Busch Lab

ZMP

eea1

Ensembl ID:
ENSDARG00000062868
ZFIN IDs:
ZDB-GENE-041008-68, ZDB-GENE-041111-270
Description:
Novel protein similar to H.sapiens EEA1, early endosome antigen 1 (EEA1) [Source:UniProtKB/TrEMBL;Ac
Human Orthologue:
EEA1
Human Description:
early endosome antigen 1 [Source:HGNC Symbol;Acc:3185]
Mouse Orthologue:
Eea1
Mouse Description:
early endosome antigen 1 Gene [Source:MGI Symbol;Acc:MGI:2442192]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa29005 Nonsense Mutation detected in F1 DNA Not yet available
sa36607 Nonsense Available for shipment Available now
sa44886 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa29005
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091349 Nonsense 242 1398 9 30
ENSDART00000141800 Nonsense 242 811 9 19
ENSDART00000142527 None None 255 None 5
Genomic Location (Zv9):
Chromosome 18 (position 15531445)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15883857
GRCz11 18 15852369
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACATGACCCGAGAGCGAGAGGAGGAGTCAGAGCGCCTCAAAGGCCAATA[T/G]GAGCAGCTGCAGGCCAACTTCACTACCTCAGAGGTACAGATGGCTAAATA
Long Flanking Sequence:
TTGAACAAAAAGCTGCTCAGCTTGCGACCGAGATAGTTGGTAAGCTTAGAAGGAAAGTTCCAGCATTTTATATTTACAGTAAATATAAAGTAAATCCGGCCTGTCCAATTTTCCCATCTCAGACATCAAATCTCGCTACGATGAGGAGAAAAGTATGAGAGAAGCTTTGGAGCAGAGACTGGCCAACTTAAACCAAGATATGCAAAAAGAAAAACAGGAGAAGGAGAAACTGTCGGCAGAGCTGGTAACGTCACACTTATTGTCTGGTGGTAATGAATGAGCTTGCATTCTCTCAGCTGCTGCTGCCCATACTTCATCAACTTCTTACCTCATCAATCTTTCCCGGCCTAATCCTGTCTGTCACTGGCTCTCCTCCAGCTCCAGAGGCCGGGTGTGGAAGATGTGGAGGTGTTGAAGAAAGAGCTGGTGCAGGTGCAGACGCTCATGGACAACATGACCCGAGAGCGAGAGGAGGAGTCAGAGCGCCTCAAAGGCCAATA[T/G]GAGCAGCTGCAGGCCAACTTCACTACCTCAGAGGTACAGATGGCTAAATATTAAAATTGTTAATAATCCTTTTAATTCATTTCAACTGTGTTTGTATAGCACTTTTAACAATATTTATTGATTCAAAGCAGCTTTATAAAAGGTGCACATTATTCAAATCAGAAAAGTCAGAACACCTCAAATCATACACCTTAGCAGTAGTCAGACTTTTTTAACATGTGTATTTTTGAGCTTCATGCGGATTATGTGCAAAACATGTATAGCAGGTGTGAAGTGCACACGAGTTTATTAAAAGCTTTCCAGTAGTGCGCTTGGGGTGGTGCATTCATTGCGGTCAGCATTATCAGCTTGTTTGTTATTTGAAATATATTAGCATATGATCCATCTGAACTGGAACATGTATTAATATTGAAATTTTATTCATGTGAGGTACATAAAGACAGGTGAAGTGGGCTACTGACTAAATGTCAGAAGCCTTTAACACACCTTGAACATTCATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36607
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091349 Nonsense 395 1398 11 30
ENSDART00000141800 Nonsense 395 811 11 19
ENSDART00000142527 None None 255 None 5
Genomic Location (Zv9):
Chromosome 18 (position 15542653)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15895065
GRCz11 18 15863577
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAAGGCAGAGCGGAAACAACTTCAACAGCAGAGGGAGGATAAAGAAAAC[C/T]AGGGCCTGCAGCAACAGAGTGAGATCAGCCAGGTCAGTAAGAGATGCTAA
Long Flanking Sequence:
TTTTGTCAGCATTCAAAAACACTGTTATAAAATGCTCATGTTTTGGTATTCTGTGCTGGCGGCCGGTGGTCTGATGAAAAAGCTTGTTGTATTGCATTCTTACTGTTGCCATGAAACAAAAGTTTGTATAAATGAATTGGTCATATTAAAAAAAACTGAATAGCAATGAATGTAATCACTCTGCCACTCCTCAGGCTTTGTCAGAGAAATTATCTCGTAAAGAGAAGGAGAATCAGGAACTGGAGGAGCGTCTGGGTCACGAACAGGCCTCTAAGAAGAGTCTTCAGGCTAATCTGCATCAGAAAGAGCTGGAGCTCCAGGAGAGTCGAGCACGGGTGTCTTCAGGAGAAGCAGCTCTCAGTCGAGCACAGGCTGAATTAACTGAACGTGGGGAAGAGGCTGCACGACTCAGACGAGAGCTGGGCGAGCTGGAGAAGAACCAGCAGGAGCTGAAGGCAGAGCGGAAACAACTTCAACAGCAGAGGGAGGATAAAGAAAAC[C/T]AGGGCCTGCAGCAACAGAGTGAGATCAGCCAGGTCAGTAAGAGATGCTAATAAAAGATGATTCAACCCTTTTCTTCAGAATCAGATTAATCTGTCCTTTTAGTTTAGAATCTAATTTATTATGTCGAAATCAGATCTATCTATACTTTAGTTCAGAATCCATCCATTCTTTAGTACTGAATTAGATCCATCCATCCTTTTGTTTAGAAACTAATTCATCAATTCTTTGAATTTAATTGAAAGGGTCTTTAAAGGTATAGTTAACTAAAAAACTTAACATTTCTTCATCATTTACTCATATTCAAGTGGTTGGAAAAAAGAAGCCAATGACATTCTTATTAGGAATGAGCTAAAAATAAACTATGGTAGAAAATGGCTGTTTTTCCCAACGTTCTTTAGTAAATCTTTTTGTTCAACAGAAGAAAGAAACAAGTGGCAGGATAAGTAAACAACTTGTTTCTTTAAGTTTAGAAACAAATACATCAATTTAGAATCAAATCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44886
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091349 Essential Splice Site 1143 1398 24 30
ENSDART00000141800 None None 811 None 19
ENSDART00000142527 None None 255 None 5
Genomic Location (Zv9):
Chromosome 18 (position 15554276)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15906688
GRCz11 18 15875200
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAACAAACTGTCTGCTGATCTCAAAACACTGGCTGAGAAGAATGAGAAG[G/A]TTAGACCCCAAAACACATTGAAATTCACATTAACAATCATGTAATGTGTA
Long Flanking Sequence:
TATTGGCCATGCAGGTGTGCGAGGAGAAGTTGGTTCTTGCTCAGGAGGAGCTGGTGACCAACAGGAACCAGCTCAGTGCTTACGAAACCCAAATCCAGGAGCTGAAGACGGGCCACACAGCGATGGAGATAGACCTGAGCAAGAGAGACGAGAAGATCAAACAGCAAGTGGAGACTCTGCAGAAGCTCCAGAAACAACAGGTAACAGAACAAGCCTGAGAAATCACACTTGTGCCCTCAAGCAAGACTTTGAATCACAGATTCTGAAGGTTACAGAAATATTTGTCAGTCATAAATTATATTTGCAGATTAGCACAGACAAATCGTGTGCTATTTTATGATCTGACTGGGTCTTTGTGTCTTTTGAAGGGACAAACAGAGGAGCAGCTGAAGAAGGAGAAAGCTCAATGCGAGGAGCTGAGAGAGAGTCAAAGCGCCCTGGAAAAGGACAAAAACAAACTGTCTGCTGATCTCAAAACACTGGCTGAGAAGAATGAGAAG[G/A]TTAGACCCCAAAACACATTGAAATTCACATTAACAATCATGTAATGTGTATTTATATAGCGCATTTATTGTGTGTGGTCATACACCCAAAAATCTTCACAGTCATTAGTGGAGTCTCCCCACACCACCACCAGTTTGCAGCATCCACTTGGATGATGCGATGGCAGCTACAGAACAATGGTGCCAGTGCACTCACCAAACACCAGCTATAGGTGGATTGGAGAGCCCTAATAGTAAGGGCAGATAGAGGGACTTTGGCCAGAACACCGGGGTTAAACTCCTACTCTTTACGAGAAGTGCCATGGGATTTTTAATGACAACAGAAAGTCAAGACCTCGGTTCAACGTCTCATCCGAAAGACGGCGCCCACTGACAGTGTAGTGTCCCCTTCACTTTTACAGGGGCATATGGACTCACACAGACCAAAGGTTGAGCGCTCCTTTCTGGCCTCTCTAACACAACTTCCAACAGCAACCTAGTTTTCCCATGTGGTGTCTTGTC
Associated Phenotype:
Not determined