ZMP
si:dkey-246l21.2
Ensembl ID:
ZFIN ID:
Human Orthologue:
DLEC1
Human Description:
deleted in lung and esophageal cancer 1 [Source:HGNC Symbol;Acc:2899]
Mouse Orthologue:
Dlec1
Mouse Description:
deleted in lung and esophageal cancer 1 Gene [Source:MGI Symbol;Acc:MGI:2443671]
Alleles
There are 8 alleles of this gene:
Allele Name | Consequence | Status | Availability |
---|---|---|---|
sa15793 | Essential Splice Site | Available for shipment | Available now |
sa18315 | Nonsense | Available for shipment | Available now |
sa16256 | Essential Splice Site | Available for shipment | Available now |
sa24479 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa15793
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000109223 | Essential Splice Site | 130 | 1702 | 4 | 38 |
ENSDART00000143174 | Essential Splice Site | 130 | 1701 | 4 | 38 |
The following transcripts of ENSDARG00000075825 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 24 (position 20976042)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 24 | 20223171 |
GRCz11 | 24 | 20367590 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGGTTTGTAGTGCTATGACTAAAAACACAGYATTAATTATTTTTCCATA[G/A]WAAAATCAGYTTTYAAGTGGTGTRTGGACAGTGGACTTTTGAGGAGCAAY
Long Flanking Sequence:
TAGGGCCTCCAACTGTTCAAACTTTCTTACTCTAAAAATTTGGAATCATTATTGTCCTTGGCTCAAGATGATTAGATTGCACAATGCCATTTTCAATTTGCAGATAAATTTACAAAGTGAAAATGAAAAAAAAAAAGTTACTTTGAACCGTTGTTTTGTCTACTTAATTATTTTCAGTTTATCAGATTGTTATCATCTAAATTCTAATATTTCATGATTTCATTGTAGGTGCACAGTGAATACAACAGACGTATTCAGAATGCTGATATGCTAGAGACACACATCATACAGGCCCGTCTTCAGGCTGCTGCAAAAGAAGAGCATGATCGCAACAAAATCCTGGAAGAAGTCGGTGAGGCTTACCAACAGCTGGGACTTCCCCCAGGTAGACCTCTGTACTTCTGTTGTGTTAAAAACAAAGCAGTATTGTTATCATCCACAGTCTGTTGGCAGGTTTGTAGTGCTATGACTAAAAACACAGTATTAATTATTTTTCCATA[G/A]TAAAATCAGCTTTCAAGTGGTGTGTGGACAGTGGACTTTTGAGGAGCAACAGCTTGATTTGCCCACTGGACTACACAACAGTGCACAACCCAGTTGTTAAAAGCCCAAAAGGTAACATTTCACATAAATTTACACCTCTTCCACACACAATTGCTGTTTTTCTAATTGTGCACTTCCGATTTGAGGAAAGAAGGAGGAAATAATTTGAAATAAAAATGTTGTGTCTCAAGTAATCCATAAACACAGTGTAAAGTGAGAAAAAAGTATGTTTGGCTTTGTAATTTATTTTTATCCATGAAGAAAATGACATTTTGCTTGGTGTTTTAAAGTCAAAACAATATTTTGTTCCTCCAGATAATTTTTTTTATTGATTTCTATTCTGTACAGTAATATTCAACACGTGCATAATGTTGACTTGTTTCAAATTTGTAGTTATTCATGGTCTGCTTATTTTTCCTAATTCTAATAAATTAATTGGAGTACTTAATGGATGAATTGTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa18315
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000109223 | Nonsense | 325 | 1702 | 7 | 38 |
ENSDART00000143174 | Nonsense | 324 | 1701 | 7 | 38 |
The following transcripts of ENSDARG00000075825 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 24 (position 20970549)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 24 | 20217678 |
GRCz11 | 24 | 20362097 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGCGCCTATTTTCACTGCRAATCCACCAGTGATCTTCTTCAGTGACTAC[A/T]GAGTAGGACAAGTCTATGAGGTACAAAAGYAACTTATWTTGCATTCATTT
Long Flanking Sequence:
TTCTCTCATATTCGCCTTTGAAAACACTATTGGTTGGAATTAGGGAAGGGTTTAGAGTAGGTCAGTGTTTTGCTAGGTGATCTGCATGACAAGCCCTGCCTTCTCAAGGACATGTACAATAAAAAAGTGTATCTGAAACAAACAATAAAATGTACCCTAAGCAATGTATTTCAGGTTCTCAAATATGTAAACAGTGCACTCTACTGGATTTGTCATCTGAAATATGCAACGAAACACACCTGAAGCAATGTATTTTACATTTTGCAAAATGTCAATTTTGTAATTTATGTAATTTAAATAATGTAATTTATGTATTAAAGCGGGTATGTAAAAGTTCCTTGTTAGCGGTGACACTTTCGGCTGATGCACAAACAAATGGTTGCATTCTGGATATCTGACAAAATGTGGTGACAAAATGTTTTCTTTGTTTTATAAGAAGTCTTGAGGGTCATGCGCCTATTTTCACTGCAAATCCACCAGTGATCTTCTTCAGTGACTAC[A/T]GAGTAGGACAAGTCTATGAGGTACAAAAGCAACTTATATTGCATTCATTTTAATTCATTTGATTCACTTGATTCAAGCACATTTTCACTGTGCTATATCCTGTATACTGTATAGTAAGATTTGCTGAGTAAATAACTATTTTGTGTGTTCTATTTTTACTAAATGACCAGTAGTGTTGATTTTCCCTCCAGAGCCCCTTCTGAATGGTGTCTTTCCAGTGCGGTGTGTTTTTGGTTTTAATAGCGCCTTGTGTTCCCTGTAGACCTCAGTGGAGCTCAAAAACATGACTGCGAGCAGCCGTCACATTCGAATGATTCCTCCAACCTCCCCACACTTCTCTGTGGGTTTGGGTGAGAACCTGCTAACCTCATGAAAGACTCATTTATGTTGGCAGAAGGGGGATTTGAACCATTTCCATTGATGCTGTTATAGGCATTTATAGCAATACTGAAGCAAATAGCAATGATAAGAATACAACCAGAATTAATATTAGCAATTAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16256
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000109223 | Essential Splice Site | 1156 | 1702 | 27 | 38 |
ENSDART00000143174 | Essential Splice Site | 1155 | 1701 | 27 | 38 |
The following transcripts of ENSDARG00000075825 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 24 (position 20953538)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 24 | 20200667 |
GRCz11 | 24 | 20345086 |
KASP Assay ID:
2261-8640.1 (used for ordering genotyping assays)
KASP Sequence:
AGCCTTTCTCAAATCAGACWGTCAATTCTGGWCAWTTTCTTACTTTTTNC[A/G]GGTTGGAGATCTAAATCCWACTCACATTCAYATGAAGAYRTCTGTGAGGG
Long Flanking Sequence:
ATTTAAAAATCATTTGATATGCTAATTTGGTGTTCAATAGTTGTTTAATAAGATGTTTTTCCTGACTCTATGGCATTTTCTTTTAGAAGCAGTGCACCTTTCCACTCCATCCAGGCCAAAAAAATACAGCAAAAGGCATATGATGGTTCGTGCAACCCATTCTTTTGTGTTCTTCAGTATCACAGAAAGTGACACCAAAGTCAGAAATCCATTTACCTTCTTTATATTCTTTTTATACTTTTAGAGTTTGTAAGCCGTCTGCTTTCCCATGGAAGAGGTGCAACATTTTATGTAGAACCAAAAAGTGGGATGCTTGGCCCATTCGAGAGTCAAACCATCAACATCACTACTTTCACAAATATGTGGGGGGATTATCAGGACAACCTCATATGCAAAGTATGTCACATTAAATTTAATTATTAAATTCTAATGATTACATCATAAAAGTTTAGCCTTTCTCAAATCAGACTGTCAATTCTGGTCATTTTCTTACTTTTTTC[A/G]GGTTGGAGATCTAAATCCAACTCACATTCATATGAAGATGTCTGTGAGGGGCTGTCCAGTTTACTTTCAGATGATTGGACCACAGCCTGACAATCAGAATCAGGGTCCAGTTATTAGGTCAATGTTTTTAAAGGTTTTTAAAGGCTTTTAAAGGTTCATTCGCAAGATTTACCATTACACTTTTCCCCATTCAAAACTATATTTGAGTTTATTTAATTTTAGTCATGAAGGCTGCTTCAGTGTATGTGGATTCCAATTGGCCTCCAAAATGAGATGCCGATTCAAAGTGCAGATACCGAGTTACAAAATCCACAAATTTACAAATGTAAACATTAGCTGACTTATCATGTACACAATATTGGACTGCAATATCAATATCAGTCCTATTATTGTCCCTTAAAAGGATTTTGTTCATTGATTGACAGATTTGGAAGCCATGTTTCTGGAGGAGACACTGTGTCACGCTCTTTACGACTCATTAACACCAGTCCATATGGTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa24479
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000109223 | Nonsense | 1556 | 1702 | 35 | 38 |
ENSDART00000143174 | Nonsense | 1555 | 1701 | 35 | 38 |
The following transcripts of ENSDARG00000075825 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 24 (position 20945124)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 24 | 20192253 |
GRCz11 | 24 | 20336672 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCTGCTTCCCTTCTTTGCAGTGATGATGGAGGAAAAACTCTACAGTTT[C/T]AGGAGAACTTGACCATTCAGTACAGCAATAACAGCATACAGGTGCCTTTA
Long Flanking Sequence:
TTAGACCCTTTATTCATTAGTGGTCACCACAGCGGAATGAACCGCCAACTTATCCAGCATATGTTTTACACAGCGGATGCCTTTCCAGCCGCAACCAAGTACTGGGAAACATCCATACACTCTCATTCACACACATACACTTCGGCCAGTTTAGTTTATTCAATTCACCTGTACCGCATGTCTATGGACTGTAGGGGAAACCGGAGCACCTGGAGGAAACCCACGTGAATGTGGGGAGAACATGCAAACTCCACACAGAAATGCCAATTGACCCAGCGACCTTCTTGCTGTGAGGCGACAGTGCTAACCACTGAGCCACCGTGTTTCCTGTGATAATTATAATAATTATTTTTTTAATTATATTTTTTTCGAAGGTTAAGGTGGCTTTCCACAATTCCGCTTCACTCCTGGCCTGTGTAAATGGAGCATGTGAGGAGTCGGACAGTCAGCTCTCTGCTTCCCTTCTTTGCAGTGATGATGGAGGAAAAACTCTACAGTTT[C/T]AGGAGAACTTGACCATTCAGTACAGCAATAACAGCATACAGGTGCCTTTATTTTTCTCAAGTCTCGGAACAAAAAGCACTTTTTGAGGATCACAAAGTAGGCTTTAATCACAGCTGCAATTTCAAGACAATTTTCAACAGAAAACGTGTAATAATCAAATGTTTTGGTATTTTTTATTTTAAAAAGTGAGAGAAAGGAATACTGTAATTTGCCAAATGAGTCTAAATTAATCACAATAGATTTCTATTTAAAATAAATGTTCATTAGAAAAAACTATCACGTTTTTTGAGCAGAAATAAATTCCACTTTAAAGGGATAGTTCACCCAAAATTTTTTTTTTTTCACTATTCACTCATACTGAAGTAGTTTATAATCCTATGAGTTTCTTAATTTTGTTGAACAACAAAAGAAAATATTTTTTAAGAAAGTTGGAAACCTGTAACCATTGACTTCCATAGTATTTGTTTTTTCTACTATGGATATCAATGGTTACAGGTTTC
Associated Phenotype:
Not determined