ZMP
si:ch73-190m4.3
Ensembl ID:
ZFIN ID:
Description:
probable E3 ubiquitin-protein ligase HERC3 [Source:RefSeq peptide;Acc:NP_001139096]
Human Orthologue:
HERC3
Human Description:
hect domain and RLD 3 [Source:HGNC Symbol;Acc:4876]
Mouse Orthologue:
Herc3
Mouse Description:
hect domain and RLD 3 Gene [Source:MGI Symbol;Acc:MGI:1921248]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa8570 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa39689 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa8570
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000112994 | Essential Splice Site | 421 | 1046 | 9 | 24 |
| ENSDART00000141977 | Essential Splice Site | 421 | 1046 | 10 | 25 |
Genomic Location (Zv9):
Chromosome 1 (position 51167481)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 50016572 |
| GRCz11 | 1 | 50660398 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GACAGCTGGAGGATGAAGCTTCATGACAACWGCGATTCCAGCATCACTAA[G/T]TGAGTGTGTGACATCATCCCCATYGATCATAATAATGGCCTCACTAAGGA
Long Flanking Sequence:
TCGACTGTGGAGGTAACTCATAATCCATATAAACACACATGTTCATTTTCTTATGAGAATCAGCAAGTGGCTTCTATTAGGCCAGTATCTGCTTTTATCCACATGGTGGCGCCGATGCATCATTAAAAAGGGTTTACAGTCCATGACCATACGAACACACATCTTCCCGGCAGCAAGAGTGTGATGTGTTTTATTTTACTGCTACGTTTTGATTTATGTGTACATCAATTATTGCCAGTTTTAATTAGGACACTTCTGATCATAATTGTGAAAATGATTGTATATCTGATTGTGTGGTTTTATAAAATCTGATTGTTTATAGTGTGTAAATATAGAGTGTATATATGTAATATCCGATTGTGTGTTTATGAACAGGGTTTGTCTTGTCCTGATGATTTCCGCATTCTGAACACCACCAAAAGCATCGCTCTGATTAATTCTGAGAGTCTGGACAGCTGGAGGATGAAGCTTCATGACAACAGCGATTCCAGCATCACTAA[G/T]TGAGTGTGTGACATCATCCCCATTGATCATAATAATGGCCTCACTAAGGAAATAGTTTCATGACTTCATAGACTACACTGTAAACATATCTGTGTATTCACTGTTTCCCTATTTTGTGATTCACGAATGTTTTCAGTTTGTTTACGCTTGTGAATTGCATTATGGGATGTTGATCTCTGCTCTGGCGACTTTTGATGTTGAAAATTTAACTCTGCAGTTTAACAAAGTAAAATAATATAACATGAATATAATACAAAATAACAATAATACAATGTATAATAAATAATAAATAGAGAAATTAGTTTGTAAAATAACAGAAAATGTGCTGGCAGTTTATTATAAGGTTTTTGTAGCGTAATACACAACCCCAACCCAGGAATTATATCACTTTAAAGGATAGAAAGTTTTCATAAAAGTCACTTTTTTCAAACTTTTTAAAGTTAAAAGTTGTTGGATTAAAGATCAAAATCCCATAATGCAACTCAAAAGCATAAATGTCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa39689
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000112994 | Nonsense | 842 | 1046 | 20 | 24 |
| ENSDART00000141977 | Nonsense | 842 | 1046 | 21 | 25 |
Genomic Location (Zv9):
Chromosome 1 (position 51189980)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 50039071 |
| GRCz11 | 1 | 50682897 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTGTTTTTGTCTGTGTTTTGCCAGGAGTTTGCAGCAGCTGCTGGAGTTT[G/T]AGGGTGATGTGGAGGAAACCTTCTGTCTCAACTTTGCCGTAAGTTCATGG
Long Flanking Sequence:
TTGTTTGTTTAAATGCTTCTTCAAACTATCTTCTTTTGTCTTTAACACAACAAAGAAACTCATCAATGTTTGGAACCACTTTAGCATGAGCAAATTTTCATTTTAGGATGAACTATCCCTTTAATGTTGCAATAACCATGTCCTGGTTCTTGTTTTGAGACCTCATTTGGCCTCATTTCTGACTCTCCGCTTATATAAATGCCATATTTTATATACATTTAATAAAGTCATGGGCAGAAAAGTGCCATTTGTTAAAAGTGGGAGATGATGTGCAGCCCCTGGCTTTCCTGCATAAGCCAGGGGTTTGTGTTTTTATCCTGCAGCTGCTGAGCTCTTAACTGCGATTACACCAGAGAAGGACAATTAAATGCCTGTTGATGACTTTACAGATTAAAACAGAGAACATTTTCCAAAACTGCAGGTCGGATGTTTCCTAAACGTTCGTCATGTGCTGTTTTTGTCTGTGTTTTGCCAGGAGTTTGCAGCAGCTGCTGGAGTTT[G/T]AGGGTGATGTGGAGGAAACCTTCTGTCTCAACTTTGCCGTAAGTTCATGGACACCAAAATATGACTCCTTTATTTAGGCCACATCAGGTCACAAGAGGATTTATCTGATTAGAGGAACGTCACTTATAGCTGTAGTTTAAAGTATAGAGCCGTTGACAGGTCAGTATTTTTAATTAAACAAATTGAACTAAACCTGTTTTTGATATCTCACACACACACACACACACACACGCACACACGCATATGCTGTCCTGATGATGTCCTGAAAACCCTTACAAAAACCCTTGTGATAAAATGACATTAAGCAGATGTTTTTTGTGGTTTATTATGAAGAGTAATACAATAATGCAACGTTATATTGTTCTTTGACAGTGTTAAGTGAAATTGCTAGTGAAAAATTGTATTATCATTTTGTAATAAAAATTAATTTAGACTTTAGTGCAATTTACTTATGGGACGGTTCATATGTGCTTGTATTATAATAATCATTGTACATCGAA
Associated Phenotype:
Not determined