ZMP
gfm2
Ensembl ID:
ZFIN ID:
Description:
Ribosome-releasing factor 2, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:A0JMI9]
Human Orthologue:
GFM2
Human Description:
G elongation factor, mitochondrial 2 [Source:HGNC Symbol;Acc:29682]
Mouse Orthologue:
Gfm2
Mouse Description:
G elongation factor, mitochondrial 2 Gene [Source:MGI Symbol;Acc:MGI:2444783]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa38485 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa6990 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa33647 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa38485
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000016314 | Essential Splice Site | 209 | 762 | 8 | 20 |
The following transcripts of ENSDARG00000005561 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 36202379)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 33984328 |
| GRCz11 | 5 | 34584481 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTAGACAGCATAAAGGCCAAATTAAAAGCCAACCCTGTTCTCCTTCAGG[T/G]ACTCTTTTTGAGCAACCCTTATTAAGCAACCACACTTACAAATGCAAGGA
Long Flanking Sequence:
AAAATCTGCACACGCAGAATTGGTATGGGCCTATTATATGCAAATAACAACACATTCTAACCCTAACCATATAGTACAAGCTGCTATTACTTTAAACTTAAATGTATAGTTACAATGTAACAAGAACACTAAAGTGTAGTCAAAAAGTCTATTCATTTGTAAATGGTTGTGGGGTTTTTGACCTATATTTCAGGCTCAAACCATGACTGTGTGGCGGCAGGCAGAAAAACATCAAATTCCTTGTGTGTGCTTCCTAAACAAGATGGACAAACCTGCAGCTAGGTGATGCACACAAATATTTCATTTCTTCAATTGTTTGAATATCACTCTTTAATTAGTTCAATCCTTTAAAACATTGTCAGAAAAGTAATACATGTTATTGATCTGAATGAACAACTGCTGATCACTAGGGTTTAATCTCTCTCTCATCTTTCCTAGCCTGAGGTATTCTTTAGACAGCATAAAGGCCAAATTAAAAGCCAACCCTGTTCTCCTTCAGG[T/G]ACTCTTTTTGAGCAACCCTTATTAAGCAACCACACTTACAAATGCAAGGATTCAATCTGAACACTTGGTGTCATTTGCAGATTCCCATTGGCTCTGGGAAGAGCTTTACCGGATTGGTGGACTTGATCACTAGGCAGAAAATGATGTGGCAAGGAAACGCACTCACAAACGATGGTCGTTCCTTTGAGATCAACAGCCTTCAGCCCTCGGATGACCCAAATGTGCTGCTGGCTGTCAGTGAGGCCAGAGCGGCTTTGATAGAACAGGTGAAACACAAAAAACTATTTAAAAACAAAATACATTATGGTCAATTTAGTTAGTCTCTAAATACAGTTTTATCATGCATTATTTTCCTCCTTGCATAACTTACCACCTATTTTTGGTGGAATGAAATGGTTATTTTGAATAATGCTTGTGTTCAAACAACAACAGAACTCTTATTGTCTTTCATTGGTTTAACAAAAACATTTTGGAAAATGTCAAAGTATCAAAACAACATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa6990
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000016314 | Nonsense | 367 | 762 | 12 | 20 |
The following transcripts of ENSDARG00000005561 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 36204931)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 33986880 |
| GRCz11 | 5 | 34587033 |
KASP Assay ID:
554-5290.1 (used for ordering genotyping assays)
KASP Sequence:
GGTATAAAAATGATCTGTGTGCCTTGGCATTCAAAGTGGTCCATGACAAA[C/T]AGAGGGGTCCGCTTGTGTTTGTTCGRATCTATTCAGGAAGCATGAAAGCT
Long Flanking Sequence:
TTGCCTCAACACACCTGCAAGGATGTTTCTAGAAAGCCTAGTAAGAGCTTAATTAGCTAGCCAGGTGTGTCTGATTGGGGTTGGAACTAAACTTTGCAGGACACCGGCCTTCTAGAATCGAGCTTGGGCACCCCTGGTCTAGCAAAACTAAATTTGTTGAAGGTGAAACTGAAACCAGCAGCCTCTGGGCAAATTCTCTTTATGAATCAAGTTGCAGGAGGCGGTGAGGAGAGTGACTTTAGCTCGTAAGGGTGTACCTGTGTTGTGTGGAAGCTCTCTAAAAAATAAAGGCGTTCAACCTCTGCTGGATGCCATCACTGCTTACCTTCCTGCTCCCAATGAGAGGAACCATGACCTGGTGTGAGTACACCATCCTTTAAACTTCATAGTAAGATTGTGTTTTTTTTATTGCCATTTAAAAATGCATGTACATTTGTCTGCACAGGCGCTGGTATAAAAATGATCTGTGTGCCTTGGCATTCAAAGTGGTCCATGACAAA[C/T]AGAGGGGTCCGCTTGTGTTTGTTCGAATCTATTCAGGAAGCATGAAAGCTCAGTCATCAGTGCACAACATCAACAGGAATGAAACGTAGGTTTAGTGAACATCAAATCGCATGCAGTTACTTGACAGTAAATAAGACCCTATAAATCAAGTAACAGTTTTACATTAATTTCACTATAAAAGCTGATATTTTACTTTAAATAACTGAAAGACAAGTACTTTGGTGTTTTTACAACTAATTCTTAGATTTTTTCATGCTTTCTCAAGAGTGAAGATTTGTTTTATTTAAGGTCTACCCTGAAGAACAGTATTTTGTGTGTTGTCCTCTAGGGAGAAAATGAGTCGACTTCTCTTACCTTTTGCCGATCAACAAATCGAAATCCCATCGTTGTCTGCAGGAAACATTGCACTCACTGTTGGACTCAAACAGGTAATTTAACTTCAATGGTACATAGTATAGCTGCACGATATTGGAAAATTCTAACATTGCAATATTTCTTTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa33647
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000016314 | Essential Splice Site | 560 | 762 | None | 20 |
The following transcripts of ENSDARG00000005561 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 36208691)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 33990640 |
| GRCz11 | 5 | 34590793 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGCAAGTGGCCTACAGAGAGACCATCCTGCAGTCAGCAACAGCCAAAGG[T/C]AACGCCAATGTAAACATTGTCTTCATATTTTGACTAACATATCACCTTGC
Long Flanking Sequence:
TAACCAGAAGATAATAGCTGTGCTATCTTTGTCAATCCATTGCTCTACAATTGATTTATTCTTTTATTGTTCACACTTTGCAATAAAGTTTCATTAGTTAGTGCATTCAGTAACATAAACCAATTATGAACAATACAACACAGCATTTATAAATCATAGTTCAATTTTTACTGATACATTATTAGCATCAGAATTCATGCTTGTTAACATTAAAGCACTGAACTAACAATGAACAACTCTATTTTTATTAACTAACATGAACAAATACTGTAATAAATGTAATGTTCATGTTAGTAAATGCATAGTAACTAATATAAACCTGTTGTAAAATGTTACCATTTTATGTATACACACTTACAGACAGTACTGTGTGGAATGGGAGAGCTGCACATTGAGATCATCCATGATCGCATTAAGAGAGAGTACAAAATCGAAACTCATCTTGGACCCCTGCAAGTGGCCTACAGAGAGACCATCCTGCAGTCAGCAACAGCCAAAGG[T/C]AACGCCAATGTAAACATTGTCTTCATATTTTGACTAACATATCACCTTGCTGTGGTAAAACACTAGTCAGTTCATCTGATTTGTTTGTTGCATTCACTCATTTATTGTTCAGTCTAACAGATAGTTATGTATAGTTAATATATATATGTACATATATATATATATATGTGTGTGTGTGTGTGTGTGTGTGTATATGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACGTATGCATGTATGTATGTATGTATGTATGTATGTATGTATATATATATATATATATATATGTATATATATATACACAGTATATGATCACAATCATGAGCAGTTTAATTTCTACTCAAAAGCTTGAAGTATATATATTTTATTGTAATGCAATATTGAATAAAAGTAATTAATTTCTTTAAATTAGTGCTGGACAAAGACTAATCACATCTAAAAT
Associated Phenotype:
Not determined