ZMP
ptpn18
Ensembl ID:
ZFIN ID:
Description:
tyrosine-protein phosphatase non-receptor type 18 [Source:RefSeq peptide;Acc:NP_001013470]
Human Orthologue:
PTPN18
Human Description:
protein tyrosine phosphatase, non-receptor type 18 (brain-derived) [Source:HGNC Symbol;Acc:9649]
Mouse Orthologue:
Ptpn18
Mouse Description:
protein tyrosine phosphatase, non-receptor type 18 Gene [Source:MGI Symbol;Acc:MGI:108410]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa41126 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa41126
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000014323 | Essential Splice Site | 460 | 513 | None | 17 |
| ENSDART00000109357 | Essential Splice Site | None | 221 | None | 15 |
| ENSDART00000132158 | Essential Splice Site | 461 | 514 | None | 17 |
The following transcripts of ENSDARG00000006308 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 8 (position 10188929)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 9605511 |
| GRCz11 | 8 | 9644096 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTGGTTTGTTAAGTTGTTAAACACTGTTAAATATATATTTCTTTTCCTC[A/T]GCTGAAAGCCAATCGTCTACAGATGATGATTATGAATACGTGTCTAGTGT
Long Flanking Sequence:
GGGGTAAATTTTGAAGCCCTTTCTCTTTATACTCTGTTTCAAAGGCCAAGGGGAAGAGTAGGGGTACAAAAATAGAATTGGGCCCTTATTTGACAAATTCAGATTACTGTACCAAACTACAATGCAAAAAGATAAAACGATTCAAGAACTCTAACCTGACTAAGATTCCCCAAATTCTCCTCCTCATAGCTATATTCTAATTTTCCACTTCAACGTTAATGCTTGATGATTTATTTTAACGCTCAATGCCATCATATTATATGCCAATGTTTCCATTATGAATGCATTCAAATACAGACCATGAAGAGTAACGCGTGTGTGTTTTTAGTAATGTAGAAGCATTTCGTTTCCCTTGAAGGCTCTTTATCAACCAAATAGGTGTGAAAAGCTAGCTAGCAGTAAACAGGAAGAAGTGTCAGATCAGCGTTGCTTTCACTCTCATGCACTGAGTTTGGTTTGTTAAGTTGTTAAACACTGTTAAATATATATTTCTTTTCCTC[A/T]GCTGAAAGCCAATCGTCTACAGATGATGATTATGAATACGTGTCTAGTGTTGTTAAGGACGGCAGCAGCCCATTTGCTCCGGGCAGCCTGGGTGAGTAATGCCATATGCACACTAAATCTCAACTCTGTACACAACAAGGAGACTGCTCAGACAAATATTTACTCTCAGATTGGGTTTTGATGAGTCTTTGGGCAAATTTGAGTGTTTTTAAATGCTCTTGTTGCTGAACGGCTGCCCAAATCAGTCGTTTTCATAAGCATGTGAGTTGCAAACATGCCAGTTAGTAAATAAAAATAAATAAATTTCTGCCTCACAAGCAGTCAACTGATCGATTGTTGGCAGATTATAGGCTTCTAGACCACACACAGACACACACAATAGAAAGTGTGGTTTCTTGTCCTCAATGTAGAAATAACCATTTCTGGTAAAGGCTGAACATCATTTTTAGGCCCTGTTTCGTATCAGTACTAACAAGACTCAATGGGTGGAAAGTAAGTAG
Associated Phenotype:
Not determined