Busch Lab

ZMP

aox3

Ensembl ID:
ENSDARG00000071475
ZFIN ID:
ZDB-GENE-001205-2
Description:
Novel protein similar to vertebrate xanthine dehydrogenase (XDH) [Source:UniProtKB/TrEMBL;Acc:Q1LW04
Human Orthologue:
AOX1
Human Description:
aldehyde oxidase 1 [Source:HGNC Symbol;Acc:553]
Mouse Orthologues:
Aox1, Aox3, Aox3l1, Aox4
Mouse Descriptions:
aldehyde oxidase 1 Gene [Source:MGI Symbol;Acc:MGI:88035]
aldehyde oxidase 3 Gene [Source:MGI Symbol;Acc:MGI:1918974]
aldehyde oxidase 3-like 1 Gene [Source:MGI Symbol;Acc:MGI:3529596]
aldehyde oxidase 4 Gene [Source:MGI Symbol;Acc:MGI:1919122]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa37465 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa43795 Nonsense Mutation detected in F1 DNA Not yet available
sa39364 Nonsense Mutation detected in F1 DNA Not yet available
sa37464 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa574 Nonsense Available for shipment Available now
sa37463 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa18330 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa37465
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Essential Splice Site 62 1241 3 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14257185)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14088293
GRCz11 22 14113070
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCTGCACTGTGATGGTGTCCAGATATGACCCTCTCCAGGACACCGTGCT[G/A]TATCTTTCACCAATACATCAAACAAGCAGCATTAAAGCTTTAAATGAAAC
Long Flanking Sequence:
ATAAACCAATTCCTCCATTGTTTCATTACTATGTGCGCTTTTAAGTTGCGATAAGGTTTTAAAATTCTGTTAATTCTGTCATCACTTAATCACCCTGTGCTTGTATGATTGTTAAAGATAAGATCTATATTGAAATGTTAACTAAATGGTTAACAAAAGCCATTAACCTAAATGGCTAACATGCATAGTAACAAAAATTTGTCAGATTTTCTGTTTCATCCAAAGAAATTCTTACAGATTCTGTTTAAATTGGGAATGCATATTTTTTGTTGAATTGTTCCTTTAACTAACATATAACAATTTACATTTATAGTCTATTTGTAAGTGTGTGTAGTGTAATGTAATATGTGTAATTGTAGTAAATCATATCATTTCTATGCTTATGTGCTCTTTCTGTATTCAGTCGGTCTAACGGGCGCAAAATATGGCTGTGGTGGAGGGGGGTGTGGAGCCTGCACTGTGATGGTGTCCAGATATGACCCTCTCCAGGACACCGTGCT[G/A]TATCTTTCACCAATACATCAAACAAGCAGCATTAAAGCTTTAAATGAAACAAACTAATGAAAGACATGTTTTTTAACATAATTTATCTGAAAATAGTTTCAACATGAATCAACATAAAGTTATTATTTTGGGGTGGCACAGAGGCTCTAAAGTCATTAGTTTAAGCCCCACTAAATCTGGTTTCATCTATACATGTTTTTTCTATTTATTTACAGTTTGAGTTGAATTATTGGAACATTATGGGAACATCTCTGCTCTGTTGATTTTTGATGTTGAAAATTTGACTGTCCATTTTAACACTGTGACTTTATTGACGTTTAATACTCTCAGAAAAAAAGGTACAAAACCTGTAATTGAGGCAATACCTTTTCATAAGGTGCACTTTTTTACCATAAAAGTCCACATGTGTGCATTTTAAGGAAAATATTAATATATAAAAATAAATTAATAATAGTTTAATAATACTTAAATATTCCCAGGGATGGATAACATGCTGGATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43795
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Nonsense 220 1241 8 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14253529)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14084637
GRCz11 22 14109414
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAAGGTCAGGTGGATTTCACCATCAGATCTAAAAGATTTAATCAAGCTG[A/T]AAGCTGAACACTCTGACGCACCTCTGTTGGTTGGAAACACAACCATAGGT
Long Flanking Sequence:
TAGAGGACAAAAAGTTATCTATTTTGTTTCAGACTCCAGTTTGCTGCCAAAATGGTGGTGGCAATGGAAAATGTTGCATGGAAAACGGCAACTCTCACAACGAATCTGATGTAAGACAATATTAGCCACATATCCCTACAATTTCCAGCACATGAGCACTCATTAAAGTACAATTCATTATTTATTTAAAAAGACAGAGACTGGTTACTGTAGGTTATTAACTCTTCTACTACTTTGGTATCATTGGTAGATATCTGGAGAACTTTTCATCATGGATAATGTCTTACCCCTGGACCCAACTCAAGATCTGATCTTTCCACCAGAGTTACTGGTAAGTCATTTGGTAGCTTAGAAGAACACAGACTTCTCAGGCCACTAAGTTGTGCTATATCTCTACTTTCCATCAGATTATGGGAAAGAAAAAAGCAGAACGACATTGTTTCCAGGGTGAAAAGGTCAGGTGGATTTCACCATCAGATCTAAAAGATTTAATCAAGCTG[A/T]AAGCTGAACACTCTGACGCACCTCTGTTGGTTGGAAACACAACCATAGGTTGGTTTCAAGAGGAAGTTCATCCAACCATATACAGTATCAATCTCTACTAACCTTTTCTGTCCTCCTACAGGGCCAAAGATGAATCTGAACAAAACTGTCCATCCATTGGTGATCTATGGTGGAAGCATTGCAGAACTTCAAGCTATCAAATGGAGAAAAAATTGTAAATAATGTTACAACTATTATACAAAATCAACGAACATTGTGCCTAAAAGTAAATGAAACAATGTTGTTTTGTTCAGGCATAACTGTAGGGGCAGGATGCAGTTTGTCTGTTTTGAAGGATGTTCTTCAGCAAAGAATTGAGGATCTTGGACCAGAGAAGAGCAGGGTTTACCAGGCTCTCGTTCAGACACTGCAGTGTTTGGCCGGCAAACAGATTCGTAACATGGCTGTAAGTAACAAAAACAAGTGAGACATTTATAAAAACAGTAGTGCTGGAATATATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39364
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Nonsense 339 1241 11 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14252574)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14083682
GRCz11 22 14108459
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGATTTGTCTAAGTGAGGAGTTTTTCACAGACTTTGGAAAAACAGCTCTA[C/T]GACCTGAGGAGATTCTGCTGGCTATTGACATTCCTCATTCAAAGCCGGTA
Long Flanking Sequence:
AAAAACAAGTGAGACATTTATAAAAACAGTAGTGCTGGAATATATATGTGACCCTGGATCACAAAATCAGTCATATATGTGACCCTGGATCACAAAATCAGTCATAATAGTATTGTAACATTAAAGCTAAGGTAAGCTGTTTATTTCCTACAATGTGCTCCATGACGCTGGGGGTCGCACACTGTAAGTGAAATTTGTGCTATGATTACTTGTCTATTGTACTTGTTTATGTTACAATTTTGTTTATGTTGTAATTTCAAGACCATTGGTGGAAATATCCTGAGTGCCAACCCCAAGTATGACCTGAGCAGCATTTTAGCAGCAGCTGAGTGTACGCTACACATTGCTTCAAAAGGTAATAGCAGTTGAATTGGTTATAATTGTCAGCATATTAAACACATTTTAAAACTTTTGGGCTCCCTTTGTTCTTAAATACAGATGGTGATCGAGAGATTTGTCTAAGTGAGGAGTTTTTCACAGACTTTGGAAAAACAGCTCTA[C/T]GACCTGAGGAGATTCTGCTGGCTATTGACATTCCTCATTCAAAGCCGGTATGTTCTTGAAAATGGAGGACGCATAATAAAATAAATGCTAAAACTAAAGCCTTAGGCAAAATCTGACAGGTTTCCTCAAACATATTTCAAAGCTAGTAGTCTCATTACATCTATTATCATTTTGCCAATTTGAAAAGCTAACCCCTAGCAAACACCTGTGTTTTTCAGTGGGAGTTTGTGTCCGCATTTCGCCAGGCACAGCGCAGAGAGTTCGCTTTCTCCATAGTGAATGCTGGTATGAGAGTGGCATTCAGACATGATTCAAATGTGGTGGAGCATCTGGATATTTTTTATGGAGGCGTGGGTTGCACTCTGGTAAAAGCCAGACACACCTGTAAGGAACTGATTGGAAGGTACAGCCATCTTTACAAGGCCTATATGATTTATATTGAAACAAATGACAGAATAGACTCTTACCTTTTACTGAAGGTAATGGAAACATTGGTTATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37464
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Essential Splice Site 527 1241 14 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14250067)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14081175
GRCz11 22 14105952
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAACTGTTTGTTTCCATGGTAACCAGCACCCGGGCTCATGCAAAGATCAT[G/A]TAAGTTGAAAGATGTTCATTACAGATACATTTTTTTTTTCGCCCAACACA
Long Flanking Sequence:
GTTTCTTTTTCAAGTTTTACATGCAAGTGTTGCTGGAGCTTCAACAAAGGGTACAATGATTTTGTAATATTATTTAAAAATCTATATAGTTTAGATTATTGCTGACAAAATAGGTTTTTTGTGTGTTTCCCTTGTTGCTGAAGGAGGTTGGCGTGAATGATCTCCCATTAGAGTATCTCAGCGCATTAAAACCCTTCAAAAATGAAGTGCCGCAAGGAAATTACTCTTACCAAGTAAGCACAACTAAATAATATTGAAACCTCCTTAAAAATGTGTGTTATATTATGTTTAGTTAACCACAAAAATGTCTCCTTATCATTGAAATTGCAGCTTGTACCAGAGACTCAGTCCTCTAGTGACCCAGTAGGACGTCCCAACGTACACCTGGCAGCGCTCCAGCAGGCTACAGGAGAAGCTGTGTATTATGATGACATCCCATCTGTTAAAGGAGAACTGTTTGTTTCCATGGTAACCAGCACCCGGGCTCATGCAAAGATCAT[G/A]TAAGTTGAAAGATGTTCATTACAGATACATTTTTTTTTTCGCCCAACACAATCACACATTCCGGAAACTGAACACCATTGCAGGACATACAATCAGCTCATTCCATTATTCATAAACAGACACATGAACGGTATTAAGTTATGGGGTCAGACTTCTCTTCCAGCACCCATACATCTTGTTGATCCTGAGGATGTCATTTTTGGATTGTCCTAGTCTTTGTCAGACTGGCACAGTTTCATCAGAAATTGGAGTGATGGTTTCCAGACCATGCTGGATGGTGAAGGCTATTCTTAAAGAGTGATTGACAGAGTCATAGTTTTATGTAGTGATTTGGTTGTTAGTGTTTTGTTTCTGAAAGTTGTAGGCCCACCAGCAGGAATGGTTTTCCAGTTGATCCCGATGTACTGGTCGCAATCACTTCTAGACTGCTCAAAGTAGAAGCCCAGAGCATTAAAATAAATTATTTGTGGTGATATAATAATATTTTCTTTATGTCGCCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa574
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Nonsense 670 1241 18 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14236357)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14067465
GRCz11 22 14092242
KASP Assay ID:
554-0484.1 (used for ordering genotyping assays)
KASP Sequence:
TCTACATGGAAACTCAGGGAGTGATTGCAATTCCTACAGGAGAAGCAAGT[G/T]AAATTGAGCTATATGTTGCCAGTCAGCATGCAGCTTACACTCAGGTTTGT
Long Flanking Sequence:
TCATTTCAGGTCATTTGTGTGGGGCAGATTATTGGTGCGATTGTAGCTGAGACTAGAGAACAAGCTAAACGAGCAGCTCAGCAAGTAGACATTACTTACCAGGATATGCAACCTGTCTTTTTCACAATTGAGGTATTTCAATGCATAAGTATATCCATAAAACACTTCATAATGGGGAAATAAATGTTTATCACACACATCTAATCATACTAATCAAAAAAATTTTTTTTTTAATTCTAGGAGGCTATTGAACACGAGTCATTTTTTGACCCCAAGAGAAAGCTGGAAAGAGGAAATGTGGAAGAAGGTTTTGCAAAGGCAGACCAAATTCTAGAGGGTTTGTGTAAACCTGATTCGAAGTCCTTTTAAAACTGTGCTTTGACTTTTAGCTCAACTGTGCATAATCGTATTATATCACAGGTGAGATGTATATGGGTGGCCAGGAACACTTCTACATGGAAACTCAGGGAGTGATTGCAATTCCTACAGGAGAAGCAAGT[G/T]AAATTGAGCTATATGTTGCCAGTCAGCATGCAGCTTACACTCAGGTTTGTATTATGATTCACTATAAATATATTAATGTTTTAGATAATATGAATATTTAAGGAGAATCCTATAAAAAACAACAACAGAATTTACAATCTTCGGGCTAATTTTCTTTTAAAACAGGAAGTGGTGGGAATCACTCTCGGCATTGACTCCAACAAGATCACGTGTCATGTAAAGAGGCTGGGAGGTGGTTTTGGTGGTAAAGTCATGAAGATTGCATCATTATCTGCTATCGCTGCTACGGCTGCCATAAAGTAAATCAAACTAAGACCCTTACCTTTTTTACAGAATCGTTTCATTTCATTCTATTGAGCATTCACTTGTATTGCTTATATCATGCATTGTTGGGAAGAAAAGTTTTCTATGGCTTATAAAAATATGAAATGTTCAATGCTAATGCTATTTATTGACTGTATATTAAAAATTTAACCACAGGACTGGCCATGCTGTGCGAT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa37463
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Essential Splice Site 729 1241 19 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14236057)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14067165
GRCz11 22 14091942
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCATGAAGATTGCATCATTATCTGCTATCGCTGCTACGGCTGCCATAAA[G/A]TAAATCAAACTAAGACCCTTACCTTTTTTACAGAATCGTTTCATTTCATT
Long Flanking Sequence:
GAAGAAGGTTTTGCAAAGGCAGACCAAATTCTAGAGGGTTTGTGTAAACCTGATTCGAAGTCCTTTTAAAACTGTGCTTTGACTTTTAGCTCAACTGTGCATAATCGTATTATATCACAGGTGAGATGTATATGGGTGGCCAGGAACACTTCTACATGGAAACTCAGGGAGTGATTGCAATTCCTACAGGAGAAGCAAGTGAAATTGAGCTATATGTTGCCAGTCAGCATGCAGCTTACACTCAGGTTTGTATTATGATTCACTATAAATATATTAATGTTTTAGATAATATGAATATTTAAGGAGAATCCTATAAAAAACAACAACAGAATTTACAATCTTCGGGCTAATTTTCTTTTAAAACAGGAAGTGGTGGGAATCACTCTCGGCATTGACTCCAACAAGATCACGTGTCATGTAAAGAGGCTGGGAGGTGGTTTTGGTGGTAAAGTCATGAAGATTGCATCATTATCTGCTATCGCTGCTACGGCTGCCATAAA[G/A]TAAATCAAACTAAGACCCTTACCTTTTTTACAGAATCGTTTCATTTCATTCTATTGAGCATTCACTTGTATTGCTTATATCATGCATTGTTGGGAAGAAAAGTTTTCTATGGCTTATAAAAATATGAAATGTTCAATGCTAATGCTATTTATTGACTGTATATTAAAAATTTAACCACAGGACTGGCCATGCTGTGCGATGTGTACTAGAACGTGGAGATGACATGCTCATCACCAGTGGAAGATCTCCTTTCTTGGGGAGGTACAAGGTAATGAGATGTTATGAGTGATATTTGTGATTGAACAGCTGTGCTGCATCACAACGGTATAATTCCTGCCTTTTTCCTACAGATTGGCTATATGAATGACGGAACAATCCTGGCTGCTGATATCACATACTACAGTAATGGAGGATGCACTCTTGATGAATCCTCTTTTGTATGTTGGTTTTTAAGAAATTTAACATGTATAAATTGGTAATAGCTGATGAAATGTTGATAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18330
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Essential Splice Site 758 1241 20 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14235788)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14066896
GRCz11 22 14091673
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGACATGCTCATCACCAGTGGAAGATCTCCTTTCTTGGGGARGTACAAG[G/A]TAATGAGATGTTATGAGTGATATYTGTGATTGAACAGCTGTGCTGCATCA
Long Flanking Sequence:
TATATTAATGTTTTAGATAATATGAATATTTAAGGAGAATCCTATAAAAAACAACAACAGAATTTACAATCTTCGGGCTAATTTTCTTTTAAAACAGGAAGTGGTGGGAATCACTCTCGGCATTGACTCCAACAAGATCACGTGTCATGTAAAGAGGCTGGGAGGTGGTTTTGGTGGTAAAGTCATGAAGATTGCATCATTATCTGCTATCGCTGCTACGGCTGCCATAAAGTAAATCAAACTAAGACCCTTACCTTTTTTACAGAATCGTTTCATTTCATTCTATTGAGCATTCACTTGTATTGCTTATATCATGCATTGTTGGGAAGAAAAGTTTTCTATGGCTTATAAAAATATGAAATGTTCAATGCTAATGCTATTTATTGACTGTATATTAAAAATTTAACCACAGGACTGGCCATGCTGTGCGATGTGTACTAGAACGTGGAGATGACATGCTCATCACCAGTGGAAGATCTCCTTTCTTGGGGAGGTACAAG[G/A]TAATGAGATGTTATGAGTGATATTTGTGATTGAACAGCTGTGCTGCATCACAACGGTATAATTCCTGCCTTTTTCCTACAGATTGGCTATATGAATGACGGAACAATCCTGGCTGCTGATATCACATACTACAGTAATGGAGGATGCACTCTTGATGAATCCTCTTTTGTATGTTGGTTTTTAAGAAATTTAACATGTATAAATTGGTAATAGCTGATGAAATGTTGATACAAGTTAACATGTATCAAAGTACATGTAATTCCCAAGTAGATCAGTCTCCAAATCACAAACGGTGTATTTATATGTAATTTATGACCAGATTATGGAGAAAGCTCTTCTTCACATGGATAATGGCTACAAGATCCCTAATCTACGTGGACGTGGACTGGTGTGCAAGACCTTCTTACCTTCATACACAGCCTTCCGTGGATTTGGTGGACCTCAAGGGTTGACCATTATTGAGAGTGTGCTACATGAGGTGGCGGTCAAGTGTGGCCTAC
Associated Phenotype:
Not determined