ZMP
pbx3b
Ensembl ID:
ZFIN ID:
Description:
pre-B-cell leukemia transcription factor 3b isoform 1 [Source:RefSeq peptide;Acc:NP_001091713]
Human Orthologue:
PBX3
Human Description:
pre-B-cell leukemia homeobox 3 [Source:HGNC Symbol;Acc:8634]
Mouse Orthologue:
Pbx3
Mouse Description:
pre B-cell leukemia transcription factor 3 Gene [Source:MGI Symbol;Acc:MGI:97496]
Alleles
There are 4 alleles of this gene:
Allele Name | Consequence | Status | Availability |
---|---|---|---|
sa2431 | Nonsense | F2 line generated | Not yet available |
sa8808 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
sa41256 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
sa41255 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa2431
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000006685 | Nonsense | 98 | 261 | 2 | 5 |
ENSDART00000040126 | Nonsense | 98 | 297 | 2 | 7 |
ENSDART00000048994 | Nonsense | 106 | 238 | 4 | 10 |
ENSDART00000098822 | Nonsense | 113 | 276 | 4 | 8 |
ENSDART00000105204 | Nonsense | 113 | 312 | 4 | 10 |
ENSDART00000140420 | Nonsense | 98 | 287 | 2 | 6 |
The following transcripts of ENSDARG00000013615 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 8 (position 34773418)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 8 | 33850919 |
GRCz10 | 8 | 33943631 |
GRCz11 | 8 | 33918627 |
KASP Assay ID:
554-2889.1 (used for ordering genotyping assays)
KASP Sequence:
CACAGGCATGTAATGAGTTCACTACCCACGTAATGAACCTGTTGAGGGAA[C/T]AGTCTCGCACACGGCCCATCTCGCCCAAAGAGATTGAACGCATGGTCAGC
Long Flanking Sequence:
ATCGGCATTTGCATTCATAGATGACTTCACCTATTAAGCCGTTCAAGTGCTCAGCAGCACTACAAACAGTATATGGATGGTGTTTTTTCCCAGCTTTCAAGAGCAGCAGCTTTGAACTTGCTTCAAATATTGCTGATTGCTGCTCCGGAGAGCTTCAAACGAATGCAGTTGAACTGATGTGCTTCTTCTGCGGAATAACGTCAAAGAGCATTTCTGTCATTTCTGAGTCGAGACTATATAGCGATTTTAAAAGGAGGGTCGATCTCTAGGAAGTTTTTTTGGGGGGTTTAAGTGAAGATATGATGAATTGTAGATTCAGAAATTATTTATTGCACGTAGCTGCTGAGTCTCGGTAGTGGGTCCTAAAGACTTTGGAATGATTTGATTTTTTACACCTACATCCTCAGTCGGAATTAACGCTGCAGTCTTAAACTCAAACTTGTCTTTCTCCACAGGCATGTAATGAGTTCACTACCCACGTAATGAACCTGTTGAGGGAA[C/T]AGTCTCGCACACGGCCCATCTCGCCCAAAGAGATTGAACGCATGGTCAGCATCATTCATCGCAAATTCAGCTCCATCCAAATGCAGCTTAAACAGAGCACCTGTGAGGCTGTCATGATCTTGAGGTCCCGCTTCCTTGACGCCAGGTTGGTGTCCTCAATTTTATTTGATTTTTTTTAGAATGTGCATGTACAAATTATTCTCACTTGTGTTTGAAAGAATATATCTTCTACTTATCATCTGCAGATATATGTTATTCAAAATGACAACTCATAATTGCATTTATAGAAACACAGAAAGTCTTGGTACTTTGTTTCTTGAATTGTTTCTTGAAGTATGAACTTTTAACCTACATACCCAGGGTTAAGGCAATCCCACTGATGGAACGGCACCTGTTATAAGCCATGAGCAATAATGTATTCAGCATTATTCAACCACTAGCGGTTAAGATGGGGTGTTGCCAAGACAAGGGTTTTAGAGCTTAGAGGCCATCCACCGAAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa8808
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000006685 | Essential Splice Site | 191 | 261 | 3 | 5 |
ENSDART00000040126 | Essential Splice Site | 191 | 297 | 3 | 7 |
ENSDART00000048994 | Essential Splice Site | 200 | 238 | 5 | 10 |
ENSDART00000098822 | Essential Splice Site | 206 | 276 | 5 | 8 |
ENSDART00000105204 | Essential Splice Site | 206 | 312 | 5 | 10 |
ENSDART00000140420 | Essential Splice Site | 191 | 287 | 3 | 6 |
The following transcripts of ENSDARG00000013615 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 8 (position 34772070)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 8 | 33942283 |
GRCz11 | 8 | 33917279 |
KASP Assay ID:
2260-0861.1 (used for ordering genotyping assays)
KASP Sequence:
AAGAGGCCAAAGAGGAGCTGGCTAAGAAGTGCAGCATAACAGTATCCCAG[G/A]TGAGACCACACCCCTTTTACAGCAGNNCACATGCCCAGTTTGTTGGAYAGTC
Long Flanking Sequence:
CCTGCCCCAGTACTTGAGGAACAGTGTTCAGCTGGCCATGGCTTGATTTCCCTAATGTCCCAAGATACAGCTCTGACTGGGAATGCTTGAGCACCTCTAAACGCCCCCATCAGAATGAAAGCACAAGAGAGAGAGAGGGAACGCTTGTCGCTCTAAACACTGAACATTTCACGCTTCGCTTAAAGCTCAACTGATAACGTAACAATGTCCATTTGCGCGTCTACATATGTATTCCGATAATAGCCTTCCCGACTTCATTTCCTGCCAGCAGCTTCATTATGAGTTTGGCCATCTCACAAGGTTTTATTTGAGTCTCTAATTGCCTTCCTCCTCTTGTTTCCCTCTCCAACTTGTCCAACGGCAGACGGAAACGGCGGAACTTCAGCAAGCAGGCGACCGAGATCCTGAATGAGTATTTTTACTCGCATCTTAGTAACCCTTATCCCAGCGAAGAGGCCAAAGAGGAGCTGGCTAAGAAGTGCAGCATAACAGTATCCCAG[G/A]TGAGACCACACCCCTTTTACAGCAGCACATGCCCAGTTTGTTGGATAGTCTAAAAGAAATATTTATCTGTCAAAGTCTGAAGATTTAGTGTACCTATATACAGGCAATAGTTGGGTAAATTCAATTAAGTCCAATCCCTGCTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACAAATCAATGGTTAAAATGCTGGTTTAAGATGGTCCATTAGCCTGGCTAGGTTGGTATTCAGCTGGTCTAACTCAAGGATCTTAAGTTAAGTCTTACTGCAACTTCAGAAGATGTTCCTTAGCTAGTTCAGGTGTGTTTGAATTAGGGGCAATCATATCACTACTCTGTGCATTCTTTTAACTTGGTAAATGTAGGAGACAGGAAATACAATGTCTGAAAGTCATTGCATTCCATTGTTCAAATATGGTGCCCTGCAAATTCGTATCACATGAAGATGTGTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa41256
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000006685 | Essential Splice Site | 247 | 261 | None | 5 |
ENSDART00000040126 | Essential Splice Site | 257 | 297 | None | 7 |
ENSDART00000048994 | Essential Splice Site | None | 238 | None | 10 |
ENSDART00000098822 | Essential Splice Site | 262 | 276 | None | 8 |
ENSDART00000105204 | Essential Splice Site | 272 | 312 | None | 10 |
ENSDART00000140420 | Essential Splice Site | 247 | 287 | None | 6 |
The following transcripts of ENSDARG00000013615 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 8 (position 34764688)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 8 | 33934901 |
GRCz11 | 8 | 33909897 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCGCCGTCCAGAATAGTCAGACCAACTCACCCACCACACCCAACTCCGG[T/G]AAGCTTGCACCATTCCCGGACGAGCCCCCTAAAAACCAACCAGCCATCCA
Long Flanking Sequence:
CATTAGCTACCTGATCCCCTAAGCACAACACTGATCCTAATTTTGCCACTAGACAAGCAGCCCCTTGTGTGTTGGTTTTGTCTAGAGACAAACAGAGAGCATGTCACGCCTCCATCCGCAATAACGCACAAGCCCTGTCTGATAATCGCTTAATTAGTCTGCATGCCCAGCGGATATTACTGTGGGAGGCTGGGGACTGTGGACTTGATGGACCCAAACATGACATCTTGAAACAATCACTCTGCTCAGTGCACAGTGCCTCGTCTGCATTGACGTCTGACGCCCCCTCCTCTTTTTTTTCCCCCTTTCTTTTTCTTTCCATCTCTCCCCCAGGTATCCAACTGGTTCGGCAACAAGAGGATCCGCTACAAAAAAAACATCGGCAAGTTCCAAGAGGAGGCCAACCTGTATGCCGCTAAGACAGCCGTGACTGCAGCACATGCAGCAGCTGCCGCCGTCCAGAATAGTCAGACCAACTCACCCACCACACCCAACTCCGG[T/G]AAGCTTGCACCATTCCCGGACGAGCCCCCTAAAAACCAACCAGCCATCCAAAATCCCAGTTTGGTCCCTTCTGAACCTCTGCTCCCTTTGGCACGCTGGTTGGTTGCTGTGACAGTGAGAGGTCCCAGCCTGGGGGATGAGCCTCACTCTCCTGCCTATGAGACTATACATGCTGAACGAGACGAGCAAAGTCAAGCAGAAACTGTGTGCACATGCTGAATATGTTTGCAGAATTGAGGGGTGGGAGGGTGGTGGTGCTGGTGGGGGTAGAAGAGATAATCTTCACCCACTGTCCTCCCTTCCTATCCATAAATATGTGACAGTGTTACCCCCGCTGTGAATTGATGGAAATCTCTTGCTCGGAGCATGTTACGCTCTTAAAGAAATGTATAGTTTGGAATGATGATGAATATTTTATTAGTAGAATGATGCAGTGTGTAGCTTAAATGTATGCTCTTTAAACATAATAAGCAGAAGATTTGACTGTAATATGGACATGG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa41255
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000006685 | None | None | 261 | 5 | 5 |
ENSDART00000040126 | None | None | 297 | None | 7 |
ENSDART00000048994 | Essential Splice Site | None | 238 | None | 10 |
ENSDART00000098822 | Essential Splice Site | None | 276 | None | 8 |
ENSDART00000105204 | Essential Splice Site | None | 312 | None | 10 |
ENSDART00000140420 | None | None | 287 | 6 | 6 |
The following transcripts of ENSDARG00000013615 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 8 (position 34761170)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 8 | 33931383 |
GRCz11 | 8 | 33906379 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAATGATGTCCTGGGGGGGAATCCCATGTATAGTCCACATGGCTTGAATG[T/A]AAGTATAGTCTCAGTCAGCCTTGAAGAGGCATTAATAATAATAATACACT
Long Flanking Sequence:
GCACTAGTTGTCTCAATCTATATTCTCCTCCAACTGTTGTCATGTGTGAATATTTTTGTGCTTTGTTGAAATTTCCCTATCATAATTATGCCATTCTTTCTTTATGTATTTTTTGTTTTTTTGAACTCTGTGTTGAACACCAGAAACCTTTAGAGAGGGGAAACACATATGCTGTCTAAATGTTGCATTAAACCACATATGTATTCCTAACTTCATCCGGCTGGATATTCCATTTAGTATGATTCATTTAGTAAACCTCAGAGCCATCTTTTTTCGTTGTTGTTGTTCTTTTTTTCTTTAAACATCAGTGCCTTTGTCCGTTTAACCACACATTTCTGTGTTGATGTTTGCACGTGTTTCTGAAATGCAGAATGTTGACAAGCTTGAATTTCTGTTGTGTCCTCTGCAGGTGGATACCCTGCGCCATGTTATCAGTCAGACGGCAGGATACAATGATGTCCTGGGGGGGAATCCCATGTATAGTCCACATGGCTTGAATG[T/A]AAGTATAGTCTCAGTCAGCCTTGAAGAGGCATTAATAATAATAATACACTTACTACACTATTAACTTTTTTAGTGTTTTGAAAAGTGTACCTCTTACATTTAAATACAGTTAAAAATATTCCTGTAATAGAAAAGGAGAATTTTTAGCAGCCATTAATTAAGTCTTCAATGTCAACTGACCATTCAGAAATCTTTCTACTGTTATGATTGAGTGGTTGAAAAACATGTTTTGATTGAGTGATTGATTGATTGATTGATTGTGAAATGATGATAGTTGTTTTTATTTTAGAAAGCTCAAAAGTACAGCATTTACACTCACAAGTCACTTTATTAGGTACACCTTAATAGTACCGGGTTAGACTCACTTTTGCATTAATGCTCCATAGCATAGATTCAACAAGGTGCTGGAAATATTCCTTAGAGATTTTGGTCAATATTGACATAATAGCATCACACAGTTGAAGCAGGTTTGTTAGCTGCACATCTAAGATGCAAATCTC
Associated Phenotype:
Not determined