ZMP
lats1
Ensembl ID:
ZFIN ID:
Description:
serine/threonine-protein kinase LATS1 [Source:RefSeq peptide;Acc:NP_001018346]
Human Orthologue:
LATS1
Human Description:
LATS, large tumor suppressor, homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:6514]
Mouse Orthologue:
Lats1
Mouse Description:
large tumor suppressor Gene [Source:MGI Symbol;Acc:MGI:1333883]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa36934 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa36934
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000027119 | Essential Splice Site | 119 | 1068 | None | 8 |
| ENSDART00000081949 | Essential Splice Site | 119 | 1105 | None | 9 |
| ENSDART00000109321 | Essential Splice Site | 119 | 632 | None | 6 |
Genomic Location (Zv9):
Chromosome 20 (position 1288460)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 1244325 |
| GRCz11 | 20 | 1265151 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGACAGCAGCAAACACACACTCCAGACGCAGGAGCCCGGCTTTGATGAGG[T/C]AATGCAGCTGGTTGAGTTTTAAAGGGGCAGTTCACGCAAACATGAAAATC
Long Flanking Sequence:
AAAAGAATGAATGAATGACATTATTTGTTTATTTTTGTTGATGACCGCTCATCAGTGTTTCCTTCAGTTTGCAGTTGAAACAGACGCTGGATTCTGGACCGCTTCGCTTTTCACCGCCTTGGCACTTAACATATGCTTTTACATGAGGAGGGCCGAGAAACCCGAGGGATACAGACAAATGCGACCCAAGACGTTCCCTGCCAGCAACAACAGCGGCAACAGTCAGCAAATGCTGCAGGAGATCCGAGAGAGCCTGCGAAACCTCTCCCCGTCCTCCAATGCGTCCAAGCCGGAGCAGAGCTCAGGGAAGGGCCCGCCGGATGAGTCCAGACAGCAAGGGCGCAGCACCAACCCCAGAAACTCCCACCACCACAGAGCCCTGCAGGAGATCCGCAAATCCCTGCAGCCGTTTGCCCACGACAGCTCCTCCAGCGGAGACAACAGCTCCGCAGACAGCAGCAAACACACACTCCAGACGCAGGAGCCCGGCTTTGATGAGG[T/C]AATGCAGCTGGTTGAGTTTTAAAGGGGCAGTTCACGCAAACATGAAAATCAGCTAGGATGTCAATTTCCACAAATTTACATGGAAGTGAGCCTTGTCAAGCATGGTTTTACACAAATTCCAAATTGGTCCTCTGCTTTTAACCCATCCTAAGAGCATGCACACAAATACACAGTGAGCATGACTTCCAGAGGAATGGGAGTGGAACCTGCAACCTTTCGATTACAGCCTTTAGGGTAAGCATTTATTAAAACTATTTGTTATAATCAGAATTAATAAAAACTTGCAGAAACACTTTGATTGACATTCCCCCTTTGTACGTGTCATCAGAGGGGGAAAGCCACGCCCACTAGTGAGTAGTGACCATGGCTGTTTCTCAATACCAAGTACGCAAAGTTCAGACTTGGAAGAACGAACTCCCGATGACAGAAATAGAACGGCAGTTTACTTTATAGCGTCACTTACCTCACCATGGATTTATCGGTTTCACTGTACATTAACA
Associated Phenotype:
Not determined