ZMP
si:ch211-1o14.5
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to vertebrate rho/rac guanine nucleotide exchange factor (GEF) 18 (ARHGEF18) [
Human Orthologue:
RP11-428C6.1
Human Description:
Rho-guanine nucleotide exchange factor [Source:UniProtKB/Swiss-Prot;Acc:Q8N1W1]
Mouse Orthologue:
Rgnef
Mouse Description:
Rho-guanine nucleotide exchange factor Gene [Source:MGI Symbol;Acc:MGI:1346016]
Alleles
There are 8 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa26519 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa20469 | Nonsense | Available for shipment | Available now |
| sa40486 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa26517 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa16048 | Nonsense | Available for shipment | Available now |
| sa40485 | Essential Splice Site, Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa26519
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085086 | Nonsense | 23 | 944 | 1 | 24 |
| ENSDART00000133170 | Nonsense | 318 | 1326 | 7 | 25 |
Genomic Location (Zv9):
Chromosome 5 (position 36493654)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 34275603 |
| GRCz11 | 5 | 34875756 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAGTACAAAGTCAGCCGCACATTCAGCTTCATAAAGAGCCGAATGTA[T/G]AGCACTCGCAACAAGAACAAGGTAAATATTGCATACAGTACATGAAATAC
Long Flanking Sequence:
CGAAGAATGTTTACAGGTATTTGACAAACTGCAAGGTATCGCCCATCCCTAGTTGTCGACACTAAAATTTGTAATAACCTTTTTGTTTGTCGCAACTCACAACTCACCCCCCACCAAGCAGAAACGTCCAATCAGGAATGTGTGTAATGCAGAAAATGCCTGCACCGATCAGGTGGAATGTCCTAGTTGTGGCACAGAGGGTGATGACTAATTATTAATTTTCCTGTAGCCTGGAAAAGAATGCATGACTTGGCTTGAAACAAATGCATTAATGAAACCACCGAGGCGCTGCATCGTGGTCTGAGTGAGAGCTGTGTTTTCATTAACACTCACTGGACAGGCATGTGTTTGCGGTAATGAACAGTGTGATTTATTGGATGTGGGCTTGTGTGTTACAGGATTGAGGAAGAAGAATGGGATAAATATATCATCCCTTCCAAAACAGAGTCAGAAAAGTACAAAGTCAGCCGCACATTCAGCTTCATAAAGAGCCGAATGTA[T/G]AGCACTCGCAACAAGAACAAGGTAAATATTGCATACAGTACATGAAATACAAGCAATATATGATTGTATTGTAACAAGAAGATGTAGGGATGTTGTAGTAATACTTTTAATGTTATAAACGTTTTCAGTTTTATCTTTAAACTGTTTTCGTCATTGATGATAAGCAATTTTTTGTCAAGTAAAAGGTCCACATTTCAATGTTATTATTATTTTATTTTTTATTTTTTAATATATATTTGACACTATAACAGATTGTCTGCATTTTTCATTTTTTGTTTCTTTTAAGCCTAAATTCAAACTATAACTATCCAACGTTACATACCCACACCCACCCACAAACCCCTCGGGAGGAATGAGATTCAAATAATAAAACTACACAGGCTCTTTTAAATGTGCACAAAATAAATAATGAGACTATATGTTAAAATATATGCTCTATAGATGTAAACAAGGAGGAAAGATATTTATAACATAAATACAATTCAGGGACATCACTCAGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20469
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085086 | Nonsense | 394 | 944 | 13 | 24 |
| ENSDART00000133170 | Nonsense | 666 | 1326 | 15 | 25 |
Genomic Location (Zv9):
Chromosome 5 (position 36483489)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 34265438 |
| GRCz11 | 5 | 34865591 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTACTTCAAAGAGCTTCAGCAGCAGAACAAGAGATTTCAGCTCTTCATC[A/T]AAGTGAGAGACCCATCAACCAATACTTTATAAGTCGAATATTAATGCATA
Long Flanking Sequence:
AGTGAAACATGCACATCAGATTACAAATTTGCATAATTACAATGCCATTACTGTAACTTTTGATCATCACAGTAAACCATATTGTGTTCAAAGGCACTGTTAGAATAAAACAAGATACCTGCCAACGGGTAACACTATAGCTTGTATTGTGTGTACAAGTTATTGGCATGATTTACATTTCGCATTCTTTTTCAACCCTTAAGACTTATGTGGTGCTTTCATTTTTTAAATTTTTTTTTTGACAGTAAAAAACAAAAGATTCTATTTGATTGATACTGTGTTCTGTAACAGATCTGCCTGTTAGCTTATTTGTCCATGCTAATAAATCACCAATGTGATATAAAAACCTCTCCAACGTGTGTTCGTGTTGATCTCAGTTCTCCCAGGAGAACGCAGAGAAGATGAAGCAGGTGTATGGAGAGTTTTGCAGTCATCACACAGAAGCAGTCAGTTACTTCAAAGAGCTTCAGCAGCAGAACAAGAGATTTCAGCTCTTCATC[A/T]AAGTGAGAGACCCATCAACCAATACTTTATAAGTCGAATATTAATGCATAATAGATGCTTTTGGCAGCACTGAAATTCATTTAACCAATCGCATCTTTTCGGCTCTACAGCAACAGAGTAGTAACTCGCTGGTGAAGAGGCGAGAGATCCCAGAATGTATTTTGTTAGTGACGCAGCGAATTACAAAGTACCCTGTCCTCCTAGAGAGAATACTCCAGTACACAGACGGTAATTTGTCCTTACTGTACAGTAAATGCATGTAAAATCATAACCATACCAGACACATACGTCTATACTTTTTTTTTCTTCTTCAGAGGGCACAGAAGAGCACTCTGACCTCTCTCGAGCTCTAGTCCTGATCCGAGAGCTGATCTCCGCTGTGGACCAATATGTGAGTCAGTATGAGCAGAACCAGAAGCTGAGTGAAGTCTTGGGCCGCATGGAGAACAAGTGCTCTACCAAACTGAAGACCGGCTGCACTTTCCGCAAGCAGGACATCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40486
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085086 | Essential Splice Site | 518 | 944 | 15 | 24 |
| ENSDART00000133170 | Essential Splice Site | 790 | 1326 | 17 | 25 |
Genomic Location (Zv9):
Chromosome 5 (position 36482921)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 34264870 |
| GRCz11 | 5 | 34865023 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGCACCAGGGCCCGCTGCTCTGGAAGACAGCCACTGGAAGACTGAAAGG[T/G]CAGACTGACAACACTTAATACAATATTTAACATAAAAGATATTGTGCATC
Long Flanking Sequence:
CACTGAAATTCATTTAACCAATCGCATCTTTTCGGCTCTACAGCAACAGAGTAGTAACTCGCTGGTGAAGAGGCGAGAGATCCCAGAATGTATTTTGTTAGTGACGCAGCGAATTACAAAGTACCCTGTCCTCCTAGAGAGAATACTCCAGTACACAGACGGTAATTTGTCCTTACTGTACAGTAAATGCATGTAAAATCATAACCATACCAGACACATACGTCTATACTTTTTTTTTCTTCTTCAGAGGGCACAGAAGAGCACTCTGACCTCTCTCGAGCTCTAGTCCTGATCCGAGAGCTGATCTCCGCTGTGGACCAATATGTGAGTCAGTATGAGCAGAACCAGAAGCTGAGTGAAGTCTTGGGCCGCATGGAGAACAAGTGCTCTACCAAACTGAAGACCGGCTGCACTTTCCGCAAGCAGGACATCACCAGCGGCAGGAATCTGCTGCACCAGGGCCCGCTGCTCTGGAAGACAGCCACTGGAAGACTGAAAGG[T/G]CAGACTGACAACACTTAATACAATATTTAACATAAAAGATATTGTGCATCTATCGCCATTAATGATCTTGGAAATTAGATGGATCTGACTGCATTATATGATCTCTGATCTTCCACAGATGTTCTGGCATTTTTGCTGTCTGATTCACTGGTGTTCCTTCAGGAGAAAGATCAGAAATACATTTTTGCTACTGTGGTTGGTTTCTGGATTTACTGTGCTTTTATCTTCATAATCATACATAAGAGTTCAAATGTTTGGGTCTGTATGATTTTAAAATATATATTTTAAAGGCCCTTTACCAAGACTACATTTTACAGCAATATTTAGAAATATTTTTTATAAGAAATATTAATGGATTTGTATTTTTTCCATTTCTTTTGGATTTCTATTCACCAAAACTGCACTTGCTTAATCAGGGTATCTGTGGGGTCTTAAAAAGTCAAAAAATGTCTTTAATCTCAGGCCTTAAATGGTGCTGTATGTAGGTTTTTGACTCTTCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa26517
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085086 | Nonsense | 552 | 944 | 17 | 24 |
| ENSDART00000133170 | Nonsense | 824 | 1326 | 19 | 25 |
Genomic Location (Zv9):
Chromosome 5 (position 36480518)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 34262467 |
| GRCz11 | 5 | 34862620 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTGTCGTCTTGCTGTATTTGTCAGGACCAGAAGCCTCCAGTGATCTCTT[T/A]GCAGAAACTAATTGTGCGTGAGGTGGCCAATGAAGAGAGAGGCATGTTTC
Long Flanking Sequence:
GTTATGGTGTACAGCAGGGTTTTCAATTGGAGGCAATTTGTTCCGGCCCTCCAAATAGTGTGACCAAGACACCAAAAATAAATTTAGTTTAGGTGAAATATGGCCACTATAGTTACGAAGTGAGGTGCGTCTGTTCAATACAGCACAAGCTCCAGTTGAAGGGTTGAGTCACCTTAAATTAACCTTAGTGGCGTGAGCAGCCAAAAACAGTTGGATTCTTACAGTTGATTGTAAAAGCTTCTCAACGCTGCATTTCTGTTGCATGGAACTGTTTTTTTTACCTGGCCTCCATGACAAACTAATTGAATAGCCCTGGTGTACAGTCACTTTTGATCACTTTAATGCATTTAATGCTAAATAATAGTATTGATTTTTCTTAAAGCATGTGACCTGAAATAGTGTGAAACTATATGAAGTGTAAACATTTGTATGCATTTGTGCAGAATTACATTTGTCGTCTTGCTGTATTTGTCAGGACCAGAAGCCTCCAGTGATCTCTT[T/A]GCAGAAACTAATTGTGCGTGAGGTGGCCAATGAAGAGAGAGGCATGTTTCTGATCAGTGCATCTTCAGCCGGGCCTGAGATGTACGAGGTGCATGCAGCCTCTAAAGATGAACGCAACGCCTGGATGAGACTCATCAGAGAGGCCGTGGAGAAGTGTGTAGTGATGATGCATGTTGTTGCACAGAAATTGAGAGGAGCAGAGTGTGTTCTAATTTTAAACTGTATTTGTTTCGTAAAGTTGCCCTGAAGAGGAGGATGAAACTACAAGTGAGTCAGAAGAGGAAAGGAGAGTCACAGAAGCAAAGGTCCAAAAGATCCACCGGCTGCAAGGTAAAAAAAGCTCACCAGCTGTGCTGATGAATCCAAGGAGGTTTAGAATGGATGAAATTTATAATTTAGAATAACTAGCAGTATTGCTACATTAGCATTGGTATTTATCTCGGTTTATCTCAAATTACTTTGCTAGTACAGGCCAATACTTTGGATTTGCAGCAAAATTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16048
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085086 | Nonsense | 672 | 944 | 20 | 24 |
| ENSDART00000133170 | Nonsense | 947 | 1326 | 21 | 25 |
Genomic Location (Zv9):
Chromosome 5 (position 36477124)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 34259073 |
| GRCz11 | 5 | 34859226 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGTGATGGCAGGCCAGCGAGAGGCAGGACCAGAGCCCAGGCTGCTGGTA[C/T]GACCCAGCACTGAAGACRTTCCCCAGGCKGGAGTACTACTCAGCGCCGCT
Long Flanking Sequence:
TTTATGGTTTTCTGGGATGTCTAACAGTATTCAAGTAGAGAAATCAATTGTAAAATAACATGGTCATCATTGTATAAAAATGTTTAAAAAACATTTAATAATATCTTTATCTTTTCATCTTTAATAAATAATCTAAATCTGCAATGTTACTGTTGCAGATACACACATTGTGAAATCAATGCTTAAATTCTATATTGTTCAGCCCTAATTCATATATTTTCTTAATCACATGGGATGGAGACAATGCTTTGTTGATTACTGATTTATGTGATATTAGAATTTTGTTCTTTAGATAAAAACGTAGCCGGTAGAGGTACTCCTGTTTTGTTTATACTTTTTAACAAATTGAACATGACATCCATCACTTTTCTTCCACAGAGACGCTGTGTGGCCATGATCACCTCATCTGTTCCAATCTGGAGGAGAAGCTGCACATCTATGCCGAGCTGTCAGTGATGGCAGGCCAGCGAGAGGCAGGACCAGAGCCCAGGCTGCTGGTA[C/T]GACCCAGCACTGAAGACGTTCCCCAGGCTGGAGTACTACTCAGCGCCGCTCTCAGAGAGGGTGAGTCTGCTCATTCGTCATCAGGTGTACATTAATGGATCAAACATAACAGCAAAACATTTGTAATTCTAAAAAAGGCTACAGTTGTAATATTCAAGTGTTGTTTGTCTATTTTTGACAAAAAGAAATTATATTTTTTTAGTTTATTTCAGAATAGTGTTACTTGATAAGAGTGATACAAAATATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATACAGTTGAGGTCAGAATTATTAGCCCCCTGTTTTTTCCCCCCCTATTTTTGTTTAACAGAGAGAAGATTTTTTCAAAACATTTCTAAACATAATAGTTCTAATAACTTTGAATAATAAGTCATTTAAGGACTAATTTATTTTATTTTTGCCATAATTACAGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40485
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site, Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085086 | Essential Splice Site | 782 | 944 | 23 | 24 |
| ENSDART00000133170 | Splice Site | None | 1326 | None | 25 |
Genomic Location (Zv9):
Chromosome 5 (position 36469853)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 34251802 |
| GRCz11 | 5 | 34851955 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAGTTTTGGTGTAATGTTTCATAACTTTCTGTCACTCAGTGTTTTTGTTT[G/A]TTTGCAGGTGAGTCAGAGTGTGCAGAGCTTGACTCAGCTGCTGTACAGTC
Long Flanking Sequence:
AAACACAACCTTTCATAAAATGTGCTACATGAAGCAGATGCCTACCAAAAATATCTATAAATGAAATAAACTGCACTTTTGTTTGCAATAGAAGGGGACACATTGCTGTACAGCACAAACATAAGGTTACACTTTATTTTGAAGATCACCTTTTAACATTTTGTTGACTATGAGTAACTTTGCAATGATATGTTAACCAACTTTAATTAGAGTCTTAATCAACTGTTATTTTGAGGTTTGAAGAACAAGCTGATGTTTTTGCAAAGGTACTTGTTGAGGGACCATTTAAGATGATTAATCAGACAGTCTACTAATACTCTGACTAATGACTGCTAGTTGCAGAGTTACTTATCATCAGCACCAGTAGTTAAGTTAACCATTACCAGATCAGTCTTTAATTACCAAAATAGATTCTTATTTAATCTGACAAAACAAAAACAAGGCTTTGTTTAGTTTTGGTGTAATGTTTCATAACTTTCTGTCACTCAGTGTTTTTGTTT[G/A]TTTGCAGGTGAGTCAGAGTGTGCAGAGCTTGACTCAGCTGCTGTACAGTCTACAGGTGAGCCAGTGTCACACAACCACATACCAACTCAAGAAATAATTATAGTGGACTGGCCTTGCACCATGCACACATAAACACGCAACATGACTCACTTGTAATAGCTCTGTCTGAGTCTTATATTTCAGTGCCTAAACGTGTTTCTGTGACTTGATCTCTTCTATAACACACTGTAGTTTGGATGTAGAATAGAAGGTGATGTAATGCAGTTGATGTGGAGACTATAGATAGAAGTCACACACCTGTGAATAAACTAGAAGAGATTACAATTTCTGCTTAACAACTTTTTGAATTACTCTTTCAAAAATATAATGGTGTATTCCATTTTTCTAAATTAATTAATTTATTTAATGAGACATGTAATACGTTTCCAAAGAATTTTTCATCAAATAATTTTGATAAATGTTTCTCAAAAAATATTGAGCTGCACAATTGTTTTCCGTAT
Associated Phenotype:
Not determined