ZMP

pdpk1a

Ensembl ID:

ENSDARG00000062304

ZFIN ID:

ZDB-GENE-061013-109

Description:

3-phosphoinositide-dependent protein kinase 1 [Source:RefSeq peptide;Acc:NP_001070812]

Human Orthologues:

AC141586.1, PDPK1

Human Descriptions:

3-phosphoinositide dependent protein kinase-1 [Source:HGNC Symbol;Acc:8816]
Putative 3-phosphoinositide-dependent protein kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q6A1A2]

Mouse Orthologue:

Pdpk1

Mouse Description:

3-phosphoinositide dependent protein kinase 1 Gene [Source:MGI Symbol;Acc:MGI:1338068]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa5221	Essential Splice Site	F2 line generated	Not yet available
sa20114	Essential Splice Site	Available for shipment	Available now
sa38407	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa5221

Status:

F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000102245	Essential Splice Site	90	536	1	13

Genomic Location (Zv9):

Chromosome 3 (position 45336265)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	47345818
GRCz11	3	45298152

KASP Assay ID:

554-3499.1 (used for ordering genotyping assays)

KASP Sequence:

AGGAGGACTTCAGCTTTGGCAAAATTTTAGGAGAGGGCTCCTTTTCAACG[G/A]TGGGTGATTTTGCTGTTTTCAATAGCCCAGGTAGCAGATATTATGAAAYA

Long Flanking Sequence:

GTTGTGCACAAAAAGAAAAAAAAAAAGATGTTTTTGTCACTTCGACAGGGTAAATATTTTGCGCTCTCTGCAGCGTAAACAAAGGCAGGTCTGAGTGAATGAATTTGAGTACTCGTAATCCTGGCTGAACACAAACAGCCCTCCCCTCTGCGGAAGCTCTACTGTACTTTATCAGCTGCTGGTTTTACTGCTTCTAAGGTGGTTTGGTTCCTCATTGCACACGCACCCGCATGTCTGACTCTGTGTCATGTTTGCTTTGTGTGTGTGTGTGTGTTTTGCTCGTTCAGTACGATGCTGCTCTCATCCAGCCTAGCGTGGCGTTGCGTTCCTGTGCTTCTTCATCAATGGTAAGGACTCAGCTGAACTCCAGGCTTCCTCAGCATCTCGGCATGGAGGTCCGTGGGGGGGAGTCCAGCACGCCTGCTCTCAAGCCTCCGCAATCATTCAAGAAGGAGGACTTCAGCTTTGGCAAAATTTTAGGAGAGGGCTCCTTTTCAACG[G/A]TGGGTGATTTTGCTGTTTTCAATAGCCCAGGTAGCAGATATTATGAAACAAAAACATACATGGAGAGATGTATTGTAAACTGACAGCTATTATTAGTAGTTGATTTGCTGTTGTAAGTTTGGTTTCATTTATTTGTTCAGACTCTCAAAAATGTGATTCTTTCCAGAACAAAATAATAATAATTAATGCTGCAAGCAGCAATGAAAGGGACCTCGCATTTAATTGATGTAATTAAATCATCTATGATTAATTATTTATGCTGTAAATATAGTATTTAGACAGATGTATAGTATAGTATAGTATAGTATAGTATAGTATAGTATAGTATAGTATAGTATAGTATAGTATAGTATATAATGAGCCTGTTTGCCACACCCACTTCTGAACCCCATATCAAACGTAAATTTTTGCCACTTCTGGTGTGTGTGCAAACTTTTATGAGTTTCTTTGCATGTTCAGACTCTCAAAATTTGATTTATTTCAGAACAAACAAAAATAAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa20114

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000102245	Essential Splice Site	312	536	8	13

Genomic Location (Zv9):

Chromosome 3 (position 45329942)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	47339495
GRCz11	3	45291829

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCCTGAGAAGTTCTTCCCAAAAGCTAAAGATCTGGTCCAGCGTCTGTTGG[T/C]AATCATGTTTGTTTTCATGATACATGCTTTCGGTTTGTTTTGCATGGTGG

Long Flanking Sequence:

GTGAGTTACTGATCACTTGGGTTTTGGTTCAATCAAACATTGTGAAATATGTCACGATGGCATTCTGCACTGTAGCTGAAGAGCTGGTGGTTGATCACTGGTTGTAATTGCAGTTTTTGAAAACATGGTGTGAAATAACAGGAAGTGTTGGCTTTGGTGTTTATGACTTGTTTGTGTAGACAGTACAGAGGGCTTCTGAGGAAACCCCAACCACCGGGTCACATGACCCGCCTGTCGTTTTTAGTTACATTACAACCAATATACTGGCCTGGACGACCGTTGAAAACAAAACACTCCGCCACGTGACTAAATTTCACCCGTTGTTTGTCTCGAGCTGTGTAAAAACAGTGAAAGCTGGTATTGATTCACTACTGTTAGTCATTTACTTTTATCTTTTAATAGGAACGAGTACTTGATTTTCCAGAAGATAATAAAGCTGGAATATGAATTCCCTGAGAAGTTCTTCCCAAAAGCTAAAGATCTGGTCCAGCGTCTGTTGG[T/C]AATCATGTTTGTTTTCATGATACATGCTTTCGGTTTGTTTTGCATGGTGGTGTTGAAGGAGATTCATTGTTTTTTCCTGTGTCTTTCAGTCTTTGGACCCTAGAAAGCGGCTGGGATGTGAGGAAATGGGAGGGTTCGGTCCGCTGAAAGGCCACATGTTCTTTGAGACTGTCTCATGGGAGAACCTGCCGCTTCAGACTCCACCCAAACTGACCCCTTACCTGCCAGCCATGGCTGAGGATGATGAAGACTACTATGGCAATGTTAGTTCAATTTATCAGACCCGTTATTCCCAAACTGTGCTAAAATTTAAATATTTAGCATTATGTATCTGGTTGATTTTTTTTTTTATTATCATTTTGAAATGCTTATTTAATTTATTTTATTGCATTTTATTTTATTTTATTGCATTTTATTTAGCGGTTTGTGTGCATTTTTGCTTTTTCTATTTTGAATGTTTTTATTTTTGGTTGTATGATTTTGTTTATTTGTTTATTTTG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa38407

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000102245	Essential Splice Site	456	536	12	13

Genomic Location (Zv9):

Chromosome 3 (position 45326438)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	47335991
GRCz11	3	45288325

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTTTGACTGCAGTTGGTAATAACAGCTTTTTTCTTGTTTGTTGTTGTCAC[A/T]GGGGCTGTTTGCTCGACGCCGTCAGCTTTTACTAACTGAAGGACCGCATC

Long Flanking Sequence:

ATAACCTATATAAATATATGATGGTTTCTATTGTTTGTATGTTTTTCTTCAGCAGGGTCATCTTGTAGTGACAGCACATTTTGTTATTGTACACAGTAATGGGGCGCGTGCATGCGCGTATGTGCTAATAATGATCTCTTTATCTCTCACATTTCCTGTTAGCTTTTTATAGCATGTTGTAAAAGGAACTCTTGATCATTATAGTTCTGTTTTCAATCGGTCAACAACACAAGTGCCACTAACTGCTGGCTTGTTATTCATTAACATGTCTTTTTTTTCTGTCTTCAAGGCACCAGTTTGTCGAAAATAACTTGATATATAAAATGGGACCAGTTGACAAAAGAAAGGTAACGTTTTTTTTTTCTTTGTCTCTCATATCTAGAGTCAAAAACAGGTGCATGACTGCTTGATTTCTTTAAAGAGTCGAGTGAGTAAATAAATAGCGCCCTCTTTTGACTGCAGTTGGTAATAACAGCTTTTTTCTTGTTTGTTGTTGTCAC[A/T]GGGGCTGTTTGCTCGACGCCGTCAGCTTTTACTAACTGAAGGACCGCATCTGTATTATGTGGATCCTGTTAATAAAGTACTAAAGGGGGAAATTCCGTGGTCTCCAGAATTGCGTCCTGAGGCCAAGAATTTCAAGACGTTTTTTGTCCACACGGTAAAATACTGATATACTTATAGTTTCCTCATTGCATATTATTTGTGTAACACTCATCTTCTCTAGCAGTTTAGTCATGGTTTTAAATCAATTTTCATGGTAAATAATATTTGATAAATGCATCAAACTGGATCTGGGTTTCCACAGATTTTGTATGCTTGGAGGAAGTTGGTTTTGTAATAAACAAGGAATATGGCAAGAACAGTAAACAATACTCTTGTAATCAAATTAAGCTATATTTAAAGCTACAATCTTTAACTTTGTTTTAGTTAAGTATGATCTAAAATTCAGTGAGTACATAAACAGCCAATGTTCAAAACTGTCTCCTTTATACCAATTCACAGTG

Associated Phenotype:

Not determined