ZMP
pik3r1
Ensembl ID:
ZFIN ID:
Description:
Phosphoinositide-3-kinase, regulatory subunit 1 (P85 alpha) [Source:UniProtKB/TrEMBL;Acc:B0S6V6]
Human Orthologue:
PIK3R1
Human Description:
phosphoinositide-3-kinase, regulatory subunit 1 (alpha) [Source:HGNC Symbol;Acc:8979]
Mouse Orthologue:
Pik3r1
Mouse Description:
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) Gene [Source:MGI Symbol
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| hu7903 | Essential Splice Site | Available for shipment | Available now |
| sa20533 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
hu7903
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040871 | None | None | 727 | None | 15 |
| ENSDART00000056213 | Essential Splice Site | None | 727 | 2 | 16 |
| ENSDART00000122829 | None | None | 449 | None | 10 |
The following transcripts of ENSDARG00000038524 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 55229381)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 54168088 |
| GRCz11 | 5 | 54790924 |
KASP Assay ID:
554-2393.1 (used for ordering genotyping assays)
KASP Sequence:
TTGTTGTTGATGTTGTTCAACGTGTACATTGATTTATCTTCTGTGTTGTA[G/A]GTTTGAATTACTCTTTTTAGATCACTGGGAGCAGGCCTCACACAGATGGG
Long Flanking Sequence:
AAAGATACGCTTCAACTATCTGTCGTGCGGATTCGTTTGCGCTTGGCTAAATTAATCAAACGTTAGTTGGTTTATACCATTGCGCTGGTTAATAATCGTTAAATAATCTGTTAGATAAGTAACGTTACTTTCAAACTTGTGGAGGGTTTTGCTCTGTCAGCATTTCTACATTGGAGTTTCTTCTGCGCCATTTGGTCTTTAATTCGCACTTGTGCAGAAATGTTGTACACTTGTTCTTTTGACGTCGCATTTATGTGTGCGGTGCTACCTAACAATGAAATTTTTTTGTTGTTTGACATGACATCAAGTATTTATACAAAGGTGTAGCCGCAATAATAAAATATTTACATTAGCTCAGTTTGTATTTTGTGGTGAATATACGCATTAGTTTTTATGTTTGCCAAATGTGTTTGTTTTTTGCATCAACGTAGATAAATTGAAGTGATTTTGTTGTTGTTGATGTTGTTCAACGTGTACATTGATTTATCTTCTGTGTTGTA[G/A]GTTTGAATTACTCTTTTTAGATCACTGGGAGCAGGCCTCACACAGATGGGAAGAGTCTGTATGAAGCACCTTGAAGGTGCACCCAATCATTGGACTATCAGTTTCACATAATCTGATGTTGCAAACAGACTGTCAAGTGTGGATGGGGATGAAAATAAAGGCTTTAAGTCTTTGGATAAAATCTTTTAACTTATTTGACTCTCAAATAAGTAGTGGTTCTGATTGATAGTTGATAGTTTTTGTGACAACACAAAAGTTGGAAACAACAGCGTCAAAATGAGTGCAGAAGGATATCAGTACAGAGCACTGTATGACTATAAGAAGGAGAGGGAGGAGGATATTGACCTGCATGTAGGGGACATTCTTACAGTCAATAAAGGTGCATTACTTGCACTTGGCTACATGGAGGGAATGGAGGAGAGACCAGATGAAGTTGGTTGGCTGCCTGGCTTTAATGAAACCACCCAGGAAAAGGGGGACTTTCCTGGAACGTATGTTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20533
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040871 | Nonsense | 498 | 727 | 11 | 15 |
| ENSDART00000056213 | Nonsense | 498 | 727 | 12 | 16 |
| ENSDART00000122829 | Nonsense | 220 | 449 | 6 | 10 |
The following transcripts of ENSDARG00000038524 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 55209057)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 54147764 |
| GRCz11 | 5 | 54770600 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAGGACTGCTATTGAAGCTTTTAATGAGACCATTAAGATCTTTGAAGAG[C/T]AGTGCCAGACGCAAGAACGATACAGCAAAGAATATATTGAGAAGTTTAGA
Long Flanking Sequence:
ACTATCGAACTGAGTCTCTCGCTCAATACAATCCCAAACTAGATGTGAAACTACTGTATCCTGTGTCCAAGCACCAGCAGGTAATTATTGTCCAGTTTAATAGCATCTTGTGAAGAACTTTGCTGGTTTACGATTTAAAATATATATTTAAAAATGGTCTTATTTAACTTTTGCTTGATCATTTTTATTTATAGGATCAAGTGGTAAAAGAGGACAACATCGAAGCTGTCGGAAAGAAGTTGCACGAATACCACCAGCAGTTCCAAGAAAAGAACAGAGAATATGACCGACTCTATGAGGAATACACTAGAACATCACAGGTTTGTTCCAATTAAATATATTTATAGTAGATAATTGACTATATGTGTTTGAATAAAATGATCATGTAGAGTTTGAAATAGACTTTGCATTCTAAGATGCTTTTGTCTGCTCACTAGGAAATACAAATGAAGAGGACTGCTATTGAAGCTTTTAATGAGACCATTAAGATCTTTGAAGAG[C/T]AGTGCCAGACGCAAGAACGATACAGCAAAGAATATATTGAGAAGTTTAGAAGAGAAGGCAACGAGAAGGAAATCCAAAGGTGAGTCTTGATACTGTAAAAATTCAAAGTCTTTTGGAGAGAGTTTCGGTTTAATGCAATGAAGTTTCATGTAATTTTTCTGCAAATATTTCATCATAGGATCATGGTCAATTATGAGAAGTTAAAATCTCGCATCAGTGAAATAGTAGACAGTAAACGACGTCTCGAAGAAGATCTGAAGAAGCAGGCAGCAGACTACAGAGAGATCGACAAGCGGATGAACAGCATTAAGCCTGACCTCATCCAGCTTAGAAAGACCAGGGATCAGTACCTCATGTAAGTACTTTGTCCTCCATAGGTTTTGTGCTAAAAACACAGTTTATTTCATGGACAGTGTTGTAATTTGCTAAATGTTTCTCTTTTGTTGCTGCACAGGTGGTTGACACAGAAAGGAGTCAGACAAAAGAAACTCAACGAATGG
Associated Phenotype:
Not determined