Busch Lab

ZMP

polr3e

Ensembl ID:
ENSDARG00000037358
ZFIN ID:
ZDB-GENE-030131-8462
Description:
DNA-directed RNA polymerase III subunit RPC5 [Source:RefSeq peptide;Acc:NP_997919]
Human Orthologue:
POLR3E
Human Description:
polymerase (RNA) III (DNA directed) polypeptide E (80kD) [Source:HGNC Symbol;Acc:30347]
Mouse Orthologue:
Polr3e
Mouse Description:
polymerase (RNA) III (DNA directed) polypeptide E Gene [Source:MGI Symbol;Acc:MGI:1349452]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa41928 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa38864 Nonsense Mutation detected in F1 DNA Not yet available
sa21993 Nonsense Available for shipment Available now
sa24899 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa41928
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105292 Essential Splice Site 13 696 1 20
Genomic Location (Zv9):
Chromosome 12 (position 1228985)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 996343
GRCz11 12 1031930
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTCTTCATTATGGCCAGTGGAGACGATGATGATCCCATCATACAGGAGG[T/G]AAATGTAAACATGATCGTCACACTGCAGAGTTAGGCGTCTGTCTTCATCC
Long Flanking Sequence:
TGTAAATATTTGTTGGACCAAAATATGTGAGTCAATGTGTTTGAATATTTTAAAATAACAATAATTTAATAATGTTTATGTCTGTTTACTGCTGCACGATATTGGAGAAATCTGATATTCCAATGTTTTATTTTTCTGCAATTAAATATTGCGATATAAATAGTTTTAAAAGATAGTTAAATTGTCGTTTTCTAGGGAGTCTAAACTAGTATTCAGGTACAGAAATACAGTAATTAAATACAGTGGTTAACTTTAATTCAGACTCAACATTGCATACCTTGTGATGTGACTATTGTGTATGCACACATTTGCGATATTGATGCTGAAACCATATATTGTGCAGTCCTAGTTTACGTTACGCCCAGCACTGAGTAGCACAGAACTGTAATGTATTGTAACACTGTTGTTTGCAGGTTTGAATCCTCCATCAGCATCTTCTCCTCTTTCTCAAGTCTTCATTATGGCCAGTGGAGACGATGATGATCCCATCATACAGGAGG[T/G]AAATGTAAACATGATCGTCACACTGCAGAGTTAGGCGTCTGTCTTCATCCTTTCTGCTCTCTTTCTTCTGTTAGATCGATGTTTACCTGGCCAGAAGTCTGGTGGAGAAGCTCTATTTATTCCAGGTGAATATCATGACTTAATGCATGGCATAAACATCAACGTAAAGTCATCAAAGTTGCACTTATTTGATTAAAAATATAGGGATTACAACTTTAAATCATTGTTTTCTTGATGAAAATGTTATTGTTGTGATTATAGTGGTGAATAGGGTAATATCTATCACCGTACTTCCCCAGTTGATTGATTACATTAGGAACTGCAAATATATCCGTGTATTACAAGTTTTCTTAAACGTTAAGTGTTTTGGTAACACTTTAAAATAATGATTCATTAGTTAATGTATGTGCCAACATAAACAAACGGTGAGCAATATATTTATTACAGGTTTTATTTTTCTTGTGCATTAATGTAAGCAAGCATAAATTTGGATTTTAATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38864
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105292 Nonsense 153 696 6 20
Genomic Location (Zv9):
Chromosome 12 (position 1224472)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 991830
GRCz11 12 1027417
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAGACCCAGCTTCACCTATCTGGATAAAGCAGATACGAAACATCGAGAA[C/T]GAGAAGCTGCCAATGAAGGTGGGAGGATGTTTTTGGGTCACTTTCATAGT
Long Flanking Sequence:
GAAGCAGGGTTGGAACTAAACTGTGCAGGGCTTTGGCCCTCCAGGAATTGAGTTTGACACCCCTGCTCTAATGGCTAATGGACAGACGGCTGCTTCTCACTCAGGGCTGCTGTTTATGCTAATGAGGGAGAGATGGGCATTAGTGGGCGGGGCTTTCCGCCTCTGACACAGACAAAAGGAGAATGTCAATCAAAGTGTTTCTGCAGACTGCTTTATCAAGTCTGATTTTAATTAATACAATTCATGTTAGACCTAAACCATTAGACCCTGGATATATTCACACATTGCTGACACACAAATGTGTTTAAACTCCTTATAAAAGGGATTTTCGCATTATAGGTCCTCTTTAATATGATTGTTTTTCATATTGTAATTGCTGAAGTGACAGATGCATGTTTTGTCTTTAATCAGGAGAGCTCCATCTGACTCCACTGCAGGGAATCCTCCAGATGAGACCCAGCTTCACCTATCTGGATAAAGCAGATACGAAACATCGAGAA[C/T]GAGAAGCTGCCAATGAAGGTGGGAGGATGTTTTTGGGTCACTTTCATAGTTCATTTTAATGATTGCACATTAAAATCTGGTTGATTGTTATCAGTGTTATTCAGAGCATGCATGATAAGTCTATGCCGAGTTGTTAGAAATCTTCAACATAATTTACTGCTGTTGTGTAGGCTGTGAAGAAAATTATTTAATGATTTTAAAATTGTATTGTAATCAAGTGAAAAGCGTAAACTTGCATGAGTGTACATGTTATAAGTATTAAGATTAAATCTATATTGCATATATATTACAGTTATTTATTTTTTCAGTGTACGTTTTGTAGACATGCATACATTACACACATTTGTTAAAAGTTTTAAAATGCACTTTTTAAGATATGTTCAGTATACGTGCATACATTATATTGTGTGCTGGTATATATTAATAGACGATAATGTTTTTTTTTTTGTTTTTTTTTAGAATTATGACCAGTATATATTTAAAGCATTATTATTATTATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21993
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105292 Nonsense 606 696 17 20
Genomic Location (Zv9):
Chromosome 12 (position 1216105)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 983463
GRCz11 12 1019050
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGTGACGGACCGCATGCTGCAGGACACCATCCTGCACAGCCACTGCAAG[C/T]AGATCCTCGTGCCTGTAAGTACTGCAGTGTGTGTTTTTATTGAACTACTT
Long Flanking Sequence:
CATTGCTCATGTTGCGTGTTGTTTGTTGTTCTCCAGAGCCGGTTCACCTCAGTGGAGACCAGCGTCTGAAAGCGGCTCAAGAAAACGCTCAGGAGAAGCACTCCATCCTGCAGCGAGAGCTCGACGCTCACCGGTTGAAGGCTTCAAGACTTTCAGGCTCCCAAGGACCTTCCGGTGCTTCGGTCACAGTGAAGCAGGAGCCGGTGAGCGACTCTGAGGAGCCGATGGACACGGGTGCAGCGCTCACCAACGGCTCTGTCAACGGTTACCCTGCGGCCAGCTCTCCAACGTCCGATCCGCACAACGGCCATGGACAGGCCTTCACGCCGGAGCTGCAGGACTTTGTGAAAAACACCTTCAGAAAGCATTACGTTCTGTGCCTGAGCGAAGTCAAGCGGCTGTTTAACCTGCATCTGGCTAGTTTACCGAGTGGCCACGCGGCGTACGGACACGTGACGGACCGCATGCTGCAGGACACCATCCTGCACAGCCACTGCAAG[C/T]AGATCCTCGTGCCTGTAAGTACTGCAGTGTGTGTTTTTATTGAACTACTTAGAAATTAGTGCTGGACAAAGATTAATCACATTTACATACACCAGTTCTGTCTGGTTCTCGAATCTGATTGGCTGATAGCCGTGTGATATTCTGCAATAACAGCACTCGTACAGCCTCTTGTGTATTACTCCGCCCACACAGAGTGACAGCAGATTAATAAACTCACTACAGTTTGACTAATATTGCTGCTGTTGGACAACATCATGTACTTTTGAGGCTATTTTAGGCGAGAATGTAGTTGTTTAGATTGTTACTATGCAGTTTATTTATAAGGATAGTGCCTATTTTAAGTATTTGCTTTGGCATTTTCAGGATTAATTATTGTGATTTCCTGATTGCAGTAGAGAAACACTGGGAAATCTCTGTAGACTGATGGCATTTCATGCTGTTCAGCCTCATAATCTTCAGATGTGAGCAAAATCAGCTGCTTTGTCTTCACTTTAGACATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24899
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105292 Essential Splice Site 678 696 19 20
Genomic Location (Zv9):
Chromosome 12 (position 1212827)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 980185
GRCz11 12 1015772
KASP Assay ID:
554-7790.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGAGCTCGGAGACGCCGTCAACAAGACTGATGTGGACCGACTGCTCAAG[G/A]TGAACACCAGCTCAAACATCAGGAGTCTTAAAGGGACAGTGCACACAAAA
Long Flanking Sequence:
GTTTCCTCCTCAGAGCAGCGCTGCCGCAGACGAGCAGAAGGTGTTTGGCTTGTGGGAAAGCGGAGAAACCTTTGACAAGGTGGCAGTCTTATCAAAATGAATATTTTACTGTGTTTATGTTGAATGTTTGCAGTTAATCCAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTCTCTGTGTTGTGTTTGTGTCTGTATGTGCATCTCTATGTCTGTCTGTCTGTCTGTGTGTGTGCGTGCATGCATGTGTATCTTTGTGTGTGTGCATCTGTGTGTATGTATCTCTTTGTCTTTGTGTGTATATCTGTGTGTGTATGTGTGCATGTATCTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTAGCTCCGGCAGATTCTGTTCGAGATCTTCATGAAGAATTATCGCGTCAGGAGAAACGTGATCCAGACGCGTCTCACACAGGAGCTCGGAGACGCCGTCAACAAGACTGATGTGGACCGACTGCTCAAG[G/A]TGAACACCAGCTCAAACATCAGGAGTCTTAAAGGGACAGTGCACACAAAAATCCAGGCACAGTCATCATTTACTCTCCCTCGAGTGCTTTTTAATCCTGTTCGAGTCTCTTTCGTCTGTTTAAACCCAAAAGAAGATATTTTGAAGAATGCCGGAAACCTGTAACCATTGACTTCCATAGTATCTTTTTTCTTGTTATGGTTGCAGGGATTCAGCTTTCTTCTAAGTCTCTCCTTTAGTGTTGAGTGTTCAACGGAATTAAAGAAAACAAAGCATAAGAACCACTTGAGAGTAAATAGTGCGTACATTTTAATTTTTGTGTGAACTGTCCCTTTAAGATGGGTGTAAAGAGTGCAAATTCTGATGGTGGGAAGGTTAAAAAAATGGGATAAATCATAGATAACAAAGTGTGTGTGTGTGTGTGTGTTCTCAGGAGTGCTGCATTAGTCTGGGAGGGATGTGGTATCTGAAAGGCACCGTTCACTCCTGACACCCACCACT
Associated Phenotype:
Not determined