ZMP
tbr1b
Ensembl ID:
ZFIN IDs:
Description:
T-box brain protein 1 [Source:RefSeq peptide;Acc:NP_001108562]
Human Orthologue:
TBR1
Human Description:
T-box, brain, 1 [Source:HGNC Symbol;Acc:11590]
Mouse Orthologue:
Tbr1
Mouse Description:
T-box brain gene 1 Gene [Source:MGI Symbol;Acc:MGI:107404]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa10845 | Nonsense | Available for shipment | Available now |
| sa41554 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa34772 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa10845
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006612 | Nonsense | 173 | 676 | 1 | 6 |
| ENSDART00000125742 | None | None | 437 | None | 7 |
Genomic Location (Zv9):
Chromosome 9 (position 52782324)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 9 | 51975685 |
| GRCz11 | 9 | 51435859 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTATTGAGCAACTCTTCTCCGCAAGGTYACGCGACCGCCGGGTACCCGTA[C/A]GCGCAACAGTATGGACACGCGTACCAGGGCACGGCTTTCTACCAGTTTTC
Long Flanking Sequence:
ATCTCGCCAGCTCTCGCGCGCTCCAAGAAATGTATGATTGTGGGCAGTGGCTACCCAAACGCACAAGCGTCTGAGCTCGCCTTGCAGGACTACCCTATTATATCAATCGGCGACAACCTGGAGAGAAGTTCACCTCTGAAAAAAAACTCCGCTGGGATGACGAATCAGTCAGAGGCAGACAATTTCGCCGACTCGAAGGACTCATCAGGGGACGTCCAGCGAGGCAAACTCTCTCCTGATCTTGACGGAGTCGCCGACAGTCGTCACACTTTCGATGGATCTGCAGGAGAAAGGTATCTCCTGTCTCAGTCCAGTCAAGTTCAGCCGAGTCCTACCACCATGTTTCCCTACCCGAGTCAGCATGGACCGACGCACCCGGCTTTCTCCATCGCCAGCCCGAGCCGCTACATGGCGCACCACCCGGTCATCACGAACGGAGCCTACAACAGCCTATTGAGCAACTCTTCTCCGCAAGGTTACGCGACCGCCGGGTACCCGTA[C/A]GCGCAACAGTATGGACACGCGTACCAGGGCACGGCTTTCTACCAGTTTTCCTCCGCGCAAGCAGGACTCGTGCCCGGCAAAGCGCAGGTTTACCTCTGCAACAGGGCCCTGTGGCTTAAATTCCACAGGCATCAAACGGAGATGATTATTACCAAGCAGGGACGGTAGGTGTTTTTGCTGTTACGGTTATAAATGAGTGTTTGCCAAACTATTGTTTCCACAAATGGATGTTTTCGTTTGGCGAATATCAATAGGGACATATTAAGACACATATAAAACATATATCTTTTTCTTCCGACAAATACAAAGCTGTTTTTTTATTTTTTTTATTTCAGTTTTCATTTTCCGGGAACAAAATATTAACGATTTAATAAAAATAAATTAAATGAACGTTTTCATAATAATAATAATAGTAATAATAATAATAATAATAATAATAATAATTATTATTATTATTATTATCATTATTTATTGTTCTTATTGGTTAATTTAATTTTCTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa41554
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006612 | Essential Splice Site | 373 | 676 | 4 | 6 |
| ENSDART00000125742 | Essential Splice Site | 135 | 437 | 3 | 7 |
| ENSDART00000006612 | Essential Splice Site | 373 | 676 | 4 | 6 |
| ENSDART00000125742 | Essential Splice Site | 135 | 437 | 3 | 7 |
Genomic Location (Zv9):
Chromosome 9 (position 52780402)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 9 | 51973763 |
| GRCz11 | 9 | 51433937 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTCCCCGAGACGCAGTTCATTGCTGTCACCGCATATCAAAACACTGAT[G/A]TAAGAGAAAGAGAATTGTGTTGATAATTCGGTTGATTTGTGGAATATTAA
Long Flanking Sequence:
CGTATGTAAATAAAAGCAACTGTTCAAAATAATCAGTACAATTAAACGAAATAATATCTTTATTATTAATGTAAATCTATATTAGGAAAAGGTAAACAAAAACTTGATGTTTATTAAACGTTGCATTCGTTTTTGTACGCATGACATGTACCAGCTTAAATTATTTAACATATTAAATCTAATCCAGTTAATTTGTTGCTATGAATTATTGGTTTACATTTATGCGCTTCAAATCGTGAAGGAGCTAATTTGCTTCAATGTGTTTGAATGGAAGCACGCGAGCGTAAAGACGCGTGAAGGGATGTTTTCTGACTCTCGTTTTTTCGCTTGAATTCCTGCAGATGGTCGTCCTGCAGTCGCTGCATAAATACCAGCCTCGACTGCATGTGGTGCAGGTGAACGAGGACGGAACGGAGGACACGAGCCAACCCGGGCGCGTGCAGACCTTCACTTTCCCCGAGACGCAGTTCATTGCTGTCACCGCATATCAAAACACTGAT[G/A]TAAGAGAAAGAGAATTGTGTTGATAATTCGGTTGATTTGTGGAATATTAAAGTGTTTTTAATGGTTTGAATTGTGTTGTTTACAGATCACGCAGCTAAAAATCGACCACAACCCATTCGCGAAAGGATTCCGTGACAATTATGACACGTAAGTTTTGATTTTATCTTGTTGAAATTACATTTAGATGCTTTCTAATTTGTCTGAACAAACATTATTAGCCTAAATAAATAAATCAAATATTTAATATTACCGACTTGAGTGAAACTAATAGGTTCGGATGAAATTAATAGTTTTTTGGGGCTTAACCTTAATAGATATCCTGCATTTGTGGATGATAATTTATTTGTCCTGCTGAATATTTTGGCAAAACGTAATTATTCTATGAAGAATAATAATGCGCGTGCATTTAATTTGGTAATCAGCGCGTCTGGTTTTCATAAGTCTGTCAAATGACAGAGAAATGAATTTATTGACAGAAATCCCATTGGCCAGTGTATTAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34772
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006612 | Essential Splice Site | 373 | 676 | 4 | 6 |
| ENSDART00000125742 | Essential Splice Site | 135 | 437 | 3 | 7 |
| ENSDART00000006612 | Essential Splice Site | 373 | 676 | 4 | 6 |
| ENSDART00000125742 | Essential Splice Site | 135 | 437 | 3 | 7 |
Genomic Location (Zv9):
Chromosome 9 (position 52780402)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 9 | 51973763 |
| GRCz11 | 9 | 51433937 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTCCCCGAGACGCAGTTCATTGCTGTCACCGCATATCAAAACACTGAT[G/A]TAAGAGAAAGAGAATTGTGTTGATAATTCGGTTGATTTGTGGAATATTAA
Long Flanking Sequence:
CGTATGTAAATAAAAGCAACTGTTCAAAATAATCAGTACAATTAAACGAAATAATATCTTTATTATTAATGTAAATCTATATTAGGAAAAGGTAAACAAAAACTTGATGTTTATTAAACGTTGCATTCGTTTTTGTACGCATGACATGTACCAGCTTAAATTATTTAACATATTAAATCTAATCCAGTTAATTTGTTGCTATGAATTATTGGTTTACATTTATGCGCTTCAAATCGTGAAGGAGCTAATTTGCTTCAATGTGTTTGAATGGAAGCACGCGAGCGTAAAGACGCGTGAAGGGATGTTTTCTGACTCTCGTTTTTTCGCTTGAATTCCTGCAGATGGTCGTCCTGCAGTCGCTGCATAAATACCAGCCTCGACTGCATGTGGTGCAGGTGAACGAGGACGGAACGGAGGACACGAGCCAACCCGGGCGCGTGCAGACCTTCACTTTCCCCGAGACGCAGTTCATTGCTGTCACCGCATATCAAAACACTGAT[G/T]TAAGAGAAAGAGAATTGTGTTGATAATTCGGTTGATTTGTGGAATATTAAAGTGTTTTTAATGGTTTGAATTGTGTTGTTTACAGATCACGCAGCTAAAAATCGACCACAACCCATTCGCGAAAGGATTCCGTGACAATTATGACACGTAAGTTTTGATTTTATCTTGTTGAAATTACATTTAGATGCTTTCTAATTTGTCTGAACAAACATTATTAGCCTAAATAAATAAATCAAATATTTAATATTACCGACTTGAGTGAAACTAATAGGTTCGGATGAAATTAATAGTTTTTTGGGGCTTAACCTTAATAGATATCCTGCATTTGTGGATGATAATTTATTTGTCCTGCTGAATATTTTGGCAAAACGTAATTATTCTATGAAGAATAATAATGCGCGTGCATTTAATTTGGTAATCAGCGCGTCTGGTTTTCATAAGTCTGTCAAATGACAGAGAAATGAATTTATTGACAGAAATCCCATTGGCCAGTGTATTAA
Associated Phenotype:
Not determined