Busch Lab

ZMP

lrrc4.1

Ensembl ID:
ENSDARG00000069402
ZFIN ID:
ZDB-GENE-041210-129
Description:
Si:ch211-235l7.2 [Source:UniProtKB/TrEMBL;Acc:A8BBB4]
Human Orthologue:
LRRC4
Human Description:
leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:15586]
Mouse Orthologue:
Lrrc4
Mouse Description:
leucine rich repeat containing 4 Gene [Source:MGI Symbol;Acc:MGI:2182081]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa17055 Nonsense Available for shipment Available now
sa17086 Nonsense Available for shipment Available now
hu3286 Nonsense Confirmed mutation in F2 line Not yet available
sa40278 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17055
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100971 Nonsense 52 666 1 2
ENSDART00000140028 Nonsense 56 858 2 2
Genomic Location (Zv9):
Chromosome 4 (position 18470517)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 19547123
GRCz11 4 19536099
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCGGGCCCCAGGGTTGCCCGACTGATTGCTCCTGCAACAACCAGCTCAGC[A/T]AGGTGGTGTGCACCAGACRTGGGCTCACTCRTGTGCCMCCAGGCWTACCC
Long Flanking Sequence:
GAGGGAAAAAATCTGTTTTGTGATTGCAAAAATTGGACGTGTAAAACCTTTGAGGTAGGTGTTGAGCCTTTCCAAACATTTTTATCCATAAAATATATCCCCCCTTTTACTTTATTCATTATTCCTTGGCCTTTCACTTCTCCTTCGTTACTCAAATACTTGTGACACAACGTTTAGTCTCCAGTTCAGTAAATGGAAAAACAATCTAGAGTGTTGTTTAACCCAGGGTAGGGCTTCATTAGTCAGAGGTGAACCCCTCCCCTTCCCCCGCTTACTACCCCCCACCCCAACCACCATCATCACCCCACGCCCCCCCAGACGATGCTGAATTATGAATGTGCCACATCATGAGTCTCCTGGGGCGGGTAGCTGTGCGTCGAGCCAGGAAAGCCGCCCTGCTCTGTGTCCTGTTCCTCATGGTTCAAGCGTGCGTGGAGGTGGTGGCCGCGGCCGGGCCCCAGGGTTGCCCGACTGATTGCTCCTGCAACAACCAGCTCAGC[A/T]AGGTGGTGTGCACCAGACGTGGGCTCACTCGTGTGCCCCCAGGCATACCCAGCACCACCCGGCACCTAAACCTGATGGAAAACGCCATCGAGTCTGTGCAGGTCGACTCATTCCGCAACCTCCATCACCTAGAAGTGTTACAGCTGGGCCGCAATGCTATCAGACAGATTGAAGTAGGTGCCTTCAGTGGGTTAACCAATCTCAATACTCTGGAACTATTTGATAACAGATTGACTGTGGTGCCAAGTGGGGCGTTTGAGTATCTGTCCAAGCTGAGAGAGCTGTGGCTGAGAAATAACCCCATTGAAAGCATCCCATCGTATGCATTTAACAGAGTGCCATCGCTGATGAGACTGGATCTGGGTGAACTGAGAAAACTGGAATACATCTCTGATGGGGCCTTTGAAGGTCTAGTTAACCTCAAGTATCTCAACCTGGGGATGTGCAACATTCGAGGGGAGATGCCCAACTTCACACCTCTCGTTGGGCTGGAGGAGCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17086
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100971 Nonsense 129 666 1 2
ENSDART00000140028 Nonsense 133 858 2 2
Genomic Location (Zv9):
Chromosome 4 (position 18470749)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 19547355
GRCz11 4 19536331
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTYAGTGGGTTAACCAATCTCAATACTCTGGAACTATTTGATAACAGAT[T/A]GACTGTGGTGCCWAGTGGGGCRTTTGAGTATCTGTCCAAGCTGAGAGAGC
Long Flanking Sequence:
GCTTCATTAGTCAGAGGTGAACCCCTCCCCTTCCCCCGCTTACTACCCCCCACCCCAACCACCATCATCACCCCACGCCCCCCCAGACGATGCTGAATTATGAATGTGCCACATCATGAGTCTCCTGGGGCGGGTAGCTGTGCGTCGAGCCAGGAAAGCCGCCCTGCTCTGTGTCCTGTTCCTCATGGTTCAAGCGTGCGTGGAGGTGGTGGCCGCGGCCGGGCCCCAGGGTTGCCCGACTGATTGCTCCTGCAACAACCAGCTCAGCAAGGTGGTGTGCACCAGACGTGGGCTCACTCGTGTGCCCCCAGGCATACCCAGCACCACCCGGCACCTAAACCTGATGGAAAACGCCATCGAGTCTGTGCAGGTCGACTCATTCCGCAACCTCCATCACCTAGAAGTGTTACAGCTGGGCCGCAATGCTATCAGACAGATTGAAGTAGGTGCCTTCAGTGGGTTAACCAATCTCAATACTCTGGAACTATTTGATAACAGAT[T/A]GACTGTGGTGCCAAGTGGGGCGTTTGAGTATCTGTCCAAGCTGAGAGAGCTGTGGCTGAGAAATAACCCCATTGAAAGCATCCCATCGTATGCATTTAACAGAGTGCCATCGCTGATGAGACTGGATCTGGGTGAACTGAGAAAACTGGAATACATCTCTGATGGGGCCTTTGAAGGTCTAGTTAACCTCAAGTATCTCAACCTGGGGATGTGCAACATTCGAGGGGAGATGCCCAACTTCACACCTCTCGTTGGGCTGGAGGAGCTGGAAATCTCTGAGAACCTCTTTCCCGAAATCAAACCAGGTTCATTCAGAGGACTGTCTTCACTCAAAAAGTTATGGATCATGAACTCTCAAATAGGGCTAATTGAGCGAAATGCCTTTGATGACCTGGCCTCTTTGGTGGAGCTGAATTTGGCCCACAACAATTTAAGCTCACTGCCCCATGACCTCTATACACCACTGAAATACCTGGTGGAACTTCACCTCCACCACAACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
hu3286
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100971 Nonsense 309 666 1 2
ENSDART00000140028 Nonsense 313 858 2 2
Genomic Location (Zv9):
Chromosome 4 (position 18471290)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 19547896
GRCz11 4 19536872
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACCACAACCCCTGGAACTGTGGCTGTGATTCACTTTGGTTAGCACGTTG[G/A]CTGCGAGAGTACATACCCACCAACTCAACATGCTGTGGGCGTTGCCATTC
Long Flanking Sequence:
CTGAGAGAGCTGTGGCTGAGAAATAACCCCATTGAAAGCATCCCATCGTATGCATTTAACAGAGTGCCATCGCTGATGAGACTGGATCTGGGTGAACTGAGAAAACTGGAATACATCTCTGATGGGGCCTTTGAAGGTCTAGTTAACCTCAAGTATCTCAACCTGGGGATGTGCAACATTCGAGGGGAGATGCCCAACTTCACACCTCTCGTTGGGCTGGAGGAGCTGGAAATCTCTGAGAACCTCTTTCCCGAAATCAAACCAGGTTCATTCAGAGGACTGTCTTCACTCAAAAAGTTATGGATCATGAACTCTCAAATAGGGCTAATTGAGCGAAATGCCTTTGATGACCTGGCCTCTTTGGTGGAGCTGAATTTGGCCCACAACAATTTAAGCTCACTGCCCCATGACCTCTATACACCACTGAAATACCTGGTGGAACTTCACCTCCACCACAACCCCTGGAACTGTGGCTGTGATTCACTTTGGTTAGCACGTTG[G/A]CTGCGAGAGTACATACCCACCAACTCAACATGCTGTGGGCGTTGCCATTCCCCTGCACACATGAGAGGCCGCCAGTTGGTCGAGCTGGATCGGGGTGACACCGGTGCAATGCAGTGCTCCGCCCCCTTCATCGCAGATGCCCCAAGAGACCTGAATATTTCAGCTGAACGTGTGGCAGAACTGAAGTGTCGAACAGCCGCCATGTCTGCTGTACGATGGCTCCTACCAAACGGGACAATTCTAACTCATGCATCAAGTCACCCACGGTTAACAGTGCTAAATGATGGGACTTTGAATTTTTCAAATGTACTTGCAGGTGACACAGGCATGTACACCTGCATGGTGTCCAATGCGGCTGGGAATTCCAATGCTTCAGCCTATCTAAATGTAAGTGCGGCTGAGCTTAACACGTCAAACCTCAGTTACTTCACCACAGTCACAGTGGAGGTGCTGAGCCCCACATCTGAAATGCCCAAGCCCAAAACCACCACAACCACAGC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa40278
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100971 Nonsense 568 666 1 2
ENSDART00000140028 Nonsense 572 858 2 2
Genomic Location (Zv9):
Chromosome 4 (position 18472065)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 19548671
GRCz11 4 19537647
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCTAGCAGCAATCATGCTAATTGTATTTTATAAACTACGAAAGAGGCAT[C/T]AACAGAGGAGCACAGTTGCTTCAGCCAGAACTGTGGAGATTATTCCGGTA
Long Flanking Sequence:
TGCTAAATGATGGGACTTTGAATTTTTCAAATGTACTTGCAGGTGACACAGGCATGTACACCTGCATGGTGTCCAATGCGGCTGGGAATTCCAATGCTTCAGCCTATCTAAATGTAAGTGCGGCTGAGCTTAACACGTCAAACCTCAGTTACTTCACCACAGTCACAGTGGAGGTGCTGAGCCCCACATCTGAAATGCCCAAGCCCAAAACCACCACAACCACAGCAGGTGCCAGCACCACCACCACAGCATCGCCTTCAGTCTTTCAGCCAGTTTTTATCTCAACCCCAACAGTCCTGCTTCAGAGCACAGACACTCCACCAAGTCGTCCATCTGTTATACCTGGCTCGAAAGTAACAACAGGAAAGCCGCCCAATCCAGCCAGTACCAGTCTGGATGAGGTGATGAAGACAACAAAGATCATTATCGGTTGTTTTGTGGCAGTAACCTTGCTAGCAGCAATCATGCTAATTGTATTTTATAAACTACGAAAGAGGCAT[C/T]AACAGAGGAGCACAGTTGCTTCAGCCAGAACTGTGGAGATTATTCCGGTAGATGAAGAACTGCCCCCATCGGCTTCTGCTGCCAATATTGCAGATGAGGGGCAACTTTCTCTACCAGAAATAAGGAATCATAACAGTATTTACAAAGCGGACTACACCCACAAGTTTGACTACGGCTACAAACCAAAACTAGAATACAGTACCCATAAGCCCAAGCAAGATTTCAGCATCCATCAACCCAAATCGGACTACAATACTTACAAACCTAAAGCAGACTATATGTACCAACCAACTCTGGAATACAGCTCTCAGAAACTCACGGATTATTCACACAAGTCCTTGCCGGATTACCACGTACACAAAAAACCGGAACAAAGCCCATACAAACATGGATATGGCACCCACAAACCGGACTACAAATCTCATACGCCTAAACCAGACTTCAGTCCGTTCAAAACAGAGTACGGTGTTCCGAAATCAAAAACTGACTACAGTATGCCC
Associated Phenotype:
Not determined