ZMP

ttll3

Ensembl ID:

ENSDARG00000053728

ZFIN ID:

ZDB-GENE-060616-182

Description:

Tubulin monoglycylase TTLL3 [Source:UniProtKB/Swiss-Prot;Acc:Q1ECV4]

Human Orthologues:

RP11-266J6.1, TTLL3

Human Descriptions:

ARPC4-TTLL3 fusion protein [Source:RefSeq peptide;Acc:NP_001185722]
tubulin tyrosine ligase-like family, member 3 [Source:HGNC Symbol;Acc:24483]

Mouse Orthologue:

Ttll3

Mouse Description:

tubulin tyrosine ligase-like family, member 3 Gene [Source:MGI Symbol;Acc:MGI:2141418]

Alleles

There are 4 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa40756	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa15000	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa40756

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000103992	Essential Splice Site	115	771	5	13
ENSDART00000130665	Essential Splice Site	133	789	5	13

Genomic Location (Zv9):

Chromosome 6 (position 40278273)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	6	40349873
GRCz11	6	40347409

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGAGGAGGTCGAGAGGGATGATGAAGCAGAGGATCTGTATGACCTAATGG[T/C]ATGTTTAGACTGTAAAATCCCATTCTAATGACAGTTGAACATTAATCTGT

Long Flanking Sequence:

CATTTATTCATTTTCCTTCGGCTTAGTCTCTATTTCAGAGGTTGCCACAGCGGAATGAACCACCAACTATTCCAGCATATGTGATATATTTTTATTTGTGATATATATTTCTCGAAAATATGCATGCATGTGTTTATTTATGTATACTTAAAAATATACACAGTACACACACATATATATTATGTAAAATTTCATTTTGGATGCAATTCATCACAACACATTTTTATTGTATTCTGCAAATGTTATGTATGGATAATCCATAACATGGCCATAGCATCCCATGCAATGTTTTTAGTTACCGACCTATTGTAATTTAAAGCTTAACATGATAGTTTAAGTAGCTAACTTTACATCGCTCATTCTAACAAACAGATGTCATTGACATTAATCACACTTTAGTCACCTGATCACTGCAACACCACCATCTCCTTTTCTTTATGCAGATTCAGGAGAGGAGGTCGAGAGGGATGATGAAGCAGAGGATCTGTATGACCTAATGG[T/C]ATGTTTAGACTGTAAAATCCCATTCTAATGACAGTTGAACATTAATCTGTGCTTTATGGACACAGTCTTTGATTCTTGTTTGAATTACATAGTCGCGGCTGGTTCGACATGAGACCCCATATTTCTATTGGACTACAAGGAGAGATTCAGTTGATTGCCGATCTTTACGTAAAGAACAGATGACCAATCATTATGCGAAGGCGGGATCGTTCACCACCAAGGTTCATTACAAACTTGACAAATGAATTCTACACAGAAACTCTTTCAGCATTTTGTGTCTGTGCAATTTTCAGGTTGGTTTGTGTATGCATTTGAGAAATCTGCAGTGGTTTGATGCAGCAGATCCTGATACATTCTTCCCACGCTGCTACAGACTGGGGGCACAGGATGAGAAACATGCTTTTATTGGTCAGTGCTCTTAATCTGGAAAATACTGTGTCTTTGCTTTATTGTTCCCTATCGGTTGTGTGGTTTCTTTTCATTTAACAGATGACTATTGC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa15000

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000103992	Nonsense	688	771	13	13
ENSDART00000130665	Nonsense	706	789	13	13

Genomic Location (Zv9):

Chromosome 6 (position 40260483)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	6	40332083
GRCz11	6	40329619

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TACCTTCAACCTGTTGCRTTCTTCCAAACCCAACAGAACTTCATCATCCA[C/T]AAAGACTATCCCACACTCAGCCCCAATCAGATYGCCCTCACACACACAGG

Long Flanking Sequence:

GCCATGAGATTGGCTGATTAGATATTTGCGTTAATAAGCAGTTGGACAGGTGTACCTAATAAAGTAGATGGTAAGTGTATCTATACCTTATCAAACCCAAACAAATGAATAATCTAAAGTAAAAATGAACTGCTCAGTTGGTTTGATGTTTGTTTCTTCAGGCAGCAGTAGATGTTCCTCAGTATGTGGGAGTGAATCTTCTCATCGAGGGCACTTCAATCAGACGTCCTCGTGCTCCTGTCCACAAGTCTCTCATTCAGTCTCACCCAGAGCCGCTATCAAAATCCACCAATCACAAGTCCTCGCTCTTAAGCAGCCCCTGCACTTCTGGCAAGGAAAATCAGTCAGAAGAGATGAAAAGGGCCTGTCCTAACCTTCCCAACCGTAAAATCACAATGGACCAATCCCTGATCTTTCACCCTAAAAGGAAACGCCCCCACAGACTAGTCTTACCTTCAACCTGTTGCGTTCTTCCAAACCCAACAGAACTTCATCATCCA[C/T]AAAGACTATCCCACACTCAGCCCCAATCAGATCGCCCTCACACACACAGGACACGCAGCAACCTTCCAACTCTCTACCGTCCAACTCCATCAGTGGAGGTGATCAACATTCGACCCCGACAAGCTCTCACCTCCAGTCACTACATCCATAAAATACACACAGTCAACCTATCTTACCCAGTGTTGCGCATGCAGCAAAACCACAGGCGATCCAAAAACACGTTTGCAGAGAGAGAAGGGCCAAAGTCATCCTGAGGGAACTTTTTTATCAATTCATATGACCTAAATAGAGCAAATACATTTTACACCGCATCAGTTGTGTTGTGGGTTTATCTTTCAATGCTCTGGATTCAACATCTCTATATGTTATTAATCTACTCTCAGAAAGGGAACAGCATATACTGTAGATTCAAGAAGAGCACTCATGCAGATTTATACCAATTAAGAGCATGTTTATTAAGGATAAATCATTTACTTATGCCTCATGCTTTTCCAAATCCT

Associated Phenotype:

Not determined