ZMP
si:ch211-171h4.3
Ensembl ID:
ZFIN ID:
Description:
Novel kinase protein [Source:UniProtKB/TrEMBL;Acc:B8JL89]
Human Orthologue:
SBK2
Human Description:
SH3-binding domain kinase family, member 2 [Source:HGNC Symbol;Acc:34416]
Mouse Orthologue:
Sbk2
Mouse Description:
SH3-binding domain kinase family, member 2 Gene [Source:MGI Symbol;Acc:MGI:2685925]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa36792 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa43239 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa36792
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000004375 | Essential Splice Site | 118 | 336 | 3 | 4 |
| ENSDART00000145319 | Essential Splice Site | 118 | 238 | 3 | 4 |
Genomic Location (Zv9):
Chromosome 19 (position 11042369)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 10500908 |
| GRCz11 | 19 | 10419833 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAGCAGCCCTGCCTTTATGGTGACCTCTATGATGTCATCGTTCCTGAGG[T/C]ACGTTTCATGCATCTAAACAATGACTGGTCATGATGATTGAAATTAAACA
Long Flanking Sequence:
CATTTTGAGGGATGTAACCAATAACAATGGTCCTAATTAATTTTCTGTGCAGCATTTTTAATTTCCCAAGAATGTCCAAGAATCTCAAACAGTCCACATATTGATAAACAATGTTATGATGGCTGTTTTAACATTAAGATCTGATTAAAATGTCTCTTTTTACCACTATGAAATATTTTGACAACAAGCAGGGAATGTTTATGGGCCAATGACATCGCCACATCTAAATGGTTAATACCAATTCTTCTTTCTGTATCTTTGACTGATTATTTCTCTAAATCTGTTTTGTAATCTAGGAACCCCAATGGCCCTTAAGTTCTTCCTGCGAGACTCTACCTGTCTCCTGTCATTTCTGAGGGAGTATAATCTCTCTTTGGCCTTCTGCAAGCACCCCTCACTTACCTCAGCTTTGGGTATCGCTTTCTCCACTCCCACTCACTATGTGTTCGCCCAGCAGCCCTGCCTTTATGGTGACCTCTATGATGTCATCGTTCCTGAGG[T/C]ACGTTTCATGCATCTAAACAATGACTGGTCATGATGATTGAAATTAAACACGTCAAAGCTGATTCGAGAAAATCTCTCAACCTTTAAAACCCATTAAATCAGGGGTGTCCAAGCTTGTCCACTGTCCTGCACTGTCCTGTTAGCTCTGACCTTGGTGCTGAGTTTACAACAAGGCTGAAACCCGGAGCACAGCGAGAGGCAGGAGAAAATAGATATCAAATCACAAATGTAAACGGTAGCAGAACCATGAACTGCTTTACATGTTAAAATCAATGTCTCAAAATCAATACAAGACTAAGAGGGCAACTAGTGAAGCTGTTGGAGTACAGGAGTAATGTGAGACCGAGATGATTTATGTGATAACACATGCAGCAGAGTTTTGGAAGTATTGTAAAATCTTGAGAGAATTAGCAGGAACTTTTACGCATCCTCCATTCTTGCAGTCTTGAGGTTTGGAATTGAACTTTGGCAGTTGATGATGACATTACACAAGAACACGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa43239
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000004375 | Nonsense | 245 | 336 | 4 | 4 |
| ENSDART00000145319 | None | None | 238 | None | 4 |
Genomic Location (Zv9):
Chromosome 19 (position 11039031)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 10497570 |
| GRCz11 | 19 | 10416495 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGTCTGTGGATCCCTGTACGGACAGCTGGGCATTGGGCATTTTAATCTA[T/G]GCCATGCTGATGGGGAGCCTTCCATGGTCTGAGACTGTTAAAGACAACAC
Long Flanking Sequence:
TCACTGCTTTAATCCATTAAAGTTTGAAGTGCTTAAGTAAGGGATGTCCAATCCTACTGCAACGTGTAGCTCAAATTGGACATCCCAGTCTTAAGTACATTTTTGATTTCTTGATTGCAGGTTGGTCTGGAAGAGAGCCGTACCCAAGGAGTGGCTTCTCAGATCAGCGGTGCCCTCTCTCACCTCCATTCCCTTGGCTTTGTCCATCGTGATGTTAAGCCAGAGAACATCTTTCTATGCGATCGCGACTGCCGCTGGGTCAAGCTTGGCGATTTTGGCATGGTGAAAGCTGCAGGGACTAGGGTCCCGTGTGTGTGGTACAGCTCCCCATACTGCACGCCTGAGGCTGAGATAGCAAAGAAAAAGGTGGAGAGCGATTCAGGAGACACAGATGTGGATGACAATGGGAACAAGCTAAATGTGGACTTTGGCAAGACCCAAAGGATTTTGGTGTCTGTGGATCCCTGTACGGACAGCTGGGCATTGGGCATTTTAATCTA[T/G]GCCATGCTGATGGGGAGCCTTCCATGGTCTGAGACTGTTAAAGACAACACTGCATATAAAGGCTATCTACAGTGGAGCAAATGGGAAAGTTCTGCATCAGAAGATCAATCCGAGGACCTCTATCAGTTGGCACCACAGTTTGGGGCATTCACTCCTCTTGTAGCCTCTCTTTTTAGGTCCCTGCTCCATCCACTGTCCAGACTTCGTGGCCGGCCAGATGAAGTAGAGAAGTACCTTGGGGGAGCTTGGCTTCTGGACAAGGATGTCAGTGGGTGATACGTCAAAGAAAGGACAAGTCTGAGAATAGTAGATTGTTGTTATTTGGTCATTCCCTCTTTAGTGGGAAAAATGGTGATGACTTCTTGGAAGAGGTTCCAATGGTAACACACATGAACTCTACAGAGGAGGAGACAAGGTGTATAGGAATACCGAAAAACTTGGGCCTCAATCCACAGTCCGGCAACATTACTGCACTCCGAAACAATGTGCAATGACTGTAA
Associated Phenotype:
Not determined