si:ch211-235f1.1

Ensembl ID:

ENSDARG00000074381

ZFIN IDs:

ZDB-GENE-050522-234, ZDB-GENE-070424-163

Description:

Novel protein similar to vertebrate FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocy

Human Orthologue:

FARP1

Human Description:

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) [Source:HGNC Symbol;Acc:

Mouse Orthologue:

Farp1

Mouse Description:

FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) Gene [Source:MGI Symbol;

Allele Name	Consequence	Status	Availability
sa38239	Nonsense	Mutation detected in F1 DNA	Not yet available
sa39532	Nonsense	Mutation detected in F1 DNA	Not yet available
sa25509	Nonsense	Mutation detected in F1 DNA	Not yet available
sa9536	Essential Splice Site	Available for shipment	Available now

Allele Name:

sa38239

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108619	None	None	1033	None	26
ENSDART00000108919	Nonsense	100	141	3	3
ENSDART00000142944	None	None	1025	None	27
ENSDART00000143361	None	None	811	None	13

The following transcripts of ENSDARG00000074381 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 1 (position 2151427)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	2246847
GRCz11	1	2394641

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTTGGAGTTTCAGGATCAGCGGAAAATGATTGTGAGCAACGCTTGTCTTT[T/A]ATTTCAATATGTGAAACATGAGCTACCTCTATACACACAGTACTCAGGTG

Long Flanking Sequence:

TTTTATTTTTTTCAAAAAGGTTGTGGTGTGTGTGTTATGAGTGTAAAGTCAGCTGGTCTGCAGGTGTGTGTGTGTGTAGCCTGAGGTCAGAGGTCATCCATGTGAAGCGAATTCTTCATACTGTTGTGAAATGGATGGACAATCAGCAGAGAGTTTGGATCGGCTTGAATGACAGACTCTTGTGTTTACTGTAATTACAGATTTAGTGGAGTCTTTCATTCTCCCCGCAGTGTAAACAATCTGGATGCCGTTTTGTTTGCAGTCTATTTTACGGGTGAAACAGGATACTTAAGACTTTTCTCTCAGTTTCACAGGTGTTTGCATTGTATCATCTGCTTCATGTGTAACGTGTGATGTTTTTTTTGTGTTTTGACAGCAACGGGCCCCAGGGAAGGCGCTGTTTGACCTGGTTTGTTCTCATCTCAACCTCGTCGAGGGCGATTACTTCGGTTTGGAGTTTCAGGATCAGCGGAAAATGATTGTGAGCAACGCTTGTCTTT[T/A]ATTTCAATATGTGAAACATGAGCTACCTCTATACACACAGTACTCAGGTGTCATGTTCTGTGACCCAATTAGGAATGTAAACACAGTGGCTCCGTCCCAAACCCTAGAGAGATGCCTATATCGATAACAGCCATATTTATTTATTTATTTTTTTACAGTGTTATTTTATTTATTTTTTTTATTTGCTTTTTAATTTACCATGGCATTAGGTGTTTAGGCTTTCTTCTTCTTATGAATACTTTTTGGGTAAATAATGATTACCAGCTTTTGCAAAATGTTATGGTTTGATTCTCTTCTCAGGTGTGGCTGGATCTGCTGAAGCCAATTCTCAAGCAGATTAGACGTGAGTATACATGTCTGAGTGTTGTTCTGACTGTTGTTCTGACTGTTGTTCTGACTGTTGACCCGAATGTTGTTCTGACTGTTGTTCTGACTGTTGACGCGAATGTTGTTCTGACTGTTGACGCGAATGTTGTTCTGACTGTTGACCTGAATGTTGT

Associated Phenotype:

Not determined

Allele Name:

sa39532

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108619	Nonsense	104	1033	3	26
ENSDART00000108919	None	None	141	3	3
ENSDART00000142944	Nonsense	104	1025	4	27
ENSDART00000143361	Nonsense	104	811	4	13

The following transcripts of ENSDARG00000074381 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 1 (position 2151758)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	2247178
GRCz11	1	2394972

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGGTTTGATTCTCTTCTCAGGTGTGGCTGGATCTGCTGAAGCCAATTCTC[A/T]AGCAGATTAGACGTGAGTATACATGTCTGAGTGTTGTTCTGACTGTTGTT

Long Flanking Sequence:

TCTGCTTCATGTGTAACGTGTGATGTTTTTTTTGTGTTTTGACAGCAACGGGCCCCAGGGAAGGCGCTGTTTGACCTGGTTTGTTCTCATCTCAACCTCGTCGAGGGCGATTACTTCGGTTTGGAGTTTCAGGATCAGCGGAAAATGATTGTGAGCAACGCTTGTCTTTTATTTCAATATGTGAAACATGAGCTACCTCTATACACACAGTACTCAGGTGTCATGTTCTGTGACCCAATTAGGAATGTAAACACAGTGGCTCCGTCCCAAACCCTAGAGAGATGCCTATATCGATAACAGCCATATTTATTTATTTATTTTTTTACAGTGTTATTTTATTTATTTTTTTTATTTGCTTTTTAATTTACCATGGCATTAGGTGTTTAGGCTTTCTTCTTCTTATGAATACTTTTTGGGTAAATAATGATTACCAGCTTTTGCAAAATGTTATGGTTTGATTCTCTTCTCAGGTGTGGCTGGATCTGCTGAAGCCAATTCTC[A/T]AGCAGATTAGACGTGAGTATACATGTCTGAGTGTTGTTCTGACTGTTGTTCTGACTGTTGTTCTGACTGTTGACCCGAATGTTGTTCTGACTGTTGTTCTGACTGTTGACGCGAATGTTGTTCTGACTGTTGACGCGAATGTTGTTCTGACTGTTGACCTGAATGTTGTTCTGACTGTTGACTTAACTGTTGATCTGACTGTTGACCTTCATGTTGTTCTGACTGTTGATCTGGTTGTTGTTCTGATTGTTGACCTTCATGTTGTTCTGACTGTTGATCTGGCTGTTGACTTAACTGTTGTTCTGACTGTTGACCTGCATGTTGTTCTGACTGTTGATCTGACTGTTGTTCTGGCTGTTGTTCTGACTGTTGACCTGCATGTTGTTCTGACTGTTGTTCTGAATGTAGATCTGGCTGTTGTTCTGGCTGTTGTTCTGACTGTTGACCTGCATGTTGTTCTGACTGTTGTTCTGAATGTAGATCTGGCTGTTGATCTGGCT

Associated Phenotype:

Not determined

Allele Name:

sa25509

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108619	Nonsense	506	1033	13	26
ENSDART00000108919	None	None	141	None	3
ENSDART00000142944	Nonsense	502	1025	14	27
ENSDART00000143361	None	None	811	None	13

The following transcripts of ENSDARG00000074381 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 1 (position 2177207)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	2272627
GRCz11	1	2420421

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CAGAGTCCTGACGGACGGCAGCCCTCTCCTCTCACCAGCCCGCTACTATA[C/A]GACGCCGGATTCATCCGCGCAGACGACGAGGACGAGGTTCGGAGGAAGGT

Long Flanking Sequence:

GTCTTCAATCTGTTTTAAATGCAATCGTGAAATAACCATCGTGAGTTCAGTGAATCGTTACATCCCTAATCGTAGCCTTGCAAGTACATAATTCTTGCCCTTTACCAGTTCAGCTTTTTTGCAGGCTAGTTTTACTAAGCTGAGTCCTAATTCTAGCATTTAAAATCAATTAACGTGTCTGATTGTGCTCCTGGAGGGTTATTATCTTACAAAGTTTATCCATAACTCATTTAAACACACCTGAAGCAGCCGATCAGTAAACTCCTGTGAATGTATGGAGCCCAATCACACACACACCTCTGATTTAAGTGTCTTTAAATGATCATCAAGGCTTCAGCATGACCTGCCTGTTCTCCTTTAGGTCCAGTGAGCCGCAGTCCTCAGCACAGCGAGTCTCCGTCTGCAGGACAGATGATGGTGAACGGCCAGAAGCAGAGTCTGAGCGTAGGCCAGAGTCCTGACGGACGGCAGCCCTCTCCTCTCACCAGCCCGCTACTATA[C/A]GACGCCGGATTCATCCGCGCAGACGACGAGGACGAGGTTCGGAGGAAGGTTTGTCTTTTGGGGAATGAGGATGGAGGGAATCGTACATCTTTATAATGTAGATTTGTATAACTAGCACTTCTTGTGTGTGTTGTAAACCGCTTCAGACAAAAGGGTCTGCTTAATTCCTTCGGCTTAGTCCCTTTATTCATCAGCGGTTGCCACAACGGAATGAACCACCAACTTACCCAGCATATGTTTTACATAGCGGATGCCCTTCCAGCAGTAACCTAGTACTGGGAAACCCATACACACTCATTCAACCACACACTCATACACTACGGCCAAATTAGTTTATTCAATTCACTCTGCCAGTTAGTTTCTCTCTTGAGCACCTCATGCATTTGTTTTTGTTGTGCTGTTTCCGTCTCCTCAGCGGTGCATTTCAAGCACCCTTGTCTAATTCCCCCACTTTAAAGGGCCATGAAACCCCCTCGTTTCACCAGGGTGTTTTCACACCT

Associated Phenotype:

Not determined

Allele Name:

sa9536

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108619	Essential Splice Site	771	1033	20	26
ENSDART00000108919	None	None	141	None	3
ENSDART00000142944	Essential Splice Site	763	1025	21	27
ENSDART00000143361	None	None	811	None	13

The following transcripts of ENSDARG00000074381 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 1 (position 2188925)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	2284345
GRCz11	1	2432139

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GATYACTTGACCTTGTCAATCTGTATGTTCACTTGATGTGTTTGTGTGCA[G/A]TTCAGTGATGTTGTGATGTACACGAGTCGAGGATTGACGGCGTCCAATCA

Long Flanking Sequence:

TATGATGTATGTGATATTTGTGTGTGTGTGTGTGTGTGTGTAGCTGCGCTGGCGGACGTCTCAGAGCTGGTTCTTCAGCTTCACACCACACTCATGAAGATGGAGAATTTCCAGAAGCTTCTGGAGCTCAAGAAAGACCTGGTGGGCATCGACAGCCTGGCGGCTCCTGGACGGGTCAGTCAGTTCTGCAGTTATGATCAGTGATATTACAGTAATGATGCTTATAAACTGCTCATGAGCTCTCGCTGTTTGCTCTGCAGGAGTTCATCAGGCTCGGCTGTCTCAGCAAACTCTCTGGGAAAGGCCTCCAGCAGAGGATGTTCTTCCTGGTGAGACCGTTAACATGTTTTGGGAAACAGTAATACCATGGTATTTTACCGAATATGCCTCTTTAAGTGAATCGCTTTTCTCCATGGTTTCAAGAGATCGAAAATAATGTAAATAAGGTATGATTACTTGACCTTGTCAATCTGTATGTTCACTTGATGTGTTTGTGTGCA[G/A]TTCAGTGATGTTGTGATGTACACGAGTCGAGGATTGACGGCGTCCAATCAGTTTAAAGTTCACGGTCAGCTTCCTCTCTACGGCATGACGGTGGGTCAGACTTCACCTATTTTACCCCACAACATAAACACTGATGATCTTTCAGCTTCGCACAGCCAAACCAAAACATTATACCCTTGATATATGTTTAGCTTTAGGTGAGGAGAGCAAAATTAAGTGACAATTTAAACCCAAATCTATTAGAAAGCAGGTTATGTTCTGCTCACACGTGGGCTGATGGCCTTCATTTCGACATCTCTCTTCAAGATGTAGCTTAAGCACACAGACAGCTGCTTTATCATGGAAATGCAATTATAGAGAAACATTCAGATGGAGAATTTACATTTATTAGACACTATTTAAATTGTAAACTGCTGTCTTGATGTAAAAATATTGAACGTTTCTCTTCTAGAGTCTCAACCACAGGAGTTCTTCATGCAGAATTGAGTGTTCTTGACTTG

Associated Phenotype:

Not determined

ZMP

Alleles

Mutation Details

Mutation Details

Mutation Details

Mutation Details