Busch Lab

ZMP

mars

Ensembl ID:
ENSDARG00000034396
ZFIN ID:
ZDB-GENE-030219-83
Description:
methionyl-tRNA synthetase, cytoplasmic [Source:RefSeq peptide;Acc:NP_956370]
Human Orthologue:
MARS
Human Description:
methionyl-tRNA synthetase [Source:HGNC Symbol;Acc:6898]
Mouse Orthologue:
Mars
Mouse Description:
methionine-tRNA synthetase Gene [Source:MGI Symbol;Acc:MGI:1345633]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa33988 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa40815 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa40814 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa7590 Missense Mutation detected in F1 DNA Not yet available
sa16933 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa33988
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Essential Splice Site 35 922 None 22
ENSDART00000074544 Essential Splice Site 35 913 None 21
ENSDART00000144514 Essential Splice Site 64 942 None 21
ENSDART00000144911 Essential Splice Site 64 951 None 22
Genomic Location (Zv9):
Chromosome 6 (position 58877375)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58980503
GRCz11 6 58974734
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGGAGCTCAGCGGAGTCCGGTGTGAAACTCAGCTGGTGAAACACGAGGG[T/C]GAGTGTGGAGGAAAGTGTGTGTGTGTGTGCCGTGTGGGATTGTGAAGTGT
Long Flanking Sequence:
TATATATATATATATATATATATATATATATTACCGCTTTAAATACAAAATGTTATCGTTAGTAATATGCAACTGAGTCGCGGTGATTCGAGCATTTGCAAGCGGCATCGACCAATTATATCAAGGCGTTTAACACTTTAACCAATGAGCGTACACCACCGTTTACGCCTGCAGTTTTGCATTATGGGTATTGTAGGTTCCACTCAGCATGAATTCTACGCATTTCCCGAGAGCAGATGACATCTAAAAACTACAGTTTCTCTGTACGGCTGCACGTGGTGTGACGCTCGGTTGCATCAGCGGCAATAGATGATCGCTTCAGACCGGTTCTGTTTGCTGTTGTCGGTATATACGGCGTGTCGGTCTGACTTTAGGAGCATAATCGCGGACGGTGAAATGAAGCTGTTTATCGGTGAGGGAAACCCGCACTGCCTGAAGGTGTTGGCGGCGCTGGAGCTCAGCGGAGTCCGGTGTGAAACTCAGCTGGTGAAACACGAGGG[T/C]GAGTGTGGAGGAAAGTGTGTGTGTGTGTGCCGTGTGGGATTGTGAAGTGTTGTGAATGTTTTGTTGTGGTGCTTTTGGTTGAAGTATATTTAGTTTTTGTTATGTCGATACTGTTTGGCAATTTTCAGACTTTGAAGACATTGAGGTAAAGTTTACCGGTCATTTTAACGGTTCCTATAACGTTACGATAACTACAATTATCGATCTGAAATCCCACTCAAACCCATAGCTAATAATAAATCACAAGAAATAAAGTATTGTCAAGTGTCTCTTCGTTATTTCCACAGCTGTACACACATGATAATACTTTAGGTTTTCAGTAAGAATTAAACTAATGTCAATAAACAGTGAAACAGCTGTTTAACTTAGCCTTTAAATGTCATAGGTAGATAGATGGATAGATAGATAAATAGATGGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATGGATAGACAAAGATAGATAGACAAAGATACACAGATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40815
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Essential Splice Site 91 922 3 22
ENSDART00000074544 Essential Splice Site 91 913 3 21
ENSDART00000144514 Essential Splice Site 120 942 3 21
ENSDART00000144911 Essential Splice Site 120 951 3 22
Genomic Location (Zv9):
Chromosome 6 (position 58866869)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58969997
GRCz11 6 58964228
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACAGACGCGACAAACCAGTGGCTGGAATGGGAGGCTACAAATTTACAGG[T/C]GACGATTATTACATTGCACAACATTAAAATAACTTTAGATAGTTAACATG
Long Flanking Sequence:
TAAATAATTTTAGATTGTTTAGGATAGTTTTATAGGGGAGTACATCTGTATAAAGTGTAATAAACACATTACAAGCATAGATACAGTAAAGCAGTCTAACAGTCTTCAGGTACAGAAAAAAAATCAAATGTACATAAAAACTACATGGTTTTTGTTGTATAAATAAGTAAATGCAATTAAATTTAGTTAAAGCCACAAGCATAATATGTCCTTGTGCTCAAATGCTTTAAACTGGCTTAAAATGTTTACACAGACCTTAAAACCACATGCAATTCATAAAGTTTCAGTATTTCATGGTTAAACTGCTTCTAAAACGATTGCAAATCCTTTCATGACCTGATGATATGATCAGGAGTAGCTGTTACAGTATGCCTTTGACTTCAAGCCTGCAGAAAATAACAATGTTAAACGTCTTCACAGATATCTGTTTGACATCAGTGGTCAGAAGGCGACAGACGCGACAAACCAGTGGCTGGAATGGGAGGCTACAAATTTACAGG[T/C]GACGATTATTACATTGCACAACATTAAAATAACTTTAGATAGTTAACATGTACAGCACGTTATCTTTTAAATCATGTTACAGTAACCCTGTCAGATTGGATGGAGCTTTTAAAGGCCTCTTGCTGATATAATAGAGTGACTGGATCAAAACACACACACACACACACACACACACACACACTTTTAATGAGGTTTAATTTCACTTTTGGTTATTATGTAAGTCTGTTTGTTCAAATAACATGTTTTCTAATGCATCAACATTCCATTAGTTTTAATCAGAGCCCAACCCTAAAATCGGAAGGCTCTGGTTGTGTTTACTCTAGTTAGAAGAGTTATTTCAGAAGTATGATGTTCACTGACTGATTTACTGATTTACTCTTATGCAAATTACATTTCTTTTAAAACATGTCCCAAGTGCTGTTTAATAGAGGGAAGATGATTTGAACACATTTTTGAGCATAATAGTTTTAATAATTAATTTCTAATAACTGTTTGTTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40814
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Essential Splice Site 430 922 11 22
ENSDART00000074544 Essential Splice Site 430 913 11 21
ENSDART00000144514 Essential Splice Site 459 942 11 21
ENSDART00000144911 Essential Splice Site 459 951 11 22
Genomic Location (Zv9):
Chromosome 6 (position 58852038)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58955166
GRCz11 6 58949397
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTATTAAATTGAACAATAACATTGTGTGTGTGTGTGTGTGTGTCCTGCA[G/T]AATCCTCAGTGTAAGGTGTGTAAGGAGACGCCGGTGATTCGCTCCTCCAA
Long Flanking Sequence:
TGTGTGTCTGAAAACGGCACACATGTGGAGTAAACGCTCATCTCAGTCAAACATTTTATGCATGTTATAGTTGTCATTCTTGTCAAATTTTGCATTGAGCTGACAATTTAAAAAAAATATTTTTTATTATTATTTGATATAAATAACTCCTATATAATATGATATTATTGATTAATTATATAATATATGAAAACTATTTAGATTTTCAAAAAGAATAAAAAGATACGTGTTATATTTACTGTGTAATATTTTATGTCACAAAATAAATGAAAATAAATATTTATTACTTGTGTACTAAAAAATAGTGTTATTTAAATTAATAACGATAATATTTAAAATAATTAATGTTTGTTTTAATAGAAATATGTATTTCAATTCTTTCATATTTTATATTTGTATAATTTTTTAATTGTATTTTACATTTTTTATGTCACAAATAAATTAAAAACTATTATTAAATTGAACAATAACATTGTGTGTGTGTGTGTGTGTGTCCTGCA[G/T]AATCCTCAGTGTAAGGTGTGTAAGGAGACGCCGGTGATTCGCTCCTCCAAACACCTGTTCCTGAACCTGCCGAAGGTAAAACTGCTGTGTGTGTGCGTACATCTAAGTCTTCAGCTCCTCCTTAGTGTGTGTGCGTGAGTGGGCTTGCATGTGTGTGTGCATTTGTCTGTTTGCTGCTCATCCTCAGTGTGTGTGTGTGTACGTGAGTGTGTTCATATTCAAGTCTTCAGCTCATCCTCAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTTTGTGACAGCTGGAGCAGGATCTAGAGCAGTGGCTGCAGACGTCGACGGCTGCTGGAGACTGGACCACTAATGCTCGTCACATCACTCGCTCCTGGCTGCGGGACGGTCTGAAGCCGCGCTGCATCACACGTGACTTGAAGTGGGGGACGCCGGTGCCGCACCCCGACTACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7590
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Missense 495 922 12 22
ENSDART00000074544 Missense 495 913 12 21
ENSDART00000144514 Missense 524 942 12 21
ENSDART00000144911 Missense 524 951 12 22
Genomic Location (Zv9):
Chromosome 6 (position 58851579)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58954707
GRCz11 6 58948938
KASP Assay ID:
554-4254.1 (used for ordering genotyping assays)
KASP Sequence:
CATCACTCGCTCCTGGCTGCGGGACGGTCTGAAGCCGCGCTGCATCACAC[G/A]TGACTTRAAGTGGGGGACGCCGGTGCCGCACCCCGACTACAAGGAGAAGG
Long Flanking Sequence:
TTGAACAATAACATTGTGTGTGTGTGTGTGTGTGTCCTGCAGAATCCTCAGTGTAAGGTGTGTAAGGAGACGCCGGTGATTCGCTCCTCCAAACACCTGTTCCTGAACCTGCCGAAGGTAAAACTGCTGTGTGTGTGCGTACATCTAAGTCTTCAGCTCCTCCTTAGTGTGTGTGCGTGAGTGGGCTTGCATGTGTGTGTGCATTTGTCTGTTTGCTGCTCATCCTCAGTGTGTGTGTGTGTACGTGAGTGTGTTCATATTCAAGTCTTCAGCTCATCCTCAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTTTGTGACAGCTGGAGCAGGATCTAGAGCAGTGGCTGCAGACGTCGACGGCTGCTGGAGACTGGACCACTAATGCTCGTCACATCACTCGCTCCTGGCTGCGGGACGGTCTGAAGCCGCGCTGCATCACAC[G/A]TGACTTGAAGTGGGGGACGCCGGTGCCGCACCCCGACTACAAGGAGAAGGTCTGAGATCAACTGCATCCACACCGGGACGCACAACACACTGACTCCTGTATGCAGCTGAAGTCAGAGTTATTCGCCCTCCTGTAAATTACTTTAAATTCTGATGTTGAACAGATTCAGGAATTTCTCACACCTGTGTTCTTCTGGAGAAAGTCTGATTTGTTTTAATTCAGCTGGAATAAAAGCAGTTCTTAATTTTATTAAAAGCATTTTAAGGTCAATATTATTCGCCCCCTTAAGCGTCTTAATGTTTACGTGAAGCAGATTTTGAGATGTTTATTTCAGTAAGTTGATGGATTTATGGGGCACTCCCATATATGAGCAATATCACACGAAATGCCATCCGTCCGAGATTTCTCACCAGACTGCTGTTGTGTTTGCGATAAGGAGGGACAAGGCTGAATCTAGTTTCTTATGGCTCGTTTCTACTGACTGGTACGGTTCGGGTCGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16933
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Essential Splice Site 822 922 19 22
ENSDART00000074544 Essential Splice Site 822 913 19 21
ENSDART00000144514 Essential Splice Site 851 942 19 21
ENSDART00000144911 Essential Splice Site 851 951 19 22
Genomic Location (Zv9):
Chromosome 6 (position 58833973)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58937101
GRCz11 6 58931332
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGAGAAYGAGCAGATCGAGGCTCTGAGGAAGAGATTCGGAGGACTGCAGG[T/C]TTGTAAAGACGTGCATTATTAAYCAGGGCCACAAGAAGRAAATCTGATTT
Long Flanking Sequence:
TGAGGAGCGTTTACTCGCACGTGACCGTTTAGAAGCTTTGCCGTGTGAAAGCGAACCGCACCATCAAGAAAGATAAACATTGTAGCAATTTGAATCCCTGTTTTGGAACAAAACAAAAGATCTACAGGTGTGTAAGCAGCCTTAAATTTGACTCTGTGAACCTCCAGAAACCCTGTTTACACTGAATACTAGTATCTTGCAAAATAGCGTGTAAAATATCACGTACTGTCATCAAGACAAAGACAGAAATTAAGTATTAGAAATTAGTTAGTAAAACGATTAAATTTAAAAATCTCTCAGCACATGGGGAATATTTAAAAATGATTGATTTCACAGCAGGACGAATGATTTCCAGTTGATCTGTACACAGAGTTCAGTCAGCACTGTGAGGATTTTAATTCTGTTACCATGTTTTCCTCTCCTACAGGTCAGTCCTCTGTTCCAAAAGCTGGAGAACGAGCAGATCGAGGCTCTGAGGAAGAGATTCGGAGGACTGCAGG[T/C]TTGTAAAGACGTGCATTATTAACCAGGGCCACAAGAAGAAAATCTGATTTTATTTCAGAACTCTTTATGGAAATGACACAATCCTGAAAACTCATCTGAAAGGCACTATAATGACACACAAGTATAATTAAAAAGCTAAGGAAATTGGGGAGCTAATAAATAAATAAATAGCTATATAAATAAATACAAATGATTAGATGTCTAATGTTTAAAATATCTTAAATATCTGTGTTTGTGTGTATATGTATACACGCACACATATTAAAGTTATGTTTGTGAGTGTATGCACACACACACACCACACACACACACACACACACATGGACAACAAAACCAGTCAAGTGTCCATTTTTGGATCCTGAGATGAATACAAGATCTGGAAGCTGAATAAATAATCTTTCCATTAATGTTTGCTAGGATGAGCAATATGTGGCTGAAAAGCAGCTATGAAAATCTGTAAACTGAGGATTCAACTAATCTAAATATTGAGATAATCACTT
Associated Phenotype:
Not determined