ZMP
si:dkey-261o10.2
Ensembl ID:
ZFIN IDs:
Human Orthologue:
DENND1A
Human Description:
DENN/MADD domain containing 1A [Source:HGNC Symbol;Acc:29324]
Mouse Orthologue:
Dennd1a
Mouse Description:
DENN/MADD domain containing 1A Gene [Source:MGI Symbol;Acc:MGI:2442794]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa37235 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa16575 | Essential Splice Site | Available for shipment | Available now |
| sa14051 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa37235
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000055336 | Essential Splice Site | 42 | 1007 | 3 | 25 |
| ENSDART00000143151 | Essential Splice Site | 42 | 511 | 3 | 20 |
Genomic Location (Zv9):
Chromosome 21 (position 7938694)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 8346245 |
| GRCz11 | 21 | 8438784 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCAGGACTAGAGGTGCGCAGAAGTTTCCCCGACACATACACTGAACAGG[T/G]TTGTGCTTCTTAATTTTTTTTCCTCTGTGTTTCTCCAGGGATGTTGAGGT
Long Flanking Sequence:
CAGAAGCCCTGAGTTTTGATATCTTAAAGAGCGAGTTGGATTGTAGAAAGACAGAAGGTTGGTTAGATAAACAGGAGCTAGATTATTTAAAGCTTTATATGAAACAAGCAATATTTTAAATTCAATACGAAATTTAACAGGCAGCCAGTGTAAGGAGGATAAAATTAGGGTGATATGATCATATTTTCCAAACCTGGTAAGAACTCTGGATTTTGCATTTGCATTTTGTACTAGCCGAGGTTTGTTAATAGAGGATACTGGGCAGCCAGCAAACAGCATTACAGTAATCCAGCCTAGAAGTCATAAAAGCATAGACTAGCTTTATCATTATCATAATTTTATTTGTTAACATTCCCCAGATTTTTTGTACTTGCTAGGTAAATTGTGATGATATAGAAAAACACCTGTGTGTATGCATCTATTTAATAACTTTCAGATTTCTGTATTATTTTCAGGACTAGAGGTGCGCAGAAGTTTCCCCGACACATACACTGAACAGG[T/G]TTGTGCTTCTTAATTTTTTTTCCTCTGTGTTTCTCCAGGGATGTTGAGGTAGATCTCATAATTGTTGCTCACCTCAGTGATAATGCATTGAGCACCTGCTCTGACAGATGGAGTTTAAACCACTAGAGAGTCTGCGGTACCAAACACCCTCTGAAGGGGATTTAACCAAACTCACTCAAGATTGTGACTCAGGCTTACATATGCTTTCGCTGCGTCTGACTTCTGCTTATTCCCTCTTCTGTGAATGACACTATATCTAAAGTAGTCAGCAAAATCATATGCTGATGTAAATATTGTCTGCCAAAGAGCTCTGAAGGTGATGAGTGACTAGCAACTGTTTTCTCTTTTATTTATTGATATACATTTGAATTCATGCTAATCAGTGTTTCTGCACAGATAGGAGAACTCGTCCCAAAAAGAAGTAATAAAGGCTGCAATAACAATCACTTATCTACCTAAATATTTGTAATACAGTGGTCCCTTGTTTATCGCGGGAGTTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16575
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000055336 | Essential Splice Site | 488 | 1007 | 19 | 25 |
| ENSDART00000143151 | Essential Splice Site | 488 | 511 | 19 | 20 |
Genomic Location (Zv9):
Chromosome 21 (position 7956056)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 8363607 |
| GRCz11 | 21 | 8456146 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACTCCCTCACCTGGGACCAGAGGCGGCCAATCACAGTTCACTTTGGGCAG[G/A]TGGGTAAAAGAGATGTTGTGAATTCTTGTTAGATTRAAAAAGYGTATTGT
Long Flanking Sequence:
TCATGGCTTGAATTGTAATTTAATTAAATTTTTATTTTAAATAAAATTTTTATATTTTTATATATTTTTGTATTTTAAATAATAATTTTTAACTTTGATTTTCAAATCTTTTTAGTTATTTTATGTAATTGTATATTTTTATTTATTAGTTTGAGCGAATTTTGTTTTATCAGTGTGAGTAAACAGCAACAATTTCAAAAGATTTAAATGTGCAGTTTATAAGCAAATCTCTCATCCTCTGCAGGCCAAAGACCATGCCAAGATGGGCATCAAAGAAGTCAAGAGTCGACTCAAACAAAAGGTACTCATTTCAGTAAATAAATCAATTATTTATAAGTACTGCATAAACACACACCCATTCACTGTCACTGAATCTCTTGCAGGAGCTTACAGAGAACGGCTACTCAGAAGAGCCCGGGCCCACTCAGCTTCCCTCCACACAGAGCAAAGACTCCCTCACCTGGGACCAGAGGCGGCCAATCACAGTTCACTTTGGGCAG[G/A]TGGGTAAAAGAGATGTTGTGAATTCTTGTTAGATTGAAAAAGTGTATTGTGATGATAAACATGCAGTCTTGTTTAATTTATTATTTTTTTTCTTTATTCTTTAATGCGATCCACTCTATAAAGTGTAAAAAGATAAATCTTAGGCAATTTGACTGGAGTGCTGTTTAACCTAGATTTTTCTTAAATGCCGTTTTCTCAACTCTGCAATATTAGTTGCATGTTTATTTTGTTATTGAGAGGAAAAACTGCTGCACATATTGACTAGGATGATCATACCTGCCAGTTGTACTGGACACTTCCTGACCAGGATTCATTTATATTACTTTGCTCTCCAAGATTCATGCTTAAAGGTAATTATTGAATAGTAGTTTGACCAATGACTTTCAGGCATTGTACTTATTCAAGCAATCATGGCGCTTGGAATGTGGGATCTAAACAGAATGTTCAAAGTAATGCAAATATGCATTTATACAGTAATTAGATGTGTTTGTTTGAAGAGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa14051
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000055336 | Nonsense | 833 | 1007 | 24 | 25 |
| ENSDART00000143151 | None | None | 511 | None | 20 |
Genomic Location (Zv9):
Chromosome 21 (position 7969790)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 8377341 |
| GRCz11 | 21 | 8469880 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAAGACCAATGAGCCAAAYGAGGGACAGGAGCAGGACTTACTTAGCTTGT[T/A]GGATCCGTTGTGTGGAGCAACAAAGGATGAGGCCACMYCATCCCTTTCTA
Long Flanking Sequence:
TCTATCCTAAAAACTGTTTCAATTGTTTGTTCTCCAGCGGATGGAACTAAATGCTGGTGAGCGCACACGCACACTTCCCGTGCTTAAAACCACCAACCCATACAGCAAGCTCTGGAGTCAAAGGGAAGACCCATCCACCTTGCTTGGCCGGGAGTCACCATCCTGGGAGAGACCTCTTTCCGTTCCACCCTTAGAACCTTCTGATGTGCGCCCACCCAGCAAGGAGAGTTCAAATTCCTGTGCAGAGAAGACGGAAGGGGCTTGCATTACAATCCCTCGTCCCCAAGGTCGGAAAACACCAGAACCAGGTGCAGTGCTGGCTCCAGCGGTGACCCTGCTGCGCGGGGTTAGGCAGGCCTGTGACAAGGAAGGAGGAGTGTCTGCTGGAGGGCAGGAGTTTCGGCAGGCATTAAATATGTCTCCTCAAGCACAAACTCAGGTGGACCTGTTGAAGACCAATGAGCCAAACGAGGGACAGGAGCAGGACTTACTTAGCTTGT[T/A]GGATCCGTTGTGTGGAGCAACAAAGGATGAGGCCACACCATCCCTTTCTAAACCTCCTGTACCTCCTAGACCGAACCCCCCAAACCTTGCCAACTTTCCCCCTCCAGTGTCTATGAACCCTTTTACCCAACCACCGCAGTACCCACCTCAAAGGCACTATAGTCCTGTCGTCCCAGGTAACCCTTTCACCCCAGCCTTCATGAATCCCCCAGGTGCCAACTACTTCCCCGCCTCAGGCAGTCCATACGCAGTATTTAATCAGGCATCCACTGTGGGTGTGACCCCAACTGGAGGGGCGTGGCCCATTGGACGTGTTCTTCCAACCTCCAGCAGTAGTGGATCTCTTTCAACCCTCTTAGACTCATCTTCTCCGGCTACTTTGTCACAGCCTGTGCAAGTCTCCACAGATGCACCCAGTGACCCATTCAGTGACCTTCTTACCATGGCAACTACACCAACAATAATGGCCACGCCCCCCAAAAAGAAGGTGGAGGACTTGC
Associated Phenotype:
Not determined