc:NP_001093621]
Human Orthologue:
PPFIA4
Human Description:
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), al
Mouse Orthologue:
Ppfia4
Mouse Description:
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), al

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa41821 Nonsense Mutation detected in F1 DNA Not yet available
sa41822 Nonsense Mutation detected in F1 DNA Not yet available
sa35073 Essential Splice Site Available for shipment Available now
sa41823 Nonsense Mutation detected in F1 DNA Not yet available
sa27773 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa1878 Essential Splice Site Available for shipment Available now
sa11854 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa41821
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090182 Nonsense 153 1174 4 29
ENSDART00000112567 Nonsense 190 1211 4 29
Genomic Location (Zv9):
Chromosome 11 (position 23331027)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 22337258
GRCz11 11 22497826
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCGTGAAAGGTTGCGTGTGGCTCTTGAAAGGGTGACTACATTAGAAGGA[C/T]AGCTGTCAGCCGCCACTCAGGAGGTACAGCTCTATTGTGCTTGCGTGTGT
Long Flanking Sequence:
CAGTAACAATATAATTACTATGACTGTTTAATTTAAGTAATTATCTATAGTATGCTTCCAAACACTATAGTATTTACTATAGTATTTTTCATGTAACATAATTATACAGCATGTACCGCTTTGATTACAGGCAAATGCCCAACATATGTGGTTGTTTTCTATTTATATCTCCTTTAAAATATGGTATAAATCTAAAAAAAAAAAAAAAAACAGACTTTCCTCTATGTCTCCCATTCATTTTTTACTTCCTGTCCTCTATCTGAATTTTGTGCGCCACCAGAACCACGTGATTAAAAACAACCTATAAGTCACTTTTTACATGTTTCTAGATGATAATAAACATGACATGTTCAGGAAAATGTAGTTGTTGAAACAGAATGAAAACCAACGTAGCTTAGTTGGCACGTGTTCACTTGACCATTAAAGTCTCTTGTTTCTCATTCGCACAGGTGCGTGAAAGGTTGCGTGTGGCTCTTGAAAGGGTGACTACATTAGAAGGA[C/T]AGCTGTCAGCCGCCACTCAGGAGGTACAGCTCTATTGTGCTTGCGTGTGTGTGTGTGTGTGTGTGTGTGTTTAGGCATGCACATGCACTGGTGTGGATTTGCTGATCTCATTAACATCTGTCCAGTGAGCACCTGCCCCCTGCTGTCAACCCATGCAGGAAATGCCCGCTGTCTGTTTCCATCACTCACACGTCACTGAGAGTTCAAGCAAAGCAAATGCACTTGACATACCATAGATTTATGCTGATACGAAAAAAATGCATTGACAACACAATTACTCACCGCACTCCTTTTCATTTTGTTTGTGTAGCTTGTGAGAGTTAGTATATGTGTTTAATTGTAATCATTGTTGAAAGCATTGTCCTAAAAACAACATTGTCCTAAAATAACTCCTTAAACCACTCAACACAGACTTAATCATCTTATATTATTGGAATGTTTGGCTAAAGATGAAAGAAAATGCTTGGCCTGTTTAACTAATGGTTTTTCACATGCATAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41822
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090182 Nonsense 459 1174 12 29
ENSDART00000112567 Nonsense 496 1211 12 29
Genomic Location (Zv9):
Chromosome 11 (position 23363777)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 22370008
GRCz11 11 22530576
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAGTGATTTCTGTCTATGTAGGAGAGACTCATTGGGGAGATTGAGAAGT[T/A]AAGGGCTGAACTCGATCATCTGAAGCGCAGAAGTGGAGCATTTGGAGATG
Long Flanking Sequence:
CTACAAATTGTAATTGCAGAGAATGTTCAAGTATTTTTGTATATAAATTTATAATTATATATAAATAATATTAATAATGAACAATATAGAATATTGGTATAAACTAAATATGAATTAATATTATAAATAATATTTATATGAAATTTTGCTATTAATAATTGTCTCATTTAAATATATGCATATTTCTTTCAGGACACTGATGAATAGAGCTTTTGAAAGATCTGTATCCAATTTAAATAACAATCTTATTTAACATTATTTATGTTTTGCTGATAAAAAAAAAAAAAACATTGTATTAATAAAAATGGAGGGTAAACTTTGGTATTGTGTTTTTAAGAATGTGTACCTTAAAAATAGTAATCTTAGTTCATAGAAGTTCATAAGAGTGACATCCCTACTGTAACAATTCTAGTCATTAAAATGTTAATAATTTAGTATTGTTCAGCTAATTGAGTGATTTCTGTCTATGTAGGAGAGACTCATTGGGGAGATTGAGAAGT[T/A]AAGGGCTGAACTCGATCATCTGAAGCGCAGAAGTGGAGCATTTGGAGATGGGACACATCCTAGGTGACTAGATCCTGATTTAAAGCATGGCTTCAGTTTTATTACATAATGTAAATAATAGGGATGTACAATCCCTATTATTTAGGGATAATAGGGATGTACAATAATAGGGATTTTTATTTTTTTATTAAAAAATAAAAGCGATAATTGGACTTGACTAAATTTGTTGTTTTTAAATTGATTAGTTGACTTTAAAAAGTGAGTAAACCTGATCAATTAAAATTAAGTAAATAAACTATGTGCATAAATATAATTTTTATTACAAGTTACAACTGGTTCACTCAGTTGCTGGTGAAATTATATATTGCAATTTAGATAAACTCTAACTGAAAATGTATTTATATTGAAAAATGAACAGAAAAAGAAAACATTGTAATGTCAGTTGCCATTTCCATTATCCTGAAGCCCTAGTAAATACGCTGAAATATGATTCCAGTTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35073
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090182 Essential Splice Site 524 1174 13 29
ENSDART00000112567 Essential Splice Site 561 1211 13 29
Genomic Location (Zv9):
Chromosome 11 (position 23364476)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 22370707
GRCz11 11 22531275
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACGTGCTCAGAAAGGTCGAATGGTGGCACTCAGGGATGAACCAACCAAG[G/T]TGAAAATGTCACACATACAGCACTTCTCCATCCATCACCGTCTTATGTCT
Long Flanking Sequence:
AAGCGATAATTGGACTTGACTAAATTTGTTGTTTTTAAATTGATTAGTTGACTTTAAAAAGTGAGTAAACCTGATCAATTAAAATTAAGTAAATAAACTATGTGCATAAATATAATTTTTATTACAAGTTACAACTGGTTCACTCAGTTGCTGGTGAAATTATATATTGCAATTTAGATAAACTCTAACTGAAAATGTATTTATATTGAAAAATGAACAGAAAAAGAAAACATTGTAATGTCAGTTGCCATTTCCATTATCCTGAAGCCCTAGTAAATACGCTGAAATATGATTCCAGTTGAAAGTGAGACTGCTGTAGAAGTACTAAGTGAAGTGTGTGAGCCTCTGCCGCTGTGTATTGTGTCAGGTCTCATCTTGGCAGTGCCACAGACCTGCGGTTCTCCGTGGTGGAGGGTCAGGGCGATCACTACTCCTCCACAGGGGTCATACGACGTGCTCAGAAAGGTCGAATGGTGGCACTCAGGGATGAACCAACCAAG[G/T]TGAAAATGTCACACATACAGCACTTCTCCATCCATCACCGTCTTATGTCTAGTCTACACCTGCTATTAATCCGATTACAAGTGGATAACACTAAACACTAAATCTAAAACGTTTTAAGCTTGTCCACTACAAGGGACATGTGAAAATGCATTTCAGGGCTCTATAGTAGGGCTATTTTAGTTCTTTTCTACTGGATTTCACCTAAACCTTTATTAATTTTTACATTTACTCATGAATTGGATAAAATTAAAATTTGCTGTATTCTATGAGTGTGTGTGTGTGTGTGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGAGTGAGTGTATGGGTGTTTCCCAGTACTGGGTTGCAGCTGAAAAAGCATCTGCTGTGTAAAAACATATGGGAAAAGTTGGTGGTTCATTCCGCTGTGGTGACCCCTGATAAATAAGGGACTAAGCAGAAGCAAAATGAATGACTAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41823
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090182 Nonsense 591 1174 14 29
ENSDART00000112567 Nonsense 628 1211 14 29
Genomic Location (Zv9):
Chromosome 11 (position 23368715)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 22374946
GRCz11 11 22535514
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCCCAGCGGGCACTCAGACGCCCAGACGCTTGCCCTCATGCTCCAAGAA[C/T]AGCTGGATGCCATCAATGAGGAGATCAGGTTGGGAATAATAATATGGAAA
Long Flanking Sequence:
CCATCTATTAGACATCTTTTAAACACAAAAATGCTTTCTAGGTATGAGCACTGGTATAACTGGTGCATTTCAGGATCAAGTAGCCTTTTTCTAAACTAATAATCAAATAATGATTTTTTTCTCTCTTTTCTTGATTTCTGCCCCATTGGATGTGTTCACTGTAAGTTAAGTTCCAGGTTTTCTCATTTTCAACAAAACATGTTCATAGCATAATCATGTGTTACTGAAACACTCAAATCTGGAAGTCTGATTAAAAACCCTTTAAATGTTGATTTGTGCTTTAATTCATCTCTTCGTCCCAGATCCTTCCAATGGTGGAGCAGGACTGGGATCGCTCTCAACCATCCAGCTTGCGGGCCAGCCGTACTCACCTGATGGGAAGCGACACTGAGCTCTCTGACTTGGACGATGAAGACCGGGAGACCATATTCAGCTCAGCCGATATACTGTCCCCCAGCGGGCACTCAGACGCCCAGACGCTTGCCCTCATGCTCCAAGAA[C/T]AGCTGGATGCCATCAATGAGGAGATCAGGTTGGGAATAATAATATGGAAAAATATTTGCCACTTTTTTATTTTGAAGTTTTGTTCAACTTTTTTTACCTACTATGTTTGTAAAAGAGTATGAGATTTTGGATGCACTTGTTTTTGCCAAATAATTTTCATGTTAATTTGTTTTGTTTAACTTGTTTTTATCATTATAAGCACAAGCCTCATCTTAAAGGGAAAGGTGGAGGCTTTGGCATAATAATTAGTAATATTTTAGTGTCACTCACCCACTAGTGTAATTCATTTGAAGTAATAGTGTTGTATATTTCAGTAACCGATCTAAAGCTAGACATACTCTGTCTAACAGTAACCAGACAATTACATGACCCTAAACGAGTCTTCATCTAAAATATGTCATTTTGTCTTTGGAAAGTACAGACATATACAGAAAGAGTACAAACATGATGTACTCTAATTCTTTTTTCTTATAGTTTAACAACCCAGAGTCATTTATACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa27773
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090182 Essential Splice Site 690 1174 16 29
ENSDART00000112567 Essential Splice Site 727 1211 16 29
Genomic Location (Zv9):
Chromosome 11 (position 23382574)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 22388805
GRCz11 11 22549373
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTTCAGCCTAGTGATTTAAGGAAACACCGCAGGAGAGTGGCTGTAAGTG[T/C]GGCTTCATCTCTAAATGTCTTCACTGAACAACGGTTTATTTGTACTATTT
Long Flanking Sequence:
CACAGTTACAACCGTTTTTGCATCCTTGTTAGAACTCAGACTGCTAGCGATCAGAAATTTATGTTAGTAATGCTGAACGCATTCTATGTGGTACAGGAGACACAGACGAGATTGATTGACAATGGTCTACAGCCAATCAGGATGCAGAACACAATCGGCTTAAAAAAAGCATGTCAAATTTAACTAAAAAAATCAGAAGCTGTGAAAGGTGAACCGCCTTATAGAGAGGGACTACTGTAATGGAAACCGGTAGCCATCGAATTCCATAGTAGGAAACAAAATGGTATGGAAGTCAGTTGCTACCAGCTTTTAGCTCGTATCAAAATATCTTTTAGAAATAAAATCAGATTTGGAACAAGTAAAGGGTTTTTAAATCTCCTTTTTCTAACACTGACAACACATAATCATCTGTCATCCTGCATTTTTCCTTGTCTTTTTCTTCCTGCTAACCCTTCAGCCTAGTGATTTAAGGAAACACCGCAGGAGAGTGGCTGTAAGTG[T/C]GGCTTCATCTCTAAATGTCTTCACTGAACAACGGTTTATTTGTACTATTTGACCTTACGACAGATACATGAGTGACAGGCCAGACAGCCAATTACATTGCTGCATGTTGAGGTCTTGCTCCTGCTCCTGTTTTTATCCATTGAGGTTTAAAGGTTGCTCAAGCTTTACTGACCTGCACACATTTAAACATCCATTTTATTTTAGCCGTGGAAGAAAAGTTGTTGGTATGAAACATATAATTCCAATTACAAGAGTGGCTATTTAATAAAGTTTGATCAGCATAAATGAGTACACAGATCTCTGTTTGAAACTATTGTTTTCTACAGGATGCTTTACGACAGTGTTTCTTAACCACGTTTCTGGAGGACTCCTTTGTCTGTCACAACCATTACAAACCTTTTAATCTGTGCTGATTAGCTGATGATCTGAATCAGGTGTGTTTGGTTAAGGGCTGTTTCTCAATTCCAAGAACGCAGAGAACAGACTTGAGTTCTCGTGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1878
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090182 Essential Splice Site 984 1174 25 29
ENSDART00000112567 Essential Splice Site 1021 1211 25 29
Genomic Location (Zv9):
Chromosome 11 (position 23406028)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 22412259
GRCz11 11 22572827
KASP Assay ID:
554-1868.1 (used for ordering genotyping assays)
KASP Sequence:
ACACACACACTTTAAACATGACCTACAATACTACATTCATTATGTCTTAC[A/T]GGGCTAGTTTGCACTATGGCATCATGTGCTTGAAAAGGCTAAACTATGAC
Long Flanking Sequence:
TCCAAATGCCTTCTCTGAATGTGCTCGTTAGCATTCTGTATGGCTTTTGTGGCTAAAATTACCATTGACTGTATTCACTGATGACAGTTTTATCCTGAAACTTATCTTTTCTCTAAAAACTAGAGAATTGTGCTAAAAAGTTATTAATATAATGTTTATTAGTTATTACTGGCATTTTTGTTATGTGGAATTCAATTGTTTTATTGTTACCAGAGTGCCAGATTGGAGTGTAAAGGCTCTGTTCTCTTCTTGAAAGCAGCAGCTCATTTGCATTTAAAGGCACACATACAACAACTATGCTAATTTGCGCTCACACAAGTAGGGTCAAACTTGACCTGCAATAATAAATGATCTTAAGCTGAAATTCACAAATACATTCTGGGGTGCAGCAGAGATTTATTTACATCTTATTAAAAGTGTCAATACTGTATGTTCTTTAAAAAAAAAAACACACACACACTTTAAACATGACCTACAATACTACATTCATTATGTCTTAC[A/T]GGGCTAGTTTGCACTATGGCATCATGTGCTTGAAAAGGCTAAACTATGACCGGAAGGAGCTGGAGCGAAGGAGAGAGGATTTCCAGCATGATATCAAAGGTATGAATAATTTGTGAAGGAAAGAGCACTATCTAGTGGTCATTGCTGTAATTGACAGGTTGCTGACAAGAATGTGTGAGGACTGAGGAGAGGTCAACAGCTGAGCTTTTTAGTGTCAAATCCATTTAAAGGGACGGCGCCCGGCTGAACTTCAGCATCACACATGAACTTGACACAGCTGTCACAGCTTTTTAAAATCTTTCATCTTTAGCGCTAAAGACACACGCACCAACTGCTTGACACACACACACACACACTTAAGCAAATTACACACAGGATTGTACAAACAGAAAGCAGAAGAGCCAGCTGTGCAAAAGGATCACACTGCGCTTCTAATGTTACCTAAATACTGATATTTACAGTACTGTTGTAAACACAACCAGTGTTTGCTGCATTAATGT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa11854
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090182 Nonsense 999 1174 25 29
ENSDART00000112567 Nonsense 1036 1211 25 29
Genomic Location (Zv9):
Chromosome 11 (position 23406075)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 22412306
GRCz11 11 22572874
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACWGGGCTAGTTTGCACTATGGCATCATGTGCTTGAAAAGGCTAAACTA[T/G]GACCGGAAGGAGCTGGAGCGAAGGAGAGAGGATTTCCAGCATGATATCAA
Long Flanking Sequence:
TGTGGCTAAAATTACCATTGACTGTATTCACTGATGACAGTTTTATCCTGAAACTTATCTTTTCTCTAAAAACTAGAGAATTGTGCTAAAAAGTTATTAATATAATGTTTATTAGTTATTACTGGCATTTTTGTTATGTGGAATTCAATTGTTTTATTGTTACCAGAGTGCCAGATTGGAGTGTAAAGGCTCTGTTCTCTTCTTGAAAGCAGCAGCTCATTTGCATTTAAAGGCACACATACAACAACTATGCTAATTTGCGCTCACACAAGTAGGGTCAAACTTGACCTGCAATAATAAATGATCTTAAGCTGAAATTCACAAATACATTCTGGGGTGCAGCAGAGATTTATTTACATCTTATTAAAAGTGTCAATACTGTATGTTCTTTAAAAAAAAAAACACACACACACTTTAAACATGACCTACAATACTACATTCATTATGTCTTACAGGGCTAGTTTGCACTATGGCATCATGTGCTTGAAAAGGCTAAACTA[T/G]GACCGGAAGGAGCTGGAGCGAAGGAGAGAGGATTTCCAGCATGATATCAAAGGTATGAATAATTTGTGAAGGAAAGAGCACTATCTAGTGGTCATTGCTGTAATTGACAGGTTGCTGACAAGAATGTGTGAGGACTGAGGAGAGGTCAACAGCTGAGCTTTTTAGTGTCAAATCCATTTAAAGGGACGGCGCCCGGCTGAACTTCAGCATCACACATGAACTTGACACAGCTGTCACAGCTTTTTAAAATCTTTCATCTTTAGCGCTAAAGACACACGCACCAACTGCTTGACACACACACACACACACTTAAGCAAATTACACACAGGATTGTACAAACAGAAAGCAGAAGAGCCAGCTGTGCAAAAGGATCACACTGCGCTTCTAATGTTACCTAAATACTGATATTTACAGTACTGTTGTAAACACAACCAGTGTTTGCTGCATTAATGTTTACTGCCTGGGATAGAGGTGGTCTGAGCAAAATCATTTACAGTACA
Associated Phenotype:
Not determined