ZMP
dnmt1
Ensembl ID:
ZFIN IDs:
Description:
DNA (cytosine-5)-methyltransferase 1 [Source:RefSeq peptide;Acc:NP_571264]
Human Orthologue:
DNMT1
Human Description:
DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:2976]
Mouse Orthologue:
Dnmt1
Mouse Description:
DNA methyltransferase (cytosine-5) 1 Gene [Source:MGI Symbol;Acc:MGI:94912]
Alleles
There are 6 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa40174 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa40173 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa16282 | Essential Splice Site | Available for shipment | Available now |
| sa40172 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa20150 | Nonsense | Available for shipment | Available now |
| sa40171 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa40174
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021977 | Essential Splice Site | 227 | 1500 | 8 | 34 |
| ENSDART00000078973 | Essential Splice Site | 227 | 1499 | 8 | 36 |
| ENSDART00000128041 | None | None | 200 | None | 9 |
Genomic Location (Zv9):
Chromosome 3 (position 55454620)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 54348346 |
| GRCz11 | 3 | 54602948 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCCTGAAGCTGAGAATGCTGCTAACCTCAAACCTGTGTCTACAGCAAAG[G/A]TGACGCTTCTTTTCACTTCCAATTTGATTTGCCACTTGAATTAATAACTA
Long Flanking Sequence:
ACGATTTTACTTTAGAGTTGGTGTACTTTTTTTAAATTGTGCAGATTTTGTTAATTTGCAGTCTGATATGGTAGTTTTGTGATCAAGATGTATGAATAAATTTTTATTATCATTTTTTTTTTTTTGTTAAATAATTGGGCCTTTATTCTTTCTTTTAATAGCCCAAAACGAAAGTCTGATGAGCTGAATGGAGAACCAGCAAATGGTGACACAGAAATTAAGACTGAGGAAACTATCACTGAGGAGGTCAGGTCGTTTTACAATTCATTGTTATTAAATTCATAAAAATTAATTTAACAGTATATTATTTTGGGGTTTTCAAGGTCCGTGAAGAGAAACGCCTTAAAACAGAAGATGAGAAGTGAGTATAGTGATGTAAAAGTAAAACTTGAAAACAGCCATTTTACAAATGTACTATGAGGTTTATGATCCCTTGTTGTTCCTCTCTCAGGCCTGAAGCTGAGAATGCTGCTAACCTCAAACCTGTGTCTACAGCAAAG[G/A]TGACGCTTCTTTTCACTTCCAATTTGATTTGCCACTTGAATTAATAACTAAACAACATCTTTAACTTGTTTTAGACTCCTCCGCCGAAATGTCCTGACTGCAGGCAGTATCTGGATGATTCAGACCTAAAGTTCTTTCAAGGGGATCCTGATGATGCTGTGAGCTTCCTACACCTATTTTTTTTTTTTTTTAAACCTTAATCTCAAATTAAGTTTTGTATAGGTTAAGTTTTTGTAGTGGCTGTACACTTGAATGATATGTTTGATTTTGTCTATGGTAGTTGGATGAACCAGAGATGTTAACCGATGAGCGTCTCTCCCTCTTTGATTCAAATGAGGATGGTTTTGAAAGCTATGAAGATCTTCCTCAGCACAAGATCACGAACTTCAGGTAAAGAAGAGATGGATGACTCCAAACTGATCAATGTTTTACTTGCCCACCCCCCACTAATGACTTTGCATCACCTCTCGTTTGTAGTGTGTATGACAAGCGTGGTCATC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40173
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021977 | Essential Splice Site | 227 | 1500 | 8 | 34 |
| ENSDART00000078973 | Essential Splice Site | 227 | 1499 | 8 | 36 |
| ENSDART00000128041 | None | None | 200 | None | 9 |
Genomic Location (Zv9):
Chromosome 3 (position 55454619)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 54348345 |
| GRCz11 | 3 | 54602947 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCTGAAGCTGAGAATGCTGCTAACCTCAAACCTGTGTCTACAGCAAAGG[T/C]GACGCTTCTTTTCACTTCCAATTTGATTTGCCACTTGAATTAATAACTAA
Long Flanking Sequence:
CGATTTTACTTTAGAGTTGGTGTACTTTTTTTAAATTGTGCAGATTTTGTTAATTTGCAGTCTGATATGGTAGTTTTGTGATCAAGATGTATGAATAAATTTTTATTATCATTTTTTTTTTTTTGTTAAATAATTGGGCCTTTATTCTTTCTTTTAATAGCCCAAAACGAAAGTCTGATGAGCTGAATGGAGAACCAGCAAATGGTGACACAGAAATTAAGACTGAGGAAACTATCACTGAGGAGGTCAGGTCGTTTTACAATTCATTGTTATTAAATTCATAAAAATTAATTTAACAGTATATTATTTTGGGGTTTTCAAGGTCCGTGAAGAGAAACGCCTTAAAACAGAAGATGAGAAGTGAGTATAGTGATGTAAAAGTAAAACTTGAAAACAGCCATTTTACAAATGTACTATGAGGTTTATGATCCCTTGTTGTTCCTCTCTCAGGCCTGAAGCTGAGAATGCTGCTAACCTCAAACCTGTGTCTACAGCAAAGG[T/C]GACGCTTCTTTTCACTTCCAATTTGATTTGCCACTTGAATTAATAACTAAACAACATCTTTAACTTGTTTTAGACTCCTCCGCCGAAATGTCCTGACTGCAGGCAGTATCTGGATGATTCAGACCTAAAGTTCTTTCAAGGGGATCCTGATGATGCTGTGAGCTTCCTACACCTATTTTTTTTTTTTTTTAAACCTTAATCTCAAATTAAGTTTTGTATAGGTTAAGTTTTTGTAGTGGCTGTACACTTGAATGATATGTTTGATTTTGTCTATGGTAGTTGGATGAACCAGAGATGTTAACCGATGAGCGTCTCTCCCTCTTTGATTCAAATGAGGATGGTTTTGAAAGCTATGAAGATCTTCCTCAGCACAAGATCACGAACTTCAGGTAAAGAAGAGATGGATGACTCCAAACTGATCAATGTTTTACTTGCCCACCCCCCACTAATGACTTTGCATCACCTCTCGTTTGTAGTGTGTATGACAAGCGTGGTCATCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16282
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021977 | Essential Splice Site | 413 | 1500 | 13 | 34 |
| ENSDART00000078973 | Essential Splice Site | 413 | 1499 | 13 | 36 |
| ENSDART00000128041 | None | None | 200 | None | 9 |
Genomic Location (Zv9):
Chromosome 3 (position 55453601)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 54347327 |
| GRCz11 | 3 | 54601929 |
KASP Assay ID:
2259-4164.1 (used for ordering genotyping assays)
KASP Sequence:
TCAGAAAAACCAGGATGCYACRTATGAGGACCTGCTGAACAAAATAGAGG[T/C]ACAMTTTATGGRAGYRTTGAAGTTCTTTGCCACTTGTCCYATTTTAGAAG
Long Flanking Sequence:
GCCTCATTGAGAAAAATGTGGAACTGTACTTTAGTTGTGCTGTAAAGCCCATCTATGATGACAACCCATGCATGGATGGTACGTGCCACTTTCATTACAATGAATACAGATGTTTTTTTATTTATTTATTTCAAATGCATTGTGTATTTGATTTCAAATTGTTCTCAGGTGGGGTTCCTGCCAAAAAGCTTGGTCCCATCAATGCTTGGTGGATCACTGGTTTTGATGGTGGGGAGAAGGCTTTGATTGGCTTCACTACAGGTATGTTTCAAAGCAAAGTTGACTCTTATCCTTGTCCAGTTTTATTATGCATGGCCATTTAACTAGTTTCATTTTCTTTTCGACAGCGTTTGCTGACTATATCCTAATGGACCCCAGTGAGGAGTACTCTGCTATTTTTGCTCTGATGCAGGAGAAGATCTACATGAGCAAAATTGTGGTTGAATTTCTTCAGAAAAACCAGGATGCCACATATGAGGACCTGCTGAACAAAATAGAGG[T/C]ACACTTTATGGGAGCATTGAAGTTCTTTGCCACTTGTCCCATTTTAGAAGTTGTGGGATAACCTGTTATTTGTCTTTTTAGACTACTGTCCCGCCCGCGGGGCTCAACTTCAACCGTTTCACAGAAGACACACTCTTGCGCCATGCCCAGTTTGTGGTAGAGCAGGTCGAGAGCTACGATGAGGCTGGAGACTCTGATGAACAACCCATTATAATCACTCCATGTATGCGTGACTTGATCAAGCTGGCTGGTGTTACTTTGGGCAAGAGGTGAGTTTACTAGAATTGGTGGTCTCTTAAATGCCTTCAATGAGATAACTGGGTAATGGTGGGTTCGATATACTGGTACCCAGAAAGCAGACCTCAAACTGTTCTCTTAGCAACTGAAACCAATTTGTTATTTTATCCTGCATGAGGCATGGGCTTCAATATTGTGGACCATCAGGGAGGGCTATCGGTGTTTCTCATAGGACATATAATGTATTCATGTAGCTTAAACCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40172
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021977 | Nonsense | 563 | 1500 | 16 | 34 |
| ENSDART00000078973 | Nonsense | 563 | 1499 | 16 | 36 |
| ENSDART00000128041 | None | None | 200 | None | 9 |
Genomic Location (Zv9):
Chromosome 3 (position 55452192)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 54345918 |
| GRCz11 | 3 | 54600520 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTCAGCTTGTAAGGATATGATCAAGTTTGGAGGCAGTGGCAGAAGTAAA[C/T]AAGCCTGTCAGAAGAGGAGGTATGCTTACTGTGCAGTCTTTGCTGTTGCG
Long Flanking Sequence:
TCTGAACATCTTTTTTCAGTTTAAATGGGTTTAGTTACTTCAGAGCTGTTTGTCTTAACTCAATCCATTGTGTCTTGTGCATTAAACGCATGGCTCTTTTTTGCTTTTATTTGTGCCCTCTGTATCTTGTTTGCTCTGCTCATGTTTTTTTTTTTTCCCCTGTTCAGGAGAGCAGCCAGAAGACAAGCCGTCCGCCATCCCACTAAGATTGAAAAGGACAACAAGGGCCCGACTAAAGCCACCACCACTAAACTGGTCTACCTGATCTTTGACACATTCTTCTCTGATCAGATTGACCAGAACAATAAGGATGGAGGTGTGAAGAGACAACGGTGTGGTGTCTGTGAGGTTGGTTGTCTGAAAATAGCAGGCACAGTTTAACTGAAATGCAAGCATGATGATTGGCGACCTTGGTATTTCAGGTGTGTCAAGCTCCAGACTGCGGCAAGTGTTCAGCTTGTAAGGATATGATCAAGTTTGGAGGCAGTGGCAGAAGTAAA[C/T]AAGCCTGTCAGAAGAGGAGGTATGCTTACTGTGCAGTCTTTGCTGTTGCGTAATCATTCTCCTCAGCAGTTTTGTATTTTCCATGTGTTTTAAAGGCCTTTCTTTGCTTTCTCTGTTTTTATATTATAATGATTAACATTTTGAATGAGGCTAAATGTCATTCAACAATTAAGGTTTTTAATAGTTTTTACTATTTATAGTGCCAATTTTGTCTATACTCATGCCATTTTAAATTGGCATTTCATTTACCTAGGCATGTATATTTAATTGATCTCAGATTAAATGTTACAATGATATCTAATTGTCTTAAACAACTTCCTAGTTGTTGACCTTTTAGGCCCCGTTTACACTAGTGCGTTTTAGTATTAAAACATCGTTTTAGAATGAAAACGATCCGCGTCCACACTCGCTTTTTACCCAGCGTTTCTGAACTGCTCTCCGTCCACACCAAAATTCTGAAAACGCACATCACATGACCACACACACACACACACACACAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20150
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021977 | Nonsense | 698 | 1500 | 19 | 34 |
| ENSDART00000078973 | Nonsense | 698 | 1499 | 19 | 36 |
| ENSDART00000128041 | None | None | 200 | None | 9 |
Genomic Location (Zv9):
Chromosome 3 (position 55449605)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 54343331 |
| GRCz11 | 3 | 54597933 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCCTTGGAGAGTCATCAGACCCTCTTGAGCTCTTCCTAGTGGATGAGTG[T/A]GAAGACATGCAGCTAAGTTTTATCCATGGCAAGGTCAACGTCTTCTACAA
Long Flanking Sequence:
TGTAGCTGGTAAACTCCTTTTTGTTTCATGGCTTTTGCTGTTTTTGCCTTAGTTTGTCAAGTTGTGCTACTAACCCTTTTAGCTTTCATGTGGCTGGAGACTTTTCTCCCCTCCCAAATTTAGAAGACTTTAAATTTTTATTTTTTTTTTGCCGTCATCTTTTCAGACTGAGGGAAAGAAGGAATATTACATGAAAGTGCGTGTGGAAAATGAGGTGTTGGAGGTGGGAGATTGTGTATCTGTAAGCCCTGATGACCCATCACATCCTCTCTACCTGGCCAGGTAAAATTATCAAAGCAATTTCTTTTGTAAAACCAAAAGGTTTAACATGTTTACTAGACTCTCTAATTAGTAAATCATTGGTTTCTTTAAATTTGTAGGATTACAGCTTTGTGGGATGATGGTGAGAAGATGTTTCATGCCCATTGGTTCTGCCGTGGCACTGATACGGTCCTTGGAGAGTCATCAGACCCTCTTGAGCTCTTCCTAGTGGATGAGTG[T/A]GAAGACATGCAGCTAAGTTTTATCCATGGCAAGGTCAACGTCTTCTACAAGGCACCATCTGAAAACTGGTATATGGAGGTACATACGCCAAAGTGTGGGCAGTGTTTGTGTTTAACAAACTGGGCAGAGGTTTTAACACTGTTATTGTTTTGAAGGGTGGAATGGATGAAGACATCAAAGTGATTGACGATGATGGTGAAAGCTTCTTTTATCAGCTCCATTATGAAGGTGAATGTGCTCGCTTTGAGACTCCTCCCAAGGTCACACCCTCTGAGGACTGCAAGTATAAGTAAGAGCCCCTTTTGACCTATTTTAATGGGACACCTGTTCTGTATTTGTGCTATAAAATGTTATGTTTCACTAGGTTTTGTGCCAGCTGCACCAGAAACAAAGAACGAGAGGCTGAGTCTGTTCCCCATGCCTATGAGCCCTTAGAGGATGAGGAGAGTGACTCTAAAGTCTTCTATGGGTTGGTGAACTATAAGGGAGAGCAGTACAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40171
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021977 | Nonsense | 1016 | 1500 | 25 | 34 |
| ENSDART00000078973 | Nonsense | 1015 | 1499 | 27 | 36 |
| ENSDART00000128041 | None | None | 200 | None | 9 |
Genomic Location (Zv9):
Chromosome 3 (position 55448044)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 54341770 |
| GRCz11 | 3 | 54596372 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAGGGAAAGGGAAAGCAGCGCCTCAAGAACCACAGGATCAGGAGCCA[C/T]AAGAGCCAGTGGTTCCCAAACTGCGCACTCTGGATGTATTCTCTGGCTGT
Long Flanking Sequence:
CTGTCGTGTTGAGTATGCAGAGGATCTGGTTGAAAGTGTGCAGGACTATTCAAACAAAGGACCCGATCGCTTCTATTTCCTTGAGGTAAGGATAAAATCTGGCTGTAATGGAGCTGCCAATGGTACTCGTAATGCAGCTGAAAATATTTTCTGCCATGACTTACCTAATGGTTCTTTTTGTAGGCATACAATGCCAAAACCAAGAGCTTTGAGGATCCTCCCAATCATGCTAGATCTGCTGTGAATAAGGGCAAAGGGAAAGGAAAGGGCAAAGGTAAGTCAAGTGTAATGTTGAAATAAGTAATGGAAACTTCTAGGTATGCTCTTGTGTTTTTTTTAAGCTAAAAATGGTCCATCGTGGATTCAAGATGGCTTAAATATCTGAACACAATCATAACTGCATGTGGGGAGAAATTGCAGCTTAAATGTTTGTACCATGGTTGTCTGTAGGAAAAGGGAAAGGGAAAGCAGCGCCTCAAGAACCACAGGATCAGGAGCCA[C/T]AAGAGCCAGTGGTTCCCAAACTGCGCACTCTGGATGTATTCTCTGGCTGTGGTGGTCTGTCTGAGGGCTTCCATCAAGCAGGTTTGGCTTCCATTGAGTCTCTTTATAGAACCATGTTACACAATGTATTATTACTAGGGATGTAACTGTATTGTAAATACCGTCATACCGCAATATTAATTTTTTTTGATATTACCGAAGTCGCACGACTCAGTAAAACTATAGGTCTTCTGAGAAAATTTGCTCAGGCGAATGAAGCGAACGGGAGGTAGCGAAAACTACAATTCCCATCAGCCCATGCTTGACCATCATCCCTTGCGGTCTGTTGTCGCTACAGATCCAGTAATGCGGAAATAGAGTGTGCTGCTAGAAGCGGGGATGAAAAAAGAGCTGGAAAACTCTAAAGCGGGTGTTGTCGCCGCGTGCGTACTTAATAGCGGTGTTGTCGCGCGAGTTCTTATCAGCTGTGTTGTCGCGCGCGTACTGAATAGCGGTGTTGT
Associated Phenotype:
Not determined