ZMP
si:dkey-21o19.2
Ensembl ID:
ZFIN ID:
Human Orthologue:
PLEKHG3
Human Description:
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 [Source:HGNC Symbol;Ac
Mouse Orthologue:
Plekhg3
Mouse Description:
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 Gene [Source:MGI Symbo
Alleles
There are 6 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa25197 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa24324 | Nonsense | Available for shipment | Available now |
| sa14419 | Nonsense | Available for shipment | Available now |
| sa37696 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa37697 | Essential Splice Site | Available for shipment | Available now |
| sa15459 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa25197
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000128986 | Nonsense | 134 | 387 | 5 | 12 |
| ENSDART00000144478 | None | None | 159 | None | 5 |
Genomic Location (Zv9):
Chromosome 23 (position 24408734)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 24195300 |
| GRCz11 | 23 | 24121851 |
KASP Assay ID:
554-7589.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACATGTCTATGTATTATGATTTCTGTCTGCAGGCTATGAGCGAAAGATA[T/A]CTGGTTTTATTTTCCTTCCACTTGTTAATCCTTGCTTTGGACGGTTCCAA
Long Flanking Sequence:
CTGCACCTTGCACCACTGAATCAATGAATCGATTTTTTGTGGTTTAATTAACACACAATTCCACATCACATTGTACAGTCCTACTTTTGCTTCTTCTTTTTTTCCTAACATTTGCCAAATTCCACGTCATTCTGCCTTAAAAAGTAAACATTTACTGGATTCCTTGGAAATAATGTTTGTATTCTCATTTCACAGCTAGCGGTCTGGGGCTGGACGAAAGAAGAGCTTCATTATAGACTGTATACTCAGCCTATTAGAGAATGGGAAGGACGAGCACCACACACTTATGGAGACATTATCCACTCATCTTCTGTTTATTTACACAGTGGATACACAAAGGTAGCAAATCAACAAACCCGATTCATACTAGACAGTTCATTTGACAATCATACATTTTTACTACATATTTTGTTTCTATCCATTTTGCAGCCAAGTTTATTTTCTTTAATGGACATGTCTATGTATTATGATTTCTGTCTGCAGGCTATGAGCGAAAGATA[T/A]CTGGTTTTATTTTCCTTCCACTTGTTAATCCTTGCTTTGGACGGTTCCAATCGTGATTTTATATACGAGGTAAGACTCAATAGACTCCGTAAAATTCCATAGAAGAATCATTTTGGTAACACTTTATAATAACTTCACCGCCTTTATTAAGCATTAGCAAATAGTTCGTCATTGGTTAAGCTTTGACATTAATGTACTCAATGACTTTATTGTCATACATGTTAAGGTTTTCATTACTAAATTTTAATTGCATTACTTACAAACCACTTATTTAAGAGTATGATAATTTAATTTTTTGGTAAGATTGCAATTTTTTCCCCATTTCCTAAAGTTGTACAGTTTGAGTTTTGTATCTTAAAATTAATATGTTGTTAACACTTTAGTTTAGGTCACAATTTAAGGTATTAACAAACCATTAATGGACGCTTTCAATTGAGTGGGACGGTACGGTATGGTGCGTTACCACTGTTTAGTAAACTAGTATTACTAGTTTATTAAGG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa24324
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000128986 | Nonsense | 173 | 387 | 6 | 12 |
| ENSDART00000144478 | None | None | 159 | None | 5 |
Genomic Location (Zv9):
Chromosome 23 (position 24410069)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 24196635 |
| GRCz11 | 23 | 24123186 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAGGGTATTCTTCCTCTCTCAGCCATTGAAGTGCATCTGATCCCACAG[C/T]AGGACTCCAGTTCGCCACATATGTTTGAGATTAGTGGTAAGAGCCTCTCT
Long Flanking Sequence:
TAAAAATATGATGCATAAATGTTGACCTAATCATTTACTTGCTCATTCTGAATTATCCTCAAAGCCACCAACTACTTTTAAATAACTGTTTTTGTAAATAATAAAGGAAAATTGACTAACAATGTATAAAAATACAATCATTAAGCACATTATATATGTGCTTATAAGCCAAGAATACAGCTTTTGTGGCTGTATTTATAAACTGTTTGCTAATATTAATGTAGAGTTAATACTTAAGACAGGATGAACTGTTTGATAATGCTTAATAAAGAATTTGTAGTGTGCAGTTATTATAAAATGTAAAAAAATTTAATAGTTCTTCAAAGAGACATTTATTGGAAAAAAAAAACATTTCTGAAACTTTTGTGCACTCACTGGAAAGGTCATATGGAACCTTGTGTATATGAGCATTGGGAAATATCTGTGTCTAGAGTTATTTCTGTGTTTTGTCACAGGGTATTCTTCCTCTCTCAGCCATTGAAGTGCATCTGATCCCACAG[C/T]AGGACTCCAGTTCGCCACATATGTTTGAGATTAGTGGTAAGAGCCTCTCTGAGGGGAAGAAACTAAGCTTAAATCTCTAAACTGAACTTGAATATGACAACTTTGAAATCACAAAAACTATTTAATCATCATAAACCTGTATTTATGATGCACTATAGGACCCATGGTGGACTCGAAGATCTTCATTTGTGCTGGTGCTGCTGAAACAAAAGCCTGGATGGAGAACATTGAGGACAGGCGATACAAGTCTGTAAGACAACAGCTGAGCCCGTCTCATAGTGCTCTCTCATACCTGGTAATTACCGTAGCCTTAATTTACAAGTGCGAGATTAACTAATTTTGAATACATGATATAGAAAATGTAGTTAGCAAGATGCAACCAATATATTACCTATTATCATTGATTGCATTTTGATTACTTTTAGTCTATGACATTGATTTTAATAGGAAAATCTTGAGAAAAATAAGAAGAAAAAAAGTAACAAAACAAAATACAAAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa14419
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000128986 | Nonsense | 254 | 387 | 8 | 12 |
| ENSDART00000144478 | Nonsense | 26 | 159 | 1 | 5 |
Genomic Location (Zv9):
Chromosome 23 (position 24411642)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 24198208 |
| GRCz11 | 23 | 24124759 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAAAAGGAGGAGCTGAAAAGATACTTGCTGCGGTCTCCCATCATGCAATG[G/A]GAAGGAGTCCCCATTCAGCACATGGGACATCCAAGATACCTCTCACTGGT
Long Flanking Sequence:
GTGCTGTAACAAATAAAAGCATGTCTGAAAACATGGCCACCTTTTAATTATTAAGTAAAAATCAGTCTCTAAATGTCAACATTTTCGTTTTATATTTACCATAGATGCACTGTCAATAAATAGCCAAGCATTAGCCAAAAGTTGCAATTCCACAGCATTTCAGGTGGTCTCAATTTTCTTCCATAGCTGACATAACTGTAAAACATTACATAGCTGCTTTAAATTGTTAATTGGTAACCTAAAAACCTTCTGAGTCATTTAAACATAAATTACAATATAAACTGACTTCAAAACATTTTAATAAACATGCTAAACTTAGACATTTGTTTTCATTACTTACTGTTTTATGCAATGTTCTTTACTTAATGAAAAATGTGAAGCAGACTGATTTCATACCATTGCTCAGATGTTTTATTTTCACCACTCCAGGTGCCGTGTGATGAAAACTGGAAAAAGGAGGAGCTGAAAAGATACTTGCTGCGGTCTCCCATCATGCAATG[G/A]GAAGGAGTCCCCATTCAGCACATGGGACATCCAAGATACCTCTCACTGGTGCACATCAGCAACGTATATGCAAAGGTCAGCATACAGATGATAAAATACAGAGTGGTATCCATGTAATTCAGGATGGTACTAAATATACCTATTTTTAAACAACAGAGCCGGCATTTGCAGGGACCTCAGGAGCGTTTGCTTGTGCTCTTTCCAAGTGACCTGCTCATTCTGTCTCTCGATTGCCATCGCATACGTGTGAAATATGAGGTGAGCTCATTTTGCTGACTTAACAACAAACTCTGCAAGAACACTGCACTATCAGCAATCCTATATGTATGTGGTGAACCATATTTGATTGAAAAGATAACTTGGTAAAAAAAAAGTGCTGACAGTGCACTTTAAAACATTCAGTTTCTTTAAGAAACGACTGCATTTTAAGGCACTTTTATGAAAGACCTTCAGGCCAGAATCACTATCACTTGACCTCAGCTTAAAGGGGTGGTCCAGAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa37696
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000128986 | Essential Splice Site | 339 | 387 | 10 | 12 |
| ENSDART00000144478 | Essential Splice Site | 111 | 159 | 3 | 5 |
Genomic Location (Zv9):
Chromosome 23 (position 24413812)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 24200378 |
| GRCz11 | 23 | 24126929 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCATGGAAAGATCAGCACTGCCTGGCAGACTGGAGTTTGAACTAACAGG[T/G]ATGTATCAAGCTGTGAAACTAGTTACACGCACAAACTAAATGAATCATGT
Long Flanking Sequence:
ACGTCGACTAAAGTTGAAAACATGATATCGTACTGGACCACCCCTTTAAAGGGATAGTTCACCCAAAAATGAAAATTCTGTCATCATTTACTCACCCTTACCTCATTCGAAACCAATTTCTTTTTTTCAGTTGAACACAAAAGAAGATATTTAGAAAAATGCTGTTAGCTGACACCAATTTACTTACAAAAAAAAAATCCTTCTATGGAAGCAACCAGCATTATTCAAAATATCTTCCTTTCTGTTCAACAGAAGAGATACATTTATAAAAGTGTAAAACTAAATGAAGGAAAATAAATGAGGAGGTAATTAACATTTTTGGATGAACAATCCATTTAAATGATCCATTAAAACTGACAAATTTGAATAATTTTTAAAACCACACAATGTCACAGCACTGAGTTGCATTGTTTTATACCGAAGGGTCGTCTGCCACTAAAGAGCATTAAAGCCATGGAAAGATCAGCACTGCCTGGCAGACTGGAGTTTGAACTAACAGG[T/G]ATGTATCAAGCTGTGAAACTAGTTACACGCACAAACTAAATGAATCATGTAGTGTGTGTGTGTGGGTGGGTTGGTGGGCTAGGTGTTAAAGATAAACACATCAGATACAACTCAAAGTTTGAAATCAAAATTTGCAGTCATATGCGTCTTCTCATGAATTAACAGAAATTGGGGGGAAAAAAACAGGAGGAGGCTAATAATTCTGACTTCAACTGAATAAGAATATATGACTGAAATGATTAGTTATTTACTAAATTGTTAAAAAACAATTATTACTTGTACTTAGATTATGACTACGATTTAAACATATTATAGGCATTAAGAAATTAACATCACCTGTAAAAAATAAATCCATAAAATATACTGTAAGAAAATGGCAATTGTGGTTGCCAGTACTTTACCGTTAAAAACATGGTGCAAAACGTAAAAGTAGTTTTTCATTTTTACGGTAAACTACCGTATTTTATTAATTTATCGAGGTAATATGAAAACCCATAAAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa37697
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000128986 | Essential Splice Site | 339 | 387 | 11 | 12 |
| ENSDART00000144478 | Essential Splice Site | 111 | 159 | 4 | 5 |
Genomic Location (Zv9):
Chromosome 23 (position 24416399)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 24202965 |
| GRCz11 | 23 | 24129516 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCTTCATGTTTTATGCTGATTTATGCCGACGATGAGTGATGTATTTTCC[A/T]GGTGAACTGATGGAGCCTCTGCTTGTCTCCTGTATTTACCCTGAGGACTA
Long Flanking Sequence:
AGATCAGTCTTTTCATTATGACCGGCCATGTGAAGACAAGAAATACTCTTGCATAACATTAACCCATTAGGGTAGCTTTAACTTTACTGGGGTAGGATATAATCCTACAGTATATTGGATATTGAGGTAGGATATAGTGTAAGATCTTTCATAAACATTAAGAGTGCCATATTTGCATACATTGCTTGTTTTGCTGTTTTAAAATTCAGAAACTAAGTGATGTTAGTCATAAAACTTGTGAATCACCTTCAGAAAATAGCAACGGGATGATAAACTTACTAGCTTCTCAATGTTCCTCTTATCAGCTACATTCTGTTGTAACTGTTAAAGATGCAAGTCATTTAAAATGCCAGTACACTTTTAAGTTTTCAGGCTTTTTTGTATAAATGCTAAAAGTGACAGTTCATGCAGGTCACTTTCTCTGTGTTCTCTAAACTGCTGTACAGTACAATCTTCATGTTTTATGCTGATTTATGCCGACGATGAGTGATGTATTTTCC[A/T]GGTGAACTGATGGAGCCTCTGCTTGTCTCCTGTATTTACCCTGAGGACTATCAAAGCTGGATCTTCCAGTTACAACAGGCAAGACTGCAGTTTTTGGATTTCCTCGACACCGCTTTCAACTTAAAACAGAAAACCTTTAATGTATTTTGACCATTCATTCATTCATTCATTCATACAATAATGGCATTTTTAACGCTTAAATGATTATGAAAAGTACATCGAGTGTGCAATTTTTTACTAAGCTTTTTCTGTGGTGTTCATACAGTATCACTAAACCAAATATATTCATTTTAATGACATCTAATGTATCTAGTAGTCCAATAAATTGCACTCTATGAGTCTAGCTTGACTTTTATACAGATAATGCATATTTATATGATTATAGAAGCATATTTTTCAAGAAAAAATGTCTTGAACACTCATTGTTTGTAGATATGCTGCTTTTTGACCATTTACCTAATGTTTTCCTGCATCCCTGCTGAGCATGTTAAAACATTATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa15459
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000128986 | Nonsense | 363 | 387 | 11 | 12 |
| ENSDART00000144478 | Nonsense | 135 | 159 | 4 | 5 |
Genomic Location (Zv9):
Chromosome 23 (position 24416472)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 24203038 |
| GRCz11 | 23 | 24129589 |
KASP Assay ID:
2261-7719.1 (used for ordering genotyping assays)
KASP Sequence:
TTGTCTCCTGTATTTACCCTGAGGACTATCAAAGCYGGWTCTTCCAGTTA[C/T]AACAGGCAAGACTGCAGTKTTTGGATTTCCTCGACACCRCTTTCAACTTA
Long Flanking Sequence:
AGCTTTAACTTTACTGGGGTAGGATATAATCCTACAGTATATTGGATATTGAGGTAGGATATAGTGTAAGATCTTTCATAAACATTAAGAGTGCCATATTTGCATACATTGCTTGTTTTGCTGTTTTAAAATTCAGAAACTAAGTGATGTTAGTCATAAAACTTGTGAATCACCTTCAGAAAATAGCAACGGGATGATAAACTTACTAGCTTCTCAATGTTCCTCTTATCAGCTACATTCTGTTGTAACTGTTAAAGATGCAAGTCATTTAAAATGCCAGTACACTTTTAAGTTTTCAGGCTTTTTTGTATAAATGCTAAAAGTGACAGTTCATGCAGGTCACTTTCTCTGTGTTCTCTAAACTGCTGTACAGTACAATCTTCATGTTTTATGCTGATTTATGCCGACGATGAGTGATGTATTTTCCAGGTGAACTGATGGAGCCTCTGCTTGTCTCCTGTATTTACCCTGAGGACTATCAAAGCTGGATCTTCCAGTTA[C/T]AACAGGCAAGACTGCAGTTTTTGGATTTCCTCGACACCGCTTTCAACTTAAAACAGAAAACCTTTAATGTATTTTGACCATTCATTCATTCATTCATTCATACAATAATGGCATTTTTAACGCTTAAATGATTATGAAAAGTACATCGAGTGTGCAATTTTTTACTAAGCTTTTTCTGTGGTGTTCATACAGTATCACTAAACCAAATATATTCATTTTAATGACATCTAATGTATCTAGTAGTCCAATAAATTGCACTCTATGAGTCTAGCTTGACTTTTATACAGATAATGCATATTTATATGATTATAGAAGCATATTTTTCAAGAAAAAATGTCTTGAACACTCATTGTTTGTAGATATGCTGCTTTTTGACCATTTACCTAATGTTTTCCTGCATCCCTGCTGAGCATGTTAAAACATTATTGGCAGTCACATTTATATTTGTTTTAACTTATTCTTGCTTTTATTATAATAATTTTATTATTTAATATACTGAT
Associated Phenotype:
Not determined