ZMP

si:dkey-169a9.2

Ensembl ID:

ENSDARG00000073665

ZFIN ID:

ZDB-GENE-090311-50

Human Orthologue:

RASA1

Human Description:

RAS p21 protein activator (GTPase activating protein) 1 [Source:HGNC Symbol;Acc:9871]

Mouse Orthologue:

Rasa1

Mouse Description:

RAS p21 protein activator 1 Gene [Source:MGI Symbol;Acc:MGI:97860]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa41739	Nonsense	Mutation detected in F1 DNA	Not yet available
sa34987	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa41739

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108954	Nonsense	623	1032	14	25
ENSDART00000132486	Nonsense	461	652	13	17
ENSDART00000141543	None	None	209	None	7
ENSDART00000148205	None	None	95	None	2

The following transcripts of ENSDARG00000073665 do not overlap with this mutation:

ENSDART00000141685

Genomic Location (Zv9):

Chromosome 10 (position 44909437)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	43603025
GRCz11	10	43431405

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGCATTCAGGTGGCAAAAACCCACCCGCGGGAAGGCCAGAACCCCGTGTG[G/A]ACGGAGGAGTTCATTTTCGAGTAAACCAATGTTCATACCGATTTGATGTG

Long Flanking Sequence:

TCTAGGCTAGTTTTTAAACAGCAGGTGGTGATCCAGGCTCGTTTTTAAACAGCAGACAACGCTCTAGGCTAGTTTTTAAACAGCAGAGGGTGCGCTAGGCTAGTTTTTTTAAACAGCAGATGTCACTCTAGGCTAGTTTTTAAACGACAGATGGTGATCTAGGCTATTTCAACAGCAAATGGCGATCTAGACTAGTTTTTTTTTAATACAGGAGTCTAGGCTATTTTTAAACAGCAGCTGGTGTTCTAGGCTAGTTTTTAATAGAGTCTCAAACAAACGCTTGTGTCAGGTAAACTCATTTTCTTTTCATCACGTTTATTATTACTTACTGCAGAGTTACTCCACCAGTGGTTCTCTTTACAGGTCAGCAGTTTATTTCTGAACGTCGAAGAGGCTCACAAACTTCCCAGTAAACACTTCACAAACGCCTACTGCAACATTTACCTAAACAGCATTCAGGTGGCAAAAACCCACCCGCGGGAAGGCCAGAACCCCGTGTG[G/A]ACGGAGGAGTTCATTTTCGAGTAAACCAATGTTCATACCGATTTGATGTGAATTTTGTGATATTGTGCATCTTTATGAACGTGTCTATATACTCCTGCAGTGACCTGTCCAGCGAGATCAACAGGTTTGAGATCAGCCTGAGCAACAAGACCAAGAAAAGCAAAGAGAATGATATTTGTACGTTCTTTCATTTTGCTTCACTATTAAATAATCTGATTTTTATCAGCAGATGGCGCTCTAGGCTAGTTTTTAAACAGTAGACAGTGCACTGGGCTAGTTTTTAACAGCAGATAGTGCTTTAGGCTAGTTTTTACCAGCAGATGGCGCTTTAGGCTAGTTTTTAAACAGTAGACGGTGCTCTAGGCTAGTTTTTAACAGCAGATGGCGCTCTAGGATAGTTTTTAACAGCAGATGGTGCTCTAGGCTAGTTTTTAACAGCAGACGGCACTCTAGGCTAGTTTTTAAATAGTAGATGGTGCTCTAGGCTAATTTTCAACAAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa34987

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108954	Nonsense	978	1032	24	25
ENSDART00000132486	None	None	652	None	17
ENSDART00000141543	Nonsense	156	209	6	7
ENSDART00000148205	None	None	95	None	2

The following transcripts of ENSDARG00000073665 do not overlap with this mutation:

ENSDART00000141685

Genomic Location (Zv9):

Chromosome 10 (position 44921711)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	43615299
GRCz11	10	43443679

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGGTGTCTGAGCTGCCAGAGCCCACAGAGCACTTTAACACAGATGTGGCT[C/T]GAGATCTGGCTGCTCTGCATCAGCTCTGCGTCACACATCTGGATGAGCTG

Long Flanking Sequence:

ATGTGGTAAAATGATTGTAAAATACAGAATAATGTGGTGAAATGATACAGAAATACAGATTAATGTGGTAAAATAATAGTAAAATACAGAATAGTGTGGTGAAATGATACAGAAATAATACTGATGATCTTCAAATTGGGCGCCAGATCCCCATAATCCACATCTATTCATAACATTCAGTCTTTTCTTCAAGTCTGTTGAGAAATCTTGCTGTAATATTGATGTTGTGAGTTTAATGTGTGTGTAAGAGGTTAAGGAAATGCAGAATATTAGGGTAAAATGATACAGAAATAACACAAATGATCCTCCAGAGGGCGCCAGATCCCTTTAATCGACACCCATCAGCAGCATTTTTACAGTCTTTTCAAAAACACAGTCTATTCTTTATTTCTGTGCTGAAAGCGTGCAGTAATATTGATGTTGTGTGTTAAATGTGTGTGTGTGTTCAGAAGGTGTCTGAGCTGCCAGAGCCCACAGAGCACTTTAACACAGATGTGGCT[C/T]GAGATCTGGCTGCTCTGCATCAGCTCTGCGTCACACATCTGGATGAGCTGCGGACGCTGAGCAACGACAGAGGAGCACAGCAGGTACAGCATTAATAAGTGAAAATAAAGGGGAAAATCTGAAATGTCATTGCTATTTAAAACAATAAGTAAATAAATAAAAGTATATAAAAATAAAAAAGTAAATAAATAAAAGTAATTATATATATATATATATATAAATAAATAAAAGAAATAAATAAAAGTAAGTATATATAAAAGAAAAATAAGTGAATAAATAAAAGTAAGTATATATAAATAAAAAAAATTAATAAATAAATAAAAATAAGTATTTAAAAATAAAACAATAAATAAAATTAAGTATGTATAAAAGAAAAAATAAGTGAATAAATAAAAGTATATAAAAATAAAAAAGTAAATGAATAAAAGTATATATAAATAAAAAATAAGTAAATAAATAAAAAGAAGTACATAAAAATAAAACAAGTAAATAAATAAAAG

Associated Phenotype:

Not determined