Busch Lab

ZMP

cad

Ensembl ID:
ENSDARG00000041895
ZFIN ID:
ZDB-GENE-021030-4
Description:
CAD protein [Source:RefSeq peptide;Acc:NP_001009884]
Human Orthologue:
CAD
Human Description:
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [Source:HGNC Symbol
Mouse Orthologue:
Cad
Mouse Description:
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Gene [Source:MGI Sy

Alleles

There are 9 alleles of this gene:

Allele Name Consequence Status Availability
sa11882 Essential Splice Site Available for shipment Available now
sa37122 Nonsense Mutation detected in F1 DNA Not yet available
sa23778 Nonsense Available for shipment Available now
sa37121 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa9368 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa11882
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061361 Essential Splice Site None 513 None 44
ENSDART00000061365 Essential Splice Site 165 2230 None 43
ENSDART00000075262 Essential Splice Site 169 2154 None 41
ENSDART00000122056 Essential Splice Site 165 261 None 9
ENSDART00000125333 None None 485 None 11
Genomic Location (Zv9):
Chromosome 20 (position 38847528)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 38919940
GRCz11 20 38822819
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTTTGACAATCCAGAYGCCCGAAACCTTGTTAAAGAAGTTTCYATGAAAG[T/A]AGGTGTCTAGCTTCAGTGTTTTTTAGATGGATGATGTTGTGTAATGCAGT
Long Flanking Sequence:
AAATATATCTAGTAAAATATTATTTACTGTGGTCATGGCAAAGATAAAATAAATCAGTTCTTAGAAATGAGTTATTAAAACTAATTTGCTTAAAAATGTGTTGAAAAAAATCTTATTTCCTCTAAACAGAAATTGGGGGGAAAATATGCAGGGGGGCTAATAATTAAGGAGGGCTAATAATTCTGACTGCAACTGTATCTGCTATCCGATAAATCTTGTATAGCAATAAACAAACAGCACTACTACTCTTGCTTGACAAATATTTGCTTTTATTCATACAAAGTAAAAGCAAGAATTTTAATCCCATTGTACTATGGTTCAAAAAACTAAAACATAATTTATCCTGTGAAAATCAGGTGTTGACACTCGATGCTTGACCAAAAAGATCAGAGAGAAGGGAACCATGTTGGGAAAACTTGTGGTGGAAGGAACTCCAGCCGACAATATTCCGTTTGACAATCCAGATGCCCGAAACCTTGTTAAAGAAGTTTCCATGAAAG[T/A]AGGTGTCTAGCTTCAGTGTTTTTTAGATGGATGATGTTGTGTAATGCAGTGAAATTTATTTTTTGTGTTCTGTATTGCCCATTCAACAGGCACCAAAAGTGTTTAATCCAGAGGGCACAGTGAGAATCACTGCTATAGACTGTGGCATCAAGTACAACCAGATACGTTGCTTGTGCCAGAGAGGCGCCCGGGTCACTGTTGTCCCCTGGGATCAACCTCTGGACAGCAATGGTAAACAATAACACTATTGTTGAGGGTTGTCTTCTGGGAAAATGGCAAATGAAATGAATGTATAAACAACTGGTGTATTGTGTGTAAACTTTGTGAATCCCCAAAAATGATTACATAAATTGATAAGTAATAATTTGTATCAATATTTCACTCCCCTAGTAAATGCATATTGAAAATGTTATCACTGGGCATGTTGCCTCTGTTTTTTCTAGACTTTGATGGGTTGTTTATCAGCAACGGTCCTGGCAATCCTGAGTACTGTAAGGAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37122
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061361 None None 513 22 44
ENSDART00000061365 Nonsense 1168 2230 22 43
ENSDART00000075262 Nonsense 1168 2154 22 41
ENSDART00000122056 None None 261 None 9
ENSDART00000125333 None None 485 None 11
Genomic Location (Zv9):
Chromosome 20 (position 38833056)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 38905468
GRCz11 20 38808347
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTATTGCCATCGCGGTTTCTGAGCATGTGGAGAACGCAGGGGTTCATTCT[G/T]GAGACGCCACACTGGTGACTCCTCCACAGGACATTAACCAGAAAACCATG
Long Flanking Sequence:
TTGATCTAACTTCAAGAAATTAACACATTTCTGTTGTGCAGACAAATATAAAAACAAAAAACTGTTAATCATAGAAATGATTTGGTTTATTAATTGTTTATCAGTATCAGTAATAGTTGTTTATTGTATAACTGATTGACTGATGTACTCTTATCAGTCCACATTATATTAGATACTTGCATGCTTATCTCCTTTAAATTCATATTTATTTGCAGTATTGTCTATTTTAATACAAAACTATCCATTTAATGACTAAAAGCATTCCTAATGTGTCTTTTATTTAACCTTTGAATTCTGTGGTCCTGTATTGTACACTGTCTATCTGTGTAAGATGTTCAAATCTATTATGATGGCAATTTATGTTTGGCACTGTCAGTTTAGTAATGTTTATTGATGGTGTTTTTGACTCTCAGGAGATTGATGTGGACGCCGTGGCCTGTGATGGAGAGGTTATTGCCATCGCGGTTTCTGAGCATGTGGAGAACGCAGGGGTTCATTCT[G/T]GAGACGCCACACTGGTGACTCCTCCACAGGACATTAACCAGAAAACCATGGAGCGCATTAAGATGATCGTTCATGCTATTGGGCAGGAGCTTCAGGTCACTGGCCCGTTCAACCTGCAGCTCATTGCCAAGGTTGGTTACTTGCCTTTAAATTACATTTAGGATGTGTTTCTCAGATATTTGCTTCTGAAACAAATGCTATATTTATACAAATGCAATTTCGTCTTAATACAGCCTTATCCACTATGTTTATGAAAAATCTCGCTCTGTACACACAACAAAAATAATTTTAGAAGCAAGAACTAGCTATGAATTGGAGTACATTTAGAGTGTATTTACATTACATTATGCGATATTAAATAAATGTAAAAATTTTAACTTAAACTTTAAATCAGGATTTATTTATAAACTAATAAGATTGCATTGAATGAGAGAAACAAAACATAATGTTTAAGATGGCTGCAGCAATTTCCATTTTTAATCTTAAAATCCAGCCAGCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23778
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061361 None None 513 27 44
ENSDART00000061365 Nonsense 1465 2230 27 43
ENSDART00000075262 Nonsense 1465 2154 27 41
ENSDART00000122056 None None 261 None 9
ENSDART00000125333 None None 485 None 11
Genomic Location (Zv9):
Chromosome 20 (position 38828264)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 38900676
GRCz11 20 38803555
KASP Assay ID:
2261-4751.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAATTGGACAGGCTCCTCGCGTGAAGACACATGTAGACAGCATGACCTCA[C/T]AGAAACTCATCCGTTTGCCAGGTAAGTGTGGTCTCTTGCATCCTTTCAGT
Long Flanking Sequence:
TAATAATTATAATATTAATAGAAAATCATTCTAAAATTATTAATTATTATTAATATTATTGTATTTGTAACAATAATTAATATTTATTAGTAGATAAAAATAAATGTATAGAAAGAACAAAATAAAGCATAATTATAAATAACAACAACTATTATGATTATTATTATTTTAAACTTTATTTTCTATAGCGCTTTTAATGGTATATCCCAAAGCCATTCACAGGTTTTTTTTAAGGTAAAGATTCAAAGGAAAAAAGACCTAAAAAATATGATTATAAAAGGTAAATTTAACATCCTACATAAGACACCAAGAAATCACCTAAAAGCCATTCTGAAAAGTTTTAAGACCAGATTTTAAAACAATAAATGCTAAACACTAGAACGCAGTTTTATTGTATCACCCCTAAAACTAAAGATTGAAATGTATGTGGGTTTTGGCAGGCACTGAAGCAAATTGGACAGGCTCCTCGCGTGAAGACACATGTAGACAGCATGACCTCA[C/T]AGAAACTCATCCGTTTGCCAGGTAAGTGTGGTCTCTTGCATCCTTTCAGTTATTCAATACAATTTTTGTCAAAACAAATGAGTGTCCCTGCTGATTACCTTACCTGTAATGTAGCTGTTTGTGAATGTTAAAGTCTATGATGTTTTAAAAATCAAAGTGCTCGATAAATACAGTATCATTTTACAATAAGGTTGTATTATGTTAACTAACATAAACAAACAACTAACCACAAATTTATTACATCGTTTATTCATCTTTGTTAAGGTTAATAAATAGAATTTGTTTGTTGTTGGTTCATTTACTTAGTGCATTAACTAATGATAACAAACATTAGTTGGGTTGTAATAATGCATTAGTAAGTGTTGTGAGCAATGATTAACTGATTAATAAATGCTGTACAGTTATTTTTCATTTTTAGTTCATGTTAGTAAATACATTAATGAATCCTTATCTTAAAGTCCAAAATAAAAGCAATTCTTCCTGCAGTTTTGTGTTGTGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37121
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061361 Essential Splice Site 327 513 36 44
ENSDART00000061365 None None 2230 None 43
ENSDART00000075262 None None 2154 None 41
ENSDART00000122056 None None 261 None 9
ENSDART00000125333 Essential Splice Site 299 485 7 11
Genomic Location (Zv9):
Chromosome 20 (position 38822743)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 38895155
GRCz11 20 38798034
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTATATGCAGGTTTCAAAAGATCTACCATGCATCCCCAAAAGGCGTTTGG[T/A]AATGTGATGTGTATAGTTTTATCAAATCAAGATCTGTGTCTCGTGATTTC
Long Flanking Sequence:
TAAATGAATATGCTTGTTAATTCCAGCGTGTGATCGAGGCAATGACTCCTGAGCGCCCCCGTCAGGCGGCACCTGTTGATGTGGTCCGCAGTCGTGCCCCGAGCCCACGCCGCTCAGCTGGAGATGGACGGTTCATTCTGCCACCTCGTATCCACCGGTCATCTGATCCCGGCCTGCCTCCAGGTAGCGTAAAGTGCATAAAAGTATTTATGTATTTGCTCATGGCTTGTGCATGAGCTTGTGTGCCAAATGGACCACTGTTGTGTCAATAATTAGTTGGTCATTGGAAACGGTTTTAAATTAGACAGACAGTGGTTTATTTAGGCAATGGTAGCTTCTGTTTGCTAGCATCAGTTTTTGGTTTAAGCTTGCATGTCCCATTAACTTGCAAATGATTCAGCTAAACTGTTTGCTGGTCTAATTTGATCATGCTTCTTGTAAGATATGTTTTTATATGCAGGTTTCAAAAGATCTACCATGCATCCCCAAAAGGCGTTTGG[T/A]AATGTGATGTGTATAGTTTTATCAAATCAAGATCTGTGTCTCGTGATTTCGATTGAACATTCTGATCTGTTTTTTCTATCTTATTTTTCATTGAGAATATAACAATCTTGATAATTTTGTGCATGTATCATAATTGAATAATCTTACAGCCTCTGAAACTAAACTCTAAAATGTTCTTCAAATCTTTAAATCAGAAGTAATTCACCCAAAACGACAGTTGGATGTGGTGATTATTGCATTACATGTGTTACTGATTATTTTGCTGAAATGAAACCAGTCATTAAACAAATCTTTGGTAGGCCTGTCGATTAATTGCAGATTGTTATGTAATAGTGTAAATAGTGTATTTGCACAATGTTGTGATTAACCTAATTAATTGCAAAAATAGTCCACATTGTGCATCTGGACAGGAGACCCCATGGGAAAACTAGGTTGCTGTCGGAAGTGGTGTTAGTGAGGCCAGCTGGGAATGCTCAACCTGTCTGTGTGAGTCCTAATGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9368
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061361 None None 513 44 44
ENSDART00000061365 Nonsense 2228 2230 43 43
ENSDART00000075262 None 2148 2154 41 41
ENSDART00000122056 None None 261 None 9
ENSDART00000125333 None None 485 None 11
Genomic Location (Zv9):
Chromosome 20 (position 38813613)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 38886025
GRCz11 20 38788904
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCAGGCAGAGAACGGGATGTATATTCGGATGGCACTACTGGCTACTGTAT[T/A]GGGGCGATGAAGGGACYATAATGGTTCAGTCTTGACATTTGGCARTAAAG
Long Flanking Sequence:
CAAGAAGGTCGCTGGTTCGAGCCTCGGCTGGGTCAGTTGGCATTTCTGTGTGGAGTTTGCATGTTCTTCCCATGTTCACGTGGGTTTCCTCCGGGTGCTCCGGTATCCCCCACAAGTCCAAAGACGTGGTATAGGTGAATTGGGTAAGCTAAATTGCTTGTAGCGTATGTGTGTGAATAAGTGTGTATGGATGTTTCCCAGTGATGGGTTGCAGCTGGAAGCGCATCTGTTGCGTAAAACATATGCTGGCATAGTTGGCGGTTCATTCCGCTGTGGCGACCCCAGAGCGGAAAATAAAATTAATGAATGAAAAATGTAAATATAATATTTGATAAATCCTAATGGAGAATTATTGCAGAATCACTACTTCCAAAAGTGGATGGACATTTATTCATTTTATTTTATTTTCAGTGTGGAAGTGGACACAGATCCTCGGGCTGCTTACTTCCGGCAGGCAGAGAACGGGATGTATATTCGGATGGCACTACTGGCTACTGTAT[T/A]GGGGCGATGAAGGGACCATAATGGTTCAGTCTTGACATTTGGCAGTAAAGGGAAATATTTTATTGCTTACTGATGTGATTCCGTGTTTATTGTTCACTCTATATTGCTGCATTAAGTGAGATTTGTGGGTTGAAGTACCCAGAATTGTCTTTCATTCCGGTATTGACCACAATAACATTCCATATTGAGTATTTTACCTAAAACACGCACATTAAATCAACCACAGTGGAGTGTGGTTTGACATTTTTTGTTTGTTTGTTTTTTTCATTTATTGTAGTGCTCTAGCATGTGTAGAGAATTGCTCAAGTGTCATTTCAGTGTCTTTAAACTTGCAAACAGTTCTACAACTACATATTTTACTGTTATAAATGCAAATACTTTATTCTTTTCTTGTCCATTTACAACAATGCAGATGTATTTTCATGTCACCATATTCATTTTTTCCTATCCAATTGGGACCAGACTTTAGTAACCCAATCCTCTCAGATAAATAGATAGTG
Associated Phenotype:
Not determined