Busch Lab

ZMP

apba2

Ensembl ID:
ENSDARG00000060639
ZFIN ID:
ZDB-GENE-030131-5371
Human Orthologue:
APBA2
Human Description:
amyloid beta (A4) precursor protein-binding, family A, member 2 [Source:HGNC Symbol;Acc:579]
Mouse Orthologue:
Apba2
Mouse Description:
amyloid beta (A4) precursor protein-binding, family A, member 2 Gene [Source:MGI Symbol;Acc:MGI:1261

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa34095 Nonsense Available for shipment Available now
sa20981 Nonsense Available for shipment Available now
sa40922 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa11600 Essential Splice Site Available for shipment Available now
sa13279 Essential Splice Site Available for shipment Available now
sa17752 Essential Splice Site Available for shipment Available now
sa44668 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa34095
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085661 Nonsense 55 796 1 13
Genomic Location (Zv9):
Chromosome 7 (position 32203671)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30596013
GRCz11 7 30867163
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGGAGGAGTATGAAGAGCACCATGACCCCGAGGTGACCCAACACTCTTA[C/A]CACAACCAAGAAGAGGCAGATTTGACAGACAGCCGACCGACTACGCCCAC
Long Flanking Sequence:
TCAGGCTCGATTTTCAATCACTTGAATTAATTTGGATATCCCTACTAAGTATGCTAATAAATACTCGTTTTTTAAACCCTGTTAACCTACAATGCCCTAAAGTAAAGTGATTTTTAAACACGTTTACCACATTTGTTTTAACTTACCATTGTAAACATCATGTTTTACCATGTAAATGTCTAGCTGTATGTGCGTCTTCCTAACTATCAGTGTTTCCTTCTCTTACTAAACTGACTGTTTTTATTGAGTATAAATTGTGAAAAATGCTGTCATACTTACTATACATCTGTCTTTGTTTGATAGGACTGAGGTTTCCAGTGATGATCGTCCTGTGAGTGCTTCTCAATGGCTCAGAGGAAGAGGCCAGGGATCAACAGCGGCATGGCCACAGAGCCTCATGCTCCAGCTCCACGCTCCTGTCCAGCCCCGTACCCTGACCCTGAGCACCCTGAGGAGGAGTATGAAGAGCACCATGACCCCGAGGTGACCCAACACTCTTA[C/A]CACAACCAAGAAGAGGCAGATTTGACAGACAGCCGACCGACTACGCCCACAACTCCCGACCACGCCCACAGAGACTACCACAGCCACCCGGACAGTCTGGACGGAGACTCCAGCTCAGACTATGTCAATAACACATCAGATGAGGAAGAGGATGACTTTGATGAGGGGCTTCCAGAGGAGGATGAAGGTGTGACATATTATATACGCTATTGCCCAGAGGATGACAGCTATCTGGAGGGAATGGACTGCAACGATCCTGAATATGTACACCCTGATGGTCGCATGGAGCCACCTCCGGACACAGACGAGTGCCAGGAAGCAGTAGAGGAATGGGTGGAGGGAGAGGACGATGCACAGGGTGATGAAGATGATGATGATGAGGAGGAGGATGATGACGATGATGATGGAGAGGTACGTTGCGAAGTACTCGAGCAGGACTCTGATCAGCAGCTTTATGATGGCAGACCTGAACCTGTCCTTGATCACCACCACCATCAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20981
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085661 Nonsense 94 796 1 13
Genomic Location (Zv9):
Chromosome 7 (position 32203787)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30596129
GRCz11 7 30867279
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCACAGAGACTACCACAGCCACCCGGACAGTCTGGACGGAGACTCCAGCT[C/A]AGACTATGTCAATAACACATCAGATGAGGAAGAGGATGACTTTGATGAGG
Long Flanking Sequence:
AACACGTTTACCACATTTGTTTTAACTTACCATTGTAAACATCATGTTTTACCATGTAAATGTCTAGCTGTATGTGCGTCTTCCTAACTATCAGTGTTTCCTTCTCTTACTAAACTGACTGTTTTTATTGAGTATAAATTGTGAAAAATGCTGTCATACTTACTATACATCTGTCTTTGTTTGATAGGACTGAGGTTTCCAGTGATGATCGTCCTGTGAGTGCTTCTCAATGGCTCAGAGGAAGAGGCCAGGGATCAACAGCGGCATGGCCACAGAGCCTCATGCTCCAGCTCCACGCTCCTGTCCAGCCCCGTACCCTGACCCTGAGCACCCTGAGGAGGAGTATGAAGAGCACCATGACCCCGAGGTGACCCAACACTCTTACCACAACCAAGAAGAGGCAGATTTGACAGACAGCCGACCGACTACGCCCACAACTCCCGACCACGCCCACAGAGACTACCACAGCCACCCGGACAGTCTGGACGGAGACTCCAGCT[C/A]AGACTATGTCAATAACACATCAGATGAGGAAGAGGATGACTTTGATGAGGGGCTTCCAGAGGAGGATGAAGGTGTGACATATTATATACGCTATTGCCCAGAGGATGACAGCTATCTGGAGGGAATGGACTGCAACGATCCTGAATATGTACACCCTGATGGTCGCATGGAGCCACCTCCGGACACAGACGAGTGCCAGGAAGCAGTAGAGGAATGGGTGGAGGGAGAGGACGATGCACAGGGTGATGAAGATGATGATGATGAGGAGGAGGATGATGACGATGATGATGGAGAGGTACGTTGCGAAGTACTCGAGCAGGACTCTGATCAGCAGCTTTATGATGGCAGACCTGAACCTGTCCTTGATCACCACCACCATCAACACTATACAGATCCCCATCAGGAGCAGCTTCCCCCTCCCATTGAAGATCAGGAGGTGAAGGATGTTGAGAGCAGTGAAAGGTACTGTCCCGATCAGGAGGAAGAACCACAGGTTGGAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40922
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085661 Essential Splice Site 452 796 5 13
Genomic Location (Zv9):
Chromosome 7 (position 32215781)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30608123
GRCz11 7 30879273
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAAAAACATCCGGATGATGCAGGCCCAGGAGGCAGTGAGCAGGGTCAAGG[T/G]ACGAAACCCAAGGACCTCAATATTTCCATTTGATTTCAGTGTGGAGTTCA
Long Flanking Sequence:
TTCTGGTTTACGCAAAAAGGATAGATTTCTGTCACACTTAGAATTAGAATGATGGCATAAGGGATTCCTTGGAGGGTTTTATGACGTCCACATTTCCATTTCGCACAAGCAGAATAATCCCAAGCAACACACCCTGCTTTTTCTCATACTCCAGCTTTTCAGTGTCCACAGTATAATTTTATCAGGATTGGACTGAGAACACACATTTATACACTCCACATCTCCATGCAACTTTTCAGCCTGATAAGCTCACGCTCATATACCTTATCTGTCACTGTGAGGTGGTCCATAGAGGAGGTGGCAACACAACAAATAGCTTTAATAATGAATTCTTGATGCTTTCCCTCTAACAGTGCCGGGCCCCTGTGAGCCCGAGGACCTCATTGATGGGATTATCTTTGCCGCCAACTACCTCGGCTCCACTCAGCTCCTGTCGGAGAGAAATCCATCCAAAAACATCCGGATGATGCAGGCCCAGGAGGCAGTGAGCAGGGTCAAGG[T/G]ACGAAACCCAAGGACCTCAATATTTCCATTTGATTTCAGTGTGGAGTTCAAGCGACAACATTTGGATGAAGCGGATGCAGATTTCTCTGTGGAAAATTAGATGAGAGGAGATTTGTTTGTTTACACCCCAGGACTTGTTGACTAATCAGTAGTTATAGGATTATTTTCCCCGGTGTAGGAGTGTAATCCCTCTCCCTCTCAATTGGTTAATGTAGAAAGCACTCCTGCTGCCATGTTACATGGAAAATTTAAAGAGAATTATTGTGTTTTAAGAGAGCATGTGGTGCAGTCAAAGTACTTTTTTCCCCAAAACGCTTTGGATGCTGACCCTCTCCGCAGCAGTTTATGGGTAGACAGAAACAAAATCAGCTCTGTAAACATGCCAATATATTTATGGCCTTTCTTTTTCTTGCATTAGCGGTAGGGGTAGGGGTGTGTAATGAGCATTATCCACAATAATATTACTTTGAACAATGCACAAAGTAATATAAATCACACAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11600
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085661 Essential Splice Site 686 796 10 13
Genomic Location (Zv9):
Chromosome 7 (position 32245868)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30638210
GRCz11 7 30909360
KASP Assay ID:
2259-9012.1 (used for ordering genotyping assays)
KASP Sequence:
CACCAGCCTGGTGGGGCTTCCTCTCGCCACCTGTCAGGGAATCATCAAGG[T/A]GTGCTACTAGGRTTTGGGCTGTCTGTCTGAACACCGGCCAGRAATCCATC
Long Flanking Sequence:
TAGGCCTGTAATTTGTACAAAAACAAAGGTCATTGACAAAAATAAACTTGTTAATGACTAAGTTTTTTACCAAAATGTTACATTTATAAAAAAACAAAACTAATTTCTAACTTCTTTGGAACACATACAGGACACACGGGGGCAAGTTGATGCTATTTTGAACCCTCAAGCTGTCAGTCTCATGTTATCAACTTAGTAAAATTCTTCTCTTAATTGCTTTTTTCTTTTATGGCCTTTTATTGGCAATCTGCTGTAATCCCTCATGTGTCTCTCTCTCCTCCCACAGCTGCAGCTGGAGAAGCAGAAGGGGGAGATTCTGGGCATAGTGATTGTGGAGTCTGGCTGGGGCTCCATCCTGCCCACAGTCATCCTGGCCAACATGATGAATGGAGGCCCTGCCGCCCGTTCTGGGAAGCTCAGCATCGGTGACCAGATCATGTCAATCAACAACACCAGCCTGGTGGGGCTTCCTCTCGCCACCTGTCAGGGAATCATCAAGG[T/A]GTGCTACTAGGGTTTGGGCTGTCTGTCTGAACACCGGCCAGAAATCCATCTGTGCTATTCTGAGTAGCTGCTTATTAAACCCTAAAACGCAGGTTTTGGAGATGTTAACAGATATGTAATTTATAGGTGGCACATTGCTGAAAACAGTACATTTTATTATCAAGTGGATTGTTTTGTGTTTTTTTGAGCCAATAAATGTTTCTTTTAAGTTAAAGGTAAAATATGATGTATGGTGATTAGTCGCCAGGACTGGAGAGTACATTTACAAGTCATCTGATTTTGACAATTTCCCCGCATTTATTAATGAGAAATAGCTATTTTGATCAAGGTCTTGCTTAGTATTAAAAATAAGATATCATTTCATTACTATGCATGATAATGTATATGTTCTGTCTCCTTTATCAGAACTTTCAGAACACTTCAATTCAGAAGTTTGCACGGGGTTCAAGACACTTTAAATCACTGATATACTTGAAACGATATTATAGAATGAACTGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13279
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085661 Essential Splice Site 726 796 11 13
ENSDART00000085661 Essential Splice Site 726 796 11 13
Genomic Location (Zv9):
Chromosome 7 (position 32248230)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30640572
GRCz11 7 30911722
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAGGCCAGACCTCAAGTACCAGCTGGGMTTCAGTGTGCAGAAWGGCATT[G/T]TGAGTATGGAAGAACTCRRAAATGTTGAGATGAGTTGATGAGTTTTATYG
Long Flanking Sequence:
TAGAAAAAGGGGCACTGCGGGCAGCGAGTAAACAAAAGCTGAATATACAGCGGGAGCAGGCAGAAGCGGGACTAAAAATTCAACCCCGCGCAGATTTTATTTTGTTCGGTGTGCATCAGGCCGGAAAAAGCCACAAAACTGTTCTTCTCTCACAGCCGCCATTGCAACCTCACTTACAATATAGTCTCACAGTGTAGGTCACTCTTACTTCTTTTTGCCCTCAAATGAAGAATGAAAAAGAATAACAGGACACTTGACAATTAATGAAGTGACTGCAAAGGCAATGCAATCTTAAATTTCTGTTGTTATGATCCCACTGTAATAATGCAGTGCAGTTGTGATTGTACTGAGCTACTGTATGTTTGGTTTATTTTCATCAGGGCCTGAAAAATCAGGTGCAGGTGAAGCTGAACATTGTGAGCTGCCCTCCTGTGACCACAGTTCTCATTAAGAGGCCAGACCTCAAGTACCAGCTGGGATTCAGTGTGCAGAATGGCATT[G/T]TGAGTATGGAAGAACTCGGAAATGTTGAGATGAGTTGATGAGTTTTATCGTTCTGAGTTTATGTTTTGTCTGGTCTTCCTCAGATCTGCAGTTTGATGCGAGGAGGGATCGCGGAGAGAGGAGGTGTGCGGGTCGGTCATCGTATTATTGAGATAAATGGCCAAAGTGTTGTGGCCACAGCACATGAGAAGATTGTCCAAGCTCTGTCCAATTCCGTCGGCGAGGTAAGCCCTACCGTTCAATTTATTTGGGGTCTTGAAAGTTAAGGATTCAAGAAAGATATTAAAAAAATTACTTTATTCTCAGGAAGGCTGATTATTTTAAAATATTTAAAAATGTAATATACTCCTGTGAAGGCAACAAAGTAACTTCCACAGAAATCCAACTGAATAAACTAGAAGATGAGAAACACTGGATTAAAGAGGTTCTACATTGCATCTATCTTAAGAAACTGAGGCATTGTTTTAAAGGATCACTCAACTCCTTTAATGTCCCATACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17752
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085661 Essential Splice Site 726 796 11 13
ENSDART00000085661 Essential Splice Site 726 796 11 13
Genomic Location (Zv9):
Chromosome 7 (position 32248230)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30640572
GRCz11 7 30911722
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAGGCCAGACCTCAAGTACCAGCTGGGMTTCAGTGTGCAGAAWGGCATT[G/A]TGAGTATGGAAGAACTCRRAAATGTTGAGATGAGTTGATGAGTTTTATYG
Long Flanking Sequence:
TAGAAAAAGGGGCACTGCGGGCAGCGAGTAAACAAAAGCTGAATATACAGCGGGAGCAGGCAGAAGCGGGACTAAAAATTCAACCCCGCGCAGATTTTATTTTGTTCGGTGTGCATCAGGCCGGAAAAAGCCACAAAACTGTTCTTCTCTCACAGCCGCCATTGCAACCTCACTTACAATATAGTCTCACAGTGTAGGTCACTCTTACTTCTTTTTGCCCTCAAATGAAGAATGAAAAAGAATAACAGGACACTTGACAATTAATGAAGTGACTGCAAAGGCAATGCAATCTTAAATTTCTGTTGTTATGATCCCACTGTAATAATGCAGTGCAGTTGTGATTGTACTGAGCTACTGTATGTTTGGTTTATTTTCATCAGGGCCTGAAAAATCAGGTGCAGGTGAAGCTGAACATTGTGAGCTGCCCTCCTGTGACCACAGTTCTCATTAAGAGGCCAGACCTCAAGTACCAGCTGGGATTCAGTGTGCAGAATGGCATT[G/A]TGAGTATGGAAGAACTCGGAAATGTTGAGATGAGTTGATGAGTTTTATCGTTCTGAGTTTATGTTTTGTCTGGTCTTCCTCAGATCTGCAGTTTGATGCGAGGAGGGATCGCGGAGAGAGGAGGTGTGCGGGTCGGTCATCGTATTATTGAGATAAATGGCCAAAGTGTTGTGGCCACAGCACATGAGAAGATTGTCCAAGCTCTGTCCAATTCCGTCGGCGAGGTAAGCCCTACCGTTCAATTTATTTGGGGTCTTGAAAGTTAAGGATTCAAGAAAGATATTAAAAAAATTACTTTATTCTCAGGAAGGCTGATTATTTTAAAATATTTAAAAATGTAATATACTCCTGTGAAGGCAACAAAGTAACTTCCACAGAAATCCAACTGAATAAACTAGAAGATGAGAAACACTGGATTAAAGAGGTTCTACATTGCATCTATCTTAAGAAACTGAGGCATTGTTTTAAAGGATCACTCAACTCCTTTAATGTCCCATACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44668
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085661 Essential Splice Site 773 796 12 13
Genomic Location (Zv9):
Chromosome 7 (position 32248456)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30640798
GRCz11 7 30911948
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAGCACATGAGAAGATTGTCCAAGCTCTGTCCAATTCCGTCGGCGAGG[T/C]AAGCCCTACCGTTCAATTTATTTGGGGTCTTGAAAGTTAAGGATTCAAGA
Long Flanking Sequence:
GAAGAATGAAAAAGAATAACAGGACACTTGACAATTAATGAAGTGACTGCAAAGGCAATGCAATCTTAAATTTCTGTTGTTATGATCCCACTGTAATAATGCAGTGCAGTTGTGATTGTACTGAGCTACTGTATGTTTGGTTTATTTTCATCAGGGCCTGAAAAATCAGGTGCAGGTGAAGCTGAACATTGTGAGCTGCCCTCCTGTGACCACAGTTCTCATTAAGAGGCCAGACCTCAAGTACCAGCTGGGATTCAGTGTGCAGAATGGCATTGTGAGTATGGAAGAACTCGGAAATGTTGAGATGAGTTGATGAGTTTTATCGTTCTGAGTTTATGTTTTGTCTGGTCTTCCTCAGATCTGCAGTTTGATGCGAGGAGGGATCGCGGAGAGAGGAGGTGTGCGGGTCGGTCATCGTATTATTGAGATAAATGGCCAAAGTGTTGTGGCCACAGCACATGAGAAGATTGTCCAAGCTCTGTCCAATTCCGTCGGCGAGG[T/C]AAGCCCTACCGTTCAATTTATTTGGGGTCTTGAAAGTTAAGGATTCAAGAAAGATATTAAAAAAATTACTTTATTCTCAGGAAGGCTGATTATTTTAAAATATTTAAAAATGTAATATACTCCTGTGAAGGCAACAAAGTAACTTCCACAGAAATCCAACTGAATAAACTAGAAGATGAGAAACACTGGATTAAAGAGGTTCTACATTGCATCTATCTTAAGAAACTGAGGCATTGTTTTAAAGGATCACTCAACTCCTTTAATGTCCCATACTGTCTGTCATTGAGAACCTTAATATTTCAGGACCTGCTGGCTAGAATTTCAAAAAGGAAAAAGAGAGACTTTTAGTATTTACTTTACAGTACATCTTCTTCTTCTATATTTACCCATATATTTATTATATCTTTTTATTTAATTAATTAATGTATTTAATTGTAATTTTTTCAATTGGTTTATTTTTTTATCTGTGTCTTGACTCATCTTTGCATACTTATTAAAGG
Associated Phenotype:
Not determined