ZMP

si:dkey-108d10.2

Ensembl ID:

ENSDARG00000013310

ZFIN ID:

ZDB-GENE-091204-246

Human Orthologue:

MAP3K15

Human Description:

mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:31689]

Mouse Orthologue:

Map3k15

Mouse Description:

mitogen-activated protein kinase kinase kinase 15 Gene [Source:MGI Symbol;Acc:MGI:2448588]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa13317	Essential Splice Site	Available for shipment	Available now
sa37904	Nonsense	Available for shipment	Available now
sa24513	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa13317

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

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Mutation:

G > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000006615	Essential Splice Site	157	1331	3	29
ENSDART00000143099	Essential Splice Site	157	1321	3	29

Genomic Location (Zv9):

Chromosome 24 (position 26715453)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	25773810
GRCz11	24	25918851

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TCTCTCTTCTCTTTTCTCTTGCATAGGACATGGTGGCACAGAAAAACACA[G/T]TAAGTGWCAAAAGACTCCTTGCAGGACTGGTAATCCRATGAGGTTTGGYG

Long Flanking Sequence:

GATAAGTTATGTCTTCAAGCCTGCAGGCTCATATTCTCACATTTAGTATCTCTGTCATCTGAACAAAGAGGCCGCCCACCACTAGGCCCTGACCTACTATTCTGAGTCTAGGAAGGAGTTTATCTTTTCTGGGCACTGGACAGTAGAGCTGCCAGAACAACACGCACTGTTTTCAAGCAAAGGCATGCAGTCAGTCCCAGGACAGCTGCACATGGCCACGTTGCACACAGAGACATTGGAAGGCATGTGTTCTTCTGGCAAACTGTAACAATGACAATCACGCTTGGGGAGAAGCGTCACGCGATCCACTTGTGTATTTGTTAACATGTCCAACTGATTCATTCCCTATTAATAATGGAGTGAATGGCATTACACTGCAAGACGGTCTTGTGATTGATATTATCATGTGATATAAAAAAATACATGTTGCAATATTGCAGTTGAGTAATTTCTCTCTTCTCTTTTCTCTTGCATAGGACATGGTGGCACAGAAAAACACA[G/T]TAAGTGTCAAAAGACTCCTTGCAGGACTGGTAATCCAATGAGGTTTGGCGTCTGTTGTTGGTGTGCCAATAGCTTTGTGTATTAGACTATTTTTGAACATCTTATGATGACATACGTTTACATGCTCATGGCCCTAAAATAAACCCACCACTGTGAGCAGAAGCTGTATGCAAGAGTTGTATGAGCACAGAAGGTTCTAGTGTGTCACTTTGAAGACTGGTGCTGGTCCAGAAGAGTTCATAAGGGTTGTGAAGGTGTTGTGGTCATTTAAGTTAGTGGGTGTTAGTGGTTTTGATAAAAAGAGAGGGTCGTTGTGTGCTAGACTTTAAATAAATGTCTTATTGAGCAACTGGTGAAAAGAAGCTGACCTTGATGGTGATTTATAGCTGTGAAATGATCCAGTACACTTTTCAACATTTTGTGGATAGATGTGAATTTCTATGTTCGCTTTCACCTTCAACTATACTTTCTCAGCTGAAACGAGTAGTTCACTCAAACAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa37904

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000006615	Nonsense	199	1331	4	29
ENSDART00000143099	Nonsense	199	1321	4	29

Genomic Location (Zv9):

Chromosome 24 (position 26722075)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	25780432
GRCz11	24	25925473

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GGCCCAGCGCAGAGCATCAGAGTACATGCAGCCCAACTGGGACAACCTTT[T/A]AGGACCTCTGTGTGTCCCTTTGGTGGACCGCTTCGTCAGCCTTCTCAAAG

Long Flanking Sequence:

AAGTGAACGCACTTGATTGCACAAACAGCAGATCTGTGTGAAAAGGGGTGCACAGATGTACAAATCTACATTTGTTGACAAACAGTTTATTATTAATATTTACTTATCAGTATTATGGGAATTGTCGACCCGACAAATTTTATTGGACAAACATTTTTTAGTCTTACACCTTATCCAGAATATAAAAATACATTTAGATCATTTATTTTATTCATTATTATTGGAATGTGAAGAGACTTTCAACCAGCACAACTAAAAATGTTTCTAAAGACAATCACCTACTGCACCTTTAAGGCAACATGCTTTTTTGTTGTGTAGTTATTTTTACATTATCATGATATGAAATTGCATTTAAAACTGCTTTCTCCTTTTTTAGGCCTCTAGTGGGAACTACTATTTCATCCCATACCTGATGACACCCAACAACGAGTACTTGTGCTGTGAGAATGTGGCCCAGCGCAGAGCATCAGAGTACATGCAGCCCAACTGGGACAACCTTT[T/A]AGGACCTCTGTGTGTCCCTTTGGTGGACCGCTTCGTCAGCCTTCTCAAAGACATTCATGTCACGTCTTGGTATGACTGCTCATATTATGATCACCCCTGGCAGGATGCCAACTCCCATGCAGTGCTTCACAGATCCGTTACATGATGGTGTCATGTCATGTTTTGCTTAGCGTAAATCAAGCCAACACTACCTAATTTTAACCAAACAAATCATATAAAATACATTTTTATATAATGATTTCTTTTTTTGTTGTTAACATTGAATTACAGAGTTAAAATGGGATAGTTTACCCAAAAATGAAAATTCTGCCATCATTTACTCCCCCTTAAATGTGTTTCTTCTGTACAAAATGCTGATTGCTGGGACCCATGGACTTCCATTGTCCCTATTAAAGGAGTTGATGGTTGCCAGCAGCCAGCATTCTTCAAAATATCTTCTTTTTTTTCTTGAACAGATGAAAGAAACGCATAAAGGTTTAAAACCACAATAAATGATGAGG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa24513

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000006615	Essential Splice Site	314	1331	7	29
ENSDART00000143099	Essential Splice Site	314	1321	7	29

Genomic Location (Zv9):

Chromosome 24 (position 26725229)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	25783586
GRCz11	24	25928627

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GATCTCAGGAAAAAATGCATTTATATTTGTGTGTGTGTGTGTGCAAACTC[A/T]GACGAAACAGCCCTGGTGATCGAGAGCAGGCGCTGCGTGTGATGTTGCAG

Long Flanking Sequence:

ACAGTGCTTCATACAAAGATGCACTCCTGAATGACATCCGAAAAGCTCGAGATAAATACCAGGGTGAGGAGCTGGCCAAAGAGCTTTCCCGTATCAAACTCCGCATCGACAACACTGAGGTTTTGACTCAAGATATTGTCATGAACCTGCTTTTCTCCTACAGAGACATACAGGTATGGTGTAGAATAGACCAAAACATTTAAAATATCATTAATAGCTGTACTGCTGGTTTTAATGGGCTTTGGTGATGTGTTTTTTCAGGATTATGATGCTATGGTTAAACTGGTGCAGACCATTGAGATGTTGCCCACCTGTGACTTGGCCAACCAGCCCATGATTCAGTTCCACTATGCTTTTGCGCTCAATAGGTGACCACAAATCTGCATTGTGTGGTATATTTTTTCCTATTCATATGCTTGGCAAACAGACATTTATCTTATACGCTGATTTGATCTCAGGAAAAAATGCATTTATATTTGTGTGTGTGTGTGTGCAAACTC[A/T]GACGAAACAGCCCTGGTGATCGAGAGCAGGCGCTGCGTGTGATGTTGCAGGTTCTTCAATCGTGTGAACACCCTGCTCCTGACATGTTCTGCTTGTGTGGCCGCATATATAAAGACATCTTTCTAGACTCAGACTGTAAAGACACCAAAAACAGAGACAACGCCATCCAGTGGTGAGTGAGTTTAATGCACTGCTGGAAGCATACTGTTTTATGATGCTTAAAGGTCTTATAAGTAAATAAAAGAAGTCCCTTAGTTTGCTGAAAAGCAGTGACATGAAATTATGTAACTATCAAAAGCATTAAATGTATTTAAAACACACAGAACGTGAACAGTCACATTAAAGGGATAGTTTGAAAATTGAATTGCAAAAAAAATACAAATATTCTCTATTTACTTGAAATGTTTTTGAGATTTTTTTTTTCTGTTCAACACAAGATATTTTCAAGCAAGCTAAAAACTTGAAACCATTGACTTCCAAAGTTGGAAAAATAAATGCTA

Associated Phenotype:

Not determined