ZMP

si:dkey-3n7.4

Ensembl ID:

ENSDARG00000045864

ZFIN ID:

ZDB-GENE-041210-356

Description:

Novel protein similar to vertebrate tropomodulin 1 (TMOD1) [Source:UniProtKB/TrEMBL;Acc:Q5RGR5]

Human Orthologue:

LMOD2

Human Description:

leiomodin 2 (cardiac) [Source:HGNC Symbol;Acc:6648]

Mouse Orthologue:

Lmod2

Mouse Description:

leiomodin 2 (cardiac) Gene [Source:MGI Symbol;Acc:MGI:2135672]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa20187	Nonsense	Available for shipment	Available now
sa38418	Essential Splice Site, Missense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa20187

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000067409	Nonsense	47	596	1	3
ENSDART00000138221	Nonsense	57	604	1	2

Genomic Location (Zv9):

Chromosome 4 (position 3991732)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	4110345
GRCz11	4	4119258

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACCAAGAGGCCATGAGTACATTCGGCTACCGTCGGGAACTCAGTAAGTAC[G/T]AGGATTTGGATGAAGATGAGCTGTTGGCTTCACTCACAGCCGAGGAGCTC

Long Flanking Sequence:

TTAAAGCCTTTCTAGGTTGTCCGATTCTAAACAGCTAAAATGAACCAAAGATTCCCTTGATGTACCTTTAATGTTAAAGCAACTCCTTTTTGTATCTAAGTCTTTACCTTCTTGCTGCAACTTACTATTATAAGGATATGACCATCTCTCTCTAAGTCTATCTGCTTATTTTGGACATGAACAATGCAGTCAGCACTCATTGACAGGCCTCGCTGTGGCCATGTTGTGAGCTCACATGCTTTTTGCAGCTCTTTCTGATTGACTCCTGCCTCCCAAAAAAGCAACGGCATCATAGGCTGGGGCTTTGTACCACGTCTCTCTGATCCCGCTCTTAAGACCCCTCCAGCTGCCCACCACAGCAGATGAGCACTCACTCTCACTTGAACCACTCGAAGGATCCCAGAACGCTCAAAACATCTGATGCACCAACGCTGAGACAAAACCAAGACTACCAAGAGGCCATGAGTACATTCGGCTACCGTCGGGAACTCAGTAAGTAC[G/T]AGGATTTGGATGAAGATGAGCTGTTGGCTTCACTCACAGCCGAGGAGCTCCAGGAGCTGGAGAAGGAGTTGGCTGATATTGACCCAGATGACAATCTCCCTATCGGATTGCGGCAAAGAGATCAGACCGCCAAGACTCCCACCGGTACATTCAGTAGGGAAGCTCTGATGAAATACTGGGAAAATGAGACGCGAAAACTGCTGGAGGAGGAAAGGATTGGATCTACAAGCCCAGGAGAGGTCAGTGCTAACAATCTTAAACACTTCCAATGGTGTCAGAAAAAAACAGTACCTTGATTGTTTTAAAAGATTGTCAATGGAAAGGTATGCTTTCAGTGGATACCTTTGTACTCAATACATTTGAGTAGTAGTATGTAGCCTACGCTTACAGACAAATACTGTTCTTGGAGGTCCACTATCATGCATATTATAACCGTTATATAATTAAACACACCTGAAACAACGAAGCAAGGTCTTACTGGCAATACAAGAAACTTTCAA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa38418

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site, Missense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000067409	Essential Splice Site	588	596	2	3
ENSDART00000138221	Missense	599	604	2	2

Genomic Location (Zv9):

Chromosome 4 (position 3989494)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	4108107
GRCz11	4	4117020

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATGAACTCATGGCCGCCATCAGAGGCAGCAGCGTCAGAAATCTCAGAAGG[G/A]TGAGTATCACAAAATCTGTCAGGCTCTGTTCTGAAACAGTCAACTTTCTT

Long Flanking Sequence:

GTCTGCAGAATGGAGGTACAGCAACACCCACAAATCCAAGAACTGTTGCTCTTCAGAAGAGCACGAGCACTTCTTCTCCTCACAGCTCGCCTCGGAGTTCGCCATGGTCATCTCCAAAGCTACCACATGTTGACATGGCCAAGAAAAATGCTCCCCCTGCTCCTCCACCACCACCACCACCTCCACCACCTCCTCCTCCTCCACCCCCAAAAGCCTCCCTCTCAGAAAATAAACCTCCCTCCAGAATGATTGCTGAGGTGATCAAAAGGCAAGAGGAGACTTCCAAGAAACAGCAACATGGTCCCACCAAATCCAAATCCAAAAAGGGCAAAAAGAGGCCTCCAAATCAAACAGAGACGGACAGCATATTAAAGGAACTTAAGAACGCTTTGAGACCCATCAATGACAGAGAAAACTCCAGACCATCCACACCTCAGCGCTGTGCTCATGATGAACTCATGGCCGCCATCAGAGGCAGCAGCGTCAGAAATCTCAGAAGG[G/A]TGAGTATCACAAAATCTGTCAGGCTCTGTTCTGAAACAGTCAACTTTCTTGTCATCTAGTGACTTCTTGCTTGAAATGAAGTCTTAAATGACTTACTTGTAAATCTTAATAAAGACAGCGACCTATACATCTACCACACTGTTGATACACCACACCTATACATCTGAGAATCACTGTTGATTTCAATTAGGTTAGGATTAGTATGTTGCTAAGCTAATGCAAACAGTTAATATACATTGGGTACATATATTAATGGATCCAGTGGGATCAGATTCATGCGATGGTTTCTTTGAGGCTGGAAAAAAGATAGCTTATACTGTCTTTGTTTGGAACAGAGCCACAGATATTCCTGTCAATGTTTTTATGCTATTTAGATGGGGTTAAAGGCTAAATTAAATAAAAAAGCGTAATATCTATTTTGCTAGCGCGCATTGTACTTCCTAAGGTGAACAATTAATCCATGCCAATCAATAAAAAAGTTTGTTATAATGAAATAAGCT

Associated Phenotype:

Not determined