Busch Lab

ZMP

ptgesl

Ensembl ID:
ENSDARG00000068415
ZFIN ID:
ZDB-GENE-040426-1063
Description:
Prostaglandin E synthase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q7ZUC7]
Human Orthologue:
PTGES2
Human Description:
prostaglandin E synthase 2 [Source:HGNC Symbol;Acc:17822]
Mouse Orthologue:
Ptges2
Mouse Description:
prostaglandin E synthase 2 Gene [Source:MGI Symbol;Acc:MGI:1917592]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa10731 Nonsense Available for shipment Available now
sa41245 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa10731
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098936 Nonsense 111 377 2 7
ENSDART00000129882 Nonsense 112 378 2 7

The following transcripts of ENSDARG00000068415 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 31856838)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30999564
GRCz11 8 31008796
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TATTGTTTCAGGCATCAGATCTGGACACAGACCTGAAATTGACTCTCTAT[C/T]AGTATAAGACCTGTCCGTTTTGCAGCAAAGTGCGAGCTTTCCTGGATTAT
Long Flanking Sequence:
TGTCATTGCGCTTGCCGTAGATTTGTGGGAGTTTATGTAAAATCATGATGGCGGCGGCCTGTACGAGAACGCTGGGTAAGGTCGGCCGGTTAGTTTTAGACACGCCGACGTGCCGTTTTACAAACACTGCGGCATTCGTGCCGAGAACCTCCATGAGATGCCAAGGGAGAGCTTACGGTACCGGTAGCTCGGGGTTTAAATCCAGACTTTTGCTCGCGGCGCCGGTGCGAGGCAGTGGCAGAGTCCTGGGATGCGCCTTCTTGCTCGGAGGTGGTTTCGGCTTGTACCAGACCATCAAACTCACACTTCAACATCACCTTGCAGAGAAAGAAGCTGACGTAAATATACACGAATGTGCAATGTCTGACACCCTTGAAATTTTCTCGTTGACGTGCAGCTGTTGAAAGTCCAATATGTGTAATTTTTAGTTTGCTGGCTTACCTTGATTTTTATTGTTTCAGGCATCAGATCTGGACACAGACCTGAAATTGACTCTCTAT[C/T]AGTATAAGACCTGTCCGTTTTGCAGCAAAGTGCGAGCTTTCCTGGATTATCATCGACTGCCATATGAAATCGTGGAGGTCAATCCCGTTATGCGGCAGGAGATCAAGTGGTCGACCTACAGAAAAGTCCCCATCCTGATGGTGAACGGGACGGTGGTATGTAGTCTTTCCTGATTATGGATAGTGAAGTATATGATGCTTCTGCTCACAAAGTCTCTTTCTTGATCGATTCCTCAACAGCAACTGAATGACTCTTCAGTAATTATTAGTGCTTTGAAGACATACATTAGCAGCAAGTGAGTATCTTCTGCTTGAATAGTTTTATTTTATTTGTATGGATGTTATTGTTAGACTATTTATAAGATATGTCTGCATAAAAACAAATTCTAATCTACAGAATATATTGATATACTTATTAAAATGGGAATTATAATTAAAACATCATTACAAATTTAGTTTTTTTGCCTGATAAATGGATAAATCAGTGACAACGTATAATGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41245
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098936 Nonsense 244 377 5 7
ENSDART00000129882 Nonsense 245 378 5 7

The following transcripts of ENSDARG00000068415 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 31858973)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 31001699
GRCz11 8 31010931
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTTATTTCTCAGAGAAGAGATTAAATGGCGGACATGGGCAGATGATTG[G/A]CTGGTGCATCTAATTTCCCCAAATGTTTACCGGACGCCAACTGAAGCCCT
Long Flanking Sequence:
GTTTGACGCAGAAGTATAAATCAGCCTTAAGGAGTCCATTTTTATTTTGGGTTAACTATCCCTTTAAGTACTGCATTCATTTTTGTGATTGCTTCTTCGCTATAAAAAAGTTGTGGTTCTGTTCATTCTGGCAAATGAATGTAAATTTAAATGCAAATTTGGATGGTCTGTTTTCTCCTCCTAGGGACAAAAAGATATCTGAGATTCTTGCTTGTTATCCTGAAATGAAGTCAAAGAACGACAGAGGGAAAGACGTGATAGAGTTTGGCAATAAGTACTGGGTCATGGTGCATGACGCGGATGCTGATCAACTATATCCTGGAAAAGACAGCAGAAAGTAAAGCAAATCAGTTATGTCTGAGAGTGATTGCATTCTCAACATTTCATTTTTTATTTACTGTGTCAAACAATAATTTAGCTTTATGGGGCTTCCTCTATGTTTCAATAACATTTTTATTTCTCAGAGAAGAGATTAAATGGCGGACATGGGCAGATGATTG[G/A]CTGGTGCATCTAATTTCCCCAAATGTTTACCGGACGCCAACTGAAGCCCTCGCATCTTTTGACTACATAGTACGGGAAGGGAAATTCGGTTCCTTCGAGGGCTTTTTTGCTAAGTATTTTGGAGCTGCTGCCATGTGGATCATCTCAAAGAGATTAAAATATAAGTATGCACCTGTTGGCAGTGTGTAAATAATATGTAAAAAAAATGATTTGATATTAAAGTTAAATTTGCTCGTTCTACAGACACAATCTGCAAGCTGATGTAAGGCAGGATCTTTACAAGGCTGTCAATGACTGGGTGGCAGCCATTGGAAAAAACAAGCAATTCATGGGAGGTGATGAACCCAACCTTGCAGATCTGGTATGTGTTTTTCTGATAGACAGAAATTATATTAATAGAAATACACTTTATTTCTGTAAACTGGGGTCTATGAAAGCTTTTTCCACCACTAAATGAAAAAAAGGTTATTGCTACTTTTTAGCTCAGAATTCAAAATCCT
Associated Phenotype:
Not determined