Busch Lab

ZMP

lig4

Ensembl ID:
ENSDARG00000060620
ZFIN ID:
ZDB-GENE-070820-10
Description:
DNA ligase 4 [Source:RefSeq peptide;Acc:NP_001096593]
Human Orthologue:
LIG4
Human Description:
ligase IV, DNA, ATP-dependent [Source:HGNC Symbol;Acc:6601]
Mouse Orthologue:
Lig4
Mouse Description:
ligase IV, DNA, ATP-dependent Gene [Source:MGI Symbol;Acc:MGI:1335098]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa38268 Nonsense Mutation detected in F1 DNA Not yet available
sa13669 Nonsense Available for shipment Available now
sa32694 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38268
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085648 Nonsense 762 909 2 2
Genomic Location (Zv9):
Chromosome 1 (position 28201366)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 28466793
GRCz11 1 29270724
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACATGATCCACATGTCACCTTCCACAAGGGAACACTTCGCTAAAGAGTA[T/A]GATCAGTATGGAGACAGTTATTACGTTGACACTAGTGAACAGCAGCTGAG
Long Flanking Sequence:
CATCAGTGCATGACCTTGGATGACCTGAACCAGTTTCGGTCTAAAGCTTCCGGAAAGCTGGCATCAAGACATCTAAACATCCATGAAGACCAGCCTGAAAAGAAGAAGCGCAAAATCGTCGCCAAGCCCAAGAAGACCATAGGAGTCATTGACCACTTTAAATCCCAGGATTTGTCAAAGGTTGCCAAAGAGACAGATATGTTTGAAGAGGTTGAGTTTTGTGTGATAAATGGCGATGATGAACATTCCAAAGCAGAGCTTGAAAAAGGGGTGGCGCGCTGTGGAGGCATCGTTGTGCAGAATCCTGGAAAGGACACGTACTGCGCCATTGCAGCTGTGCAGAACATGAGAGTGAAGAACCTCATCTCATCAGATCAGCATGATGTGGTGTGGGCTACTTGGCTTTTAGAGTGTCTGGAAAATAAGCAGGTTATCCCATGGCAACCACGTCACATGATCCACATGTCACCTTCCACAAGGGAACACTTCGCTAAAGAGTA[T/A]GATCAGTATGGAGACAGTTATTACGTTGACACTAGTGAACAGCAGCTGAGGGATGTCATTGAAAGGATCAGCTCCGCAGAAGTCAAGAGTCTGTCTGTGGCTCAGATAGAAGCAGAGAATGCTTGGGATGACTTGCCTACTAGCATTTTTAGGCCTTACAGTGCATACTTTGACCGGTGTGCTGACATAGGAGATCCCAAGTCTGTTATATGCGGTACGTGTTTAGACACTCGTGCCTTAGAATTCAGATTTCATGGCGGTAAAGTTGTGGAGAAACTCAAAGAAGGAATCTCACATGTGGTAGTAGAAGATATGAAAAGGGCTCTGGACCTAAAGACACTGAGGCGACTTCATGCCAAGAAGTTTAAAATTGTTCATGAATCATGGGTTACTGATTCCATCAAAGCAGGCCATGTAAAGGATGAGATTGACTACCTGATTTAAAAATAAAAGCTACTAGAAAATCAAAACACTGAAACATTTACACTTTTATACCTAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13669
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085648 Nonsense 764 909 2 2
Genomic Location (Zv9):
Chromosome 1 (position 28201370)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 28466797
GRCz11 1 29270728
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGATCCACATGTCACCTTCCACAAGGGAACACTTYGCTAAAGAGTATGAT[C/T]AGTATGGAGACAGTTATTACGTTGACACTAGTGAACAGCAGCTGAGGGAT
Long Flanking Sequence:
AGTGCATGACCTTGGATGACCTGAACCAGTTTCGGTCTAAAGCTTCCGGAAAGCTGGCATCAAGACATCTAAACATCCATGAAGACCAGCCTGAAAAGAAGAAGCGCAAAATCGTCGCCAAGCCCAAGAAGACCATAGGAGTCATTGACCACTTTAAATCCCAGGATTTGTCAAAGGTTGCCAAAGAGACAGATATGTTTGAAGAGGTTGAGTTTTGTGTGATAAATGGCGATGATGAACATTCCAAAGCAGAGCTTGAAAAAGGGGTGGCGCGCTGTGGAGGCATCGTTGTGCAGAATCCTGGAAAGGACACGTACTGCGCCATTGCAGCTGTGCAGAACATGAGAGTGAAGAACCTCATCTCATCAGATCAGCATGATGTGGTGTGGGCTACTTGGCTTTTAGAGTGTCTGGAAAATAAGCAGGTTATCCCATGGCAACCACGTCACATGATCCACATGTCACCTTCCACAAGGGAACACTTCGCTAAAGAGTATGAT[C/T]AGTATGGAGACAGTTATTACGTTGACACTAGTGAACAGCAGCTGAGGGATGTCATTGAAAGGATCAGCTCCGCAGAAGTCAAGAGTCTGTCTGTGGCTCAGATAGAAGCAGAGAATGCTTGGGATGACTTGCCTACTAGCATTTTTAGGCCTTACAGTGCATACTTTGACCGGTGTGCTGACATAGGAGATCCCAAGTCTGTTATATGCGGTACGTGTTTAGACACTCGTGCCTTAGAATTCAGATTTCATGGCGGTAAAGTTGTGGAGAAACTCAAAGAAGGAATCTCACATGTGGTAGTAGAAGATATGAAAAGGGCTCTGGACCTAAAGACACTGAGGCGACTTCATGCCAAGAAGTTTAAAATTGTTCATGAATCATGGGTTACTGATTCCATCAAAGCAGGCCATGTAAAGGATGAGATTGACTACCTGATTTAAAAATAAAAGCTACTAGAAAATCAAAACACTGAAACATTTACACTTTTATACCTAGGTGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32694
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085648 Nonsense 776 909 2 2
Genomic Location (Zv9):
Chromosome 1 (position 28201406)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 28466833
GRCz11 1 29270764
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTAAAGAGTATGATCAGTATGGAGACAGTTATTACGTTGACACTAGTGAA[C/T]AGCAGCTGAGGGATGTCATTGAAAGGATCAGCTCCGCAGAAGTCAAGAGT
Long Flanking Sequence:
CTAAAGCTTCCGGAAAGCTGGCATCAAGACATCTAAACATCCATGAAGACCAGCCTGAAAAGAAGAAGCGCAAAATCGTCGCCAAGCCCAAGAAGACCATAGGAGTCATTGACCACTTTAAATCCCAGGATTTGTCAAAGGTTGCCAAAGAGACAGATATGTTTGAAGAGGTTGAGTTTTGTGTGATAAATGGCGATGATGAACATTCCAAAGCAGAGCTTGAAAAAGGGGTGGCGCGCTGTGGAGGCATCGTTGTGCAGAATCCTGGAAAGGACACGTACTGCGCCATTGCAGCTGTGCAGAACATGAGAGTGAAGAACCTCATCTCATCAGATCAGCATGATGTGGTGTGGGCTACTTGGCTTTTAGAGTGTCTGGAAAATAAGCAGGTTATCCCATGGCAACCACGTCACATGATCCACATGTCACCTTCCACAAGGGAACACTTCGCTAAAGAGTATGATCAGTATGGAGACAGTTATTACGTTGACACTAGTGAA[C/T]AGCAGCTGAGGGATGTCATTGAAAGGATCAGCTCCGCAGAAGTCAAGAGTCTGTCTGTGGCTCAGATAGAAGCAGAGAATGCTTGGGATGACTTGCCTACTAGCATTTTTAGGCCTTACAGTGCATACTTTGACCGGTGTGCTGACATAGGAGATCCCAAGTCTGTTATATGCGGTACGTGTTTAGACACTCGTGCCTTAGAATTCAGATTTCATGGCGGTAAAGTTGTGGAGAAACTCAAAGAAGGAATCTCACATGTGGTAGTAGAAGATATGAAAAGGGCTCTGGACCTAAAGACACTGAGGCGACTTCATGCCAAGAAGTTTAAAATTGTTCATGAATCATGGGTTACTGATTCCATCAAAGCAGGCCATGTAAAGGATGAGATTGACTACCTGATTTAAAAATAAAAGCTACTAGAAAATCAAAACACTGAAACATTTACACTTTTATACCTAGGTGTCACATACTGTTCTTTTTGCTACATCTAGCGTAACAAT
Associated Phenotype:
Not determined