Busch Lab

ZMP

noxa1

Ensembl ID:
ENSDARG00000056047
ZFIN ID:
ZDB-GENE-050913-32
Description:
NADPH oxidase activator 1 [Source:RefSeq peptide;Acc:NP_001025271]
Human Orthologue:
NOXA1
Human Description:
NADPH oxidase activator 1 [Source:HGNC Symbol;Acc:10668]
Mouse Orthologue:
Noxa1
Mouse Description:
NADPH oxidase activator 1 Gene [Source:MGI Symbol;Acc:MGI:2449980]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa40448 Nonsense Mutation detected in F1 DNA Not yet available
sa31445 Nonsense Available for shipment Available now
sa20441 Essential Splice Site Available for shipment Available now
sa12640 Nonsense Available for shipment Available now
sa2232 Nonsense F2 line generated Not yet available
sa20440 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa40448
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078469 Nonsense 22 269 2 6

The following transcripts of ENSDARG00000056047 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 30790548)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 28551905
GRCz11 5 29152058
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGATCCGCCTGTGGGATGAGGCCGTAAAGGCAATAGACATTCGGGACTG[G/A]CAGGGAGCTCTCAGTAAACTCAACCAGATCACGGATCATAACTGTCGCAC
Long Flanking Sequence:
TCTCTCTCTCTTCAGGGAATGCTGGACTTCCTGATGGCACTGAAACTGGGCGGCACCACAGATGTGTGTCACACTACAAATATTACTTCCCTAAGAGCCCACGCTTAAATACACCTGTTCAGGAGCTGCTCTGATATTCACGAGCAATCACTTCTAGAAAGCAAATTGAGTTCTTGACTTATTTCTGTTTGTTTTGTGTGCAGTGGTAAGTGTCAGTCATTGTATTAGTGTACAGGGCTTTCCTTTCATGGTTTTATTGACTAACAAGAACCTGCATAGCTGGTCTCACTTGTAACAGCTGTTATTCTTACATTCATTAGTGACTGAAGTATAATGTTTTATCAGTACAGCTTGATGATGATTTATTAACCTCTTTTTAAATTTGTGTAGCGTTCTAAAAATAATGTTTGATTATTTGTGTTTTGCTCTAGAGCCATGCTGTATATCGAGTTGATCCGCCTGTGGGATGAGGCCGTAAAGGCAATAGACATTCGGGACTG[G/A]CAGGGAGCTCTCAGTAAACTCAACCAGATCACGGATCATAACTGTCGCACTATGTTTGTGGTTGCGTCCACTCACATCGCCCTGGGTCAAGTGGATTTGGCCATTAAGGTACAAGCTACACGAACTGTCATAGAATTGTTTGATATCAATGACACTAAACAGTTATCTGTTTGTTTGTTGGTAAACTGCATTTGTGTTATTCAGGGGGTTTTAGACTTTAAGATGCAAGACCACCATCTTAAAATTTAAAAGGCAGTTTACATGTATAAAGACCTAGTTTTTAGTGTAAAATGTATCACTTAAGTTGATAAATGGGTGTAAATTTTAAGTTGGATTTTTATTTATTTTGTTTGTTTATTTTTTGTTTTGTTTTAATGTTATTCTATAACGTTTTACTACATTTCTGTTACATTGAATTATTTATTTCATCAGTTGTTGTATTTTTTTTTCATTTTTTTGTATTATTTATTTCACTTGTTTATTTAATTAAAGGGGTAGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31445
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078469 Nonsense 109 269 4 6

The following transcripts of ENSDARG00000056047 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 30787818)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 28549175
GRCz11 5 29149328
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATTGTATTTGGGCTCAGAAATACATGAGGGAAAACCCTGTCATTGACTA[C/A]AAGCAGCTGGGTCTTCGCTATAAACTCTACAGCTGGCAGGTCAGAGCATA
Long Flanking Sequence:
AATGATATATCATTGTTATACAAATTACAATTTAATAGGACTATGACAATTGTAAAAACTAGAAAAACTGTAGAAAAATAAAATGTGTCAAACAAAAAGTGGAATTTTATGTGCCTGACAATGTCAAATTATGTTTTTCAGGCTCTCGACCGAGTAATCGCCAAGGACTCATGCCTTGCTGTGGGATTTTTTCAGCGGTCTGCCGTTCATATGATGGCAAACAGGTGAGATTTCTCTGTTTTTCCACTGTAGCTTTCTATGTGTGAGTCGGCTATCGTGCTTGATACAACACAAACATTGACCTCTTTTGTATAAAGCTGATGTTCTGGACAGCTGATTCACTTTCATCTGACACTGCCTCTTTGTTCTCTTGCTCTCTCACTGTCTCGGTCTCTTTCTCTTTCTGTCTCTGTCATTTTTTCTAATGCCAGGCTTGAGGAGGCATTGTCTGATTGTATTTGGGCTCAGAAATACATGAGGGAAAACCCTGTCATTGACTA[C/A]AAGCAGCTGGGTCTTCGCTATAAACTCTACAGCTGGCAGGTCAGAGCATAAGTGTACTTCTGTCAAGAGTATATGAGATAAAACATGATGTTTTTTTTTTTTTTACTCTTTATTTAAATTTTTCATTGAAAAAAAAAAAAAAAACCTTCACACATATAGTACCACCTAAATACTTCCAAGAGAACTTTGATATATGCTCCGTTTCTTGTAAGTACTCACAGTGAATGTAGCTTACTACAAAAAGGAACTCAAAACCCTACCTTGCACCCCACCTATCTAACATCGATCAAAATATTTATGGAAGGTTCATAAAAATTAAATAATAGGCATTGATGAATTACATTTTCAATCATAATATGGAATTTTTTAAATTAGATTTTTTTATACATTTAAAATTGGAGCAAGGTGTACATGGACAATGAAACCAAGATTATTGTAAAATAAATAATGAAATTAATTAATTAATTAATTACCACAATAGTCTTGTAAAAAAATCTAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20441
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078469 Essential Splice Site 168 269 6 6

The following transcripts of ENSDARG00000056047 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 30781731)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 28543088
GRCz11 5 29143241
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGTATCACTGAACATTGTACTCACTTAATGATTCTGTCAATGGCATTTC[A/G]GAGGAAGGATGTTTTGGAGCCTCTTCTGCTTCCTGAGGGTGAAGTGTTTC
Long Flanking Sequence:
AGTGTTAACTTTTTTTTTCTTCAGAATTTGTAGATAAAGTTCAACAGATCAACTATTAAATTATTTTAAAGATAAATAGTTTGTAATGTTATACAGCAAATTACACTTTTGATCTGTTAAATGTGTCCTTGCTGAAGAAAAGCTTACTTTTTTAATAAGAAAAAAAACTTACTGACCCTAAATTCATTAATATTATCTAAATCTTTATTGTTATGGCATGTAATGTGTTCAACTTTTGTTTACAGTGTATGTGTGTGTGCTTGTGTGTGTTTATTAGGTGCTTTATAATGCAGCAGCCGTTCACTCTAGACTGCAACAATGGGACAAAGCTAGGGACATTTTGCTGGCGGCCTCACAGGAGAGAGGAGCAGGCCGGAGCAACCTGATAGACACGGCCCTAGAGGCTATTTCTGTACGTTTTAGAAACCTTTTGATTGCATTTTGCTGATAAAGTATCACTGAACATTGTACTCACTTAATGATTCTGTCAATGGCATTTC[A/G]GAGGAAGGATGTTTTGGAGCCTCTTCTGCTTCCTGAGGGTGAAGTGTTTCGTCCTAGGAAACTTGAGGTGGACCAGCTAAAACCGAGGGACTTCTTGGGTGAAGCAAAGGTGATTCAAATCTTCACGCTGTATTGCAGTTTTAATGCCTGTTCAAGTGCGGAATTTGAATACTGGATAAATATAAATGTTCAAAACCAATTATTACAGACAATATACGATAAGAAAGGGAATGCACCAAGTAAAGGGGTCTCAATGTTTTGCCCTTCAGCTCTCTGCACTTTTGTCTTTTCCAATTACCTAAAGATATAAGTTATTATATATTATCTTCCTCTTTATTTTGTTTTCTTTTTCGTCAAATAAGTTTTTTATTTGGTCGTTGAATAAACTTACAATATTCACAGATTCCAGGATTAGTTTTCTGAAATACCGTACATTTACAAAAACAAACAAAAACAAAAACAAACACTCCAAGCCCAGCCTGTAAGTATACAAAACTGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12640
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078469 Nonsense 199 269 6 6

The following transcripts of ENSDARG00000056047 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 30781635)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 28542992
GRCz11 5 29143145
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTTTCGTCCTAGGAAACTTGAGGTGGACCAGCTAAAACCGAGGGACTTCT[T/A]GGGTGAAGCRAAGGTGATTCAWATCTTCACRCTGTATTRCAGTTTTAATG
Long Flanking Sequence:
CAAATTACACTTTTGATCTGTTAAATGTGTCCTTGCTGAAGAAAAGCTTACTTTTTTAATAAGAAAAAAAACTTACTGACCCTAAATTCATTAATATTATCTAAATCTTTATTGTTATGGCATGTAATGTGTTCAACTTTTGTTTACAGTGTATGTGTGTGTGCTTGTGTGTGTTTATTAGGTGCTTTATAATGCAGCAGCCGTTCACTCTAGACTGCAACAATGGGACAAAGCTAGGGACATTTTGCTGGCGGCCTCACAGGAGAGAGGAGCAGGCCGGAGCAACCTGATAGACACGGCCCTAGAGGCTATTTCTGTACGTTTTAGAAACCTTTTGATTGCATTTTGCTGATAAAGTATCACTGAACATTGTACTCACTTAATGATTCTGTCAATGGCATTTCAGAGGAAGGATGTTTTGGAGCCTCTTCTGCTTCCTGAGGGTGAAGTGTTTCGTCCTAGGAAACTTGAGGTGGACCAGCTAAAACCGAGGGACTTCT[T/A]GGGTGAAGCAAAGGTGATTCAAATCTTCACGCTGTATTGCAGTTTTAATGCCTGTTCAAGTGCGGAATTTGAATACTGGATAAATATAAATGTTCAAAACCAATTATTACAGACAATATACGATAAGAAAGGGAATGCACCAAGTAAAGGGGTCTCAATGTTTTGCCCTTCAGCTCTCTGCACTTTTGTCTTTTCCAATTACCTAAAGATATAAGTTATTATATATTATCTTCCTCTTTATTTTGTTTTCTTTTTCGTCAAATAAGTTTTTTATTTGGTCGTTGAATAAACTTACAATATTCACAGATTCCAGGATTAGTTTTCTGAAATACCGTACATTTACAAAAACAAACAAAAACAAAAACAAACACTCCAAGCCCAGCCTGTAAGTATACAAAACTGCAATAATCAAAACAACTCCTCAAAGCAATGTATTGTAACTAAAAAAGTTACAATACATTGCTTTGGGGAGAAGAATTCCCCATGAAGGGACAAAAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2232
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078469 Nonsense 224 269 6 6

The following transcripts of ENSDARG00000056047 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 30781559)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 28542916
GRCz11 5 29143069
KASP Assay ID:
554-2939.1 (used for ordering genotyping assays)
KASP Sequence:
TTCACGCTGTATTGCAGTTTTAATGCCTGTTCAAGTGCGGAATTTGAATA[C/A]TGGATAAATATAAATGTTCAAAACCAATTATTACAGACAATATACGATAA
Long Flanking Sequence:
TGACCCTAAATTCATTAATATTATCTAAATCTTTATTGTTATGGCATGTAATGTGTTCAACTTTTGTTTACAGTGTATGTGTGTGTGCTTGTGTGTGTTTATTAGGTGCTTTATAATGCAGCAGCCGTTCACTCTAGACTGCAACAATGGGACAAAGCTAGGGACATTTTGCTGGCGGCCTCACAGGAGAGAGGAGCAGGCCGGAGCAACCTGATAGACACGGCCCTAGAGGCTATTTCTGTACGTTTTAGAAACCTTTTGATTGCATTTTGCTGATAAAGTATCACTGAACATTGTACTCACTTAATGATTCTGTCAATGGCATTTCAGAGGAAGGATGTTTTGGAGCCTCTTCTGCTTCCTGAGGGTGAAGTGTTTCGTCCTAGGAAACTTGAGGTGGACCAGCTAAAACCGAGGGACTTCTTGGGTGAAGCAAAGGTGATTCAAATCTTCACGCTGTATTGCAGTTTTAATGCCTGTTCAAGTGCGGAATTTGAATA[C/A]TGGATAAATATAAATGTTCAAAACCAATTATTACAGACAATATACGATAAGAAAGGGAATGCACCAAGTAAAGGGGTCTCAATGTTTTGCCCTTCAGCTCTCTGCACTTTTGTCTTTTCCAATTACCTAAAGATATAAGTTATTATATATTATCTTCCTCTTTATTTTGTTTTCTTTTTCGTCAAATAAGTTTTTTATTTGGTCGTTGAATAAACTTACAATATTCACAGATTCCAGGATTAGTTTTCTGAAATACCGTACATTTACAAAAACAAACAAAAACAAAAACAAACACTCCAAGCCCAGCCTGTAAGTATACAAAACTGCAATAATCAAAACAACTCCTCAAAGCAATGTATTGTAACTAAAAAAGTTACAATACATTGCTTTGGGGAGAAGAATTCCCCATGAAGGGACAAAAGAAAGGGCCCCCATCTTCTGAAATTTTCCAATGTTGCCTTTTTAATATATATCTTGTTCGTTCCAAGTGCAGAGTAGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20440
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078469 Nonsense 234 269 6 6

The following transcripts of ENSDARG00000056047 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 30781530)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 28542887
GRCz11 5 29143040
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCAAGTGCGGAATTTGAATACTGGATAAATATAAATGTTCAAAACCAAT[T/A]ATTACAGACAATATACGATAAGAAAGGGAATGCACCAAGTAAAGGGGTCT
Long Flanking Sequence:
TCTTTATTGTTATGGCATGTAATGTGTTCAACTTTTGTTTACAGTGTATGTGTGTGTGCTTGTGTGTGTTTATTAGGTGCTTTATAATGCAGCAGCCGTTCACTCTAGACTGCAACAATGGGACAAAGCTAGGGACATTTTGCTGGCGGCCTCACAGGAGAGAGGAGCAGGCCGGAGCAACCTGATAGACACGGCCCTAGAGGCTATTTCTGTACGTTTTAGAAACCTTTTGATTGCATTTTGCTGATAAAGTATCACTGAACATTGTACTCACTTAATGATTCTGTCAATGGCATTTCAGAGGAAGGATGTTTTGGAGCCTCTTCTGCTTCCTGAGGGTGAAGTGTTTCGTCCTAGGAAACTTGAGGTGGACCAGCTAAAACCGAGGGACTTCTTGGGTGAAGCAAAGGTGATTCAAATCTTCACGCTGTATTGCAGTTTTAATGCCTGTTCAAGTGCGGAATTTGAATACTGGATAAATATAAATGTTCAAAACCAAT[T/A]ATTACAGACAATATACGATAAGAAAGGGAATGCACCAAGTAAAGGGGTCTCAATGTTTTGCCCTTCAGCTCTCTGCACTTTTGTCTTTTCCAATTACCTAAAGATATAAGTTATTATATATTATCTTCCTCTTTATTTTGTTTTCTTTTTCGTCAAATAAGTTTTTTATTTGGTCGTTGAATAAACTTACAATATTCACAGATTCCAGGATTAGTTTTCTGAAATACCGTACATTTACAAAAACAAACAAAAACAAAAACAAACACTCCAAGCCCAGCCTGTAAGTATACAAAACTGCAATAATCAAAACAACTCCTCAAAGCAATGTATTGTAACTAAAAAAGTTACAATACATTGCTTTGGGGAGAAGAATTCCCCATGAAGGGACAAAAGAAAGGGCCCCCATCTTCTGAAATTTTCCAATGTTGCCTTTTTAATATATATCTTGTTCGTTCCAAGTGCAGAGTAGATACTAATTCTTCAAGCCATAGTTTGGCAGC
Associated Phenotype:
Not determined