Busch Lab

ZMP

dock7

Ensembl ID:
ENSDARG00000078675
ZFIN ID:
ZDB-GENE-050302-15
Description:
Dock7 protein [Source:UniProtKB/TrEMBL;Acc:Q4QRD5]
Human Orthologue:
DOCK7
Human Description:
dedicator of cytokinesis 7 [Source:HGNC Symbol;Acc:19190]
Mouse Orthologue:
Dock7
Mouse Description:
dedicator of cytokinesis 7 Gene [Source:MGI Symbol;Acc:MGI:1914549]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa40719 Nonsense Mutation detected in F1 DNA Not yet available
sa40720 Nonsense Mutation detected in F1 DNA Not yet available
sa20727 Nonsense Available for shipment Available now
sa16309 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa40719
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042134 Nonsense 177 2129 6 49
ENSDART00000065149 None None 319 None 8
ENSDART00000124551 Nonsense 177 295 6 9

The following transcripts of ENSDARG00000078675 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 32028694)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 32349610
GRCz11 6 32336524
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTCCCTGAATAAAATCAGTGATTGCTGTATGTTACAGGATGATTTGAAA[C/T]GAAGGTCCATGTCAATTGATGACACGCCACGGGGCAGCTGGGCCTGCAGT
Long Flanking Sequence:
TATTGCTCTGAATTAAATAATATTAATATTAAACTAAAACAGCCTTTTTAAAACCAGATATTCATTCGTTTGTTAATGCAAGGTTTGAAAGATTTTGTTTAGGCTTTGAAACGTGCCTGAATATTTTTTGTTGCAAATGCTTGTGTGGATATTTGAACAAAAACATTTGATCAGTTTATTTATCAGGTTGCATGCTAATTATCAAACCAATAAAAATGGGTGTATTCTGGATGCACAGGTACCACAAGTTGGGCACAGCATTTAACCCTAACACTTTGGATAAGCAGAAGGAGAGGCAGAGAGGTTTGCCAAAGCAGGTCTTTGAGTCTGATGAGTTGCCAGATCAAAGCAGTTATCAGGACGATCAGGTAAACATTCCTTTACTACTATTATGCTTTTGTTGTTGTTGTTGTTGCTAAGCTCAGTAGAATAATTGCACTGTGTTCTTATGCTCCCTGAATAAAATCAGTGATTGCTGTATGTTACAGGATGATTTGAAA[C/T]GAAGGTCCATGTCAATTGATGACACGCCACGGGGCAGCTGGGCCTGCAGTATATTCGACTTAAAGAACTCTCAGCCTGATGCTCTGCTGCCTCACCTTCTGGATCGAGTTCCAAATGAGGAGATCGACCGCCACAATGAAGACCTGCGCAAGTCAAACCGCCACCGTGAGCTCTTCGCTCTGCATCCTGCTCTTGATGAGGTTGAGTATTAATTTATTTTTTGTTTTATTAGCTCTCACTAATCTAAAAACACGAAAAGATAAATCAGTTAAGTTTATACAATGATCGTTATTAATTTTTTTCCCCATTAATGTAGGAAGAACCCATCGAGCGCCACTGTGTGCCTGATGTTCCAAAAGAACATTTTGGTCAAAGGCTTCTAGTCAAGTGTTTGTCTTTGAAGTAAGTGAGAAACTGCTTTTGTAGACTGATTTGTAATTCTTATCACCACAGTTTTGCTGACATTTTTCTCATTCAAGGTTTGAAATAGAAATTGAGCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40720
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042134 Nonsense 549 2129 14 49
ENSDART00000065149 Nonsense 155 319 4 8
ENSDART00000124551 None None 295 None 9

The following transcripts of ENSDARG00000078675 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 32032257)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 32353173
GRCz11 6 32340087
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCCCGACAGTCGAGTGCGGCCAACAAAAGAGATCCTGGAGTTCCCTGCC[A/T]GAGACGTTTATGTGCCCAACACCACTTACAGGTACAAAGACCCTTTCAGT
Long Flanking Sequence:
TGACGGTCACCAACTTCTTTAAACAGGTCACACTGTTATTCTAAAAAACATCCCAGTATTGATTTTATTCATAGGAAGTTTACAGTCCTTCAGTTTGCAGTCATTACATTGCTAAAGCAATTAAAATAATGCTTTTGAGTTTTTAATAATTAAAGATGTTTTGTTTTTCCGTCATTTATTAGGAAGGAGATCGACTAAGTGATGAAGATCTCTACAAGTTCCTAGCCGACATGCGGCGTCCGTCCTCTGTACTGCGTAGACTGAGGCCCATTACAGGTATAGTTACTATGACGTCTTTAATCAATGGATTTTGACTCTATTGACCCTTTATGTGAAGGCTTGCATAACTTGTTTACTCTATGCCTGTAGCTCAGCTGAAGATCGACATCTCTCCAGCCCCCGAGAACCCGCACTATTGCCTGACTCCTGACCTGCTTCAAGTCAAGCCTTACCCCGACAGTCGAGTGCGGCCAACAAAAGAGATCCTGGAGTTCCCTGCC[A/T]GAGACGTTTATGTGCCCAACACCACTTACAGGTACAAAGACCCTTTCAGTGTATAGATCAGACTCCCAACTCTTTCACGTCATCCACAATCCTATTTAAAGTCCTCCGGTAGCCCTGCTGTATTTTCAAATGGTAAAGTAACTCAAAAACAAAAAAAAACACAATTTGGAATTTTGGAATGTTCAAATTACATACTTTTTATGCAATTATTTTTATTAACTGCACAATATCGTAAAAATCCAACATTGCATTATTTTTTTATTTTGTGATGTATATTGCGATATAAATACAATTTTACCAGGTGACTAGGGCCAGACAGAATCTGCGGACATTTTTTTTTGCATTTTTTTGCATTTCTGCGCAGAATATTGTAAAAAATCTGCAGATTTATGTGGAATGATTTTGGGTGTATCATAACTAAAAACTTATTATGATACATTTATTAATGATACATTAGAAACTTTTATTTAATGTTTAATAAATAATAGTCTACCAATGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20727
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042134 Nonsense 1059 2129 26 49
ENSDART00000065149 None None 319 None 8
ENSDART00000124551 None None 295 None 9

The following transcripts of ENSDARG00000078675 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 32061180)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 32382096
GRCz11 6 32369010
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACATCACTGCACTGGTTAGCACTATTGCTGGTGACATCGTCTCACGTTTT[C/T]AGAAGGTGAGAACATTGCAACTGCATGAATTCCTTGAGCTGTTTTTGTTA
Long Flanking Sequence:
TATTTCAAAATGTTAAAGTTTTAATTGTATTGTCAATCAAAATAAATGCAACCTTGATGAGCGGAATAGCCATCTTTTTAAAGCATTAGTCTTGCTGATCCCAAACCTTTGACCGGTAGTGTACTAAACTATGTGCAAAGTATTTGACGCTGTCTGTGTGTCTGATGTTTTCTTCCTATCCTCAGCTCTTTCATGAGGAGCTCGCCCTGCAGTGGGTTGTCAGCAGTGGCAGTGTGAGGGAGGGAGCCCTGCAACAGGCCTGGTTCTTCTTTGAGCTAATGGTAAGATGTTTCTTCTATGAACGATTAAACAATTTGAATCATTTGTTTTGAGATTGTTTATATAACAAGATGTTTGCATTTTAGGTTAAGAGCATCATCCACCACTTATACTTTACTGACCGTTTGGAGTCTCCCAGGAAAAACCGTTTCCCTGAACGCTTCATGGATGACATCACTGCACTGGTTAGCACTATTGCTGGTGACATCGTCTCACGTTTT[C/T]AGAAGGTGAGAACATTGCAACTGCATGAATTCCTTGAGCTGTTTTTGTTAACTGATTTTAAAATGCTTTTTAAATTTAGTTTATACTTCTGCGTCAAGTGATCGGTGTGACCCATGGCGCATGCACGGAGCATACGTGTGCGCTTGATGAAATATAAATTAGCCTTAACGTAATAATATCATTTCCCAGAGATGGGTTGCGGCTGGGAGGGCATCTGCTGCGTATAAACTTGCTGGATAAGTTGGCGGTTCATTCCGCTGTGGTGACCCCGGATTAATAAAGGGACTGAGTCGAAAATAAAATAAATGAATAATAATATCATTGTTGCTTTAGAAATGTCACATGTACAACAGTATTGTGTTTTTGTTTTATGTCAAAAATCAAAAATTATTTAGCCACTTTGGAAAATCTTTACCATATCTGCTCATCTCTGGTAGCATCTTTCAAGTAGCATCTTAAAACATTAGCATAGGTTATGTTTAATAGGATTGTATAGGAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16309
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042134 Nonsense 1811 2129 42 49
ENSDART00000065149 None None 319 None 8
ENSDART00000124551 None None 295 None 9

The following transcripts of ENSDARG00000078675 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 32081299)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 32402215
GRCz11 6 32389129
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTATTCACGAGGCCAACAGGGATGCTAAGAAGCTTGCCACTATTCATGGT[A/T]AACTTCAGGAAGCCTTTGGCAAAATCGTRCACCAGGTAAATGCTTATGYT
Long Flanking Sequence:
CTTTTTTCTTTCATTTATAATTATAATTATTTATTTATTTATTTTACATTTAAATCAAGATAAGACATAAAATAATCTCATACTTATGCAAATCGCTTCAGAATTGAATAAATATTTCTAACCTGGCTCAGAGGAAGATTGTTAAATGTTCATACAAAACATTGTAAAACCTATAACGCTGTCATATTTCATTTATCATGTTTTGTAAGTGTGACATGCTATTGCAAAACAGGCACCATTTAGGAAACTAGCCTTCCACAGTTATTCAAATATTTACAGTACATCTTAAAATACTTTTGTAATACATTTTGAGTGAAATAAAACATCTGGTCTGCCATCAAATAACTGTATTACATCAGATATTTTGTAGGGCATCAGCCACTCTTATCATCATTTCTCTCCAGGCTGGCATGTACGAAGCGGTCAATGAAGTCTACAAAGTGCTCATCCCTATTCACGAGGCCAACAGGGATGCTAAGAAGCTTGCCACTATTCATGGT[A/T]AACTTCAGGAAGCCTTTGGCAAAATCGTGCACCAGGTAAATGCTTATGTTCAACAAAATCATGCTTAAAATAGATGCTCGGTTTAGCTGAGTGTAAGACAACAAGCGTAAGCAGTGTAAGACAACTGGACTTTGTATGATTGCCCTAGTACTGTAGTACAAAGCAACAATCAGCCAGTTGTCTACATTGGCAACATTTTTGTTGTGTATACAAACAGACGTGAGTTCTGTGTGACACGTGAAAGAGACTTTGAGTTTACATGACTGCGTGACTCTGTTTATCTCTTCATCTGTGAGAGTTCATGGGCAATATCAGTGGAATTCACACCAAGAATGATAACTCTTATTAGCAGCTTTGAGATTTAAAACCACAAGCTGATTTAGCTTGGAATAATTCTAATTTGCTGTCAAAATTTTTTATTGTTCATAAGCGGAGAAAAAAAAAACACTCTAAATATGATTTCAACTATTTTTTGTGATTATTTTTGTGGCTGTTCTGAA
Associated Phenotype:
Not determined