ZMP
aurka
Ensembl ID:
ZFIN IDs:
Description:
serine/threonine-protein kinase 6 [Source:RefSeq peptide;Acc:NP_001003640]
Human Orthologue:
AURKA
Human Description:
aurora kinase A [Source:HGNC Symbol;Acc:11393]
Mouse Orthologue:
Aurka
Mouse Description:
aurora kinase A Gene [Source:MGI Symbol;Acc:MGI:894678]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa2294 | Nonsense | F2 line generated | Not yet available |
| sa38587 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa2294
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008224 | Nonsense | 353 | 405 | 9 | 9 |
| ENSDART00000129708 | Nonsense | 353 | 405 | 8 | 9 |
Genomic Location (Zv9):
Chromosome 6 (position 59803464)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 6 | 60144280 |
| GRCz11 | 6 | 60139189 |
KASP Assay ID:
554-2638.1 (used for ordering genotyping assays)
KASP Sequence:
AAGCACATCGTCACCATATCTCNTGTTTGTTTTTAGGTTGAGTTTACTTA[T/A]CCAGCTCATGTGAGCAAYGGCAGCAGAGACCTGATCAATCGACTACTCAA
Long Flanking Sequence:
AGGCCCCTGCTCTAAAAGGTTTTTGAAGAGGAATTAAATTTTATTTATTTATTTTTTTAAATTAAGTTTTCCCTGAGTGTTCGACCGACGGTGCGTAAGGATATATCTGCACAACAGAACTAAAATTTGAACTGTTTTTCCTTTAATTTTAAAGCTTCACATAAACATAATGCTTTCAAAACAATCCATGTTTTCACATCCACAACAATGCCATTTCAAATTTATTTTCAGTCCTCAAACTGCTGTTGTGTTTTAAACTAATTTGCAAAAAGCGTACCCTCTTTTTCTTTGTTGGGCTGAAATTAATGTAAGCTGCCTGTTAGACTATTTTCTGTCGAAATATCTTTATTTAAATGTATTTTTTTCTTTTTAGACTTTGAACTTTTACTTTTTTTTTCTTTTTTTTTTCTTTTCATTCATTGATTTTAATCGGGTATTTTTATATCCTCAAAGCACATCGTCACCATATCTCTTGTTTGTTTTTAGGTTGAGTTTACTTA[T/A]CCAGCTCATGTGAGCAACGGCAGCAGAGACCTGATCAATCGACTACTCAAGCACAACCCAATGCACAGACTCCCCATCCAGGGAGTAATGGAGCACCCGTGGGTTGTGGAAAACTCCACCAAGAAACCAACCACTTACACCGCCACCGCCAACAACTGAGGCCTGCTGGGATTACACTGAAACCTTCTCCACGCATGTGACTTTATTGGACTAATATGGCAATAAGTGTTGATGGTCTGTGCTGCCACGCTTTCACATAACTTTATGATTTGTCTGTTGTTTTTACATGTTGTGCTGTTTATGTGCTTCAGTTTGCAAGTATTTGTAAATATGTAATTAAGACAATTTGTAAAGTTGTATCCATTACTTGAAACAAATGTCATTTCTTTTATTGTAATGGCTTTTAAGAATTTGAATAAGAAACTTAATGTATTTTGTCTGTTTGGAAATAAATTCATTTTAAGAGTTTTCCAATTTACTTTTAAAAACATCTTCCAATC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38587
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008224 | None | None | 405 | 9 | 9 |
| ENSDART00000129708 | Essential Splice Site | None | 405 | 8 | 9 |
Genomic Location (Zv9):
Chromosome 6 (position 59803789)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 6 | 60144605 |
| GRCz11 | 6 | 60139514 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTTGTTTTTACATGTTGTGCTGTTTATGTGCTTCAGTTTGCAAGTATTT[G/T]TAAATATGTAATTAAGACAATTTGTAAAGTTGTATCCATTACTTGAAACA
Long Flanking Sequence:
TATTTTCTGTCGAAATATCTTTATTTAAATGTATTTTTTTCTTTTTAGACTTTGAACTTTTACTTTTTTTTTCTTTTTTTTTTCTTTTCATTCATTGATTTTAATCGGGTATTTTTATATCCTCAAAGCACATCGTCACCATATCTCTTGTTTGTTTTTAGGTTGAGTTTACTTATCCAGCTCATGTGAGCAACGGCAGCAGAGACCTGATCAATCGACTACTCAAGCACAACCCAATGCACAGACTCCCCATCCAGGGAGTAATGGAGCACCCGTGGGTTGTGGAAAACTCCACCAAGAAACCAACCACTTACACCGCCACCGCCAACAACTGAGGCCTGCTGGGATTACACTGAAACCTTCTCCACGCATGTGACTTTATTGGACTAATATGGCAATAAGTGTTGATGGTCTGTGCTGCCACGCTTTCACATAACTTTATGATTTGTCTGTTGTTTTTACATGTTGTGCTGTTTATGTGCTTCAGTTTGCAAGTATTT[G/T]TAAATATGTAATTAAGACAATTTGTAAAGTTGTATCCATTACTTGAAACAAATGTCATTTCTTTTATTGTAATGGCTTTTAAGAATTTGAATAAGAAACTTAATGTATTTTGTCTGTTTGGAAATAAATTCATTTTAAGAGTTTTCCAATTTACTTTTAAAAACATCTTCCAATCAAGTGACACGGTGGGTCAGTGGTTAGCACTGTCCACTCCCAGCAAGAAGGTCACTGGTTTGAGTCCCACTGGAGCTTGCATGTTCCGGACCTCCAGTTTCCCCCACAGTCCAATCAAGGGGGAATTTAAGAACTGGTTCTCAGCATTTATGTGTACACCCTTCACAAATCTATCTTCAGTTCATATGTTTAATAGGAAGCTCTACAATACATTTGTGCATGCATATTAGATTAGTCAGTACTGAAGTCAAATCTGGAGCTTATAAACCAAAATAACTATAATAGGCCAAAAACTAGTAAAGCCAATTTTGTTATAGAAAAATATT
Associated Phenotype:
Not determined