ZMP

appl2

Ensembl ID:

ENSDARG00000078139

ZFIN ID:

ZDB-GENE-081016-2

Description:

DCC-interacting protein 13-beta [Source:RefSeq peptide;Acc:NP_001121547]

Human Orthologue:

APPL2

Human Description:

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 [Source:HGNC

Mouse Orthologue:

Appl2

Mouse Description:

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 Gene [Source

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa44227	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa37994	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa44227

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000112853	Essential Splice Site	384	662	14	21

Genomic Location (Zv9):

Chromosome 25 (position 6034474)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	25	5670354
GRCz11	25	5796861

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTTAAGCGGAGAAGCATCAATCATTAGTATAAACTGTGCTGTTGATTTCA[G/T]GCTGTGGCGATCAAGCTCCATCAGACAGCTCTGCAGGCCGTGACTCCCAT

Long Flanking Sequence:

GGAGCCTCCAGATGGAAACTGTTGTTTTGTGTTTACCTTATGATTAAAGTTGTTGCATGTCCACTCTGAATGAGTGAGTTTTAGCTACTTGTACATTTAAGGAAGCATTCAGAAGAAACAAAACACCAGTGAAGAAACTCGACACAGAAGAACATGAAAACGGATGATCACTCAATGCAGAAGTATAAACCAGCCTTTAATCGCACCGCAATATACTTTGGGTTGATTGAATGCTTGATTCTGATTGGCTGATAAACATTCTGATGTGTGCAGTTATTTTCTTAATGTTCAATGGCTTGTCGTCAGTTCTCATTGTTCCTCATTTGTTTGTGTCTACAGTGGATTTGCACCCTGAACAACATTTCCAGACAGATTTATCTGACCGACAATCCTGAGGTATTAATAAATCTGTCTGTCGATCTTTAATCTAGTTAAGCTTTTAAATGTCACTTTAAGCGGAGAAGCATCAATCATTAGTATAAACTGTGCTGTTGATTTCA[G/T]GCTGTGGCGATCAAGCTCCATCAGACAGCTCTGCAGGCCGTGACTCCCATCACCAGCTTCGAGAAGAGAGCTGAAGGATCTCCAAACCCTGACAGGTAGATAACAACACCTCACGCACATCTCCATATACTCATCCCAATAATCACTTGATTAAGTCAGCGCTGTGTTTGGGGTAGAGCGAAGCCTGGTGGGCTCCCCGTGACCAGTCAAGAAGCTGAGAAATCCTCCGTCAGCCTGGAGCCTGAAGATCTGATTGTTCCAGGAACACCCATACAGTTCGACATCATGCTGCCCGCGTCTGAGTTCCTGGACCAGAACCGAGCCGGAGCCAGGTCACAATACACACAATACAGTGCTGTCAAAACAATCAGTGTTTACATATGTGTGTATATTTGATATAATATGATGTCACTTCGTCAACGAATAAAGATTCATTCGTTCACTTACTCATCCACACACAATCACTCATTCATTCACTTACTCATTCACTTTCTCAATTA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa37994

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000112853	Nonsense	606	662	20	21

Genomic Location (Zv9):

Chromosome 25 (position 6028715)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	25	5664595
GRCz11	25	5791102

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CTCACACTCTACCTCAGCTCAACTCCTGCTGTTTCTCCTCAGATCTGCTA[C/A]ACCATCAACCTGGCCAAGGAGATCGCAGACGCCCGGAAGGTAAAAACACA

Long Flanking Sequence:

TACAAATATAATTTTTTTTAAATTTAAAGATGTTAAAATAACATATTTTTATAACATATATTATATAAAATTAGCAACAAACTAGATTTGTTAATCTGTGTGTGTGTGTGTGTGTGTGTNTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGTGTGTGTGTGTGTCAGTTCCAGCTGCAGGATGTGAGTGAGTTCGCAGCTCATCAGGAGAACGAGCGTCTGATGGGGTTTGTGGTGAGGAGCTCAGCTGAAGATGACGAGCCCTCCTTCAGTGTGTTTGTGTTCGAGAGCAACACTGAAGGAGAGAAGGTGAAAAACACACCAGCACACACACACACACACACCTCACACTCTACCTCAGCTCAACTCCTGCTGTTTCTCCTCAGATCTGCTA[C/A]ACCATCAACCTGGCCAAGGAGATCGCAGACGCCCGGAAGGTAAAAACACACTCCAAACATCCTCATTCATCCAAACATCATTCCACCACAGAGGTGAAGGGTTAGTTCATTTAAAAAAAATGTAAATACCACAAGATTTGTAGATTTAATAACTTAAATTTTTTAGTTTTTATGCCCCAAAATGAATCCTGATGAACACAAAACGCACATTATTCAACATGTGTTACTGGAGGGAAAGTAGTGTTGTTCATTGTTATCAATATATTGAATAATCGTGTGTGTGTTTGACGTGTGTATCAGGATCCTGAAGCTCTGGCTCAGCTGATGAAGTCAATGCCACTCACCAATGACGGAAAGTTCCTGTTGCTGGACAACGAGACCGGAGACACCGCAGAAACAGCCGGACAAGAAGAGCAGGAGTCAGAGGCTTGATACACACACACACACACAGAACACACACTCATTCACACTCATTCACACACACACACACACACACACAC

Associated Phenotype:

Not determined