ZMP

wu:fb39e12

Ensembl ID:

ENSDARG00000076229

ZFIN ID:

ZDB-GENE-030131-681

Human Orthologue:

MKL1

Human Description:

megakaryoblastic leukemia (translocation) 1 [Source:HGNC Symbol;Acc:14334]

Mouse Orthologue:

Mkl1

Mouse Description:

MKL (megakaryoblastic leukemia)/myocardin-like 1 Gene [Source:MGI Symbol;Acc:MGI:2384495]

Alleles

There are 4 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa38884	Nonsense	Mutation detected in F1 DNA	Not yet available
sa44757	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa38884

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000109874	Nonsense	260	1200	8	17

Genomic Location (Zv9):

Chromosome 12 (position 19805642)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	12	18657803
GRCz11	12	18779677

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGATGTCTGGCTTTATTCAGTTCAAGTCCAGCACAGATCGGACCTATCAA[C/T]GATCAAAGAAACCCAAAGATAACAAGCCCAAAGTAAAGAAGCTGAAATAT

Long Flanking Sequence:

ATTATGGTCACTAATGGTACAATTTCTTATATCTGAATGTTTTTAAAATCATTATACAATCGCAGGCGAACACAAAAACACATGCAAACATAAATTATAATACAAACTTAACATTGCATATCCTGCGATGTGACGATTGCGAATAATTACATTGCGATATTGATGGTGAAACGATATATTGTGCAGCCCTACTTTACATGATCCATTGTTGTATTGGGATGCATTAAAGATCACATACCATATTTAACCAGAGTATATAATGTAGTTCCTCACTCAGGCTCCTCCACCTCTTCTTGTCACGTCTGACGCCTCTCCACCAAAAAATCTAACCAGTGAAACTAACATTTCAAACTCTTCCCGTCCACCATCAGGACATACAAAGGTAAAGTGTAAAATTATTATTTTTGAACTGATAAAAAAACAAATAAAAGGGTCATGCTCATTTTAATTTGATGTCTGGCTTTATTCAGTTCAAGTCCAGCACAGATCGGACCTATCAA[C/T]GATCAAAGAAACCCAAAGATAACAAGCCCAAAGTAAAGAAGCTGAAATATCACCAGTATATCCCGCCTGACCAGAAGAACGACCGGGAGCCACCGCCTCAGCTGGACTCCTCGTACGCCAAAATCCTCCACCAGCAGCAGCTTTTCCTTCAGCTTCAGATCATCAACCAGCAGCAGCAGCACTACAACTACCACACCATCCTACCCGCACCTCCGAAGTGAGTACAAGTGGATGTGGATTCATTTGAGTGTGTTATGAACTCGTATGCTCATTGAAGGTGCTTTATTTGATCAATAATATTTCTAGTAGTGATTATAGTGTGAATATATTTTGTTATTTAAAATAGCTGTCTGTTTTAATATATAGTAGAAAACATCTCAAGTATATCAAAATTTTTTTATTTAAGTTTTCCTAAAACTATTGAACAACACTCGCTGTCTTAAGACAATTTTAAAGAACTTTTTTTGATCCACTTTGAATGTTGACTACTATGTTTCATT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa44757

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000109874	Nonsense	312	1200	8	17

Genomic Location (Zv9):

Chromosome 12 (position 19805798)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	12	18657959
GRCz11	12	18779833

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACTCCTCGTACGCCAAAATCCTCCACCAGCAGCAGCTTTTCCTTCAGCTT[C/T]AGATCATCAACCAGCAGCAGCAGCACTACAACTACCACACCATCCTACCC

Long Flanking Sequence:

ATATTGATGGTGAAACGATATATTGTGCAGCCCTACTTTACATGATCCATTGTTGTATTGGGATGCATTAAAGATCACATACCATATTTAACCAGAGTATATAATGTAGTTCCTCACTCAGGCTCCTCCACCTCTTCTTGTCACGTCTGACGCCTCTCCACCAAAAAATCTAACCAGTGAAACTAACATTTCAAACTCTTCCCGTCCACCATCAGGACATACAAAGGTAAAGTGTAAAATTATTATTTTTGAACTGATAAAAAAACAAATAAAAGGGTCATGCTCATTTTAATTTGATGTCTGGCTTTATTCAGTTCAAGTCCAGCACAGATCGGACCTATCAACGATCAAAGAAACCCAAAGATAACAAGCCCAAAGTAAAGAAGCTGAAATATCACCAGTATATCCCGCCTGACCAGAAGAACGACCGGGAGCCACCGCCTCAGCTGGACTCCTCGTACGCCAAAATCCTCCACCAGCAGCAGCTTTTCCTTCAGCTT[C/T]AGATCATCAACCAGCAGCAGCAGCACTACAACTACCACACCATCCTACCCGCACCTCCGAAGTGAGTACAAGTGGATGTGGATTCATTTGAGTGTGTTATGAACTCGTATGCTCATTGAAGGTGCTTTATTTGATCAATAATATTTCTAGTAGTGATTATAGTGTGAATATATTTTGTTATTTAAAATAGCTGTCTGTTTTAATATATAGTAGAAAACATCTCAAGTATATCAAAATTTTTTTATTTAAGTTTTCCTAAAACTATTGAACAACACTCGCTGTCTTAAGACAATTTTAAAGAACTTTTTTTGATCCACTTTGAATGTTGACTACTATGTTTCATTATCAATGTTTTGGTGGTTACCATGCATGTTTAGCGGTCTTTAACAAAAAGAAAGATGATTTTATTTAAAATAGAAATGGTTTTTAACATTATAAATGTATTTACTTTCAGTTTTGATCAATTTAGTGTGTACTTGCTCAATATTAGTATTCATTTT

Associated Phenotype:

Not determined