Busch Lab

ZMP

man1b1

Ensembl ID:
ENSDARG00000076592
ZFIN ID:
ZDB-GENE-070705-482
Description:
alpha 1,2-mannosidase [Source:RefSeq peptide;Acc:NP_001093449]
Human Orthologue:
MAN1B1
Human Description:
mannosidase, alpha, class 1B, member 1 [Source:HGNC Symbol;Acc:6823]
Mouse Orthologue:
Man1b1
Mouse Description:
mannosidase, alpha, class 1B, member 1 Gene [Source:MGI Symbol;Acc:MGI:2684954]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa14234 Essential Splice Site Available for shipment Available now
sa40449 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14234
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109926 Essential Splice Site 351 632 9 14

The following transcripts of ENSDARG00000076592 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 30827729)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 28589086
GRCz11 5 29189239
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCTGGAGTTCAGAGAGCTCAGCMGACTCACTGGAGACCCCAAATACAAGG[T/G]CAAACACAATTGKTGGTTTTTCTCCARTTCACATTTTTATTATTRAAGTT
Long Flanking Sequence:
TACTCCTTTTATCCTTGGATTTGTCCTATCCTTGCTAAATGAATAAATGTAGATATATTTTGTCGTCAAGAGTTTGCAGAGGCCAGGGAGTGGGTGGCCAAAGAGCTCTCTTTCGATAAGAATGTGGATGTTAATCTGTTCGAGAGCACCATTCGTATCCTGGGTGGCCTACTGAGTACCTACCATCTCACAGGAGACAACCTTTTCCTGGATAAAGCTGTGAGTAAGAAGAAGAGCATGTTGGAGAAAGTCTTCAAACCTCTCCTCCAGTTGATTTGATGTTGTTTTTAACTCCTGAATCATTTTTCAGAAAGAGATTGGCTTCAGACTGATGCCCGCCTTCAGCACTCCCTCCAAAATCCCCTATTCTGATGTGAATATTGGGAAGGGCACAGCTCATCCTCCGCGATGGACTTCAGACAGCACCGTAGCCGAGGTCACTAGCATTCAGCTGGAGTTCAGAGAGCTCAGCCGACTCACTGGAGACCCCAAATACAAGG[T/G]CAAACACAATTGGTGGTTTTTCTCCAATTCACATTTTTATTATTGAAGTTTAGTTTTTAGTTAGTTTTGTTGTTTCTTTGGTTTCTGTCTGTAGCTGGCTGTGATGGAGGTGATGAAGCAGGTGCACAAACTGGATGGAAAGCAAGATGGGCTTGTGCCGATGTTTATCAATACCAACAATGGACTGTTCACCCATCAGGGCATTTACACGCTAGGCGCCAGGGCTGACAGCTACTATGAGTATCTGCTTAAGCAGTGGATACAGGGAGGCAGAATCGAGCAGGAGTGAGTAGAGTCTCTGCGTATTTAGAGTTTGTAGTTTTTGTTGTGTAGTTTCTTATGTAAAAACTGTTAACACTAGTATTTTGCAAAGTGCATCTGTAACAGAATAGATAAAGAGAAATGTTCAAGTCAGGCCTTAAATTTACACTCGACAAGTCCCAAAAGCAAGTTGCAGTCTATATTGCTATTGTTATATATGAAATGTATATAAATGTGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40449
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109926 Nonsense 495 632 12 14

The following transcripts of ENSDARG00000076592 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 30824704)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 28586061
GRCz11 5 29186214
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATATGGAGCTTGCGAAACAGCTGATAGAGACCTGCTACCAGATGTATGCA[C/T]AGATGGAGACCGGTCTGAGTCCAGAAATAGCCCATTTCAACATGCACGAT
Long Flanking Sequence:
TTGTCAATGAACATTTCCTGCTATATGAAGTTGTTATTATTTTATTTCATTGGTTTAACCAGGTTGTGCTAAACCTACACAGGCTTTCCAAGACTATGTGTTCCCAGGAATAGTTGAGAATGTTTTGCATAGTTTAGTGTTGCATGTTCAGTGATTTGTCTGTGCTTCCATGTATTCAGATTGCTGGAGGACTATCTGCAGGCTGTGGAAGGAGTGAAGAAGAACCTGCTGAAGAAATCGACACCTCTTGGCCTTACATTTGTAGGAGAGTTGTCCCATGGACACTTCAGTCCCAAAATGGTATGTCTGTTTTCAGAGAATAAAACCCCCTGCATTTAATCTGAGTCAAACACCTAATGTACCCCATCATCTCTCTCTTTCAGGACCATTTGGTATGTTTCCTGCCTGGCACGTTGGCACTGGGGGTGCATTACGGCCTTCCCGCTGATCATATGGAGCTTGCGAAACAGCTGATAGAGACCTGCTACCAGATGTATGCA[C/T]AGATGGAGACCGGTCTGAGTCCAGAAATAGCCCATTTCAACATGCACGATGGTAGCACACAGGATGTAGATGTGAAGGTGAGCTTAGGAGGATATTTTAGGTGTGTTTACTCTCAGCTGATGTAGGTGAAATAAATCTCTTTGTAATCTTGTAATGTCTTATAGATTGCGGACCGCCACAATCTTCTGCGTCCAGAAACCGTGGAGAGCCTCTTCTACCTGTACAGATTGACCAGGGATAAGAAGTACCAGCAGTGGGGCTGGGAGATCCTGCAGAACTTTAACAAGTACACAAGGGTATGTGATGAAACCGCTCCGCTGTCGTCTTTTTTGTTTTTTAGTACATGCAAAATAGTTGGACAAGATGCTCTGTACTACATCCAAATTTACATGTGTTCCACTCTGATCAGTATTTCACATTCAAATAAGTGTGTAAGGAGTAGTAGTGTCTTGAAAATAGTTCGACCTTGGGTCGACCTTAGAAGCAAGGTGTTTGTAGTT
Associated Phenotype:
Not determined