ZMP
gad2
Ensembl ID:
ZFIN ID:
Description:
glutamate decarboxylase 2 [Source:RefSeq peptide;Acc:NP_001017708]
Human Orthologue:
GAD2
Human Description:
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) [Source:HGNC Symbol;Acc:4093]
Mouse Orthologue:
Gad2
Mouse Description:
glutamic acid decarboxylase 2 Gene [Source:MGI Symbol;Acc:MGI:95634]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa37819 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa30034 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa37819
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021609 | Nonsense | 135 | 583 | 4 | 16 |
| ENSDART00000114229 | Nonsense | 135 | 187 | 4 | 5 |
The following transcripts of ENSDARG00000015537 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 24 (position 6240543)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 6127835 |
| GRCz11 | 24 | 6157164 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATATAGTGGAATCATTTGACAGGTCTACGAAAGTGATTGATTTCCACTA[T/A]CCAAACGAACTGCTCCAAAGGAATAATTGGGAGCTTTCGGACGAACCCGA
Long Flanking Sequence:
TATTTATTCCAATCTGCCTTTTCCCGTTAAACTCGGTTTTAACAAATATTTTGGTTATACGTTTCTTAATTTTTTTAAATATTCGTATTCTTTTTAGGGCCAATTTCAATATATACAGTTTTATATTATTTATTGTATATTCATTCATTTTTAACGAAATTAAACAGAAAGCTATCCCTGTTGTATTTTTATTATTAATATATTTGAGGATATTATTTTAATAAAAAGAGAACATTTTCATTTTTATTACACGTATTTTTAACAACAAAAATTATCAGAGATGTTTCTTTTTTTCAAGGTTAAATGAAGACATTTCACTATTGAACTTCAGATTAAACCCCATTATTTTACGCATTCATGATATGTTTTTTTCCAGATCTGTTACCTGCACTGGACGGAGACGCGAAGACTATGAATTTTCTGCAGGAGGTTGTGGATATATTGCTGGCTTATATAGTGGAATCATTTGACAGGTCTACGAAAGTGATTGATTTCCACTA[T/A]CCAAACGAACTGCTCCAAAGGAATAATTGGGAGCTTTCGGACGAACCCGAGACTTTAGACGATATTCTGATCAGCTGTCGCGCTACGCTTAAATATGCCATAAAAACTGGTGAGTGTATCATTTTATTTATTATATACGCGACATATATAGATCAAATTCACGATGGGATGTATTGTATTAAATATGATATATTTGATCTGTATATTATCCAAAATATATATGTATGCTACTGATCGCATGGCTTGTAAAGCAGATCCGCAAGCGTGCGCGCGTGTGTGTATGTGTGTGTTTATGCCCGAAGGCGAATCGAATTAGATCAGAACATGACGTGATATTAAATGAACGCGTCCAGGGACGATTGTATTTTCTCTGGTGACATTTTAACTGCCATTATTTTGCAAAGCGATTTTCGTTTGGGGAATAATAATAATGAACGGTCAGAAAGACTGATTGATTTCCTGCTGTCCGCGCCGGTGTCTAAGATTTATGGTGTTTCTAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa30034
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021609 | Nonsense | 423 | 583 | 13 | 16 |
| ENSDART00000114229 | None | None | 187 | None | 5 |
The following transcripts of ENSDARG00000015537 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 24 (position 6230403)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 6117695 |
| GRCz11 | 24 | 6147024 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATCTGATCCAGGGACTGATGCAGAGCTGCAATCAGATGCAGGCCTGTTA[T/A]CTGTTCCAGCAGGACAAGCATTATGACCTGCAGTATGACACAGGAGACAA
Long Flanking Sequence:
CCTTGCAGTGCTCTGCTCTTCTGGTTCGAGAGGAGGTGAGACCGTCTGCTTCCTTCATCAAAACCAATGCATCACATACTATTCAAATATTAGTGCCACTTAGTTAGATCAAGTGACATTCGATAGAAGTCACATTTCTAAACTAATATTCCTGTGACGCAGAACTAATGAGTTATTTTTACTCTAAAATAGTCAATTTCATTTTTTGATTATGGTTAATTTATTTTATGATGTGTAACATAAGCCTTTATAGGTATAGTAAATGTTCATGTTAAATTGCTGTTCTCATTTAAAACAATAACAGCTTTAAATAGTCTTTTGGAGTATATTTAGTCTCAAAATATACTATGTGATTGATGACATTAATTGCCACATCATGTAATTAATAAAAATCGAATTCAATGAAAACTTTCAATTGCATATGCTTTTCTCCCCCCTTCCTCTTCTTGTTATCTGATCCAGGGACTGATGCAGAGCTGCAATCAGATGCAGGCCTGTTA[T/A]CTGTTCCAGCAGGACAAGCATTATGACCTGCAGTATGACACAGGAGACAAGGCCCTGCAGTGTGGACGTCATGTGGACATCTTTAAACTGTGGCTGATGTGGAGAGCTAAGGTATTATAAAACTGTATGTTTATGTGTTCCTTTATTGCTTTTGTTTATTAAATTATATATACATTGAATTTAATTAAATTATTTACATTAAATTATTTACATTATATCAAATTAAATAGGTTATTAGATCTATAGACTCTCGTTCTTAGATTGTTTTTGACAATTTGTGTCCTTCCCCCTCACAATTCTAGGTTTATATCTCACTTTTAAGAGTTTTTGTCTTTTTTTAAGGAATTCTGAGTTTACAATTTGCAATTCTAAGTTTCTATGTTGCAGTTAAAATAGTTTATAGAGTAGGCATTTAGAATTTTTTTTTATCCTCAGAATACTCTCAGAGTAAGTTTAATACTCTTGTTTTGAGTTTCCTTATTTTCTCTCCTCATTTTTTC
Associated Phenotype:
Not determined