Busch Lab

ZMP

slkb

Ensembl ID:
ENSDARG00000012574
ZFIN ID:
ZDB-GENE-030131-1684
Description:
STE20-like kinase b (slkb), non-coding RNA [Source:RefSeq DNA;Acc:NR_023330]
Human Orthologue:
SLK
Human Description:
STE20-like kinase [Source:HGNC Symbol;Acc:11088]
Mouse Orthologue:
Slk
Mouse Description:
STE20-like kinase (yeast) Gene [Source:MGI Symbol;Acc:MGI:103241]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa38292 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa25664 Nonsense Mutation detected in F1 DNA Not yet available
sa39683 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38292
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017965 Essential Splice Site 261 1132 6 28
ENSDART00000134399 Essential Splice Site 261 969 6 19
Genomic Location (Zv9):
Chromosome 1 (position 50141714)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 48990895
GRCz11 1 49635315
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAAGATCGCCAAAGCTGAGCCTCCTACTCTACTACAGCCCTCCAAATGG[T/C]ACCAAAAAACATGCTTGTGATTGATATAGAACAGACCGTTGGTTTTTGAA
Long Flanking Sequence:
ATTTCAAGCTAGCATGTAACGATGTGGAGGCTTAAGCCACAAAATCATTGTATTCCATCATTGAATTTAAAAGCAAGCATGTTTATTTTGGAAAAACTACTCTTTTTCAGGCAGATTGATTCCTAACAAGCACATTTTCTTTATCTTTCAGCGGATTTTGGAGTGTCTGCCAAGAACACGAAGACTGTTCAGCGAAGAGACTCTTTCATTGGAACCCCTTACTGGTGAGTTTACCATACCAGCTTCTTGCACTGCTACACATTGGCATTAGAAACATGCTGATGTCTCTGGGTTTGTCCTTCAGGATGGCTCCAGAGGTGGTGATGTGCGAGACGTCGAAGGACAGGCCGTATGACTATAAGGCTGATATCTGGTCTCTGGGAATCACTCTGATTGAACTGGCTCAGATCGAACCTCCAAACCACGAGATGAACCCGATGAGAGTCCTGCTGAAGATCGCCAAAGCTGAGCCTCCTACTCTACTACAGCCCTCCAAATGG[T/C]ACCAAAAAACATGCTTGTGATTGATATAGAACAGACCGTTGGTTTTTGAACATACATATATTTTTTTATATTAATGTAAAATTGTAATATTGATTTTTTTTTTCTTTAAAACTATTCAATTGTCTTAATTAATAAAACCGTAAATAAGCTTTGGTTTCTCACAATACATGCCAAATACATGCACTGTAGGAGAATTGGGTAAGCTAAATTGTTCATAGTGTATGTGTGTGAATGAGAGTGTATGGGTGTTTTTCACAGTGATGGGTTGCAGCTGAAAAGGCATCCGCTGTGTAAAACATATGATGGATAAGTTGGCGGTTCATTCCGCTGTGGTAACCCCTGATTAATAAAGGGACTAAGCCGAAAAGAAAGTGAATGAATGAATGAAAGCAGTAAATTATATTACTGCATATTTTGCCAATGCAAAAAGCTTCACAAAGTTGAAATATGGTTTAAAATAAATGTAACAAATAAAATAGATTATATGCAAGTTAAGATGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25664
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017965 Nonsense 611 1132 18 28
ENSDART00000134399 None None 969 None 19
Genomic Location (Zv9):
Chromosome 1 (position 50133048)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 48982229
GRCz11 1 49626649
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTACCAATAAATAAACAAATTTTTAAATTAGCTTTTTTTCTAGGGAAATA[T/G]TACAATATTACAAAAGTTATTATCGCAGTACTCAGCAACATCATCTATTC
Long Flanking Sequence:
TTTTCCCTTACGTCTTTCTTTCTTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCATTTATTTATGTATTTATTTATTTACTTTTCGTTTAAGCTTTTTTCTTTTCTTTTACCCCATTTCTTTTAGTTTTTATCCTTTCTCTCTTTCCTTCCTTCTTTCTTACTTTATTTATTTTAGTTTCTATCCTTTCTTTCTTTCTTTAACTTTTTAATTTCTTTCTTTTTACTTTTTATTTATCTTTCTTTTTTCTTTCACTTTTTTTTGCTTTTTTTTTGTCTTTTTTCTCTTTCTCCTTTTTTTCTTTCTTTTTTTCTTTCTTTCTTTCTTTCTTTCTTTCATCTGAATTAGATTTAATTAAATCATGAAAACAATTATTACCTGTTTTTTTACCAATAAATAAACAAATTTTTAAATTAGCTTTTTTTCTAGGGAAATA[T/G]TACAATATTACAAAAGTTATTATCGCAGTACTCAGCAACATCATCTATTCCAGTATCGTGCAGCTCTACTTAGTTTGACATGTATTGCTTTCTGTCGACAGAGAAAGCAGTGATCGAGGAGTCCAGTAAAGCAGTGGCTCCATCATCTCCAGTGCCAGAGAAAGAGAAGAAGGAGAAGCTTGAGGACGAGCAGAAGCAGAGCCCAGTGAAACCCCATTATGTGAAGAAAGAGGACTCCGATTCGGGCATCAGCTCTACAACTGACACCAGCAGCAACAGCAGCAGTATAGACCTCAACCTGTCCATCTCCAGCTTCATCAGCAAATCCAAGGAGATGGGAACCAACTCACAGCAGGTCAGAAACGCTACTGATGCTGAGAGTCTCTGATCATATAGTGACTATAAAAGCATTTCAGGGGAATAAAAAATGACTTTAAAGTGGTTCAGTGAATCAGTTTCAAACTACGAAATGCTAAAAAAAATTTTTGATAAAAAAAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39683
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017965 Essential Splice Site 795 1132 21 28
ENSDART00000134399 Essential Splice Site 632 969 12 19
Genomic Location (Zv9):
Chromosome 1 (position 50129323)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 48978504
GRCz11 1 49622924
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAGCAGCAGAGAGATCAGATCTGCCGACGCTTCGAACACGAGACCACGG[T/C]CAGACACCACATCACACACACTTGTATATGTGGTTTATGATGCGTTGGCG
Long Flanking Sequence:
CTGAGTAGTATTAAGTACCCATGAATATACTGGGGCATTAGGACCCACACAGACTGCAGGTTAGGTGCCCCCTGCTGGCCTCACTAACACCACTTCCGGCAGTAACCTAGCTTTCCCATGTGGTCTCCCATCCAGGTACTGACCAAGCGCAGCCCTGCTTAGCTTCAGTGGGCGACCATGTGAGAGTTGCAGAGAGCTAGCTGCCGGTAAACTTGTCGCAGTTTGCTTCCTTGTTTTAGATTTTTTTCCATATTCAATATCTGGTTTGTTAGTGAATTAATTAGTGAAAGCTAATAGCGAAGGTTCCTCCATCCACACTGTGTGTGTATATGTATTGTTGGCTCAGTTTCAGAGTGTGTGATGTGTGTGTTGCAGGCGTCAGGAGCTGCGAGAGCTGAGACTCCTGCAGAAGGAAGAGCAGAGAGCACAACAACAGCTCAGCAACAAACTCCAGCAGCAGAGAGATCAGATCTGCCGACGCTTCGAACACGAGACCACGG[T/C]CAGACACCACATCACACACACTTGTATATGTGGTTTATGATGCGTTGGCGTAATATGTTTTATACCATAAAATATGTATTATATGGTTTTGAAGTACTTATATTGACCTTATTCTGCAATGTCGGAAGTCTTTTCATTTTTTAAAGTGGTTTAAATCAGGGGGCTCAACCCTGTTCCTGGAGATCTACCTTCCTGTAGATTTCAGTTGCTACCCATTTCAAACACACCTGCCTGTAATTATCAAGTGCTGTTCAGGTCCTAATTAATTGGTTCAGGTGTGTTTGATCAGGGTGAGAGCTGTGTTTTGCAGAAAGGTAGATCTCCAGGAACAGAATTGAGCAGCCCTGGTTTAAATCATCTGATTCAGTCACCTATGGAGGAGAAAATGACTAGGAATAATAAATGGCATGATTCAAATGAGCCAGTCAGAGAATGAATGTGCACAGCCACGCCTTTATTTTCAATAGTCTGTGTTTTGGTTAATCTACAGTGTCAAAGGT
Associated Phenotype:
Not determined