Busch Lab

ZMP

adcy8

Ensembl ID:
ENSDARG00000031783
ZFIN ID:
ZDB-GENE-070912-197
Description:
adenylate cyclase type 8 [Source:RefSeq peptide;Acc:NP_001137224]
Human Orthologue:
ADCY8
Human Description:
adenylate cyclase 8 (brain) [Source:HGNC Symbol;Acc:239]
Mouse Orthologue:
Adcy8
Mouse Description:
adenylate cyclase 8 Gene [Source:MGI Symbol;Acc:MGI:1341110]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa38352 Nonsense Mutation detected in F1 DNA Not yet available
sa39913 Nonsense Mutation detected in F1 DNA Not yet available
sa16359 Nonsense Available for shipment Available now
sa39912 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa30826 Nonsense Mutation detected in F1 DNA Not yet available
sa39911 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38352
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087823 Nonsense 80 886 3 17
ENSDART00000134139 Nonsense 75 881 2 16
ENSDART00000137913 None None 312 None 6
ENSDART00000140913 None None 246 None 6
Genomic Location (Zv9):
Chromosome 2 (position 42962709)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 43012173
GRCz11 2 42861591
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCACACTCTCCGCTCAGGAACTTGTTCGAATGCTCAACGAACTCTTTGCA[C/T]GATTCGACCGACTGGCACACGTAAGTAAACACACTTTTACCAGAATGCAT
Long Flanking Sequence:
TCAAAGCCTAAAAGGGGCAGTTTATAAAAAGTTATAACATTATCTGTGGGGTATTTTGAGCTGGAACTTGGCATAAAAGTGGCAAAATAGGTCCCCTTTGAGGTACAAACGTCCAAAATCTGTTGTTGGTGCAGCACCACTTTTAAAAATGTACACCCATGTTTCTTTTGTTTGTTTAGCTCTTTATTTATTAATTTAGAGTACATATTTGTGCTTATTAGCACTTAAAAGTACATATTAGTATCTTTTCAAATCACTCTGCATCACTCTGTACCTTTTTTCTGTGAGTAACTAGATTTCACAGCGTGTGTATATAAATTCTCTATTACATTTGGCTTGTATATTTATGCAATCTTGCCTCCTTTTTCACATCAATTCAGTTTTTTCTTCTCATTTCTGTTTTGTACAGTATTCTCTTTGCTGACGTGAAGGGCTTCACCAATCTTTCAACCACACTCTCCGCTCAGGAACTTGTTCGAATGCTCAACGAACTCTTTGCA[C/T]GATTCGACCGACTGGCACACGTAAGTAAACACACTTTTACCAGAATGCATATGAGTGTAAACTAAATCACAGTGTCTTTCGGGGCATGAAACGTATTAAAGCATTTTACTATGTTTGCCTGATATTGTGTTGTGTTGGCACGACATGCCTCTTTTGTGCCTTAAATCTGACGTTTAAATTTGTTTGTACTGGAGAGTAAAATGTAGTACAGTGGTAGTAGTAAGTCAATAATCATTTTATAGGAATGTTTGCAGTCACATTTATTTCAGAGTTGATATTAATAAGTGCTACAGATATTTTTGTAACACAAATTATGGCTAAAATGGAGTGAGCAAAAAATTGTTTGTTCAGATTGATGTAGTCAAACAGCTTTTTCTGTTATATTCTGTAGACTGAATTCAAATGATCTGAACGTCTCATAGACACTATTTAAGGGCTGTGTATAATAAATACTAATTGGATGTTAACATCTCTTTTTTATATGCTGGCCCTTACATCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39913
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087823 Nonsense 90 886 4 17
ENSDART00000134139 Nonsense 85 881 3 16
ENSDART00000137913 Nonsense 4 312 1 6
ENSDART00000140913 None None 246 None 6
Genomic Location (Zv9):
Chromosome 2 (position 42944904)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 42994368
GRCz11 2 42843786
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTGTTTATGGTTTGACATCTTTCTTCTTTTCCCCTCAGGAGCATCATTG[T/A]CTGAGGATCAAGATACTGGGGGATTGTTATTATTGTGTTTCTGGCCTTCC
Long Flanking Sequence:
GGTGGCTAAAAAATAACAACTTTTTGATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTTTTTTTTTTTTTTTTTTTTTTTTGTGGCAAGCAAAAAGCAAATTTCATTTAAAAAGAAATCCTGAGCGTTTAGCCCTGTATAAGTCTAAAATTTTATTTAAAATGGTCTTTAATGGGTCTTTAAAAGTCTTAAATTTGACTTGATGTAACCTGCAGAAACCCTGATTGATTATTTGTCTAGCATATACTTTTGTCCCTACTGACAGGGTTAAATGTTACAGTGTGCAATTTGTGCTTAAAGTGAAACTATTTTGAAGTTGTTGGACATTTACCACCTGATATTGAACCATCCCTTCATTGATCTAACTTTATGAATAAATAAAATGAGTTTTATTGGGATTGATTTGGTCATTCTGTTTATGGTTTGACATCTTTCTTCTTTTCCCCTCAGGAGCATCATTG[T/A]CTGAGGATCAAGATACTGGGGGATTGTTATTATTGTGTTTCTGGCCTTCCTGAGCCTCGGCCAGATCATGCTCACTGCTGCGTTGAGATGGGCCTCAGCATGATCAAAACCATCAGGTAATAGGAAAACAAATCATGCTAGATGTAGCTAGCTTAAATGCACAGATTTGTGCAATTTTACAGATACAAACCCACTTGAATAAAGCTAGGTTTTTTAAATGAGCATTATATTCCAACATGAATGTAAAATTACTTAGGTTACTGTCCAGGTTGCAGACAAATTGTATTGTTTAGAGCAGTGTTTCCCAACCCTGTTTCTGAAGGCACACCAACAAAACACATTTTCAACCTCTTCCTAATCAAACACCCCTAAATCAACTCATTAAAACATTAGAAGAGACTCCAAATTCTGAAGTTAATGGGTCAGATAAGGGAGACATCCAAAATTTTTGGTGTGCTTCAAGGAACAGGGTTGGAAAACATTGGTTTAGAAAGACACAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16359
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087823 Nonsense 101 886 4 17
ENSDART00000134139 Nonsense 96 881 3 16
ENSDART00000137913 Nonsense 15 312 1 6
ENSDART00000140913 None None 246 None 6
Genomic Location (Zv9):
Chromosome 2 (position 42944871)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 42994335
GRCz11 2 42843753
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCTCAGGAGCATCATTGTCTGAGGATCAAGATACTGGGGGATTGTTATTA[T/G]TGTGTTTCTGGCCTTCCTGAGCCTCGGCCAGATCATGCTCACTGCTGCGT
Long Flanking Sequence:
TATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTTTTTTTTTTTTTTTTTTTTTTTTGTGGCAAGCAAAAAGCAAATTTCATTTAAAAAGAAATCCTGAGCGTTTAGCCCTGTATAAGTCTAAAATTTTATTTAAAATGGTCTTTAATGGGTCTTTAAAAGTCTTAAATTTGACTTGATGTAACCTGCAGAAACCCTGATTGATTATTTGTCTAGCATATACTTTTGTCCCTACTGACAGGGTTAAATGTTACAGTGTGCAATTTGTGCTTAAAGTGAAACTATTTTGAAGTTGTTGGACATTTACCACCTGATATTGAACCATCCCTTCATTGATCTAACTTTATGAATAAATAAAATGAGTTTTATTGGGATTGATTTGGTCATTCTGTTTATGGTTTGACATCTTTCTTCTTTTCCCCTCAGGAGCATCATTGTCTGAGGATCAAGATACTGGGGGATTGTTATTA[T/G]TGTGTTTCTGGCCTTCCTGAGCCTCGGCCAGATCATGCTCACTGCTGCGTTGAGATGGGCCTCAGCATGATCAAAACCATCAGGTAATAGGAAAACAAATCATGCTAGATGTAGCTAGCTTAAATGCACAGATTTGTGCAATTTTACAGATACAAACCCACTTGAATAAAGCTAGGTTTTTTAAATGAGCATTATATTCCAACATGAATGTAAAATTACTTAGGTTACTGTCCAGGTTGCAGACAAATTGTATTGTTTAGAGCAGTGTTTCCCAACCCTGTTTCTGAAGGCACACCAACAAAACACATTTTCAACCTCTTCCTAATCAAACACCCCTAAATCAACTCATTAAAACATTAGAAGAGACTCCAAATTCTGAAGTTAATGGGTCAGATAAGGGAGACATCCAAAATTTTTGGTGTGCTTCAAGGAACAGGGTTGGAAAACATTGGTTTAGAAAGACACAAATGAGCAGGGCCAGACAGAATCAGAAGAAACTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39912
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087823 Essential Splice Site 182 886 5 17
ENSDART00000134139 Essential Splice Site 177 881 4 16
ENSDART00000137913 Essential Splice Site 96 312 2 6
ENSDART00000140913 None None 246 None 6
Genomic Location (Zv9):
Chromosome 2 (position 42941219)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 42990683
GRCz11 2 42840101
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTGGGATGTGGACATAGCCAACAAACTGGAGTCGGGGGGAATACCTGGG[T/A]AAGACACACTGATGCAATCTCTCATTCACACATTTTCCACCCTCATGAAC
Long Flanking Sequence:
TGACCCTTAATAGAGGCTAGATAGCAGAAGAGAGGCTCTTGTTGAGCAGGTGTGTGTGTGTGTGCTGCACTAACAGTCAGATATCACAGCACTCACACTACAGCTCAACACACACACAGAGCAGTGACAGTATGACCTCGATTCCACTTTTTATAAACAGCCATTTACTTCTGCCTGTTACTCAGGTCTGGGGTAATAGTATGATGCGTATATTTAAACTCCCTTTAAACCCAGTGTTTTTGTCCCAGTGTAAATCTACTTTGCAGTTGTTTAGTGACACCATTAGAGAACTGCAGCTAACCATCTGTCCTGACTCTTTTTCTGTTTGTTGTTTGTCCAGATACGTGCGCTCTCGTACAAAACATGACATAGACATGCGCATTGGCATCCACTCTGGCTCGGTTCTGTGCGGAGTTCTTGGTTTGCGGAAATGGCAGTTTGACGTGTGGTCTTGGGATGTGGACATAGCCAACAAACTGGAGTCGGGGGGAATACCTGGG[T/A]AAGACACACTGATGCAATCTCTCATTCACACATTTTCCACCCTCATGAACCAGGTGCTATTCAGAGCTAGTGCTATTGCTTGAATGGAGTTGGTATGACAGACGAGTCTTCTAAATAGCCCTTTGCTTTTCCACAGGCTGGAGACAAACATACTATCAACAATAGAGGACATTGTGTTGCTATTGAATTTCATCATAGATATATACGTTAGGCGTCGCCTATGCTATTGTTGTCTATTGGAATGAATGCATCAATAGAGCTGCCATTTTGATACAGGGTAGTGCTCCTTTGAAATGAATGTGGCAGTATATATATATATATATATATATATATATATATATATATATATATATATACACAGTACAAATATCTATGATTGGGAGTTTTCCCGGTGGTCAGTATGCAAATATTTTTTAAACTAGAAAAATTATAATTTTACATCACTTTTTTCTATTTTGATGGATAAGTGACCACACAGGCATTGCCGACAAATAGCATGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30826
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087823 Nonsense 441 886 10 17
ENSDART00000134139 Nonsense 436 881 9 16
ENSDART00000137913 Nonsense 289 312 6 6
ENSDART00000140913 Nonsense 191 246 5 6
Genomic Location (Zv9):
Chromosome 2 (position 42916415)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 42965879
GRCz11 2 42815297
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCAAACACTTGCCCTGTCTGTCTGTCTCTCTCTTGTATTGCAGCTTTG[G/A]TGTGATTTTGATAAATCGGGCTCATTCAGGAACCAGACGTTTAATGCATC
Long Flanking Sequence:
TGAGATGCACCTATATATTCAGAAGATTTACCTACTATAAGAAAAAAAAATGGTTAAATTAATATTGTGATTTTTATGAGAATTATAGAAATTATAGAATTTATAGAAATATATCAATCATAAAATATAGAATAAAAAGTAATATATTAATCATATATGTATACTTCTTTTTCAATTACTTCCTCCGTGTTTCCATTTTGGGTAATTTTGCTATCACTTTTGTTGTTGTTGGTAAAAGAATCTTGTTTTGATATTATTACAATGCCATGCAAAGATATTGCAGCATTTAAAACAGTCAAATGTGTCAAATGTTTTAATTATAAGTAATTTAATAAACTATTATAGTATTTTAATATCAGCCATTAATCTAATATCATGACCCCAACAGTCATAAAGTTAGTGCCCATGCAGTTCTATTACCCTTTATGCATATACACTGAATACATCTCTTCTCAAACACTTGCCCTGTCTGTCTGTCTCTCTCTTGTATTGCAGCTTTG[G/A]TGTGATTTTGATAAATCGGGCTCATTCAGGAACCAGACGTTTAATGCATCCGCCTCAATCCCAGATATCTGCTTCTACCCAGAGGTCTTTTCATCTGACGCCTCCAACACAAACACAAACACACACACATCCACAGCTTCTTCTTGCAAATCTCAGCCTGTTAAAAGGCCTGAGAGAATTCCAGCATTTGTGTAAACTGTTTGTAATCAATTGATTCAGTGCGAGTGGAGCGATGGGTGTTAATGGAGAGGTCGTCTGGCTGTTTGTTGACAGTATTTCGTGTTTACCGGAGTGCTGGCGATGGTGACCTGTGCGGTTTTTCTCCGACTGAATTCAGTTTTGAAGTTGGCGATCCTTCTCATCATGATTGCCATCTATGCTGTCCTGACCGAGGCCTTTTACACGCCGTTGTTCATTCGATACGACACGCTGACTCTCAATCAGAGGTATGTACACTGATTAAGTTGACAAATTTAAGTTGTTTGAACATAAAACAGTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39911
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087823 Nonsense 572 886 13 17
ENSDART00000134139 Nonsense 567 881 12 16
ENSDART00000137913 None None 312 None 6
ENSDART00000140913 None None 246 None 6
Genomic Location (Zv9):
Chromosome 2 (position 42887786)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 42937250
GRCz11 2 42786668
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGAATATACGGCTCGTCTGGACTTCCTATGGCGTGTGCAGGCGAAGGAA[G/T]AGATAAATGAGATGCGAGAGCTGCGTGAGCACAATGAGAACATGCTCCGG
Long Flanking Sequence:
TTACAGTGTAAAGGATTTAAAGGATGAGACACTGAAGACTGGAGATATGAGGCTGGAAATGCAACACAGGACTAAACAGCATTTAAAAAACAGAAAACAGTTACTTTAAATTGTAAAAATCTCACAAAATGTCACCATTTATGTTGTATTTTAGCTATATTTAAATAAAGGCATTCTTCTCTTACTTTCTTTTCTTTTTCTCTCTGTCTGTTCCGAGTTTAGTAGCTAGACAAATTCATAACATCCTGTGCATTAATATTGACAAATATTTTGCGATGATAAGTGTGTATTGATGTTTTCCCTGACCTGTCAAGGACTTTGAGGCATGGGCCTGTAACTCTGATTGACCGTCCAGTCCTGTGTTTGTGCTTGTTTATGCTGATTGAATGTATCTTGTGGTGCTTTTTTCTCTCTGTTGTCTGACCGGCTTTATTCTCTCTGTCTCTCAGCTGGAATATACGGCTCGTCTGGACTTCCTATGGCGTGTGCAGGCGAAGGAA[G/T]AGATAAATGAGATGCGAGAGCTGCGTGAGCACAATGAGAACATGCTCCGGAACATTCTTCCCAGCCACGTCGCTCGCCATTTCCTGGAGAAAGACAGAGACAATGAGGTAGAGAGACAGATTCACTCCTTCAGTCTGACAGGGAAAACATGGCAGCACTTAGACAGCAAGAACATGCGAGGAGACGATGAATCACTGCCACTTTCACTCTCTGGCCTCTTAATTAGCATGACAGTCAACTCTCTTTAAAACAGCTTTAGCTGCGCAAGTCAAAACCAATTAAAATACATGCATAAATCACTAATGACTATACAGTACGTGACAAAAGTAAATCAGTCAAATTTGGTAAGGTCAGTGCACTCTGTAAGAAATGGTGTATATTTTAGTTCAATGAAAGTTGAAAATGATAAACTGAAATGCTTCCAATAATCATTTATTTGTTTTGCTTTGAAAAATAACAAATAGCAATTAGCATACTTGTCAGCCTTCCCGTTTTTCCCG
Associated Phenotype:
Not determined