Busch Lab

ZMP

tbx3

Ensembl ID:
ENSDARG00000002216
ZFIN ID:
ZDB-GENE-070209-80
Description:
T-box transcription factor TBX3 [Source:RefSeq peptide;Acc:NP_001095140]
Human Orthologue:
TBX3
Human Description:
T-box 3 [Source:HGNC Symbol;Acc:11602]
Mouse Orthologue:
Tbx3
Mouse Description:
T-box 3 Gene [Source:MGI Symbol;Acc:MGI:98495]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa1334 Essential Splice Site Available for shipment Available now
sa16346 Nonsense Available for shipment Available now
sa26643 Missense, Nonsense Mutation detected in F1 DNA Not yet available
sa18035 Missense, Nonsense Available for shipment Available now
sa40617 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa1334
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006380 Essential Splice Site 215 689 3 7
ENSDART00000122340 Essential Splice Site 215 279 3 4
Genomic Location (Zv9):
Chromosome 5 (position 75418872)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 71537708
GRCz11 5 72322214
KASP Assay ID:
554-1248.1 (used for ordering genotyping assays)
KASP Sequence:
TATTTAAAAATCACGAATATTTAATATAACGTCAGGCTAATTTGTGTTTT[A/G]GACGATACTAAACTCCATGCACAAATACCAGCCAAGATTTCACATCGTGA
Long Flanking Sequence:
CCCCGAAATGCCAAAACGGATGTACATTCACCCCGACAGTCCGGCCACTGGCGAGCAATGGATGTCTAAAGTCGTCAATTTTCACAAACTTAAACTGACAAATAACATCTCCGACAAGCATGGATTCGTAAGTTACAGTCATCAACTCCTATTAATGCATTATGATTAGCATTATTATTGCTGTAAGTATTAGAAGTATTGTGGTTGATATTGATATAGGTGTAATCTTTATACAGTTTATTTGTATTAATCGAAAACACTCGATGCTGTCTGGCAAGCTTCAGTAATAAGAATTTAAACTATTGGATAATTGTTTTTCTTTATTAATACTTTGTATTATATTTCAAATAAATACACGGATGTGTTTGAGCTGGAAAAGATTGTTTAGAGGAGAAAATAAATAAAATGTATTTGATTTGCACCATTCGTAAGTGCAGGATTACTAAATGTTATTTAAAAATCACGAATATTTAATATAACGTCAGGCTAATTTGTGTTTT[A/G]GACGATACTAAACTCCATGCACAAATACCAGCCAAGATTTCACATCGTGAGAGCCAACGACATACTGAAGCTCCCCTACAGCACGTTCAGGACCTACGTGTTCCCCGAGACAGACTTCATTGCTGTCACTGCCTACCAGAACGACAAGGTTGGTCAAAACGAACTTCTGTGTGTTTAAAATGACTGCGATGCATATCGCTGAATGCTTGTTGTAAATGTTTGGAAACCAGAAGAGCAGTCGTTGTTGCATTTCGGTCAAATATAAGCGAGTGTGTTGTTAAATGCTCCAGTGAGGCCTACATCATCACAAAAACTCGCACAGACAGAAAAACACAGAATCGCAGCCGCAGAAATTCAAGTTTGTTAGTGGAAGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTAAAAGAATGAGAAGAGGGAGGAAGGAAGGGAGGACTGCTCAC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa16346
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006380 Nonsense 341 689 5 7
ENSDART00000122340 None None 279 None 4
Genomic Location (Zv9):
Chromosome 5 (position 75420211)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 71536369
GRCz11 5 72320875
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCGYCAGGCTTCATCTCCTGCGGTCTCGACTGCTGGACACAATCATTTA[A/T]AAGGTACGACAGTCAGACAGACATGAGCCGTATGCATTTTCTCCTAGATC
Long Flanking Sequence:
TTAAGCTTATTGTATTTGCACAGAATGACGTAAATAAAAGCTCATGTTCTGTTTAAATGTGATTGCATTTTAGATCACACAACTGAAAATTGACCACAATCCTTTTGCAAAAGGATTTCGGGACACTGGAAATGGGAGACGCGAAAAAAGGTAAAGCTGGGCTCATTTAAAGACTGGACTCTGTTGGTTTTAATAATTGAATCGTGCATTTTCGTCGTAAAACGCGAGGAGAGCGGTGAACTCAAGAACACGCTCTTGTTTGAATCGTCTGTAATACAATTCTGAGTTTGCTTACAGAGGCAATTTCTCTTCTCAATGGCCTGTCTTGGAAATGTGTGTGATACAGGAAGCAGCTGGCTCTGCAATCGATGCGTTCATATGAGGAGCAGCAGAAAAAAGAAAACGGGACGTCAGACGATTCCTCAGGCGAGCAGGCGTCCTTCAAGTGTTTTCGCCAGGCTTCATCTCCTGCGGTCTCGACTGCTGGACACAATCATTTA[A/T]AAGGTACGACAGTCAGACAGACATGAGCCGTATGCATTTTCTCCTAGATCAAAATCGACATTTCTTTTTCTAGAGAATGTCCTTGGAAATGCGACAACAAAAGTAGCCTGCGATTAATTCTGTCCGGGAGACTAAAACAAGTCATTGCTAATTTAAGAGCACGATGATTAGTTTTGTACATGCAGTTATTTAGATGCTGGATGAAAGTGTGCTGCAGGAAGTCTGAGTCTGCTGTCCGCAGTGCACCATATTAGTATTAATGCGTGCGCGTTCTGAGTTGTGCTTTCGCCGTTTAAAACGATATGCATCTCGCTGCTGGTGTTTATAAAAAGTGACACATGTGTGTGTGGTGTAACCTTTCGGTTAGATTCGCATGATTAAACAATGAATGGTCTTACAACTTTCCCGATCTGTGTTGACAGATTTCTGTGACAGCGATGAAGACAGCGATGAAGAAGACAAAGACGCGAACGCAAAAGAAGGGCCAGACTCCAGCAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa26643
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Missense, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006380 Missense 353 689 6 7
ENSDART00000122340 Nonsense 275 279 4 4
Genomic Location (Zv9):
Chromosome 5 (position 75420667)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 71535913
GRCz11 5 72320419
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCGATCTGTGTTGACAGATTTCTGTGACAGCGATGAAGACAGCGATGAAG[A/T]AGACAAAGACGCGAACGCAAAAGAAGGGCCAGACTCCAGCAAAATCTCCA
Long Flanking Sequence:
AGGCTTCATCTCCTGCGGTCTCGACTGCTGGACACAATCATTTAAAAGGTACGACAGTCAGACAGACATGAGCCGTATGCATTTTCTCCTAGATCAAAATCGACATTTCTTTTTCTAGAGAATGTCCTTGGAAATGCGACAACAAAAGTAGCCTGCGATTAATTCTGTCCGGGAGACTAAAACAAGTCATTGCTAATTTAAGAGCACGATGATTAGTTTTGTACATGCAGTTATTTAGATGCTGGATGAAAGTGTGCTGCAGGAAGTCTGAGTCTGCTGTCCGCAGTGCACCATATTAGTATTAATGCGTGCGCGTTCTGAGTTGTGCTTTCGCCGTTTAAAACGATATGCATCTCGCTGCTGGTGTTTATAAAAAGTGACACATGTGTGTGTGGTGTAACCTTTCGGTTAGATTCGCATGATTAAACAATGAATGGTCTTACAACTTTCCCGATCTGTGTTGACAGATTTCTGTGACAGCGATGAAGACAGCGATGAAG[A/T]AGACAAAGACGCGAACGCAAAAGAAGGGCCAGACTCCAGCAAAATCTCCACCACCACCGAGGACTCCAAGGACCAGGACGCGGGTTTGGGCAAGAGTGTGTTCGGCGAGAGCGACTCCTCCTCGGGTCGCAGAAGCGAGAAGACCCGCGCGGACTCTCGGAGCCCCATCACCCTCATCTCCAGCACCACCCGCTCCGGAGAGGAGCTCAAGAGTCCGGTAAGAGAACCGGCCAAGACTACAGACGACTGCCGGACAGTGAGCAAGGAAAATTACATGCCATTGACTGTGCAAACAGACGGCGCAGCGCACTTAAATCAAAACCACTTGCACAATTTCGGATTTCCGCCGGGTTTGGCCGGGCAGCAGTTTTTCAATCATTTGGGTGGTGCCCATCCTTTCCTCCTTCACCCCAGCCAGTTCAACATGGGAGGCGCTTTCTCCAACATGGCCGCAGGGATGGGCCCCATACTGGCCGCGGTGTCCTCTGGTGGAGTAGGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18035
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Missense, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006380 Missense 357 689 6 7
ENSDART00000122340 Nonsense 279 279 4 4
Genomic Location (Zv9):
Chromosome 5 (position 75420679)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 71535901
GRCz11 5 72320407
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GACAGATTTCTGTGACAGCGATGAAGACAGYGATGAAGWAGACAAAGACG[C/T]GAACGCRAAAGAAGGGCCAGACTCCAGCAAAATCTCCACCACCACCGAGG
Long Flanking Sequence:
CTGCGGTCTCGACTGCTGGACACAATCATTTAAAAGGTACGACAGTCAGACAGACATGAGCCGTATGCATTTTCTCCTAGATCAAAATCGACATTTCTTTTTCTAGAGAATGTCCTTGGAAATGCGACAACAAAAGTAGCCTGCGATTAATTCTGTCCGGGAGACTAAAACAAGTCATTGCTAATTTAAGAGCACGATGATTAGTTTTGTACATGCAGTTATTTAGATGCTGGATGAAAGTGTGCTGCAGGAAGTCTGAGTCTGCTGTCCGCAGTGCACCATATTAGTATTAATGCGTGCGCGTTCTGAGTTGTGCTTTCGCCGTTTAAAACGATATGCATCTCGCTGCTGGTGTTTATAAAAAGTGACACATGTGTGTGTGGTGTAACCTTTCGGTTAGATTCGCATGATTAAACAATGAATGGTCTTACAACTTTCCCGATCTGTGTTGACAGATTTCTGTGACAGCGATGAAGACAGCGATGAAGAAGACAAAGACG[C/T]GAACGCAAAAGAAGGGCCAGACTCCAGCAAAATCTCCACCACCACCGAGGACTCCAAGGACCAGGACGCGGGTTTGGGCAAGAGTGTGTTCGGCGAGAGCGACTCCTCCTCGGGTCGCAGAAGCGAGAAGACCCGCGCGGACTCTCGGAGCCCCATCACCCTCATCTCCAGCACCACCCGCTCCGGAGAGGAGCTCAAGAGTCCGGTAAGAGAACCGGCCAAGACTACAGACGACTGCCGGACAGTGAGCAAGGAAAATTACATGCCATTGACTGTGCAAACAGACGGCGCAGCGCACTTAAATCAAAACCACTTGCACAATTTCGGATTTCCGCCGGGTTTGGCCGGGCAGCAGTTTTTCAATCATTTGGGTGGTGCCCATCCTTTCCTCCTTCACCCCAGCCAGTTCAACATGGGAGGCGCTTTCTCCAACATGGCCGCAGGGATGGGCCCCATACTGGCCGCGGTGTCCTCTGGTGGAGTAGGCTCATTGGACGGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40617
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006380 Nonsense 397 689 6 7
ENSDART00000122340 None None 279 None 4
Genomic Location (Zv9):
Chromosome 5 (position 75420798)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 71535782
GRCz11 5 72320288
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGGGTTTGGGCAAGAGTGTGTTCGGCGAGAGCGACTCCTCCTCGGGTCGC[A/T]GAAGCGAGAAGACCCGCGCGGACTCTCGGAGCCCCATCACCCTCATCTCC
Long Flanking Sequence:
AAATGCGACAACAAAAGTAGCCTGCGATTAATTCTGTCCGGGAGACTAAAACAAGTCATTGCTAATTTAAGAGCACGATGATTAGTTTTGTACATGCAGTTATTTAGATGCTGGATGAAAGTGTGCTGCAGGAAGTCTGAGTCTGCTGTCCGCAGTGCACCATATTAGTATTAATGCGTGCGCGTTCTGAGTTGTGCTTTCGCCGTTTAAAACGATATGCATCTCGCTGCTGGTGTTTATAAAAAGTGACACATGTGTGTGTGGTGTAACCTTTCGGTTAGATTCGCATGATTAAACAATGAATGGTCTTACAACTTTCCCGATCTGTGTTGACAGATTTCTGTGACAGCGATGAAGACAGCGATGAAGAAGACAAAGACGCGAACGCAAAAGAAGGGCCAGACTCCAGCAAAATCTCCACCACCACCGAGGACTCCAAGGACCAGGACGCGGGTTTGGGCAAGAGTGTGTTCGGCGAGAGCGACTCCTCCTCGGGTCGC[A/T]GAAGCGAGAAGACCCGCGCGGACTCTCGGAGCCCCATCACCCTCATCTCCAGCACCACCCGCTCCGGAGAGGAGCTCAAGAGTCCGGTAAGAGAACCGGCCAAGACTACAGACGACTGCCGGACAGTGAGCAAGGAAAATTACATGCCATTGACTGTGCAAACAGACGGCGCAGCGCACTTAAATCAAAACCACTTGCACAATTTCGGATTTCCGCCGGGTTTGGCCGGGCAGCAGTTTTTCAATCATTTGGGTGGTGCCCATCCTTTCCTCCTTCACCCCAGCCAGTTCAACATGGGAGGCGCTTTCTCCAACATGGCCGCAGGGATGGGCCCCATACTGGCCGCGGTGTCCTCTGGTGGAGTAGGCTCATTGGACGGGTCCAGCCTGCCCTCGCCCTCACAGAGCCTCACCGGAGCCCCGATGCCGTTTCATCTGCAGCAGCACGTGCTGGCGTCTCAGGTAAGTCCATTAATATTAATGCACAGCAGTGAAAGTCAT
Associated Phenotype:
Not determined