ZMP
dnmt1
Ensembl ID:
ZFIN IDs:
Description:
DNA (cytosine-5)-methyltransferase 1 [Source:RefSeq peptide;Acc:NP_571264]
Human Orthologue:
DNMT1
Human Description:
DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:2976]
Mouse Orthologue:
Dnmt1
Mouse Description:
DNA methyltransferase (cytosine-5) 1 Gene [Source:MGI Symbol;Acc:MGI:94912]
Alleles
There are 6 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa16282 | Essential Splice Site | Available for shipment | Available now |
| sa20150 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa16282
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021977 | Essential Splice Site | 413 | 1500 | 13 | 34 |
| ENSDART00000078973 | Essential Splice Site | 413 | 1499 | 13 | 36 |
| ENSDART00000128041 | None | None | 200 | None | 9 |
Genomic Location (Zv9):
Chromosome 3 (position 55453601)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 54347327 |
| GRCz11 | 3 | 54601929 |
KASP Assay ID:
2259-4164.1 (used for ordering genotyping assays)
KASP Sequence:
TCAGAAAAACCAGGATGCYACRTATGAGGACCTGCTGAACAAAATAGAGG[T/C]ACAMTTTATGGRAGYRTTGAAGTTCTTTGCCACTTGTCCYATTTTAGAAG
Long Flanking Sequence:
GCCTCATTGAGAAAAATGTGGAACTGTACTTTAGTTGTGCTGTAAAGCCCATCTATGATGACAACCCATGCATGGATGGTACGTGCCACTTTCATTACAATGAATACAGATGTTTTTTTATTTATTTATTTCAAATGCATTGTGTATTTGATTTCAAATTGTTCTCAGGTGGGGTTCCTGCCAAAAAGCTTGGTCCCATCAATGCTTGGTGGATCACTGGTTTTGATGGTGGGGAGAAGGCTTTGATTGGCTTCACTACAGGTATGTTTCAAAGCAAAGTTGACTCTTATCCTTGTCCAGTTTTATTATGCATGGCCATTTAACTAGTTTCATTTTCTTTTCGACAGCGTTTGCTGACTATATCCTAATGGACCCCAGTGAGGAGTACTCTGCTATTTTTGCTCTGATGCAGGAGAAGATCTACATGAGCAAAATTGTGGTTGAATTTCTTCAGAAAAACCAGGATGCCACATATGAGGACCTGCTGAACAAAATAGAGG[T/C]ACACTTTATGGGAGCATTGAAGTTCTTTGCCACTTGTCCCATTTTAGAAGTTGTGGGATAACCTGTTATTTGTCTTTTTAGACTACTGTCCCGCCCGCGGGGCTCAACTTCAACCGTTTCACAGAAGACACACTCTTGCGCCATGCCCAGTTTGTGGTAGAGCAGGTCGAGAGCTACGATGAGGCTGGAGACTCTGATGAACAACCCATTATAATCACTCCATGTATGCGTGACTTGATCAAGCTGGCTGGTGTTACTTTGGGCAAGAGGTGAGTTTACTAGAATTGGTGGTCTCTTAAATGCCTTCAATGAGATAACTGGGTAATGGTGGGTTCGATATACTGGTACCCAGAAAGCAGACCTCAAACTGTTCTCTTAGCAACTGAAACCAATTTGTTATTTTATCCTGCATGAGGCATGGGCTTCAATATTGTGGACCATCAGGGAGGGCTATCGGTGTTTCTCATAGGACATATAATGTATTCATGTAGCTTAAACCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20150
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021977 | Nonsense | 698 | 1500 | 19 | 34 |
| ENSDART00000078973 | Nonsense | 698 | 1499 | 19 | 36 |
| ENSDART00000128041 | None | None | 200 | None | 9 |
Genomic Location (Zv9):
Chromosome 3 (position 55449605)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 54343331 |
| GRCz11 | 3 | 54597933 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCCTTGGAGAGTCATCAGACCCTCTTGAGCTCTTCCTAGTGGATGAGTG[T/A]GAAGACATGCAGCTAAGTTTTATCCATGGCAAGGTCAACGTCTTCTACAA
Long Flanking Sequence:
TGTAGCTGGTAAACTCCTTTTTGTTTCATGGCTTTTGCTGTTTTTGCCTTAGTTTGTCAAGTTGTGCTACTAACCCTTTTAGCTTTCATGTGGCTGGAGACTTTTCTCCCCTCCCAAATTTAGAAGACTTTAAATTTTTATTTTTTTTTTGCCGTCATCTTTTCAGACTGAGGGAAAGAAGGAATATTACATGAAAGTGCGTGTGGAAAATGAGGTGTTGGAGGTGGGAGATTGTGTATCTGTAAGCCCTGATGACCCATCACATCCTCTCTACCTGGCCAGGTAAAATTATCAAAGCAATTTCTTTTGTAAAACCAAAAGGTTTAACATGTTTACTAGACTCTCTAATTAGTAAATCATTGGTTTCTTTAAATTTGTAGGATTACAGCTTTGTGGGATGATGGTGAGAAGATGTTTCATGCCCATTGGTTCTGCCGTGGCACTGATACGGTCCTTGGAGAGTCATCAGACCCTCTTGAGCTCTTCCTAGTGGATGAGTG[T/A]GAAGACATGCAGCTAAGTTTTATCCATGGCAAGGTCAACGTCTTCTACAAGGCACCATCTGAAAACTGGTATATGGAGGTACATACGCCAAAGTGTGGGCAGTGTTTGTGTTTAACAAACTGGGCAGAGGTTTTAACACTGTTATTGTTTTGAAGGGTGGAATGGATGAAGACATCAAAGTGATTGACGATGATGGTGAAAGCTTCTTTTATCAGCTCCATTATGAAGGTGAATGTGCTCGCTTTGAGACTCCTCCCAAGGTCACACCCTCTGAGGACTGCAAGTATAAGTAAGAGCCCCTTTTGACCTATTTTAATGGGACACCTGTTCTGTATTTGTGCTATAAAATGTTATGTTTCACTAGGTTTTGTGCCAGCTGCACCAGAAACAAAGAACGAGAGGCTGAGTCTGTTCCCCATGCCTATGAGCCCTTAGAGGATGAGGAGAGTGACTCTAAAGTCTTCTATGGGTTGGTGAACTATAAGGGAGAGCAGTACAAA
Associated Phenotype:
Not determined