ZMP
si:dkey-48j7.2
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to H.sapiens PREX1, phosphatidylinositol 3,4,5-trisphosphate-dependent RAC exc
Human Orthologue:
PREX1
Human Description:
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 [Source:HGNC Symbol;Acc:325
Mouse Orthologue:
Prex1
Mouse Description:
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Gene [Source:MGI Symbol;Acc
Alleles
There are 12 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa21300 | Essential Splice Site | Available for shipment | Available now |
| sa21299 | Nonsense | Available for shipment | Available now |
| sa12745 | Essential Splice Site | Available for shipment | Available now |
| sa17372 | Essential Splice Site | Available for shipment | Available now |
| sa17713 | Essential Splice Site | Available for shipment | Available now |
| sa21298 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa21300
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000078022 | Essential Splice Site | 115 | 1622 | 3 | 40 |
| ENSDART00000136869 | Essential Splice Site | None | 56 | 4 | 7 |
| ENSDART00000138289 | None | None | 807 | None | 18 |
| ENSDART00000141279 | Essential Splice Site | 115 | 777 | 3 | 21 |
Genomic Location (Zv9):
Chromosome 8 (position 26375387)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 25503305 |
| GRCz11 | 8 | 25522444 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCCTGAACCCCAGGCGCATCATTCTCTCGGACATGTTTTTCTCCAGTTT[G/T]TGAGTCTAAGAGATTGCATTTCAAATCATCTTTGAACTAGTGCTTTGCTG
Long Flanking Sequence:
TCAGGAGCAGGTCAAGGTAAAACCAATAACACGCACAAAAACCTTTACATGCAGATGTAGAAAATATGCAGTACATCCAGATGAATTGAGCAAACCACAGGCAAACAAATTATTCTAGTTTTCTAGCCATCTTGTAATTACAAAATATTTGGACTCATACTTGTTGCACAGAATTTATTATATTTATTCAATCGTAGCAAACCTTTGAGTGGAATATTTACTTAAAGCTGCATTTCTTTAAAAGAAAGCCCTGTCAGTTTGATACCAGTGCGACAATTTTAGTGTAACATAGATGTCTGAATGCTTCGGGAGGAAAACATCAAGAGCCTTCATTGTCGCTGATTTTCTGAACTATTGTTTTTATGCTTTCTTCACAGGTCTTGTTTTCCAACATCGAATCCATTTTGGATGTCCATCGCGAGTTCCTTTCCACTCTAGATGCCAGTTTGCAGCCTGAACCCCAGGCGCATCATTCTCTCGGACATGTTTTTCTCCAGTTT[G/T]TGAGTCTAAGAGATTGCATTTCAAATCATCTTTGAACTAGTGCTTTGCTGCGTAGCAAAAAAAACTTGAGTGTCAGTCAAACCTCAAAATCTTACTCTCAGTTCATCCCAGTGTTTTCCCAGTAACCAGATTGCTCCATTCTCTCAAAACAGCCTCAATACTGCCTCCCTTCCCTCTGTTCTTAAAGAAAAAGTGTGTAAACATGTAGCCATATGACCAGTGTAATAAAAAAAATGACCTTAATAGGTGGCACTGAATTCCAGTTGTAGCAACATGTTCAGTTCAGACAGAAGATGGAAAGCTTTAATGATGTCTGTTTTAGCAGTTATCTGTGTTTTATTAGATCTTAGATCATTAGATCAGCACTTCAAGAAAACATCCATATTCCGATTATTATTTAAGTTGTTGGTTTGTTAACTTTTAAAGCAGTGAAAGGTAGTTTTATTTATGAAAATAAAAATAGTTCTTGAAATGATCATAGGTTAAGCTCAAAGTATATA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa21299
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000078022 | Nonsense | 154 | 1622 | 5 | 40 |
| ENSDART00000136869 | Nonsense | 18 | 56 | 6 | 7 |
| ENSDART00000138289 | None | None | 807 | None | 18 |
| ENSDART00000141279 | Nonsense | 154 | 777 | 5 | 21 |
Genomic Location (Zv9):
Chromosome 8 (position 26368897)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 25496815 |
| GRCz11 | 8 | 25515954 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATTAATCAGGTCATGTGTTTTTTTTTTTTTTTTTTTCAGCACCTCATGT[T/A]GTTAGGTGGTAAGAAGAGCACAGATGTTCCTCTTGAAGGGTATCTCCTCT
Long Flanking Sequence:
AAACAAAAAGTATTTTGAAGTATAACTCTTTTGTTTCCTCTACAGAAAGTGCGTTTTTCAGTGTATGGCGAGTACTGTAGTAACCATGAGAAAGCACTCAGACTACTGATGGAGCTCAACAAGATCCCTCACATACGGGCTTTTCTGCTGGTAAGCACCACTTATATGTCTGATGCTTTCAAAAAAAAATCCCATCATTTTTATTATATCATATTCTGACGAAAATCCCTCATACGCCAGTACTGTCACTTCAGTTCTGCATTTGTAACCCAGCAACAGATTTCATTGCTGATTGTCGTGAATAAACATTACACATACACTCATTAATTTTAATCTCCAAAATTATTTGAAGTGAAACTGATACCTAAAGTTATACTGTAGAAATCGAGAGTGTCGTTCAGAGCTTTCCATGGAAACTCAACATGTATCTGTTTAGATAGAAGGATGTTGAATTAATCAGGTCATGTGTTTTTTTTTTTTTTTTTTTCAGCACCTCATGT[T/A]GTTAGGTGGTAAGAAGAGCACAGATGTTCCTCTTGAAGGGTATCTCCTCTCGCCTATACAGAGGATCTGTAAATACCCTTTGCTATTAAGGGTAAGGCTACCTTTTTCGTTATAGGCAAAGATGTTGTTTGTTTTTGGGACATGGTTGGAAACGGGTTTTTGTGCATCAGTATAATAAAACAGTGAATTATAGAATTTTTTTCTTTTGACGTTTTAGAATGTGATTAGTTTACTGTTATTTTTATGTGAGTAATACAGTTTCATCGCCAGCCTGCTGAAAGGGGTGGTTCTTTTTTCTCCTTGCAGTTATATGCCTCATTTTCTATTTAATTATGAAGTTTAAATGTTGCATTTTAGTGACATTTTAAGCACTTTTTTGAGCTTGAGATTTAAAATGAAGAAATATGAAGAAAAAAAGATACATTTTTAAAAAAGATATTTATTGTATCATATATCATTAGAAAAAAATATCTGTTAAATTTTAAAGTTTAAAAACTGCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa12745
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000078022 | Essential Splice Site | 684 | 1622 | 18 | 40 |
| ENSDART00000136869 | None | None | 56 | None | 7 |
| ENSDART00000138289 | None | None | 807 | None | 18 |
| ENSDART00000141279 | Essential Splice Site | 684 | 777 | 18 | 21 |
Genomic Location (Zv9):
Chromosome 8 (position 26316029)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 25443947 |
| GRCz11 | 8 | 25463086 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCTGTATACRCCGCTCACTCAGACTGCTGGTKGCCACCAAGAACAAAGAG[T/C]GAGTCCAAGTTCATGGAAGAAATCAGATACACAGACCTGTTAAAWGTAAC
Long Flanking Sequence:
CTCTTCTCTTGTTTTTCTATAGCTCCTTCATTCTTGCCTTCCTTTCTTCCTTACAATCACACATTTTTAATCACACCATCAAATGAACTGCCCGGTGATCTGAAAGTCCAGATTACATCTTATAAAGCTTTTAAGCTATATAAAGCTCTCTTGCCATAAAGGTGCGTTTTCTCTCAATTCATCCAATAATCCTCATTAACATATCACTTATCTCTTTTCCCCAAGCTCACGCACAGCAACGAAAAGTGTTATGAATGACATCCTCATTTGCTTTCCTCTCGTTGTTGATTTTTGTCAGCTGGATTCTTGATGTTTATTCCGTTCATTTCCATGTTTTGCCTTTTGCGCAGATGGCAGGCCTGCAGCCGGGGAGAAAGATCTACTCCATTAATGAGGACCTGGTGTTCCTGAGGCCCTTTTCTGAAGTGGAGACCATGATCAACCAGTCTTTCTGTATACGCCGCTCACTCAGACTGCTGGTGGCCACCAAGAACAAAGAG[T/C]GAGTCCAAGTTCATGGAAGAAATCAGATACACAGACCTGTTAAATGTAACCACGTACAGTGTAAATGGACACTACTGGTATTATAGTTGCACTACAAAACATTGCTTTCAAAAGAGAATGCATTAATGTTTAAACAGCTGTGGGCACTTATTGTTTTTGATGTAGACAGTTTAATGTGTCCCTAATAAAGATATCACTGAAAAGAAATATTCTGCTTAACAGCACAGAGAGGAAAAAATGCATATTGTGTTCTTGTGTGTGTGTGTTTGTGTGTCTAATAGGATTGTAAAGATCCCAGATGTTCATGGCACCCTTCCGTTTGTTCTCTCTGGTTCTTGTCCACCTCACATTCATGCAGTGAAGAAAGGTGAGTTCTCATTGTTTATGAGCTAAAAACACCCGCACATCATCAAGTTCATAAATAATTATGGCCAGACCCATTCAGCTTTTTTTTCTCTTCGTAAAAAATCACACACGTCATTCTGAAATAAGGAAAGTAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa17372
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000078022 | Essential Splice Site | 1266 | 1622 | 31 | 40 |
| ENSDART00000136869 | None | None | 56 | None | 7 |
| ENSDART00000138289 | None | None | 807 | None | 18 |
| ENSDART00000141279 | None | None | 777 | None | 21 |
Genomic Location (Zv9):
Chromosome 8 (position 26295960)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 25423878 |
| GRCz11 | 8 | 25443017 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTATTATTGTTGGTTGGATTATATTCATGTMTGTTTGTAACTCTGTTGC[A/T]GATGGAAGGAGTCAGCTCTTGCTGGCGCTGCTTAAATGCACGGGTAAGCT
Long Flanking Sequence:
TACGTTTTGCACAAGAACATCCAGGAGGACCCTTGGAACCTTCCTATTTCGATCAAATCTCTAATTAACAGCCTTCACCGCTTTGTAGAGGGTATGTTTACGCCTGAACGATGCTTAATGGCAGTATTAGTAATACGCTGTCTAGATTTTTCTTGTGCATACTGTAGATCATCAGTGTATATTATTTAATACATTTAATACACATATTTATTATACATTAAATACACATATAGATACATAATATTATTTAATACACATATTTCACCACTTACAAAACATGACCACTGGATATGTCTTTAATAATATACTTTTAACAAGTTATTTAATATCAAACTTATTTTAAATGTCGAGTTTTTAGAGTAATGTAATGTGTTGACAAACACAGCAGGCACACATCTGTCCAGTGTCCATGGGATTGCAAAACTGTTTCCAAAGACTTGCAATATGTGTTGTATTATTGTTGGTTGGATTATATTCATGTCTGTTTGTAACTCTGTTGC[A/T]GATGGAAGGAGTCAGCTCTTGCTGGCGCTGCTTAAATGCACGGGTAAGCTAAACCTCCATTCATAGTTTTCCTCAGTTGAACTTCAAAAACCTTTTGAAAATCAACCCCAAAATGTTTACATGATTTTGCTTGTGTGTCATCACCTGTTGAGAATGCAACTGCGCGCAGCTGTGGTGTGTGTTATTTTTCATTCTGCACTACTGTTCTAGGTCATACTGTATTTATGTGCTGTGATAAGGGAGTGTTTTTAAGGATTCTGTGGCAGGGAGTGTGTGCGGCGGGGTGTGTCTGTTTGCAAGCTTCTAAGCGAGCAGTAGACACAGATAAAGTGGAGAACAGAGAGAGTGGGTTCGTCCCACGGGGTCTGCGGTGGAGACATATGGAAGCTGTTGAGCGTTTGCTTTGGAACCCGATCTAGAGCCCTTATCCTTCTTACAGCAGCCCCAAACCCTATTCTCACCCCTGGTTACACTGAAACCCACCATCTGCTTAAAGCATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa17713
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000078022 | Essential Splice Site | 1435 | 1622 | 35 | 40 |
| ENSDART00000136869 | None | None | 56 | None | 7 |
| ENSDART00000138289 | Essential Splice Site | 620 | 807 | 13 | 18 |
| ENSDART00000141279 | None | None | 777 | None | 21 |
Genomic Location (Zv9):
Chromosome 8 (position 26285040)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 25412958 |
| GRCz11 | 8 | 25432097 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACAGCACTGTGCAAAGAGTGAATGTAATATGCATTTTCTWAACTTTTATC[A/C]GGGCTGGAGAAGCCAGAAGGTGTGTTGTCTCAGGATTTTGTTACCATGGA
Long Flanking Sequence:
AATGTCTTTTTCTTACAACATGAAGAGAGGGTTGCTTTGGCAAACTTACATTAGTATATGTGAATAAATTAAAATAATAATAAATTATAATAAATTAAATTTATAATAAATATTTTAAAGAGCAATCCTTAACATAATAACCCCAGATCACATATTTATAAGATAAGGAAAATGGTTTTAAAATATTATGAGAAATAAAAGCTTCAACATTATTTCAAAAATGTTTTCTATATTGGCAAAAATGTTTACGAAAAAGAATGAGAAATAGTTTCATTAAAGCTTTCACAAAAACAGTGCTCTAATTCAAAATCAATTAGACATTTTTGTAGAAATGCTTTTGTAGGATAAACTATATATTGTTAATGTACAGTCGAGGTCAGAATGTGCTCGTTCAGATCAATGTTTCCTTGGTGAGTCTTGGTCTCCATCTAGTGGTGTTTGTAGAGCATTACAGCACTGTGCAAAGAGTGAATGTAATATGCATTTTCTTAACTTTTATC[A/C]GGGCTGGAGAAGCCAGAAGGTGTGTTGTCTCAGGATTTTGTTACCATGGAAGAGTTTCAGCAACGCACAAATGCTCTCTCACTGGAGAAGGTCAAAGGTTATTACCGCAAACTCAGGTAAGGACCTCTCTTTAGTCATGTGGGAATCATCTCATGTAAACTGTGAACAATCTTCAGTGTCATGTGAGCTTCAGAAATCCTTCTAATGTGCAGATCTGATGCTCAAGAACTCAATATTTGGTGCCATAACACTGGTTTACAATCATAGCAAGTAAAAACATCTGTTATTGTGAACATTATTGTGTTATTTTGGGGGGGAAATTGCTCTAAATTACTGTTTTTTTTTATTTATTTAAAAGATATGTTATACTTTCAAGTGTTCAAGTTGTCTGTTAATTTTTTGCTATATATAGATATATTAAAAATACTGATTCTTAAAAAATAGTCATTTGTGTTTATACATCTCTTCTTTATTTCTAGGGCTTTTTATCTAGAGAAGTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa21298
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000078022 | Nonsense | 1466 | 1622 | 35 | 40 |
| ENSDART00000136869 | None | None | 56 | None | 7 |
| ENSDART00000138289 | Nonsense | 651 | 807 | 13 | 18 |
| ENSDART00000141279 | None | None | 777 | None | 21 |
Genomic Location (Zv9):
Chromosome 8 (position 26284946)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 25412864 |
| GRCz11 | 8 | 25432003 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCATGGAAGAGTTTCAGCAACGCACAAATGCTCTCTCACTGGAGAAGGTC[A/T]AAGGTTATTACCGCAAACTCAGGTAAGGACCTCTCTTTAGTCATGTGGGA
Long Flanking Sequence:
TTAAATTTATAATAAATATTTTAAAGAGCAATCCTTAACATAATAACCCCAGATCACATATTTATAAGATAAGGAAAATGGTTTTAAAATATTATGAGAAATAAAAGCTTCAACATTATTTCAAAAATGTTTTCTATATTGGCAAAAATGTTTACGAAAAAGAATGAGAAATAGTTTCATTAAAGCTTTCACAAAAACAGTGCTCTAATTCAAAATCAATTAGACATTTTTGTAGAAATGCTTTTGTAGGATAAACTATATATTGTTAATGTACAGTCGAGGTCAGAATGTGCTCGTTCAGATCAATGTTTCCTTGGTGAGTCTTGGTCTCCATCTAGTGGTGTTTGTAGAGCATTACAGCACTGTGCAAAGAGTGAATGTAATATGCATTTTCTTAACTTTTATCAGGGCTGGAGAAGCCAGAAGGTGTGTTGTCTCAGGATTTTGTTACCATGGAAGAGTTTCAGCAACGCACAAATGCTCTCTCACTGGAGAAGGTC[A/T]AAGGTTATTACCGCAAACTCAGGTAAGGACCTCTCTTTAGTCATGTGGGAATCATCTCATGTAAACTGTGAACAATCTTCAGTGTCATGTGAGCTTCAGAAATCCTTCTAATGTGCAGATCTGATGCTCAAGAACTCAATATTTGGTGCCATAACACTGGTTTACAATCATAGCAAGTAAAAACATCTGTTATTGTGAACATTATTGTGTTATTTTGGGGGGGAAATTGCTCTAAATTACTGTTTTTTTTTATTTATTTAAAAGATATGTTATACTTTCAAGTGTTCAAGTTGTCTGTTAATTTTTTGCTATATATAGATATATTAAAAATACTGATTCTTAAAAAATAGTCATTTGTGTTTATACATCTCTTCTTTATTTCTAGGGCTTTTTATCTAGAGAAGTCTAATTCAGACTCGAATTCTACTGCCATGAAAATAGATCAGGTTGGTTGGCCGATTAAAATCCTGCTTGTATGTTTTGTTATTTTAAGTGTGTTT
Associated Phenotype:
Not determined