ZMP

her6

Ensembl ID:

ENSDARG00000006514

ZFIN ID:

ZDB-GENE-980526-144

Description:

transcription factor HES-1 [Source:RefSeq peptide;Acc:NP_571154]

Human Orthologues:

HES1, HES4

Human Descriptions:

hairy and enhancer of split 1, (Drosophila) [Source:HGNC Symbol;Acc:5192]
hairy and enhancer of split 4 (Drosophila) [Source:HGNC Symbol;Acc:24149]

Mouse Orthologue:

Hes1

Mouse Description:

hairy and enhancer of split 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:104853]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa38559	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa20748	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa38559

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000023613	Essential Splice Site	36	270	1	4
ENSDART00000114279	Essential Splice Site	99	331	2	7

The following transcripts of ENSDARG00000006514 do not overlap with this mutation:

ENSDART00000135413

Genomic Location (Zv9):

Chromosome 6 (position 36331007)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	6	36574541
GRCz11	6	36552435

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GCATGAACACTACACCTGATAAACCCAAAACGGCTTCGGAACACAGAAAG[G/A]TTGGTATTGATATTAAGCTACGAACTATAGTGCTTCAAGAAGTGATTAGA

Long Flanking Sequence:

GCCACCCGCTCAAACGCTAAACAACCAATGGAGGGGCGCCGACCACGAGCCATCCTCCCCTCGGGCCGCGTGTCCCGCGCGCTGATTGGTAGAAAGTTACTGTGGGAAAGAAAGTTTGGGAAGTTTCACACGAGCCGTTCGCGTGCAGCCGGAGATATAAATAAGACCAACACGACGCTGAGGCAGGCAGTTGCTACGACCGCTGGCGAACGGTGAAATCAGAGACTGTGACATCATTGCCGCACCAGTTGAACTCGGGACACTTCGTGCGGATATCCATTCATAACTGGAACTGTATCAGCGTACTTGACAGCGTTTACTCCACTAGAAGCAGCTGTGCGGGAGGATTTCTTTTTATAAACAAGATCACGAAAGGATACTTCCCAGAGAAGATGCCTGCCGATATCATGGAAAAAAACTCCTCTTCTCCGGTCGCCGCGACTCCGGCGAGCATGAACACTACACCTGATAAACCCAAAACGGCTTCGGAACACAGAAAG[G/A]TTGGTATTGATATTAAGCTACGAACTATAGTGCTTCAAGAAGTGATTAGACAGATTGACTCATTTTGTTTTTATTTTGCATTTTAGTCTTCTAAACCCATTATGGAGAAAAGAAGAAGAGCGAGAATCAACGAAAGCTTGGGTCAGCTGAAAACGTTAATCTTGGATGCTCTGAAAAAAGATGTAAGTACCGAAAGTCCGACTGAGTCTTTCAGTTAGGCTATATCTGGCTGGAATATTAATGCATTTCTTTATATAGCCGCATATCTAAATCAGTCTCTTTCTTCACTCTCAGAGCTCCAGACACTCTAAACTTGAGAAAGCCGACATCCTGGAGATGACAGTGAAACATCTCAGAAACATGCAGCGCGCACAAATGACCGGTAAGTCGCCAGAGTTAAAACCTTTCAGAAAATGCACCTTGCATTCTCTTTATGTAACTAATGCAATAAAATAAAGACGTTTAAGGAGCTAAAATAATTTAAGTTGAACTTAATCTAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa20748

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000023613	Essential Splice Site	68	270	2	4
ENSDART00000114279	Essential Splice Site	131	331	3	7

The following transcripts of ENSDARG00000006514 do not overlap with this mutation:

ENSDART00000135413

Genomic Location (Zv9):

Chromosome 6 (position 36330824)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	6	36574358
GRCz11	6	36552252

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAAGCTTGGGTCAGCTGAAAACGTTAATCTTGGATGCTCTGAAAAAAGAT[G/A]TAAGTACCGAAAGTCCGACTGAGTCTTTCAGTTAGGCTATATCTGGCTGG

Long Flanking Sequence:

CAGGCAGTTGCTACGACCGCTGGCGAACGGTGAAATCAGAGACTGTGACATCATTGCCGCACCAGTTGAACTCGGGACACTTCGTGCGGATATCCATTCATAACTGGAACTGTATCAGCGTACTTGACAGCGTTTACTCCACTAGAAGCAGCTGTGCGGGAGGATTTCTTTTTATAAACAAGATCACGAAAGGATACTTCCCAGAGAAGATGCCTGCCGATATCATGGAAAAAAACTCCTCTTCTCCGGTCGCCGCGACTCCGGCGAGCATGAACACTACACCTGATAAACCCAAAACGGCTTCGGAACACAGAAAGGTTGGTATTGATATTAAGCTACGAACTATAGTGCTTCAAGAAGTGATTAGACAGATTGACTCATTTTGTTTTTATTTTGCATTTTAGTCTTCTAAACCCATTATGGAGAAAAGAAGAAGAGCGAGAATCAACGAAAGCTTGGGTCAGCTGAAAACGTTAATCTTGGATGCTCTGAAAAAAGAT[G/A]TAAGTACCGAAAGTCCGACTGAGTCTTTCAGTTAGGCTATATCTGGCTGGAATATTAATGCATTTCTTTATATAGCCGCATATCTAAATCAGTCTCTTTCTTCACTCTCAGAGCTCCAGACACTCTAAACTTGAGAAAGCCGACATCCTGGAGATGACAGTGAAACATCTCAGAAACATGCAGCGCGCACAAATGACCGGTAAGTCGCCAGAGTTAAAACCTTTCAGAAAATGCACCTTGCATTCTCTTTATGTAACTAATGCAATAAAATAAAGACGTTTAAGGAGCTAAAATAATTTAAGTTGAACTTAATCTATTTTCTCGTTTACCCAACAGCTGCCCTAAACACAGATCCCACCGTTCTTGGGAAGTACCGAGCTGGATTCAGTGAATGCATGAACGAGGTTACCCGGTTCCTGTCCACATGTGAAGGGGTTAACACCGAGGTCAGGACTAGGCTGCTAGGTCACCTAGCCAGCTGCATGACACAGATCAACGCC

Associated Phenotype:

Not determined