ZMP

MAP4K3 (1 of 2)

Ensembl ID:

ENSDARG00000087742

Description:

mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:6865]

Human Orthologue:

MAP4K3

Human Description:

mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:6865]

Mouse Orthologue:

Map4k3

Mouse Description:

mitogen-activated protein kinase kinase kinase kinase 3 Gene [Source:MGI Symbol;Acc:MGI:2154405]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa35117	Essential Splice Site	Available for shipment	Available now
sa11669	Nonsense	Available for shipment	Available now
sa38850	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa35117

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000101667	Essential Splice Site	104	903	4	34

Genomic Location (Zv9):

Chromosome 11 (position 31325024)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	30202386
GRCz11	11	30449570

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATATCCATGGAATACTGTGGAGGAGGTTCGCTGCAAGACATATATCACGG[T/A]AAGTTACACCGCACAAAGGTAAACAATCAACTGCAGCGCTAACTCAAACT

Long Flanking Sequence:

ACTTCAGAATTTACTACTACTTAATTTTTACGTTTACAGACTTTTTTTTATTCTGTAAACATTTTATATTTGAAAAACATTTGGATACAGCGAGATTTCACTGTTAAAAGATTGATATATATCCATATGCACAGACAGATAGTTGGGCGATCAGTTTAAGTAGGTAATAAAAGTAGTGTTTCATGTCTCGTAGGCAGCGTGTCTCCTAAATATTAGTCTAGACATTAGTGCAGGTAGAGTGCAGAAATGGAGAAGGGTGTTTTTGATGAAAGCAGGTTGCTTGTGAGTTATGACTCTGTCTCCCGCTTGCTGTGTCATGACCCAGAAAAGTGTGCATCCTTTCACTCTCCCTATGGGGCTGCCATGGGGGACTATTTCAAGACACATCGATTGAAATATAATTTGTTGGTGTTTTTCTTTCTCTGGCTTTTCAGGAGGGATAAATTATGGATATCCATGGAATACTGTGGAGGAGGTTCGCTGCAAGACATATATCACGG[T/A]AAGTTACACCGCACAAAGGTAAACAATCAACTGCAGCGCTAACTCAAACTCACTCGGTGGTCAGTATTTCAGTGCAATGCAATATCTCCTTTCCATTCATTATTTAAAGAAATATGTCACCCAGACATGAATGTTCCGTCATCATTTATTCATCCTCATCTTGTTACAAACCCTTATGATTTTATTTCCTCTGTAAAACACGACATGATTCATTTCGAAGACTGAGGAAATTCACCTGATCGCCTCCAAAATTGGTCAACATGAAGTCAAAATACTGAGGATGCTAAATTGCATCCCGAAAAGTTATAGCAAGAAGTAGGTTTTACATTCATTGACATTTATAGACTGATTTTAATTCAACATCAGGAACTGGAACTGACACCAGCAAGTGTCTCTTTGAACATTCATTGAAATCATCAGCTTATTTTGACCCGATTTGCTTCAACTTCACTCAATATAAACTCAAGGAAGGCAGAAGTAAAGCTGTGAAAGAATTTCTG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa11669

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000101667	Nonsense	195	903	9	34

Genomic Location (Zv9):

Chromosome 11 (position 31315009)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	30192371
GRCz11	11	30439555

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GCTCCAGAAGTTGCTGCTGTGGAGAGGAAAGGAGGCTACAATCATYTGWG[T/A]GATATCTGGGCTGTCGGCAKCACTGCCATTGAACTAGCTGAACTGCAACC

Long Flanking Sequence:

TTATTGTTGTATTTTATTATTTTATTAATTATTTTGTTCTTGGCAATACTTTAATTGTATCAGTAATTTTTATTAAATAGCTTGTATGCCAGTAGTTTAACGTTTTCATTTGAATAAAACAAAATAAGAAATTATTCTGATAAATATTAAGAACATAGGAATAATTATTTAATCAACCATCAAAAAAGTAACAAAAAAGTGCTAATAAATTCTCAAAAAAATAAAATTTAATTATTATTATTATTATTATTATTATAAATGTAATGTATTTTATTCTCTTGCCAGAATGATTTTGCTCTGTGGTGTTTTAACAAACCTCACAATTAATCTGTTGCATTTGATAAGTTTTTCTTTCCTCTGCTCACCTGTCCATCAGTGTAGCGTTTATACAGTATGCTGGTGAATGTACTCTGAGAAATGATTTTTGCTGTAATCTGTGTGATCAGGATGGCTCCAGAAGTTGCTGCTGTGGAGAGGAAAGGAGGCTACAATCATCTGTG[T/A]GATATCTGGGCTGTCGGCATCACTGCCATTGAACTAGCTGAACTGCAACCACCCATGTTTGACCTGCACCCAATGAGGTGAGGCTTAGCAATAGTGTCCCAGTTTAACAAGCTGAAGTACATTTGAAGTAAAAATTGTTCGCCCTCCTGTGATTTTTATTTTATTTTATTTATTTGTTTTTTTTTTTCTTTTGCAAATATTTTCCAAATGATGTTTAACAGCAAGTATGTTTCAATTATATTTTTTCTTCTGGAGAAAGTCTTATTTGTTTTATTTCAGCTAGAATAAAAGCTGTTCTTAATTTTTTTAAACCATTTTAAGGTCAAAACTATTACCCCCCTTAAGCATTTTTTTTTCCAGAACAAACCATCATTATCCAGAGATTTGCTTAAATAACCTAACTTAACCTAATAAACCTAGTTAAGCCTTTAAATGTCACTTTAAGCTGTATAGAAGTGTCTTGAAAAATATCTAGTCAAATATTGTGTACTATCATTATG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa38850

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000101667	Essential Splice Site	668	903	26	34

Genomic Location (Zv9):

Chromosome 11 (position 31254907)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	30132269
GRCz11	11	30379453

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGCCTGTTTCCATCCCGACACACAAACTGCCTGACAAAATGATTCCCAGG[T/C]GAATGTTTGCATCAGTCAAGATGTGGCCAGTTCTTAAAATGTTCATATTC

Long Flanking Sequence:

TTAGGGTAATTGGGCAAGTTATTGTATAACTATTTGTTTTGTGGAAATTTGAAAAATAATATTGCTTAAAAGGGTGATAATATTGACCTTAAAATGGGTTTAAAAATATTAAAACCTGTTTTTATTCTAGCTGAAAAAAAAACAAATAAGACTTTCTCCAGAAGAAAAAATATTATAGGAAATACAGTGAAAAAATCGTAGCACTTTTAAACATCATTTGGGAAATATTTAAAAAAGAACGAAAACGATTTTGACTTCAATTGTAGTACATATTTTTGCAGATAGAATATTTAACTTTTTGTGGACGTTCCTACTTGATGTGTCTAAAGTGCTGGCTAATGTTGTCCTGATGTTTTGACTTCTGAATCTGTGTTTCGTCAGGAAAAGCTTGTCATCTGTACTCTCACAGTCTGTCTGGTCTGTTTGAACACGCTCGACAAATGCAGAAACTGCCTGTTTCCATCCCGACACACAAACTGCCTGACAAAATGATTCCCAGG[T/C]GAATGTTTGCATCAGTCAAGATGTGGCCAGTTCTTAAAATGTTCATATTCCATTCTGTTCAATTTTTAATCTGAATTTCAGGAAGTTCTCAGTGTCCAATAAGATCCCTGAGACTAAAGGCTGTCAGAAGTGCTGTGTAGGTGAGCAGATCCTGTTATTTTCTTGTGTTTTTTTTCCTGTATTTTTTACACGACTTTGTGTCAAGCTTTCAGGTCATTTTCACCCACATCTAATTCCTTGATTCACAGGCTAAGTGACTAATTTCTTCTTGACATTTTAGGCTCATAAATGTGCATTCATGTTTTTAAACTAGAGGCCTTGTTTCTCGCACCTAGTATTAACATGCATTTTCAGTAACCCAGCCACGATTCAGCCAAGATGCATTATCGTTTACACTTGTTTTCAAATCTTGTGACCACTGATGTTTGTTTTTGATTGAAACACTATCTCTATTATTTCATCGTGCTATACATGACTTTCTTAGGAGTGCACAGTGACTT

Associated Phenotype:

Not determined