Busch Lab

ZMP

osbpl1a

Ensembl ID:
ENSDARG00000011281
ZFIN ID:
ZDB-GENE-050208-657
Description:
oxysterol-binding protein-related protein 1 [Source:RefSeq peptide;Acc:NP_001038547]
Human Orthologue:
OSBPL1A
Human Description:
oxysterol binding protein-like 1A [Source:HGNC Symbol;Acc:16398]
Mouse Orthologue:
Osbpl1a
Mouse Description:
oxysterol binding protein-like 1A Gene [Source:MGI Symbol;Acc:MGI:1927551]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa25178 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa39365 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37474 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa25178
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090468 Essential Splice Site 133 967 5 28
ENSDART00000111318 Essential Splice Site 133 972 5 29
Genomic Location (Zv9):
Chromosome 22 (position 16548134)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 16299888
GRCz11 22 16326158
KASP Assay ID:
554-7338.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTCCTAAAGACATTACACAGAGTGCCGAGATTAAAAGCATGCTGGAGGG[T/C]AAGCTTGAACAACACAAAGAATGACAGTGCTGTGGAATCTACCTTTGTTG
Long Flanking Sequence:
TTAGTGTAAAAATACTTTTAGTAAAATACTCTTAATACTTTATACATACATACATACTTTGCACATTTATTATTAATATTATCATTATCATTATTATTATTATCATTATTATTATTATTATTTAAAAAAAAAAATTTATTGTTGTTGTACAAAATTAATTGCCGTAGTTTATTAATCAGTAATATTTTTCTCTTCTTAGAATCATAGTAGTCATTAAATAGTAATATAATATTCATAATGGGAATGACTTGTTTAACCTATATACCTAGAATGCTGAACATTTACTGAATGCTTAACATTAATTTGATGTTAAACACTGATTGGATGCTGAATCCTGAACACTGATTGGACTGAGAATACTAACTGAATGCTGATTGTGCTGTTTAGGAGGTTGTGATGTTGCTCCTTCAGCATGACGCTTGTGCTTCGGTTATCAATGGGATGGCGCAGATTCCTAAAGACATTACACAGAGTGCCGAGATTAAAAGCATGCTGGAGGG[T/C]AAGCTTGAACAACACAAAGAATGACAGTGCTGTGGAATCTACCTTTGTTGCTAAACTATTAAATGTAAACTTACTAGCTACTGAGAGGACAGAAGAGAGGAAACTGGAGGAGCAGCTGCTGGAAGCGGCGCGAGAAGGAGCCGTATCTACACTCACAAGACTGGTAACCTTACTAACTTTATTATGTGTAGTTTTTCAATTGCTATATTGCAAAATAATAGTGTTTGTATATATGTACACACACACACAAGCACATATCTATGCATGAACTTTTTTTTTGGGTGGATGGTTTCTGGGTTCAGAAAATCTTTTTAAGTTCAGAAAGTTGTGTTGACACACACCGGGAAAAAAAACTCTTCTCAAATATTGCACTTACAAAACAATTCTATGTTGTAATTTTTATTGTTGTTTGCAATAGTGCTACTGTGCTGCCATGCCAACGTGGGTAAAATGATGCAACTGTTTTATTGGCTTGTGTTTTTAAAAGAATAATAATAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39365
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090468 Essential Splice Site 247 967 9 28
ENSDART00000111318 Essential Splice Site 247 972 9 29
Genomic Location (Zv9):
Chromosome 22 (position 16550331)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 16302085
GRCz11 22 16328355
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGGGCATGACACGGCATGTTAAAATGTTTGAAGGGCCTCTTTGGAAGG[T/A]ATTTAAAGTGTTTATCTATAGTATGGCTATGTATTTGGCTATGTATTTTT
Long Flanking Sequence:
ATATACACTGTTAATACCTGCAATTGCTGTAATTGGATTTACTAAAATGCATTTTAATACTAGGTGTAAACAGAGCTATAGTGGAAAAGCTCCAGATGTTTTAGATTTTGTTTACATCTGTAATTACTATTTTTTGTGACTCATGAAAATCATGTGACTTTTGATTGGGTTGAAGCTGAGCTGAAGCTAATTCATGCACTTGTTGTTTTCAGATCAGACTGTTTTTGACTTGACTAACGATGCAGAAATGAAGCAGATCATTGCAGGAAATGTTGTGAAAGTAGGTTGATTAAGCTAGGGAGCTCTGTCTCAGTGTCACAAATGTATGTGATGCATGTTGTGCGCTTTTAAAACACCATTGTCCTTCTCATATCATACTAAAACATTCTTTGTTTTGCGAATTTGACTGCTTTTTTCAATGAATTTGTTTTTTTGTGATATTTGAATCCGGCAGGGCATGACACGGCATGTTAAAATGTTTGAAGGGCCTCTTTGGAAGG[T/A]ATTTAAAGTGTTTATCTATAGTATGGCTATGTATTTGGCTATGTATTTTTTATATTATTTTTTATTGTGTAAGTTTTTTTTTTATCTTCCAGAGTTCAAGGTTTTTTGGCTGGCGCTCCTACTGGGTGGTTCTTCAAGACGGGGTCTTGTCATGGTACCCTAAACAGTGCGTATTTTCCTTCAGTTGTATTTTGTAAAAACATCAAGATTATTATTTTATATTATTATTATATTTTTAAAATATTATTTAACAGACCATTGAAATTTTCACAGTATGTCTGATAATATTTTTTTTCTTCTGGAGAAACTCTTATTTGTTTTATTTTGGCTAGAATAAAATTAGTTTAAAATTTTTTTAAAGCCATTTTGAGATCATTTTCAAAATTATTAATCTATTTAAGCTATATATTTTTATTATAGTCTACAGAACAAATCATCGTTATACAACCTGCCTAGTTAGCTTAATTAACCCAGTTAAGCCTTTAAATGTCACTTTAAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37474
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090468 Essential Splice Site 653 967 21 28
ENSDART00000111318 Essential Splice Site 653 972 21 29
Genomic Location (Zv9):
Chromosome 22 (position 16564049)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 16315803
GRCz11 22 16342073
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCAGTCTGTTGTGCGGTTGAGAATATTCACCATGCCCCTCAACTTTGTA[G/T]GGATGATCTTGATTTCCGGCTGATATCTGAACAAGTGAGCCACCATCCTC
Long Flanking Sequence:
CGAGTTAGTCAGGTAAGAGATTGAATGTTCATTTGTTGGCTTTAATTTTACCACCTAAGGTGCAAATGTTACACATTTGCTGTTTTGAAAGTTAAAGCAGTAACATTATTATTAGCATATAGCATATATGGTTAGCATTAAAATTCCAAATAAAAAAAAAAAACATGAAAATGTTAGCAAAAATGCATTAAATTAGCGAATGTGCTAAATGTCACAAATACACTTAGCACATTTACAACACAAATACTATTGCTGACACATTACTAATGCTAACATTTTTACATGCATCAATTATATTGGCAGTTTTATTTAGTTTTTTCAAGTGTAAAAATGTTAACATTACTGTTAGCATTAGCAATACTGTTAGCCATTGTGTTCGTTGTAAATGTGCTATTGTTAAAACTTTGGTTATCATTAGTGTGACTTTTATTCACTTAGCAGTCCGAGTTTATCAGTCTGTTGTGCGGTTGAGAATATTCACCATGCCCCTCAACTTTGTA[G/T]GGATGATCTTGATTTCCGGCTGATATCTGAACAAGTGAGCCACCATCCTCCAATCAGCGCCTTCCATGCTGAGGGTTTGCAGAAGAACTTTGTGTTTCATGGCTCCATCTATCCCAAACTGAAGTTTTGGGGCAAGAGCGTGGAGGCTGAACCTAAGGGCATCATAACTCTTGAACTTCCCAAGTAAACATTTGTGCAATAATTTGTTTATTAATATCAATAGACACCTTTTTTCAATAGTAACTGTTTTTGTTGCTTATAATTGGTTTGGGTCTACTTTTTTGGTAAATTAGTAAATTTAGGAGCAGTTTTATTATGAATATATTTGGTAAATCATCAACATTTTGAAATGTTTATGCATTCTAAGCATATTCATGTTTTAATGTACCAAATTAATCCCGTTGCAGGCATAATGAGGCGTACACATGGACGAACCCCACGTGTTGTGTCCACAACATCATTGTGGGACAGCTGTGGATTGAACAGTACGGCAACGTTGA
Associated Phenotype:
Not determined