Busch Lab

ZMP

wdr3

Ensembl ID:
ENSDARG00000011079
ZFIN ID:
ZDB-GENE-030131-9830
Description:
WD repeat-containing protein 3 [Source:RefSeq peptide;Acc:NP_942574]
Human Orthologue:
WDR3
Human Description:
WD repeat domain 3 [Source:HGNC Symbol;Acc:12755]
Mouse Orthologue:
Wdr3
Mouse Description:
WD repeat domain 3 Gene [Source:MGI Symbol;Acc:MGI:2443143]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa41397 Nonsense Mutation detected in F1 DNA Not yet available
sa30916 Nonsense Mutation detected in F1 DNA Not yet available
sa34610 Essential Splice Site, Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa41397
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003648 Nonsense 316 938 9 27
ENSDART00000147892 None None 61 None 4
ENSDART00000003648 Nonsense 316 938 9 27
ENSDART00000147892 None None 61 None 4

The following transcripts of ENSDARG00000011079 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 21893057)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 21048843
GRCz11 9 20859712
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGTTTTTACTGTACTATCAGAGGAGGAAATCCAAAGAAAAATGGACAGA[A/T]AACTGAAGAAAGCCAAGAAAAAAGCCAAGTATGTTAGACCCTTGTTTTGA
Long Flanking Sequence:
CTCAGCTGTAAGAAAGCCGGGTCTATTCTGAGAGAAGCCAGAGACAGAGTTGTATCATTGGTTACAGATGCCAAAGCTAAAGTTCTAGCCTGTCATGTAAGTATGAGTTATATATTCAGCTTTGTTAGCTTTTTCTTACCAAACACAATTCCACAAAGAGGAATTTAAAAGGATAGTTTACACAAAAATGTAAATTCCTACTCACCCTTCACTTGTCACAATTCTGTTGAGTTTCTTTCTTCTGTTGAACCCAAAGGAAGCTATACTGAAGAATTTTGGCCATTGAATGGCTTTTGGTTTCCAACATTCTTCAGAATATCTTGTTTAATGCTCATCATAAAAAAGAAATTCAGCCAATAATGTGGAGATGTTAATTTTTGGGTAAACCTCCTTTAATGTATATCAAGAAATGTATTTTAAAACCTTTACAGGGCCTGGATGCTACCCTTGAAGTTTTTACTGTACTATCAGAGGAGGAAATCCAAAGAAAAATGGACAGA[A/T]AACTGAAGAAAGCCAAGAAAAAAGCCAAGTATGTTAGACCCTTGTTTTGATACCAATGATGAAAGTATGGTATCCTGATTGACTGTTATATTGTGCAGATCTCAAGAAGGAGGAGAGGAAGCTTCTGAACCGGTAGTGGAGAGGAAGTTGAAGGATGAAATCATGAAACTGGCAAACATAAGGGCGTCATCCAAGATCAGGTCAGTTAGTAATTTTGCATTCAAGCATAGTCCTTGTTTGTGTTACTGTTATCAAGTGTTCAAAGCTATTTTTTGACATCTACAGATCAATGGACTGCCTTTTGGTTCCTAACGGAGAGATGAAAGTTGTTCTTCTTCTGCAAAATAACACAGTGGAGACATACACGCTGAAGACTACAGAGAAGAATCCCACTGGGAATAAAACCTCTCGCCTCACACTGGGTGGTCACCGTTCAGATGTCAGGACAGTGGCCTTCAGCTCAGATAACATAGCAATCCTTTCTGCCTCAGGAGACACTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30916
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003648 Nonsense 316 938 9 27
ENSDART00000147892 None None 61 None 4
ENSDART00000003648 Nonsense 316 938 9 27
ENSDART00000147892 None None 61 None 4

The following transcripts of ENSDARG00000011079 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 21893057)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 21048843
GRCz11 9 20859712
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGTTTTTACTGTACTATCAGAGGAGGAAATCCAAAGAAAAATGGACAGA[A/T]AACTGAAGAAAGCCAAGAAAAAAGCCAAGTATGTTAGACCCTTGTTTTGA
Long Flanking Sequence:
CTCAGCTGTAAGAAAGCCGGGTCTATTCTGAGAGAAGCCAGAGACAGAGTTGTATCATTGGTTACAGATGCCAAAGCTAAAGTTCTAGCCTGTCATGTAAGTATGAGTTATATATTCAGCTTTGTTAGCTTTTTCTTACCAAACACAATTCCACAAAGAGGAATTTAAAAGGATAGTTTACACAAAAATGTAAATTCCTACTCACCCTTCACTTGTCACAATTCTGTTGAGTTTCTTTCTTCTGTTGAACCCAAAGGAAGCTATACTGAAGAATTTTGGCCATTGAATGGCTTTTGGTTTCCAACATTCTTCAGAATATCTTGTTTAATGCTCATCATAAAAAAGAAATTCAGCCAATAATGTGGAGATGTTAATTTTTGGGTAAACCTCCTTTAATGTATATCAAGAAATGTATTTTAAAACCTTTACAGGGCCTGGATGCTACCCTTGAAGTTTTTACTGTACTATCAGAGGAGGAAATCCAAAGAAAAATGGACAGA[A/T]AACTGAAGAAAGCCAAGAAAAAAGCCAAGTATGTTAGACCCTTGTTTTGATACCAATGATGAAAGTATGGTATCCTGATTGACTGTTATATTGTGCAGATCTCAAGAAGGAGGAGAGGAAGCTTCTGAACCGGTAGTGGAGAGGAAGTTGAAGGATGAAATCATGAAACTGGCAAACATAAGGGCGTCATCCAAGATCAGGTCAGTTAGTAATTTTGCATTCAAGCATAGTCCTTGTTTGTGTTACTGTTATCAAGTGTTCAAAGCTATTTTTTGACATCTACAGATCAATGGACTGCCTTTTGGTTCCTAACGGAGAGATGAAAGTTGTTCTTCTTCTGCAAAATAACACAGTGGAGACATACACGCTGAAGACTACAGAGAAGAATCCCACTGGGAATAAAACCTCTCGCCTCACACTGGGTGGTCACCGTTCAGATGTCAGGACAGTGGCCTTCAGCTCAGATAACATAGCAATCCTTTCTGCCTCAGGAGACACTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34610
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site, Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003648 Essential Splice Site 888 938 27 27
ENSDART00000147892 Splice Site None 61 None 4

The following transcripts of ENSDARG00000011079 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 21905624)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 21061410
GRCz11 9 20872279
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTATAGGAGCAGATTGGGTAAGGCTCTGTTTTCTCATTTTCCTGTTTTC[A/G]GGATGTCCTGGGTTTCAACAGCGCTGGTCTTCAGTTCCTGCAGCGGGAGA
Long Flanking Sequence:
TAATATGCTTAAATGTAATTTTAAACAATAATTTTAAACCAGAGTTCATCCAGTGTTCAGATTTTTCTACTATAAATGTATGCAGATTAACAGATATTTACTTTAATAATGCCTTGCATCTTTAAACATGACATTTTAGAAAATGTGTAATATAAAAAAATCATTCTTAATGTAATAAACCAACTGAGAAAGCATGGTGATAATTATTATTTTTGCTGTATTATTTTTTTTTACCCTATTTACCTGCAGTGTATTAGCATAAATCTAAATTACTGCCATGTCACTGTATTTGACCCTAATTTACCGTTTACCCAGAGTCCACTTTGGTCAGATCACCAGTAATCAGATGCTGCTGTCTGTGATTGATGAGTTACGGGCCAACACGATCTCTAAAGTGCGAGAGATCAGGGTGAGTTTGTACTGTATACTGTAGCCACTGCAATCTCATCTCTTATAGGAGCAGATTGGGTAAGGCTCTGTTTTCTCATTTTCCTGTTTTC[A/G]GGATGTCCTGGGTTTCAACAGCGCTGGTCTTCAGTTCCTGCAGCGGGAGATTGAGAGCAGAGAAGATGTGACGTTCTTTGCTGATGCCACAGACCGCTTTGAAGAAAAGAGGAGAAAGAGGAGGAAACGGGAAAGAGTTATTCTCACAATCACATAACAACCAGGACAAAACTGACATGACGCTACTGCTGTGTGCTTTTACAGTCAGCATGTATGTATGTATTCATTGTTCTTTTGTACTCGCCTCAAGTTCATAAAGGTGAATTTATCCACAAATCAACTTTAATGAGACTGTTGTGTCGCTTTTTTTACTTCAGCGTTTTCAATATCAACAGTAATTGATAAACCTTTAAATATAGACCTGCTGTGATCTCAGAGGTTGTGAAGTTTGCAGTTGTTTTTTTTTTGTTGAATTCACTTACATTTGGAAAAATTATCAAGTTAACTTAATCGGTTTCTGTTGGGACAACATGAAGGAATTGTTTGAAACCCAGCATTTT
Associated Phenotype:
Not determined