Busch Lab

ZMP

si:dkey-119f1.1

Ensembl ID:
ENSDARG00000058719
ZFIN ID:
ZDB-GENE-070705-287
Description:
structural maintenance of chromosomes protein 6 [Source:RefSeq peptide;Acc:NP_001121806]
Human Orthologue:
SMC6
Human Description:
structural maintenance of chromosomes 6 [Source:HGNC Symbol;Acc:20466]
Mouse Orthologue:
Smc6
Mouse Description:
structural maintenance of chromosomes 6 Gene [Source:MGI Symbol;Acc:MGI:1914491]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa6006 Nonsense Mutation detected in F1 DNA Not yet available
sa19667 Essential Splice Site Available for shipment Available now
sa38310 Nonsense Mutation detected in F1 DNA Not yet available
sa39764 Nonsense Mutation detected in F1 DNA Not yet available
sa39763 Nonsense Mutation detected in F1 DNA Not yet available
sa14490 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa6006
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081633 Nonsense 65 1090 2 26
Genomic Location (Zv9):
Chromosome 2 (position 6015211)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 6460939
GRCz11 2 6372821
KASP Assay ID:
554-3916.1 (used for ordering genotyping assays)
KASP Sequence:
GGTGGGCATTATCGAGAGCATCTCTCTGAGAAACTTCATGTGCCATTCGT[T/A]GCTCGGGCCCTTTGCGTTTGGTCCAAACGTCAACTTTGTCGTAGGAAATA
Long Flanking Sequence:
GGCATCCAGAGACTCGCGAAACTTCCCACCCTACTCATAATTCTCTCTTCATATAGCCGTATGCCTATTACATATCCATAAAACACTGTGATATAACCGCGCTCGGATCGGATCACTTTCTCACTGCAATCGAACCGCTCCAGGGTTCGTTTCAATCGAGCCGAGACCACCTCATTCAAGCGATCTCGGAGCGATTACTTTGGCGCGGAACAGAGCGCGATTGCCCTGTTCACATATGCCAATCGAACCGCGCTAACTGGGCAAACGAGATACGTTCCGAAACAAAAGTGTAGGTGTGAAAGCACCCTAAGACATACTTGACACAGAACAAATGTCTTGCCAGCTAAGTTTGTTGTGTTGTAAAAAAATCAGAGATATTTTTTGTTGTTTTCAAATGATTTTTTCACATCTTTGTGTGTGTGTGTGTTTGTGTTTTCAGGTGACTGGTGAGGTGGGCATTATCGAGAGCATCTCTCTGAGAAACTTCATGTGCCATTCGT[T/A]GCTCGGGCCCTTTGCGTTTGGTCCAAACGTCAACTTTGTCGTAGGAAATAATGGAAGTAAGTACGGGACCTAAAATTTGCCACAGTACAGTTGAAGTCAGAATTATTAGCCCCCCTGTTTATTTTCCCCCCAATTTCTGTTTAACGGAAAGAATATATTTTTTTCAACACATTTTTTCAACAATAGTTTTAATAACTCATTTCTGATAACTGATTTATTTAATCTTTGCTATGATGACGGTGCATAATATTTTACTAGATATTTTTCAAGACACTAGAATTCAGCTTAAAGTGACATTCAAAGGCTTAATGCAGTGGTTCTCAAAGGTTTTTCATCAAGTACCATCTCAGAAAAAAGTTGTCATTGCAAGTACCACCATAATGAGTAGTAAATAGTGAAATACAGTAGCGTATTAGGTCCAGTAAAGCAGCTAAAAGCGTATGCATATTAGTTCCTATTATTAAGAACATTTAAATTAAAATGTGCTTTTAAAAATTAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19667
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081633 Essential Splice Site 165 1090 4 26
Genomic Location (Zv9):
Chromosome 2 (position 6010893)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 6456621
GRCz11 2 6368503
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGAATTTCCAGTGAGGGAATCCGAACGTACAAACTTAAAAGCCACACCGG[T/C]ATGCCTACAATTACACTAACGGTTTATTTTTGGGTAGCTTTAAGGGATAG
Long Flanking Sequence:
TTGTTGTTCCTAAAACTTGGATAGGCGACAAGACTTTAGTCAGGTAGTGATATGAAAACAAGCTATTATGTGTTTTGTAGAAGCTGGCATGCATGACCACAAATTATTTCTTTTGAATTTTGTGTATAATTGTTTGGTGTGTATTTGTGTGTTAGGTGGGAAAAGTGCCGTGCTGACAGCTCTGATTGTAGCCCTGGGCGGTAAAGCTCTCACCACCAACCGAGGCTCCTCTCTCAAAGGATTTGTTAAGGAAGGAGAGAGGTACAAACACACCCATCCTGTTTTTCCCTGCATGTAACCACAGTCTGTATTTAGTCTCTCACACTGTTTAATTTGTGTGTGTGTGTGTGTTTAATAATCAGCTCTGCAGATGTGTCCATCACGCTGAGAAACAGGGGTCGTGATGCGTACAAACCGGAAAAGTTTGGCCAGTCCATTGTGGTTGATCTTCGAATTTCCAGTGAGGGAATCCGAACGTACAAACTTAAAAGCCACACCGG[T/C]ATGCCTACAATTACACTAACGGTTTATTTTTGGGTAGCTTTAAGGGATAGTTCACCCAAATAGCAACATTTTCTCTATTTTTACTCGCCCTCTTGGGGTTTCAAACCTTTATGAGTTTCCTTTTTCTGTTGAACCCAAAGGAGATTTTTTTAAGAAAGCTAGAAACCTGTAACTAGGGGGCTAATAATTCAGGAGTGCTAATAATTCTGACTTCACTTCTATATTCATGTGTATACAATAATAATAATAATAGTAATAATTCCTTACATTTATATAGTGCTTTTCTGGGCACTCAAAGTGCTTTACATAAAGGGGGTAATCTCCTCATCCACCACCAGTGTGCAGCATCCACCTGGATGATGCGACGGCAGCCATTTTGCGCCAGACCGTACACCACACACCAGCTGATTGGTGGAGAGGAGACAGAGTGATGAAGCCAATTATGATATGGGGAGGGTTAGGAGGCCAGTGGGCAGATTTGGCCAGGATGCCAGGGTTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38310
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081633 Nonsense 480 1090 13 26
Genomic Location (Zv9):
Chromosome 2 (position 5988672)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 6434400
GRCz11 2 6346282
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCGACTCTAAACAGCGTGACCTGGCCGCCATGGAAAGTAGTCGAAATAAC[C/T]AGCTTCGTCGTTTTGGCGAGCACATACCAGCACTGATGGAGGCTATAGAT
Long Flanking Sequence:
CAGAAGTGTTGTTCAGCCACTAAAATCTTCCGATAAAAGATTGATCAGACTATTTTGAGTTTCATAAGGGACCTTTTACAGCATCTATAATGTAGATTTTAAATTAGTTTAACAACAAAACCCCAGTAAATAATGCTATTCCGCCTTGTCTCTCCCTATATTGTTTACCATCCAACTCTAAATATTCACTCTGAAATAGCATGTCAGTTTGGCTTGCTCGCTGCCGGACAAGCAGTAGTCGCTTTTAACACATGAGAGAGGGTTCTTTTGCTGTGCTCGTATTTAAGATGCGTGGCTCTAGACGGCAGGGGAGGGACTGTGATTTAGAGATTTATGCTAAGCTGTTAGCATTGTAGAAGATCACCTACTGCACCTTTAAATTTTGTTTTCTATTTCTTTTTTTTCCCCCATAATTCTGTAGCCGTGAAAGGCAGGACCTACAGCGTGCGATCGACTCTAAACAGCGTGACCTGGCCGCCATGGAAAGTAGTCGAAATAAC[C/T]AGCTTCGTCGTTTTGGCGAGCACATACCAGCACTGATGGAGGCTATAGATGAGGCTCACCATCGAGGGAAGTTCAGGATGAAACCTGTCGGGCCGCTTGGTAATATCCTGAAGGTTTCATTTACACAAGCTACCCCAGATTGTTTATTTCAGGATGGATTGAGCACAAAGTAAATATATATTAACATTTTCTTGCAAAAAGGAATTCAGTGCAACATTTTATACAACAAATCTGACTCAGTTACACCAATTCTGTCAGAAGGAATGGGACAAAATTCCTTCAAACTGTTGTGAGAAGCTTGTGGAAGGATACCCAAAACATTTGACCAAAGTTATACGGTTTAAAAGTAAAGCTAAAAAAAACCAAGGAAATGTGTGTTAACTTTTGACTGTAGAAATTAATAAACAAATCTAATAAAAAATTATCTCATTATTCTGGCATTTAGCAAATGTAAATCGTTTAGGTAATCCTAACGGACCTGAAATAGTAAACATCTAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39764
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081633 Nonsense 681 1090 17 26
Genomic Location (Zv9):
Chromosome 2 (position 5981769)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 6427497
GRCz11 2 6339379
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTAAACTAATGTGTGTCTTCTTTTTTCCAGACATTTGCAGTCTGCTCTA[C/T]AGACCCAGAGAGCACAGTTGGATCGCTTTCAGCAGGACATGCAGCAGGTC
Long Flanking Sequence:
GGCCTTTACATATTTTCACTCATTCATTCATTTTCGGCTTAGTCCCTTTATTAATCAGGGGTCACTACAGCGGAATGAATCATCAACTTATCCAGCATATGTTTTTCGCAGCAGATGTCCTTCCTGGTGCAACCTATCACTGGGAAACACCCATACACTCTCATTCACACACATACACTACGGACAGTTTAGCTTATTCAATTTACCTGTACCACATGTCTTTGGACTTGTGAGGGAGCGACCTGAAGGAAACCCACACTAACACTCGCTTTGGATAAAAGCGTCTGCTAAATGACTAAATGTAAATGTAAACACAGGGAGAACATGCAAACCCCACACAGAAACGCCAACTGATCCAGCCGGGGCTCATATCAGCGACCTTCTTGCTGTGAGACGACAATGCTACCTACCGCCCCGCCCGAAGCCAGTTGTTAACAGCACGAATTGTGACCTAAACTAATGTGTGTCTTCTTTTTTCCAGACATTTGCAGTCTGCTCTA[C/T]AGACCCAGAGAGCACAGTTGGATCGCTTTCAGCAGGACATGCAGCAGGTCGGTGAGGAAGAGAGGCAGAACCAAACTCTTCTTCGCAGAGCTTACGACGACCGCAAGAAAGTCCAGGTTACTAAAATACCAGCAGCGCACATCACTACATTATCGAGATTTAACTAAATGTGCCCTAAGATTTATTTATTTCATTTTTTTTTTTTTTTTTTTTGCTAACAGGAACGTTCCCGGAAACTTCAGGCAGAGTTGACGGAATTGCAGAACGTGGAGGAACCTCAATCAGAAGACCTAAAACCTCTGGTAACAAACAAATTTCCTTCAAGAAGATTAATATGCCTTTGTATTTGTGTAATTTACCCGTCTCATTTTGTGTGGGTGTTCAGGAGGAGGAACTGGAGGAGCTGAGCGGACGCATAAGTGTTTGTGGAGAGGAGTTCGAAGCTCTGCGGAGACAGACACAAACCTGCAAGAAGGAATATGAGGAGGCTGAGAAAGTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39763
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081633 Nonsense 823 1090 20 26
Genomic Location (Zv9):
Chromosome 2 (position 5976934)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 6422662
GRCz11 2 6334544
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACAACAGTGATCAGGAGGTGGAGAGGAGTAAACACCACAGAAAACACTA[T/A]GAGGAAAAACGAAAAACCCACTTGCAAATGATCGAGACACTAAAGACGAG
Long Flanking Sequence:
CAGTGCTTTTAAATTTTCTCCGTAAATAAAACTTGTATCAGAGTTGCAGCAATGTTTTGTTGCCTTGTCAATTACTATGAAAATGATTGATGGTTTTAATCTGGTTTCATCTGTCATCATTATAATTTAAAGTGAAGCCAAAATTTGCATGATGCATACCACCCCAACCCATTATTAATGTGTTCAACATATTAAAAGAAAGTTTGAAAAATGAAGCAACGTCACAGTCTGTGCGATTAGCTATTATAGGACGCTGTTGCAAGCACCTAATTTTTCAACTATCAAATAACAGAGTAAAACAATAATTGTCATGAAAATTTTTACATGTAATTCTGTTTTTTTTTTTATGTTTGGCACGTGTTTGGGCGATCAGTATGTTTTGGCTTACCCTTTTTTGGATGTAAACCGTAAACAATTTTGTTTTTACGTGATTGTATGTAGGAGCGTTTGAACAACAGTGATCAGGAGGTGGAGAGGAGTAAACACCACAGAAAACACTA[T/A]GAGGAAAAACGAAAAACCCACTTGCAAATGATCGAGACACTAAAGACGAGCCTGAATCAGAAGGAGCAGGAATTACAGGTAAAAAAAAATATGTTTTAAATAGTTTTAAATATGAAAAGAATAGTGTGTTTTTTATTATTATTATTTTTATTTTTATTTTATTTTTTTACAGGCTGCAATTGCAAAGGCCTCAGAAATCTGCCCAGAGCGCTCGGATGTGAGGAGAACGGCGAAGAGTTTGGACAGCGAGATCAACCGACTGAAAAGCAAGATCAATACACAGCAGGACCAACAGGGACACAGAGACACCATCGTCAGGTACATTTACAAGCTTCACGAAGTATTTCAAAAGAATGTGAGCTGATGGTGTTTCACCCAAAAGTCTAATTAAAGAAACTAGTAATTGTGTGTAATATCTAGAAAAAAAGTTCCAGGATTATTAAAGCTAATAAAAAATAAGTTTGCAGTCAATTTACTCATCCTGCAGCTCTGTCCATCCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14490
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081633 Nonsense 1019 1090 24 26
Genomic Location (Zv9):
Chromosome 2 (position 5968554)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 6414282
GRCz11 2 6326164
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGCTTCGTCCTGTCACTGTGGGAAATTGCTGAAGTTCCTTTCCGTGCCT[T/A]GGATGAGTTTGAKGTCTATATGGTACAAAAAAACAAAAATAACCTGGTTA
Long Flanking Sequence:
GTGTGCGCCATCACATGCAAGGTTTTTGTATTTATAACCACCTCAGAGGATATTGGGGGTCATTTTGGGGGTCGCAGGCAGAAAAGCTTGGGAACCCCTGCTTTAAATAAAGTTTATTCAGCAATAATTCTCCAGAACTGATAGCAGATCCTTAAAATGGCTTGAGCCCTTAAAATCATCCCAAATTCTCAAATTTGAAACTTAAATATATTTTGAGAAAATGAAGGGTGAGTAAATGATGACAGATTTTAAATTTTTGGGTGAATTTACAATCATATTTTATAATTATAAATTGTGGTCTTTTTGCACCCTTGACACAATGCTTTTTTTTTTTTTTCGTGATGATGATTATGTGTTTTTTTCCCTTCAGGTTCAGCCAGGAGAGGGTGGGAAGGCTGATCTGAGTGACATGCGTTCGCTATCTGGAGGAGAGCGTTCGTTTTCCACCGTGTGCTTCGTCCTGTCACTGTGGGAAATTGCTGAAGTTCCTTTCCGTGCCT[T/A]GGATGAGTTTGATGTCTATATGGTACAAAAAAACAAAAATAACCTGGTTAGACTGTATCTCGCACAGCAAGTGTGTATTGTGTGAAGACTTGTATTCTTTAGAACAGTGGTTCTCAATTCCAGACCCCCCATCCTGCACATTTTGTATGTCTCACTTACTCGACACACAAGGATCAGTTCAGGAATCTCTCCTTTAACGAGCTGATGATCTGAATCAGGTGTGTTAAAGAGCCATGACACCCCCCACTTTCAGTTCAGGTTCACCTTAGATTTTTTTCAAAAGATGCATCATTATGGGCGTGGAGCTCCGAGCAAAGGGCAGGGGTGGGCGTGGCCAGTGGAGGAGGCGAGGAGGGGAGCGAACAACTGGTTGTCAGTCGGCTCACAAAATTGATGACCCATGATTTAATAGTTTACAAAGTTAAAATGCAAAGAAATAAACAGTAATTTAAATGCTACATTTGTTATTCGTAATTTGATATACAGATAACCACAATTTA
Associated Phenotype:
Not determined