ZMP

sppl3

Ensembl ID:

ENSDARG00000025220

ZFIN IDs:

ZDB-GENE-050913-71, ZDB-GENE-050913-71

Description:

signal peptide peptidase-like 3 [Source:RefSeq peptide;Acc:NP_001015068]

Human Orthologue:

AC069214.1

Human Description:

Signal peptide peptidase-like 3 [Source:UniProtKB/Swiss-Prot;Acc:Q8TCT6]

Mouse Orthologue:

Sppl3

Mouse Description:

signal peptide peptidase 3 Gene [Source:MGI Symbol;Acc:MGI:1891433]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa34876	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa38789	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa34876

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000038780	Essential Splice Site	None	345	2	10
ENSDART00000122663	Essential Splice Site	8	382	2	10

Genomic Location (Zv9):

Chromosome 10 (position 17434804)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	17447150
GRCz11	10	17404584

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATAAAGTTGTTGTGAGAAAACACTAAATGAAAACCTCTCTTGTGTTTTCA[G/T]GGCGTACTCCCTTGTCGACTCCAGCCAGGTGTCAACCTTCCTCATCTCCA

Long Flanking Sequence:

TTTATCCAGCAAACAGACTGTCACTCGCCGGCTGTAATCATGTTTTAAGAGTTTCCTCAGTGTGCACTGTACAGTCTGACCTCTTTCTTTAAAAGCTTGTTATTTACAAAAGGCAAACGCAGGTCTCAAAAGACACTCTGCAGGGCTCCGACAGGGAGAGAATGCCGTAACACGAGACTTTTCTCATACATGGCTTAGTAACAGCTCCACCAGGCTGAGCTTTTATTCATTTTTCAACAGTTGACAGCTTGAGGTAAGAAGAGTGTGAAAAGTGCGCACGTTATGACCCAGCAAGGGTTGTACAGGGTGGCAATCTTGTATCTATTGTATGACACACTCTTCTTTTGTTGTTTTGTTGTTGTTGCTTCTTGTTTTCTTTCCTCTTTTATATCTCTGTAGAGATGTATCTTTGGTCAACCGTGTTTGAACTTCAATGTGTTCTAGAAATAAATAAAGTTGTTGTGAGAAAACACTAAATGAAAACCTCTCTTGTGTTTTCA[G/T]GGCGTACTCCCTTGTCGACTCCAGCCAGGTGTCAACCTTCCTCATCTCCATCCTCCTCATCGTCTATGGCAGCTTCAGGTCAGTACATCTTCTCACCTCAGGCTGTGGATTAGCCAGTGCTGTTTTAGTTTTACCGAATTTTGCATTTGTTTATCATATGCCTGTTTTACCTGTGCAAACATAATACTGTTTGAAGTGTTGTTGAATTTAGTTTTGTAATGAGATGTTGATGTATTTTCATTAGCAAACAGCACCATCTGTTAAACATGTAACCGACTCAACTTTTGTATGTATTTTGATCATGATAACCATGATGCAACCTAAAAACAGGTGCAGCCTAAAAACTTGAAGCATATAAATTAGGCATGGAACGATAACCATTTTCAAGGTATACCGCGTCAACAAAAGTCCTGGTTTTAAAACTTTCAAAACTTTCTTTTATAGTGTAATATCCTTTTTTTTTTTTTTTTTTTTGAGTACAACAGTTTCTCCAGCAGATA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa38789

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000038780	Nonsense	259	345	8	10
ENSDART00000122663	Nonsense	296	382	8	10

Genomic Location (Zv9):

Chromosome 10 (position 17454368)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	17466714
GRCz11	10	17424148

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGCTGTGTTTCGTGCTGCGATATGACAACTATAAAAAACAGGCCACCGGC[G/T]AAGTGCCCGGCCCTGCCAACATGTCAGGCCGCATGCAGAGGGTTTCCTAC

Long Flanking Sequence:

TGAATACCAAGTGTATCCTCAAAATACATCCATTCATTTTTAATTGCAAACCTAAAGTGTGTTTCTCATCTCACCCGCTGCTGACTGTCGAGTCCTCTTTCGTCAGTGTCAAAAATCACTCCCAAACACGCTTGCACAAGCCTGACTTCACTCTCTCTCAGCGTCTTAAAACAGCAGGGCAAGCTGCTCTGTCCGACTGACTCATCTCCATCCCTCTTCTCCTGTAGGTCTTCTTCTCCGCCTACATCTTCAACAGCAACGTGATGGTGAAAGTGGCCACACAGCCTGCAGACAACCCACTGGACGTGCTGTCACGCAAACTTCACCTGGGGCCTGGCATGGGTCGGGACGTTCCCCGTCTCTCGCTGCCCGGCAAGTTGGTGTTTCCTAGCTCCACCGGCAGCCACTTCTCCATGCTGGGCATCGGCGATATCGTCATGCCAGGCCTGCTGCTGTGTTTCGTGCTGCGATATGACAACTATAAAAAACAGGCCACCGGC[G/T]AAGTGCCCGGCCCTGCCAACATGTCAGGCCGCATGCAGAGGGTTTCCTACTTCCACTGCACCCTCATCGGTTACTTTGTTGGTGCGTATCACAAGAAAGTAGTTTGAACACACTTTTGATCTATTTGTCAATTGAGCAAACTGTTTGTCGTTCAGTTTATTGTTCTGTCTTTTTTAGTTGTGTCTGTCTGTTTATGTCTATGGTTTTGTCTGCTGTTCTGTTTGACATTCCTTCTGTCATTCTGTCTATAGTTCAGTTATTCTTGTATATCGTTGTGTCTATTTCTAGTTCTAAGATTCTCTGGTGCTATGTCTGTCTGATGATTTCTGACAGTCTATCGGTTTGTCGTTCTGTCCTATCCAGAGTGCTGGTGTTCTCAGATGTTCTGTCTGACATTAAGCAACATTCTGTCAACTGTCTGCCCGTTTTTAATAGGCTATGTTTACACTGATTTTTCTTACCTATATGTGACACAGATCTGTTTTTGTCTTGACGGTGTG

Associated Phenotype:

Not determined