Busch Lab

ZMP

aacs

Ensembl ID:
ENSDARG00000012468
ZFIN ID:
ZDB-GENE-040426-903
Description:
Acetoacetyl-CoA synthetase [Source:UniProtKB/Swiss-Prot;Acc:A3QK15]
Human Orthologue:
AACS
Human Description:
acetoacetyl-CoA synthetase [Source:HGNC Symbol;Acc:21298]
Mouse Orthologue:
Aacs
Mouse Description:
acetoacetyl-CoA synthetase Gene [Source:MGI Symbol;Acc:MGI:1926144]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa20372 Nonsense Available for shipment Available now
sa40383 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa38456 Nonsense Mutation detected in F1 DNA Not yet available
sa33560 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa20372
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000010101 Nonsense 31 673 1 18
ENSDART00000099434 Nonsense 31 659 1 19
Genomic Location (Zv9):
Chromosome 5 (position 20681071)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 18393530
GRCz11 5 18897322
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTCGAAGGTGCTCTGGTACCCGGACTCCAAGCGAAACACACAGACGGAC[C/T]GATTCCGAACTCTGGTTAACCGGGAATTCGGCTTGAACCTGGGTGAGTAG
Long Flanking Sequence:
AACATCCTCAATATAATCTGACAGATGAATCAGACAGACCTTCCGCCAGGGTACGTGCAAGTCAGTAATTGCAAATGCTAGTTCATTAATCACAAATATATATAAAAATAATAGAAAATAAATTAAAAAAAGGAAAAAAATCTGAATCATCCATAGATTTTTGTGTAGAAACCGAAGCACTACATTAGTCGCGGAATAACACATGGAGGTTGTCAGGACGCAGTGCGGTTGCGCGGTAGGCGGGGCTTCCGCTGCTGCTGGTTGATTATGTTCGGCTGACGCTCGGAAGTGACCCATGTGTCTGACCTGCACCAATACACGATCACCGGATCGGCCCGTCCAACTCGCGTAGTGCGATTCTTTGAGTCTTCATAGCTTATTCACGATACGTTGGCGCGTGTCATCCGATCATGTCTAAAGACACGGAGGCCAAGAGCGAGGAGATTATGGAGTCGAAGGTGCTCTGGTACCCGGACTCCAAGCGAAACACACAGACGGAC[C/T]GATTCCGAACTCTGGTTAACCGGGAATTCGGCTTGAACCTGGGTGAGTAGAGAGTCAGCCTGGGCTTGGTTGAATGTAGACTAACTACACACCCCTTATTCTCCAGGAAAACAAAGCATAGTACTATGGTTTGGTCTTAATCGCATTACTAGCTCATCCTAGGCTTGTCATGTTATGTCATGGTCACATTTAAGCAAAAACAGAGCTCTTTATTTTTTGCCCACTATATTTGATCCAGGATCCATTTTATATGTTTCATCTAGAAATAGATGCCTGACCACGTATTTCCAGTTATTCATGCATGCCAGTCTGCTAAATCTCAATGCTTGCATTAGACATAAGAAGTTGCAAAACCAGAATTTCAGATCAGACCTAGAATTTACACTGACAGCATGATTTATTTCCTTATGTCACTCTCATCTCTGTTCCTGTTATACAATTATATTTTGTCTCACAAATTTGTACATTTTTCCTAATAGTAAATGGTATATCCTTGTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40383
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000010101 Essential Splice Site 45 673 1 18
ENSDART00000099434 Essential Splice Site 45 659 1 19
Genomic Location (Zv9):
Chromosome 5 (position 20681027)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 18393486
GRCz11 5 18897278
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGGACCGATTCCGAACTCTGGTTAACCGGGAATTCGGCTTGAACCTGGG[T/C]GAGTAGAGAGTCAGCCTGGGCTTGGTTGAATGTAGACTAACTACACACCC
Long Flanking Sequence:
GCCAGGGTACGTGCAAGTCAGTAATTGCAAATGCTAGTTCATTAATCACAAATATATATAAAAATAATAGAAAATAAATTAAAAAAAGGAAAAAAATCTGAATCATCCATAGATTTTTGTGTAGAAACCGAAGCACTACATTAGTCGCGGAATAACACATGGAGGTTGTCAGGACGCAGTGCGGTTGCGCGGTAGGCGGGGCTTCCGCTGCTGCTGGTTGATTATGTTCGGCTGACGCTCGGAAGTGACCCATGTGTCTGACCTGCACCAATACACGATCACCGGATCGGCCCGTCCAACTCGCGTAGTGCGATTCTTTGAGTCTTCATAGCTTATTCACGATACGTTGGCGCGTGTCATCCGATCATGTCTAAAGACACGGAGGCCAAGAGCGAGGAGATTATGGAGTCGAAGGTGCTCTGGTACCCGGACTCCAAGCGAAACACACAGACGGACCGATTCCGAACTCTGGTTAACCGGGAATTCGGCTTGAACCTGGG[T/C]GAGTAGAGAGTCAGCCTGGGCTTGGTTGAATGTAGACTAACTACACACCCCTTATTCTCCAGGAAAACAAAGCATAGTACTATGGTTTGGTCTTAATCGCATTACTAGCTCATCCTAGGCTTGTCATGTTATGTCATGGTCACATTTAAGCAAAAACAGAGCTCTTTATTTTTTGCCCACTATATTTGATCCAGGATCCATTTTATATGTTTCATCTAGAAATAGATGCCTGACCACGTATTTCCAGTTATTCATGCATGCCAGTCTGCTAAATCTCAATGCTTGCATTAGACATAAGAAGTTGCAAAACCAGAATTTCAGATCAGACCTAGAATTTACACTGACAGCATGATTTATTTCCTTATGTCACTCTCATCTCTGTTCCTGTTATACAATTATATTTTGTCTCACAAATTTGTACATTTTTCCTAATAGTAAATGGTATATCCTTGTGTTGCTGATGTTTATGCTTTTAATAAATACAACAGTTAGTCTTATAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38456
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000010101 Nonsense 420 673 12 18
ENSDART00000099434 Nonsense 406 659 13 19
Genomic Location (Zv9):
Chromosome 5 (position 20627711)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 18340170
GRCz11 5 18843962
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCCTCCACACACTCCTGTCTACAGGATCCCCACTGAAGCCCCAGAGCTA[T/A]GAATATGTGTACAGCTGTATTAAGAACAACGTGCTCCTGGGATCTATATC
Long Flanking Sequence:
GACTCTGATAACCAGGGCGAGAGACCCTCTCTACACGGGACCCCAGGCGGGTGGCCTGGCATGTCGCCTGCATACATTTTTCAGCACAGTTTAATGCGCTTACTAATTCTGATCACTGTGAACCAACCCATCTGCCTCCAGAATACAAACCAAGCTGAGCTTAGCTGTATTATTCAAGACTGAATTTACAACAAATCCAAACATGCTTGAATTTTTATTGAAGATTGATAGTGTCACTGCTGTTGATTACTGAATGAATATGTGGGCATCTCAAGCTGATTTGAATGTACAGTATGTGGCCATTATTGTTGTTGTTTTTTTATGTTGTACAAGCTTTTTTTTTTCATTAAATGCAGTGTTTTTTTTACATCGTGAGTCTTAAGCAGTTTTTTTTTAATTAATAGATTGTGTAATTCTTTTCTGTTTACAGCAAGCACACACAGCCTGCAGACCCTCCACACACTCCTGTCTACAGGATCCCCACTGAAGCCCCAGAGCTA[T/A]GAATATGTGTACAGCTGTATTAAGAACAACGTGCTCCTGGGATCTATATCAGGTGTGTTCTCCTTTATCTCTTTCCATTTCTTTTTCCTTCTTTCATTTGCTGCTTTACTTCTTTATTTCCGTTGTCTGCTTTTTATTTATTTATTTTTTTGTCCTTCCTGCATTTTATTACACAACTCGTTTTCTTTCCTCAGTTATTAACCAACATTCCTTCTTCTCTTCATATTTTTTTACTTTTATGCTTTACCTGCATCTTTTTCTTCCTACATTCCTTTTTAATATTTCCTCTTTCGTTGTTTCTTTCTACGGGTTTTTCTCTCTGTTTTTCAGTTACTCTCCTGACTCCATGCATTCCATTTGTTTGCTAATTTTCCTTTCTTTCCAGTTTCAGCATTTCCTGTCCTTTTCCCTCTTCTTTAGCTCTTCCTTCCTTCTGTCCCTCTTCAATGCCACCTTTCTTTCCTTATTTTTACCATATTTCTTTATTTTCCTTCTCCTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33560
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000010101 Nonsense 588 673 17 18
ENSDART00000099434 Nonsense 574 659 18 19
Genomic Location (Zv9):
Chromosome 5 (position 20612153)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 18324612
GRCz11 5 18828404
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGTGTCCCTCAGTACAACAGTGACGGAGAAGAGAGGGTGATTCTGTTTT[T/A]GAAAATGGGACCCAATAAGAGCTTTAGCCAGGAGCTAGTAGGAAAGATCC
Long Flanking Sequence:
GATGTCTCCTTTCTCTCTCACACCCCTTGCAGGTCCTTCAGTCTCTGCTAATGAGCTAATGATCTGAATCATCTGCTGTTTACATCAATATAGTGGATGTTTACATCAATATAGTGTACTTTTTCTGAAACCGTAAAACAATAATCAATATTTTTACGTTAACATGAAGGTTGCGTTTAGTTTTTCTGTAGGGTTAGATGCTATTAACATGGGTAATTTAATAATACAAATAATCCTCATTAACTTCAAGTCGAGCTGTATCCCTTCTAGCAGCAAATTGTGTTGTTTGACATCATTTTCAGTAAGTAGTTTGAACAAGGTGCAAGTGTAATTTCTTTGAGTGTATATGTGCTAACATTATACAGTAGCAAGACATTTTGTTAAGACCCCTGTTATGCTCTCTCTCTCTCTCTCGCCAGTTGAAGCCTTTGACGAAGTGTCCGACAGCCTTTGTGTCCCTCAGTACAACAGTGACGGAGAAGAGAGGGTGATTCTGTTTT[T/A]GAAAATGGGACCCAATAAGAGCTTTAGCCAGGAGCTAGTAGGAAAGATCCGTGGTGCTATTAGAGTAGCTCTCTCTGCACGACACGTACCAGCCTTGATACTGGAGACCAAAGACATCCCGGTGAGCACGGCTGCACATCTTTTTTTTTTTTTTTTGCTTGTCCTCTCTCTGCCTCCATTTTCTGCACTTTTCCACCTGACTGACTTTAAATTTGCTTTGCCCGCAGTACACTATCAGCGGAAAGAAGGTGGAAGTTGCAGTAAAGCAGGTGATTGCAGGTAAGGAAGTCACTCAGCGAGGGGCCTTCTCAAACCCAGACTCTTTGGACCTTTACAAGAACCTACCTGAACTCCAGAACTTCTGAGGTACTCATGCAGATTCCGTTCAAAGGAACGTCTATTGGACCATTTGGAGGGAATTAAACATTGAAGCTTTTTCTGCACATTGTGGCACTTACGCAAACTTCACTGGAGCCAATGGAGTTTGAACACGCAACACC
Associated Phenotype:
Not determined